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https://www.readbyqxmd.com/read/29917252/comparison-of-complications-between-peripheral-arm-ports-and-central-chest-ports-a-meta-analysis
#1
REVIEW
Shanshan Wu, Wanjiao Li, Qiongxiao Zhang, Shuting Li, Lizi Wang
AIM: To compare peripheral arm ports versus central chest ports in complication rates. BACKGROUND: Late complications of arm ports versus chest ports, including catheter-related infection, venous thrombosis and catheter obstruction, remain controversial. DESIGN: A meta-analysis conducted following the Cochrane handbook. DATA SOURCES: Studies published between 1950 - August 2017 were searched through Pubmed, Embase, Web of science and Cochrane library...
June 19, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29916838/simvastatin-reverses-multiple-myeloma-serum-induced-prothrombotic-phenotype-in-endothelial-cells-via-erk-1-2-signalling-pathway
#2
Rujiao Dong, Guibo Ma, Shunji Zhang, Yujuan Gao, Shuchuan Liu, Yanhua Su
: The introduction of new agents in multiple myeloma therapy has increased the overall response rate and improved clinical outcomes, but the increased risk of thrombotic complications impairs the quality of life of patient and the optimal thromboprophylaxis remains unknown. Increasing evidence has shown that statins can prevent venous thrombosis. Hence, we investigated the effects of simvastatin on multiple myeloma serum-related haemostatic imbalance in endothelial cells in vitro. The effects of simvastatin on procoagulant and anticoagulant protein expression were assessed on mixed multiple myeloma serum-treated human umbilical vein endothelial cells (HUVECs)...
June 18, 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29916259/polymorphisms-c677t-and-a1298c-of-mthfr-gene-homocysteine-levels-and-prothrombotic-biomarkers-in-coronary-and-pulmonary-thromboembolic-disease
#3
Eulo Lupi-Herrera, María Elena Soto-López, Antonio de Jesús Lugo-Dimas, Marcela Elizabeth Núñez-Martínez, Ricardo Gamboa, Claudia Huesca-Gómez, Lilia Mercedes Sierra-Galán, Verónica Guarner-Lans
The activity of the enzyme methylenetetrahydrofolate reductase (MTHFR) determines homocysteine (Hcy) levels, and polymorphisms in its gene affect the activity of the enzyme. Changes in the enzyme's activity may lead to a higher susceptibility to develop arterial and venous thromboembolic disease. The aim was to analyze the relationship between the C677T and A1298C polymorphisms of MTHFR, Hcy levels, and prothrombotic biomarkers in pulmonary embolism (PE) and acute myocardial ischemia (AMI). Clinical files of patients with thromboembolic diseases having complete data and whose doctor had requested an assay to determine the polymorphisms of the MTHFR gene, Hcy levels, and prothrombotic biomarkers were studied to search for the correlation between mutations of the MTHFR gene and Hcy levels in the different diseases...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29914813/balloon-angioplasty-for-symptomatic-inferior-vena-cava-aneurysm
#4
Kenneth Walsh, David O'Connor, Michael Wilderman, Anjali Ratnathicam, Gregory Simonian, Massimo M Napolitano
Aneurysms of the inferior vena cava (IVC) are uncommon. Symptomatic patients usually present with thrombosis and venous obstruction. Classification is based on location and the presence or absence of congenital IVC interruption. Treatment options include observation, open surgical resection, and endovascular modalities, of which coil embolization and stent graft placement have previously been described. We report the case of a patient with a 5.0-cm infrarenal IVC aneurysm and associated congenital stenosis who successfully underwent balloon angioplasty...
June 15, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29914404/significantly-different-clinical-features-between-hypertriglyceridemia-and-biliary-acute-pancreatitis-a-retrospective-study-of-730-patients-from-a-tertiary-center
#5
Xiaoyao Li, Lu Ke, Jie Dong, Bo Ye, Lei Meng, Wenjian Mao, Qi Yang, Weiqin Li, Jieshou Li
BACKGROUND: Unlike western world, gallstones and hypertriglyceridemia (HTG) are among the first two etiologies of acute pancreatitis (AP) in China. But yet, detailed differences in clinical features and outcomes between hypertriglyceridemia and biliary acute pancreatitis have not been well described. METHODS: This retrospective study enrolled 730 acute pancreatitis patients from July 1, 2013 to October 1, 2016 in Jinling Hospital. The causes of the study patients were defined according to specific diagnostic criteria...
June 19, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29913446/segmentation-of-dilated-hemorrhoidal-veins-in-hemorrhoidal-disease
#6
Lucio Díaz-Flores, Ricardo Gutiérrez, Miriam González-Gómez, Pino García, Francisco J Sáez, Lucio Díaz-Flores, José Luis Carrasco, Juan F Madrid
Vein segmentation is a vascular remodeling process mainly studied in experimental conditions and linked to hemodynamic factors, with clinical implications. The aim of this work is to assess the morphologic characteristics, associated findings, and mechanisms that participate in vein segmentation in humans. To this end, we examined 156 surgically obtained cases of hemorrhoidal disease. Segmentation occurred in 65 and was most prominent in 15, which were selected for serial sections, immunohistochemistry, and immunofluorescence procedures...
