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diabetes depression randomized

Josefin Sundh, Scott Montgomery, Mikael Hasselgren, Mary Kämpe, Christer Janson, Björn Ställberg, Karin Lisspers
Health status is a prognostic factor included in the assessment of chronic obstructive pulmonary disease (COPD). The aim of our study was to examine the associations of clinical factors with change in health status over a 7-year follow-up period. In 2005, 970 randomly selected primary and secondary care patients with a COPD diagnosis completed questionnaires including the Clinical COPD Questionnaire (CCQ); and in 2012, 413 completed the CCQ questionnaire again. Linear regression used difference in mean total CCQ score between 2005 and 2012 as the dependent variable...
October 20, 2016: NPJ Primary Care Respiratory Medicine
Peter Rijnbeek
Massive numbers of electronic health records are currently being collected globally, including structured data in the form of diagnoses, medications, laboratory test results, and unstructured data contained in clinical narratives. This opens unprecedented possibilities for research and ultimately patient care. However, actual use of these databases in a multi-center study is severely hampered by a variety of challenges, e.g., each database has a different database structure and uses different terminology systems...
September 2016: Journal of Hypertension
Christina M DuBois, Rachel A Millstein, Christopher M Celano, Deborah J Wexler, Jeff C Huffman
OBJECTIVE: Positive psychological attributes (eg, optimism) have been associated with a healthier lifestyle and superior medical outcomes in patients with type 2 diabetes; however, there has been minimal study of behavioral interventions that target positive psychological constructs in this population. Accordingly, we developed a novel, telephone-based, 12-week positive psychology intervention and assessed its feasibility and short-term impact in adults with type 2 diabetes and suboptimal health behavior adherence...
2016: Primary Care Companion to CNS Disorders
Jean-Pierre Michel
Already in the 90s, Khachaturian stated that postponing dementia onset by five years would decrease the prevalence of the late onset dementia by 50%. After two decades of lack of success in dementia drug discovery and development, and knowing that worldwide, currently 36 million patients have been diagnosed with Alzheimer's disease, a number that will double by 2030 and triple by 2050, the World Health Organization and the Alzheimer's Disease International declared that prevention of cognitive decline was a 'public health priority...
September 2016: Korean Journal of Family Medicine
Richard O White, Rosette J Chakkalakal, Caroline A Presley, Aihua Bian, Jonathan S Schildcrout, Kenneth A Wallston, Shari Barto, Sunil Kripalani, Russell Rothman
Patient-provider communication is modifiable and is linked to diabetes outcomes. The association of communication quality with medical mistrust is unknown. We examined these factors within the context of a low-literacy/numeracy-focused intervention to improve diabetes care, using baseline data from diverse patients enrolled in a randomized trial of a health communication intervention. Demographics, measures of health communication (Communication Assessment Tool [CAT], Interpersonal Processes of Care survey [IPC-18]), health literacy (Short Test of Functional Health Literacy in Adults), depression, medical mistrust, and glycemic control were ascertained...
2016: Journal of Health Communication
Peter Rijnbeek
Massive numbers of electronic health records are currently being collected globally, including structured data in the form of diagnoses, medications, laboratory test results, and unstructured data contained in clinical narratives. This opens unprecedented possibilities for research and ultimately patient care. However, actual use of these databases in a multi-center study is severely hampered by a variety of challenges, e.g., each database has a different database structure and uses different terminology systems...
September 2016: Journal of Hypertension
Douglas Gunzler, Martha Sajatovic, Richard McCormick, Adam Perzynski, Charles Thomas, Stephanie Kanuch, Kristin A Cassidy, Edna Fuentes-Casiano, Neal Dawson
OBJECTIVE: Care for people with serious mental illness and diabetes is complicated by clinical heterogeneity. This cross-sectional analysis of 200 individuals with comorbid serious mental illness and diabetes explored differentiation between patient subgroups that were characterized on the basis of selected dimensions within a biopsychosocial framework. METHODS: Relationships between self-efficacy, treatment expectation, social support, and depression were first assessed via bivariate Spearman correlations among 200 individuals participating in a randomized controlled trial who had diabetes along with major depression, bipolar disorder, or schizophrenia...
September 15, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
Masoud Shafieinia, Alireza Hidarnia, Anoushirvan Kazemnejad, Reza Rajabi
BACKGROUND: Regular physical activity has been highlighted as an important factor in decreasing about 25 factors harmful to health, such as obesity, diabetes, heart failure, depression and osteoporosis. Female office workers, because of the long hours they stay seated in their workplace, are seriously threatened by immobility. The Theory of Planned Behavior has been successfully used several times to predict PA behaviorphysical activity (PA). The TPB studies also have identified perceived behavioral control as the key determinant of walking intentions...
