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obesity, died, exercise, longevity

J Kelly Smith
Cardiovascular disease is the main cause of death in the United States. Although it is recognized that moderate intensity long-term exercise can decrease the chances of dying from cardiovascular disease by favorably modifying risk factors such as hypertension, obesity, hyperlipidemia, and insulin resistance, physical activity also enhances longevity by mechanisms independent of these risk factors. This review briefly summarizes what is known about the inflammatory nature of atherosclerosis and how long-term aerobic exercise can reduce the atherogenic activity of endothelial cells, blood mononuclear cells, and adipose tissue...
December 1, 2010: Cardiovascular & Hematological Disorders Drug Targets
Wilma J Nusselder, Oscar H Franco, Anna Peeters, Johan P Mackenbach
BACKGROUND: Non-smoking, having a normal weight and increased levels of physical activity are perhaps the three key factors for preventing cardiovascular disease (CVD). However, the relative effects of these factors on healthy longevity have not been well described. We aimed to calculate and compare the effects of non-smoking, normal weight and physical activity in middle-aged populations on life expectancy with and without cardiovascular disease. METHODS: Using multi-state life tables and data from the Framingham Heart Study (n = 4634) we calculated the effects of three heart healthy behaviours among populations aged 50 years and over on life expectancy with and without cardiovascular disease...
2009: BMC Public Health
Pedro R Zaros, Carla E M Romero Pires, Mauricio Bacci, Camila Moraes, Angelina Zanesco
BACKGROUND: Evidences have showed that the incidence of arterial hypertension is greater in postmenopausal women as compared to premenopausal. Physical inactivity has been implicated as a major contributor to weight gain and abdominal obesity in postmenopausal women and the incidence of cardiovascular disease increases dramatically after menopause. Additionally, more women than men die each year of coronary heart disease and are twice as likely as men to die within the first year after a heart attack...
2009: BMC Women's Health
R S Paffenbarger, R T Hyde, A L Wing, I M Lee, D L Jung, J B Kampert
BACKGROUND: Recent trends toward increasing physical exercise, stopping cigarette smoking, and avoiding obesity may increase longevity. We analyzed changes in the lifestyles of Harvard College alumni and the associations of these changes with mortality. METHODS: Men who were 45 to 84 years of age in 1977 and who had reported no life-threatening disease on questionnaires completed in 1962 or 1966 and again in 1977 were classified according to changes in lifestyle characteristics between the first and second questionnaires...
February 25, 1993: New England Journal of Medicine
F W Booth, W F MacKenzie, M J Seider, E W Gould
The purpose of this study was to determine whether daily running lengthens the life-span of animals dying prematurely due to cardiovascular disease. We used a strain of rat that is genetically hypertensive and obese and is reported to develop atherosclerosis (Exp. Mol. Pathol. 19: 53--60, 1973). These animals were divided into three groups consisting of runners exercised daily on treadmills from an early age life, food-restricted sedentary rats, and libitum eaters that were sedentary. This latter group had significantly higher average daily food intakes and body weights than either of the other two groups...
October 1980: Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
K H Cooper, A G Christen
In the late 1960's, preventive health care began to gain in popularity in the United States and the movement carried over into the 1970's. During this time, sizable decreases in deaths from heart disease, strokes, and accidents have been noted. As a result, the lowest death rate in the history of this country (8.9 per 1000) occurred in both 1975 and 1976. Since 1970, an increase in longevity has been documented and it can be said that Americans are living longer--not just longer but hopefully better! People are beginning to learn that "it is not so much that we die, we kill ourselves!" With proper weight, diet, and exercise, avoiding tobacco, early detection and treatment of high blood pressure, use of seat belts, and control of stimulants and drugs, thousands of lives are being saved annually...
July 1978: Dental Clinics of North America
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