June 18, 2018: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/29912675/insufficient-evidence-to-conclude-that-neutrophil-to-lymphocyte-ratio-predicts-deep-venous-thrombosis
#7
Pavel Poredoš
No abstract text is available yet for this article.
June 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29910857/obesity-is-not-associated-with-an-increased-risk-of-portal-vein-thrombosis-in-cirrhotic-patients
#8
Alan Zakko, Paul T Kroner, Rooma Nankani, Raffi Karagozian
Aim: To determine the impact of obesity on development of portal vein thrombosis in cirrhotic patients. Background: Cirrhosis is a known risk factor for portal vein thrombosis (PVT). Evidence also points to obesity as being a risk factor for venous thromboembolism. Limited information is available on how obesity impacts the development of PVT in cirrhotic patients. Methods: This was a retrospective cohort study using the 2013 National Inpatient Sample...
2018: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/29909930/interventional-radiology-management-of-vascular-obstruction
#9
REVIEW
Marilyn Dunn, Brian A Scansen
Vascular obstructions in small animals have numerous etiologies and variable signs depending on location and chronicity. The decision to treat and by which method (medical, interventional, surgical) can be challenging. A combined approach of catheter-directed thrombolysis, angioplasty, or vascular stenting may be most appropriate for acute thrombosis, though optimal therapeutic strategies are undefined in this population. The role of embolic trapping devices in animals is uncertain. Chronic cases of vascular obstruction, with collateral flow and neither ischemia nor venous congestion manifest, may be conservatively managed...
June 15, 2018: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/29909860/outcomes-and-associated-factors-in-malpractice-litigation-involving-inferior-vena-cava-filters
#10
REVIEW
Kenny Oh, Anil Hingorani
OBJECTIVE: Placement of inferior vena cava (IVC) filters is a controversial focus of medical malpractice. Clinicians currently have little information to guide them regarding key issues and outcomes in litigation. In this retrospective legal case review, we analyzed the factors associated with malpractice actions involving IVC filters. METHODS: The legal databases LexisNexis and Westlaw were searched from 1967 to 2016 for all published legal cases in the United States involving placement of IVC filters...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29909853/stent-patency-in-patients-with-advanced-chronic-venous-disease-and-nonthrombotic-iliac-vein-lesions
#11
Syed Ali Rizvi, Enrico Ascher, Anil Hingorani, Natalie Marks
OBJECTIVE: Midterm patency results of iliac vein stents placed for nonthrombotic iliac vein lesions (NIVLs) are not widely known. Previously published studies involving large series of patients with iliac vein stent placement have failed to clearly demonstrate the outcomes for patients with NIVLs and advanced disease. To further study this issue, we reviewed our series of 268 iliac vein stents placed for NIVLs. METHODS: Retrospective analysis was performed of 210 patients who underwent common or external iliac vein angioplasty and stent placement procedures between January 2013 and December 2014...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29909851/may-thurner-syndrome-and-the-risk-of-pulmonary-embolism-in-patients-with-acute-deep-venous-thrombosis
#12
Song Jin, Ziqiang Sun, Xiaoqin Li, Tao Jian, Xing Jin, Sheng Li, Guodong Wang, Chong Ma, Kai Cui, Peng Xu
OBJECTIVE: Pulmonary embolism (PE) is the most common complication of deep venous thrombosis (DVT). May-Thurner syndrome (MTS) is known to increase the risk of DVT, but an association between MTS and PE has not been established. This study investigated an association between MTS and the risk of PE in patients with acute lower extremity DVT. METHODS: Between June 2014 and September 2016, there were 112 patients with DVT at our hospital who underwent venous angiography and computed tomography pulmonary angiography...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29907222/venous-thrombosis-following-pancreaticoduodenectomy-with-venous-resection
#13
Somala Mohammed, Jose E Mendez-Reyes, Amy McElhany, Daniel Gonzales-Luna, George Van Buren, Daniel S Bland, Nicole Villafane-Ferriol, Jeanne A Pierzynski, Charles A West, Eric J Silberfein, William E Fisher
BACKGROUND: Addition of en bloc segmental venous reconstruction (VR) to pancreaticoduodenectomy (PD) for venous involvement of pancreatic tumors increases the complexity of the operation and may increase complications. The long-term mesenteric venous patency rate and oncologic outcome has not been well defined. METHODS: Our prospective database was reviewed to assess 90-day postoperative outcomes for patients who underwent PD or PD + VR (September 2004-June 2016)...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29907123/overcoming-heparin-resistance-in-pregnant-women-with-antithrombin-deficiency-a-case-report-and-review-of-the-literature
#14
Panagiotis Tsikouras, Anna Christoforidou, Anastasia Bothou, Dorelia Deuteraiou, Xanthoula Anthoulaki, Anna Chalkidou, Stefanos Zervoudis, Georgios Galazios
BACKGROUND: The risk of thromboembolic events during pregnancy in patients with antithrombin deficiency is increased. Preventing thromboembolic events during pregnancy in the case of antithrombin deficiency is still a matter of concern. CASE PRESENTATION: We present a case of a 19-year-old primigravida Greek Pomak woman, who was diagnosed as having congenital antithrombin deficiency. She had a history of recurrent miscarriages and a family history of thrombosis...