June 2016: Asian Journal of Sports Medicine
Ye Chang, Xiaofan Guo, Liang Guo, Zhao Li, Hongmei Yang, Shasha Yu, Guozhe Sun, Yingxian Sun
This study aimed to comprehensively compare the general characteristics, lifestyles, serum parameters, ultrasonic cardiogram (UCG) parameters, depression, quality of life, and various comorbidities between empty nest and non-empty nest elderly among rural populations in northeast China. This analysis was based on our previous study which was conducted from January 2012 to August 2013, using a multistage, stratified, random cluster sampling scheme. The final analyzed sample consisted of 3208 participants aged no less than 60 years, which was further classified into three groups: non-empty nest group, empty nest group (living as a couple), and empty nest group (living alone)...
2016: International Journal of Environmental Research and Public Health
Casey L O'Brien, Chantal F Ski, David R Thompson, Gaye Moore, Serafino Mancuso, Alicia Jenkins, Glenn Ward, Richard J MacIsaac, Margaret Loh, Simon R Knowles, Susan L Rossell, David J Castle
BACKGROUND: After a diagnosis of diabetes mellitus, people not only have to cope with the physical aspects and common complications that require daily self-management, they are also faced with ongoing psychosocial challenges. Subsequently they find themselves having to navigate the health system to engage multidisciplinary supports; the combination of these factors often resulting in reduced health-related quality of life. To maintain optimal diabetes control, interventions need to incorporate psychosocial supports and a skill base for disease management...
2016: Trials
Kennedy U Amadi, Richard Uwakwe, Appolos C Ndukuba, Paul C Odinka, Monday N Igwe, Nicodemus K Obayi, Mark S Ezeme
BACKGROUND: Religion is a powerful coping strategy. Diabetes and depression are common conditions in our environment that induce psychological distress, thus requiring coping for better outcome. Studies indicate that increased religiosity is associated with better outcome in clinical and general populations. Therefore, studies of the distribution of religiosity and religious coping among these populations are essential to improve outcome. OBJECTIVES: To assess the association between religiosity, religious coping in depression and diabetes mellitus, and selected sociodemographic variables (age, gender and occupational status)...
June 2016: African Health Sciences
Vanesa Bellou, Lazaros Belbasis, Ioanna Tzoulaki, Lefkos T Middleton, John P A Ioannidis, Evangelos Evangelou
INTRODUCTION: Dementia is a heterogeneous neurodegenerative disease, whose etiology results from a complex interplay between environmental and genetic factors. METHODS: We searched PubMed to identify meta-analyses of observational studies that examined associations between nongenetic factors and dementia. We estimated the summary effect size using random-effects and fixed-effects model, the 95% CI, and the 95% prediction interval. We assessed the between-study heterogeneity (I-square), evidence of small-study effects, and excess significance...
September 4, 2016: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
Julie Ann Wagner, Angela Bermudez-Millan, Grace Damio, Sofia Segura-Perez, Jyoti Chhabra, Cunegundo Vergara, Richard Feinn, Rafael Perez-Escamilla
AIMS: To test the efficacy of a community health worker (CHW) delivered stress management (SM) intervention on psychosocial, glycemic, and cortisol outcomes among U.S. Latinos with type 2 diabetes. METHODS: A randomized, controlled trial compared CHW-delivered diabetes education (DE; one group session) to DE plus CHW-delivered SM (DE+SM; 8 group sessions). Psychosocial variables and urinary cortisol were measured at baseline and posttreatment. HbA1c was measured at baseline, posttreatment, and 3-month follow-up...
October 2016: Diabetes Research and Clinical Practice
Joseph M Unger, Cathee Till, Ian M Thompson, Catherine M Tangen, Phyllis J Goodman, Jason D Wright, William E Barlow, Scott D Ramsey, Lori M Minasian, Dawn L Hershman
BACKGROUND: Finasteride has been found to reduce the risk of low-grade prostate cancer but to have no impact on overall survival. The long-term adverse and beneficial consequences of finasteride have not been examined. METHODS: We used a linkage between data from the Prostate Cancer Prevention Trial (PCPT) and Medicare claims. Patients were examined by randomized study arm (finasteride vs placebo for 7 years) for long-term consequences of the intervention, including cardiac, endocrine, and sexual dysfunction, depression, diabetes, and benign prostatic hyperplasia (BPH)-related events...
