keyword
MENU ▼
Read by QxMD icon Read
search

insulin resistance stress randomized

keyword
https://www.readbyqxmd.com/read/28686006/mindfulness-based-stress-reduction-in-women-with-overweight-or-obesity-a-randomized-clinical-trial
#1
Nazia Raja-Khan, Katrina Agito, Julie Shah, Christy M Stetter, Theresa S Gustafson, Holly Socolow, Allen R Kunselman, Diane K Reibel, Richard S Legro
OBJECTIVE: To evaluate the feasibility and cardiometabolic effects of mindfulness-based stress reduction (MBSR) in women with overweight or obesity. METHODS: Eighty-six women with BMI ≥ 25 kg/m(2) were randomized to 8 weeks of MBSR or health education and followed for 16 weeks. The primary outcome was the Toronto Mindfulness Scale. Secondary outcomes included the Perceived Stress Scale-10, fasting glucose, and blood pressure. RESULTS: Compared to health education, the MBSR group demonstrated significantly improved mindfulness at 8 weeks (mean change from baseline, 4...
July 7, 2017: Obesity
https://www.readbyqxmd.com/read/28679140/the-effects-of-vitamin-d-supplementation-on-metabolic-status-of-patients-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-trial
#2
Maryam Maktabi, Maryam Chamani, Zatollah Asemi
Data on the effects of vitamin D supplementation on metabolic status of patients with polycystic ovary syndrome (PCOS) are scarce. The current study was conducted to evaluate the effects of vitamin D supplementation on metabolic status of patients with PCOS. This randomized double-blind, placebo-controlled trial was performed on 70 vitamin D-deficient (serum concentrations<20 ng/ml) women with phenotype B-PCOS according to the Rotterdam criteria aged 18-40 years old. Participants were randomly allocated into 2 groups to take either 50 000 IU vitamin D (n=35) or placebo (n=35) every 2 weeks for 12 weeks...
July 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28642082/clinical-trial-of-the-effects-of-vitamin-d-supplementation-on-psychological-symptoms-and-metabolic-profiles-in-maintenance-methadone-treatment-patients
#3
Amir Ghaderi, Hamid Reza Banafshe, Maryam Motmaen, Morad Rasouli-Azad, Fereshteh Bahmani, Zatollah Asemi
BACKGROUND: Vitamin D deficiency may be associated with some complications including nonspecific musculoskeletal pain and periodontal disease in maintenance methadone treatment (MMT) patients. This study was designed to determine the effect of vitamin D supplementation on psychological symptoms and metabolic profiles in MMT patients. METHODS: This randomized, double-blind, placebo-controlled, clinical trial was carried out among 68 MMT patients. Participants were randomly allocated to receive either 50,000IU vitamin D supplements (n=34) or placebo (n=34) every 2weeks for 12weeks...
June 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28619389/the-promising-effect-of-linagliptin-and-or-indole-3-carbinol-on-experimentally-induced-polycystic-ovarian-syndrome
#4
Ahmed M Kabel, Aisha H Al-Shehri, Rehab A Al-Talhi, Maaly A Abd Elmaaboud
Polycystic ovarian syndrome (PCOS) is one of the most common medical conditions that lead to female infertility worldwide. The aim of this study was to assess the effect of linagliptin and/or indole-3-carbinol (I3C) on PCOS in female rats. Fifty female Wistar rats were randomly allocated into five equal groups: Control group; Letrozole-induced PCOS group; Letrozole + Linagliptin group; Letrozole + I3C group and Letrozole + Linagliptin + I3C group. Body weight, body mass index, Lee index and ovarian indices were determined...
June 13, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28608320/chronic-treatment-with-prebiotics-probiotics-and-synbiotics-attenuated-cardiac-dysfunction-by-improving-cardiac-mitochondrial-dysfunction-in-male-obese-insulin-resistant-rats
#5
Wannipa Tunapong, Nattayaporn Apaijai, Sakawdaurn Yasom, Pongpan Tanajak, Keerati Wanchai, Titikorn Chunchai, Sasiwan Kerdphoo, Sathima Eaimworawuthikul, Parameth Thiennimitr, Anchalee Pongchaidecha, Anusorn Lungkaphin, Wasana Pratchayasakul, Siriporn C Chattipakorn, Nipon Chattipakorn
PURPOSE: In metabolic syndrome, the composition of gut microbiota has been disrupted, and is associated with left ventricular (LV) dysfunction. Several types of prebiotics, probiotics, and synbiotics have been shown to exert cardioprotection by restoring gut microbiota from dysbiosis and reducing systemic inflammation. However, the effects of prebiotics such as xylooligosaccharides (XOS); probiotics such as Lactobacillus paracasei STII01 HP4, and synbiotics on metabolic and LV function in obese insulin-resistant rats have not been investigated...