June 16, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29906522/evaluation-of-venous-thromboembolic-complications-in-patients-operated-on-for-pelvic-fracture
#15
Candice Ostrowka, Stéphanie Bonhomme, Pomme Jouffroy, Guillaume Riouallon
INTRODUCTION: Fractures of the pelvis (acetabulum and pelvic ring) are complex in both radiological diagnosis and therapeutic management. They show high risk of thrombosis, with variable rates of venous thromboembolic complications in the literature, ranging from 10% to 50%, with 0.5-10% risk of fatal pulmonary embolism. The objective of the present study was to determine the rate of venous thromboembolic events in a consecutive cohort of pelvic fracture and to attempt to identify thromboembolic risk factors in this population...
June 12, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29905046/-effectiveness-of-high-strength-suture-fixation-in-treatment-of-patellar-transverse-fracture
#16
Jian Wang, Xiaobo Tang, Peilong Dong, Zhiyun Li
Objective: To explore the effectiveness of high strength suture fixation in treatment of patellar transverse fracture. Methods: Between June 2014 and June 2016, 38 patients with the patellar transverse fracture were treated with high strength suture internal fixation. There were 24 males and 14 females with the age of 26 to 64 years (mean, 45 years). There were 6 cases of accident injury and 32 cases of crashing injury. The time interval between injury and surgery was 2-8 days (mean, 5 days)...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29904405/predictive-value-of-platelet-aggregation-rate-in-postpartum-deep-venous-thrombosis-and-its-possible-mechanism
#17
Mingxia Sun, Chongdong Liu, Na Zhao, Kaikai Meng, Zhenyu Zhang
The present study investigated the predictive value of the platelet aggregation rate in postpartum deep venous thrombosis and its possible mechanism. From January 2014 to January 2016, 23 patients with postpartum deep vein thrombosis of lower extremity treated in the Department of Obstetrics of Beijing Chaoyang Hospital were as assigned as the observation group. At the same time, 25 cases with normal recovery were assigned as the control group. Blood samples were collected from all the subjects. The platelet aggregation rate was measured using a platelet aggregation apparatus...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29904039/an-unusual-cause-of-cauda-equina-syndrome-lumbar-epidural-venous-engorgement
#18
Husam A AlTahan, Roaa R Amer, Areej A Madani, Eman A Bakhsh
BACKGROUND Epidural venous plexus (EVP) engorgement occurs due to many conditions, so it can be easily misdiagnosed. This becomes problematic when the diagnosis requires prompt treatment for a good outcome, especially when it results in cauda equina syndrome (CES). We report a case of extensive iliocaval thrombosis leading to epidural venous plexus and ascending lumbar vein engorgement as an outcome of deep venous thrombosis (DVT) due to probable adverse effects of oral combined contraceptive pills (OCCP). CASE REPORT A 42-year-old woman presented to a rural medical facility with bilateral lower-limb swelling and skin darkening for 2 days...
June 15, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29903393/one-year-prognosis-of-non-traumatic-cortical-subarachnoid-haemorrhage-a-prospective-series-of-34-patients
#19
R F Galiano Blancart, G Fortea, A Pampliega Pérez, S Martí, V Parkhutik, A V Sánchez Cruz, C Soriano, D Geffner Sclarsky, M T Pérez Saldaña, N López Hernández, I Beltrán, A Lago Martín
INTRODUCTION: Cortical subarachnoid haemorrhage (cSAH) has multiple aetiologies. No prospective study has reported the long-term progression of the condition. The objective of this study is to describe the clinical and aetiological characteristics of patients with cSAH and to gain insight into prognosis. METHODS: We performed a prospective, observational, multi-centre study. Data on clinical and radiological variables were collected; during a one-year follow-up period, we recorded data on mortality, dependence, rebleeding, and the appearance of dementia...
June 11, 2018: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/29902281/circulating-immune-complexome-analysis-identified-anti-tubulin-%C3%AE-1c-as-an-inflammation-associated-autoantibody-with-promising-diagnostic-value-for-behcet-s-disease
#20
Yongjing Cheng, Xiaozhen Zhao, Yuling Chen, Yuhui Li, Rulin Jia, Lei Zhu, Cibo Huang, Xiaolin Sun, Haiteng Deng, Zhanguo Li
BACKGROUND: Behcet's disease (BD) is a chronic, multisystem-involved vasculitis and its pathogenesis remains elusive. No specific serological markers for BD diagnosis have been established. Identification of novel diagnostic biomarkers will be helpful in timely diagnostic and treatment for Behcet's disease. OBJECTIVE: To screen novel autoantigens or autoantibodies with potential diagnostic value in circulating immune complexes (CICs) from BD patients. METHODS: A proteomic strategy for immune complexome analysis was developed, in which CICs were separated from serum sample of 10 BD patients and 10 healthy controls and then subjected to Orbitrap mass spectrometry for autoantigen profiling...
2018: PloS One
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