December 2016: Journal of the National Cancer Institute
Chao-Wei Huang, Tzu-Wen Hong, Ying-Jing Wang, Ko-Chien Chen, Ju-Chun Pei, Tai-Yuan Chuang, Wen-Sung Lai, Sheng-Hong Tsai, Richard Chu, Wei-Cheng Chen, Lee-Yan Sheen, Satoru Takahashi, Shih-Torng Ding, Tang-Long Shen
BACKGROUND: A newly defined Cordyceps species, Ophiocordyceps formosana (O. formosana) has been implicated in multitudinous bioactivities, including lowering glucose and cholesterol levels and modulating the immune system. However, few literatures demonstrate sufficient evidence to support these proposed functions. Although the use of Cordyceps spp. has been previously addressed to improve insulin insensitivity and improve the detrimental symptoms of depression; its mechanistic nature remains unsettled...
2016: BMC Complementary and Alternative Medicine
Tessa Peasgood, Alan Brennan, Peter Mansell, Jackie Elliott, Hasan Basarir, Jen Kruger
INTRODUCTION: This study estimates health-related quality of life (HRQoL) or utility decrements associated with type 1 diabetes mellitus (T1DM) using data from a UK research program on the Dose Adjustment For Normal Eating (DAFNE) education program. METHODS: A wide range of data was collected from 2341 individuals who undertook a DAFNE course in 2009-2012, at baseline and for 2 subsequent years. We use fixed- and random-effects linear models to generate utility estimates for T1DM using different instruments: EQ-5D, SF-6D, and EQ-VAS...
November 2016: Medical Decision Making: An International Journal of the Society for Medical Decision Making
Satoshi Mizuno, Hidekazu Nishigori, Takashi Sugiyama, Fumiaki Takahashi, Noriyuki Iwama, Zen Watanabe, Kasumi Sakurai, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Ichiko Nishijima, Ikuma Fujiwara, Takahiro Arima, Shinichi Kuriyama, Hirohito Metoki, Kunihiko Nakai, Hidekuni Inadera, Nobuo Yaegashi
BACKGROUND: Social capital is generally defined as the quality and frequency of social interactions with relatives, neighbors, and society. Social capital refers to broad concepts of social interactions and structures in individuals, communities and societies such as trust (e.g., neighborhood trust, which is social cohesion with neighbors) and social support (e.g., emotional support, which is the level of the feeling of being loved). Studies during the last few decades have shown that there is a significant inverse association between social capital and the prevalences of diseases such as depression and acute coronary syndrome...
October 2016: Diabetes Research and Clinical Practice
Craig Leonardi, Jerry Bagel, Paul Yamauchi, David Pariser, Zhenyi Xu, Anders Moller, Marie Louise Osterdal, Linda Stein Gold
INTRODUCTION: Psoriasis has a major impact on patient quality of life, similar to that seen in other chronic diseases, eg, diabetes. Health-related quality of life (HRQoL) measures are commonly included in clinical trial designs, capturing the disease burden and therapeutic success of a treatment. In the randomized, double-blind, phase III PSO-FAST (<b>Pso</b>riasis vulgaris, a <b>F</b>our-week, vehicle-controlled, efficacy <b>A</b>nd <b>S</b>afety <b>T</b>rial) study (nCT01866163), fixed combination calcipotriene (Cal) 0...
August 1, 2016: Journal of Drugs in Dermatology: JDD
Sofia M Danna, Eva Graham, Rachel J Burns, Sonya S Deschênes, Norbert Schmitz
Depression and diabetes are independent risk factors for one another, and both are associated with increased risk of cognitive decline. Diabetes patients with lower cognitive function are more likely to suffer poorer health outcomes. However, the role of depression in cognitive decline among people with diabetes is not well understood. This systematic review assessed whether adults with comorbid diabetes and depression or depressive symptoms exhibit greater cognitive decline relative to individuals with diabetes alone...
2016: PloS One
W Xu, K Liu, Q T Lin, X J Ye, Y Lu, X X Zhang, L C Zhao, H C Gao, Z H Yan
OBJECTIVE: To establish and evaluate a rat model of diabetes comorbid depression, and observe alterations in expression of glial fibrillary acidic protein (GFAP) in several cerebral regions. METHODS: Eighteen Wistar rats were randomly divided into three groups, the control group (group CON, n=6), the diabetes mellitus group (group DM, n=6), and the diabetes comorbid depression group (group DD, n=6). Rats of group DM and group DD were injected intraperitoneally with STZ (64 mg/kg), the control rats received sham injections of citrate buffer alone...
August 2, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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