June 12, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28594573/activation-of-integrated-stress-response-and-metabolic-dysfunction-in-a-murine-model-of-sleep-apnea
#6
Abdelnaby Khalyfa, Zhuanhong Qiao, Alex Gileles-Hillel, Ahamed A Khalyfa, Mahzad Akbarpour, Brian Popko, David Gozal
BACKGROUND: Intermittent hypoxia (IH) induces activation of the integrated stress response (ISR), but its role in IH-induced visceral white adipose tissue (vWAT) insulin resistance in unknown. CHOP is activated by chronic ISR, while GADD34 dephosphorylates the subunit of translation initiation factor 2 (eIF2α), leading to termination of ISR. We hypothesized that CHOP/Gadd34 null mice would not manifest evidence of insulin resistance following IH exposures. METHODS: 8-week-old CHOP/GADD34-/- (DM) and wild type (WT) littermates were randomly assigned to IH or RA exposures for 6 weeks...
June 8, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28567018/acute-normobaric-hypoxia-increases-post-exercise-lipid-oxidation-in-healthy-males
#7
Liam P Kelly, Fabien A Basset
The primary objective of the current study was to determine the effect of moderate normobaric hypoxia exposure during constant load cycling on post-exercise energy metabolism recorded in normoxia. Indirect calorimetry was used to examine whole body substrate oxidation before, during, 40-60 min post, and 22 h after performing 60 min of cycling exercise at two different fractions of inspired oxygen (FIO2): (i) FIO2 = 0.2091 (normoxia) and (ii) FIO2 = 0.15 (hypoxia). Seven active healthy male participants (26 ± 4 years of age) completed both experimental trials in randomized order with a 7-day washout period to avoid carryover effects between conditions...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28541810/effects-of-a-carbohydrate-glutamine-and-antioxidant-enriched-oral-nutrition-supplement-on-major-surgery-induced-insulin-resistance-a-randomized-pilot-study
#8
Mireille F M van Stijn, Maarten R Soeters, Paul A M van Leeuwen, W H Schreurs, Margreet G Schoorl, Jos W R Twisk, Jean-Pascal De Bandt, Dominique Bonnefont-Rousselot, Luc Cynober, Mariette T Ackermans, Mireille J Serlie, Alexander P J Houdijk
BACKGROUND: Insulin resistance after surgery hampers recovery. Oxidative stress is shown to be involved in the occurrence of postoperative insulin resistance. Preoperative carbohydrate-rich oral nutrition supplements reduce but do not prevent insulin resistance. The aim of the present study was to investigate the effect of a carbohydrate-, glutamine-, and antioxidant-enriched preoperative oral nutrition supplement on postoperative insulin resistance. METHODS: A double-blind randomized controlled pilot study in 18 patients with rectal cancer, who received either the supplement (S) or the placebo (P) 15, 11, and 4 hours preoperatively, was conducted...
May 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28490725/effects-of-valsartan-and-amlodipine-on-oxidative-stress-in-type-2-diabetic-patients-with-hypertension-a-randomized-multicenter-study
#9
Hae Jin Kim, Seung Jin Han, Dae Jung Kim, Hak Chul Jang, Soo Lim, Sung Hee Choi, Yong Hyun Kim, Dong Hyun Shin, Se Hwa Kim, Tae Ho Kim, Yu Bae Ahn, Seung Hyun Ko, Nan Hee Kim, Ji A Seo, Ha Young Kim, Kwan Woo Lee
BACKGROUND/AIMS: Oxidative stress plays an important role in the pathogenesis and progression of diabetic complications and antagonists of renin-angiotensin system and amlodipine have been reported previously to reduce oxidative stress. In this study, we compared the changes in oxidative stress markers after valsartan and amlodipine treatment in type 2 diabetic patients with hypertension and compared the changes in metabolic parameters. METHODS: Type 2 diabetic subjects with hypertension 30 to 80 years of age who were not taking antihypertensive drugs were randomized into either valsartan (n = 33) or amlodipine (n = 35) groups and treated for 24 weeks...
May 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28459032/antiretroviral-therapy-induced-insulin-resistance-and-oxidative-deoxy-nucleic-acid-damage-in-human-immunodeficiency-virus-1-patients
#10
Vaishali Kolgiri Honnapurmath, V W Patil
BACKGROUND AND OBJECTIVES: Insulin resistance (IR) is frequent in human immunodeficiency virus (HIV) infection and may be related to antiretroviral therapy (ART). Increased oxidative stress parameters and carbonyl protein are linked to insulin sensitivity. The present study is aimed to determine IR, its association with oxidative deoxy nucleic acid (DNA) damage in HIV-1-infected patients with different ART status. MATERIALS AND METHODS: In this case-control study, a total 600 subjects were included...
March 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28347819/deferiprone-attenuates-inflammation-and-myocardial-fibrosis-in-diabetic-cardiomyopathy-rats
#11
Chunbo Zou, Xiaogang Liu, Rujuan Xie, Yushi Bao, Qing Jin, Xibei Jia, Li Li, Ruichan Liu
We attempted to investigate the therapeutic effects of deferiprone on DC rats and explore the underlying mechanism. Total 24 6-week-old male Wistar rats (weighing from 180 g to 220 g) were subjected to DC model construction and then randomly divided to three groups (8 rats per group): DC group, DC + 50 mg, and DC + 100 mg deferiprone treatment group. The 8 normal rats were considered as controls. After deferiprone treatment for 20 weeks, the blood samples were collected for the biochemical parameters test, including fasting glucose, HOMA-IR (homeostasis model assessment of the insulin resistance), serum iron, ferritin and transferrin saturation (TS)...
May 13, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28283863/clinical-and-metabolic-response-to-vitamin-d-supplementation-in-endometrial-hyperplasia-a-randomized-double-blind-placebo-controlled-trial
#12
Zohreh Tabassi, Sedigheh Bagheri, Mansooreh Samimi, Hamid Reza Gilasi, Fereshteh Bahmani, Maryam Chamani, Zatollah Asemi
There was inconsistent evidence showing that vitamin D intake may be associated with reduced cancer risk due to optimized metabolic profile and reduced oxidative stress. However, we are not aware of any study evaluating the effects of vitamin D supplementation on clinical response and metabolic status of patients with endometrial hyperplasia (EH). This research was done to evaluate the effects of vitamin D supplementation on clinical response and metabolic status of patients with EH. This randomized, double-blind, placebo-controlled trial was conducted among 60 women diagnosed with EH...
March 10, 2017: Hormones & Cancer
https://www.readbyqxmd.com/read/28212306/metabolic-effects-of-berries-with-structurally-diverse-anthocyanins
#13
John Overall, Sierra A Bonney, Mickey Wilson, Arnold Beermann, Mary H Grace, Debora Esposito, Mary Ann Lila, Slavko Komarnytsky
Overconsumption of energy dense foods and sedentary lifestyle are considered as major causes of obesity-associated insulin resistance and abnormal glucose metabolism. Results from both cohort studies and randomized trials suggested that anthocyanins from berries may lower metabolic risks, however these reports are equivocal. The present study was designed to examine effects of six berries with structurally diverse anthocyanin profiles (normalized to 400 µg/g total anthocyanin content) on development of metabolic risk factors in the C57BL/6 mouse model of polygenic obesity...
February 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28144458/grape-seed-extract-supplementation-and-the-effects-on-the-biomarkers-of-oxidative-stress-and-metabolic-profiles-in-female-volleyball-players-a-randomized-double-blind-placebo-controlled-clinical-trial
#14
Mohsen Taghizadeh, Elaheh Malekian, Mohammad Reza Memarzadeh, Ali Akbar Mohammadi, Zatollah Asemi
BACKGROUND: Only limited data are available for evaluating the effects of the administration of grape seed extract (GSE) on the metabolic status of female volleyball players. OBJECTIVES: This study was conducted to determine the effects of GSE administration on the metabolic status of female volleyball players. METHODS: This randomized, double-blind, placebo-controlled clinical trial was performed among 40 female volleyball players. The subjects were randomly divided into two groups, with members of the test group (n = 20) taking 300 mg of GSE twice a day for eight weeks and members of the control group (n = 20) taking a placebo pearl for the same period...
September 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28139216/integrated-stress-response-activation-by-sleep-fragmentation-during-late-gestation-in-mice-leads-to-emergence-of-adverse-metabolic-phenotype-in-offspring
#15
Wojciech Trzepizur, Abdelnaby Khalyfa, Zhuanhong Qiao, Brian Popko, David Gozal
BACKGROUND: Late gestational sleep fragmentation (SF) is highly prevalent particularly in obese women, and induces metabolic dysfunction in adult offspring mice. SF induces activation of the integrated stress response (ISR), which might be involved in metabolic disorders. We hypothesized that adult offspring of double mutant mice (DM) involving the critical ISR genes CHOP and GADD34 would be protected from developing obesity and insulin resistance following SF. METHODS: Time-pregnant CHOP/GADD34 DM and wild type (WT) mice were randomly assigned to sleep control (SC) or SF conditions during the last 5days of gestation...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28122931/long-term-vitamin-d-supplementation-affects-metabolic-status-in-vitamin-d-deficient-type-2-diabetic-patients-with-coronary-artery-disease
#16
RANDOMIZED CONTROLLED TRIAL
Alireza Farrokhian, Fariba Raygan, Fereshteh Bahmani, Hamid Reza Talari, Reza Esfandiari, Ahmad Esmaillzadeh, Zatollah Asemi
Background: Vitamin D might be beneficial in diabetic patients with coronary artery disease (CAD) through its favorable effects on metabolic profiles and biomarkers of inflammation and oxidative stress.Objective: This study was performed to examine the effects of 6 mo of vitamin D supplementation on metabolic status in diabetic patients with CAD.Methods: This randomized, double-blind, placebo-controlled clinical trial was conducted in 60 vitamin D-deficient diabetic patients with CAD aged 40-85 y. Subjects were randomly assigned into 2 groups to take either 50,000-IU vitamin D supplements (n = 30) or placebo (n = 30) every 2 wk for 6 mo...
March 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28073036/does-preoperative-oral-carbohydrate-treatment-reduce-the-postoperative-surgical-stress-response-in-lumbar-disc-surgery
#17
RANDOMIZED CONTROLLED TRIAL
Ozlem Korkmaz Dilmen, Ercument Yentur, Yusuf Tunali, Huriye Balci, Mois Bahar
OBJECTIVES: Surgical trauma produces metabolic and hormonal responses, which are characterized by insulin resistance. Due to extension of the preoperative fasting period, which increases the magnitude of postoperative insulin resistance, preoperative oral carbohydrates (POC) have been developed. PATIENTS AND METHODS: This prospective, randomized, controlled study was performed on 43 ASA I-II patients undergoing elective microsurgical lumbar discectomy. The intervention group received oral carbohydrate solution 800mL the night before and 400mL 2h prior to operation...
February 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27932354/longitudinal-impact-of-smoking-and-smoking-cessation-on-inflammatory-markers-of-cardiovascular-disease-risk
#18
Cecile C King, Megan E Piper, Adam D Gepner, Michael C Fiore, Timothy B Baker, James H Stein
OBJECTIVE: To evaluate longitudinal changes in 6 inflammatory markers that predict cardiovascular disease events among smokers making a quit attempt and to characterize their cross-sectional associations between smoking and smoking heaviness. APPROACH AND RESULTS: In a longitudinal cohort study of contemporary smokers (n=1652), we evaluated (1) independent associations of smoking heaviness markers (exhaled carbon monoxide, cigarettes/d, pack-years) with inflammatory markers (C-reactive protein, D-dimer, fibrinogen, urinary F2 isoprostane:creatinine [F2:Cr] ratio, white blood cell [WBC] count, myeloperoxidase) and (2) the effects of smoking cessation and continued smoking on these inflammatory markers after 1 year, among the 888 smokers who made an aided quit attempt as part of a randomized comparative effectiveness trial or standard care...
February 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27927601/probiotic-supplementation-in-diabetic-hemodialysis-patients-has-beneficial-metabolic-effects
#19
Alireza Soleimani, Malihe Zarrati Mojarrad, Fereshteh Bahmani, Mohsen Taghizadeh, Mohammad Ramezani, Maryam Tajabadi-Ebrahimi, Parvaneh Jafari, Ahmad Esmaillzadeh, Zatollah Asemi
This study determined the effects of probiotic supplementation on glycemic control, lipid concentrations, biomarkers of inflammation and oxidative stress in 60 diabetic patients on hemodialysis in a parallel randomized double-blind placebo-controlled clinical trial. Participants were initially matched based on sex, duration of dialysis and diabetes, body mass index and age. Subsequently, they were randomly divided into two groups to take either a capsule containing the probiotics Lactobacillus acidophilus, Lactobacillus casei and Bifidobacterium bifidum or placebo for 12 weeks...
December 4, 2016: Kidney International
https://www.readbyqxmd.com/read/27894971/aqueous-seed-extract-of-hunteria-umbellata-k-schum-hallier-f-apocynaceae-palliates-hyperglycemia-insulin-resistance-dyslipidemia-inflammation-and-oxidative-stress-in-high-fructose-diet-induced-metabolic-syndrome-in-rats
#20
T O Ajiboye, A A Hussaini, B Y Nafiu, O B Ibitoye
ETHNOPHARMACOLOGICAL RELEVANCE: Hunteria umbellata is used in the management and treatment of diabetes and obesity in Nigeria. This study evaluates the effect of aqueous seed extract of Hunteria umbellata on insulin resistance, dyslipidemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome MATERIALS AND METHODS: Rats were randomized into seven groups (A-G). Control (group A) and group C rats received control diet for nine weeks while rats in groups B, D - G were placed on high-fructose diet for 9 weeks...
February 23, 2017: Journal of Ethnopharmacology
keyword
keyword
110497
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"