keyword
https://read.qxmd.com/read/38539346/infantile-hemangiomas-of-the-head-and-neck-a-single-center-experience
#1
JOURNAL ARTICLE
Deniz Kizmazoglu, Dilek Ince, Yuksel Olgun, Emre Cecen, Handan Guleryuz, Taner Erdag, Nur Olgun
Background: Infantile hemangiomas (IHs) are the most common benign vascular tumors of infancy. Methods: We report our experiences with 248 patients with head and neck IHs. Results: The median admission age was 4 months, and the female/male ratio was 2.18. Among the cases, 45% were followed by no treatment. No local complications were observed in any of these patients. Propranolol was provided to all patients who received medical treatment. The median duration of treatment was 12 months (1-30 months), and the median follow-up period of all patients was 14 months (0-118 months)...
March 6, 2024: Children
https://read.qxmd.com/read/38469839/color-doppler-ultrasound-indices-as-predictors-of-propranolol-response-in-infantile-hemangioma-a-prospective-study
#2
JOURNAL ARTICLE
Vaibhav Pandey, Rathindra Nath Bera, Amit Nandan Dhar Diwedi, Om Prakash Singh, Preeti Tiwari
OBJECTIVE: To evaluate the utility of color Doppler ultrasonography in assessing infantile hemangioma response to treatment with oral propranolol. METHODS: A prospective study was conducted between January, 2016 and December, 2022, wherein children with symptomatic (ulceration, bleeding, pain and scarring) infantile hemangioma were given oral propranol (2 mg/kg per day in three divided doses) as outpatient therapy. The clinical response was assessed three months post-initiation of treatment (intermediate clinical response) and three months post-completion of treatment (final clinical response, FCR)...
March 15, 2024: Indian Pediatrics
https://read.qxmd.com/read/38469795/diffuse-colonic-capillary-hemangioma-mimicking-ulcerative-colitis
#3
JOURNAL ARTICLE
Marta García Calonge, Maria García Martínez, Óscar González Bernardo, Sabino Riestra
Inflammatory bowel disease (IBD) diagnosis requires clinical, laboratory, endoscopic and histologic findings, and sometimes it can become a challenge. An exhaustive differential diagnosis with infectious disease, immunodeficiencies, hematologic, neoplastic, or vascular diseases must be made1, since prognosis and treatment vary depending on etiology. We present the case of a 62-year-old man, with no personal history of interest, who undergoes a colonoscopy after a positive colorectal cancer screening test (fecal occult blood test)...
March 12, 2024: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/38463743/successful-treatment-of-ulcerated-hemangioma-with-diversion-colostomy-in-a-neonate-with-lumbar-syndrome
#4
Ananya Shah, Megha Tollefson, Edward S Ahn, Waleed Gibreel, Stephanie Polites
We present the case of a 3-week-old girl with LUMBAR syndrome, a rare condition involving segmental infantile hemangiomas (IH) in the lumbosacral region, myelopathy, and other congenital anomalies. The patient developed severe ulceration of a left buttock IH. Treatment included broad-spectrum antibiotics, debridement, and a laparoscopic temporary colostomy. Propranolol therapy, wound care, and fecal diversion led to successful healing of the ulceration. The report highlights the challenges of ulcerated IH in the perineal area due to exposure to urine and stool...
March 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38459633/neonatal-nasal-necrosis-case-series-and-brief-review
#5
Jamie L Karch, David Grand, Ariana G Diaz, Leah Belazarian, Julianne A Mann
There is limited information available on pressure-related neonatal nasal injuries. We present three neonates born with erythema and purpura of the nasal tip that subsequently ulcerated, then evolved into a thick eschar. Each healed well with conservative management but left behind significant scarring. The sharp demarcation and location of the lesions were suggestive of hypoxic tissue damage akin to halo scalp ring alopecia. Further investigation is necessary to elucidate the etiology and optimal management of this condition...
March 8, 2024: Pediatric Dermatology
https://read.qxmd.com/read/38370473/historical-and-contemporary-management-of-infantile-hemangiomas-a-single-center-experience
#6
JOURNAL ARTICLE
Yun Zou, Zhiping Wu, Pingliang Jin, Ronghua Fu, Jun Cheng, Hanxiang Bai, Mengyu Huang, Xiangqun Huang, Hua Yuan
Objective: This study explores the 22-year evolution of Infantile Hemangiomas (IHs) treatment strategies at a single-center hospital, aiming to establish an individualized IHs management protocol. Methods: Retrospective review of IHs infants 2000-2022 at the Department of Plastic Surgery, Jiangxi Provincial Children's Hospital. Results: In our study of 27,513 IHs cases, 72.2% were female, with the median age at first hospital visit being 25 days. The majority of cases had localized and superficial lesions primarily on the head, face, and neck (67...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38329175/the-prevalence-complications-and-risk-factors-for-infantile-hemangioma-a-systematic-review-and-meta-analysis
#7
REVIEW
Yuming Sun, Jinhong Zhao, Yu Meng, Xiangyue Luo, Chufeng Jiang, Guangtong Deng, Shaorong Lei
The epidemiological landscape of infantile hemangioma (IH) has been extensively explored through diverse data sources; however, a scarcity of systematically pooled and quantified evidence from comprehensive global studies persists. In this meta-analysis, we systematically review available literature to elucidate the prevalence, distribution of lesions, complications, and risk factors associated with IH. A meticulous search encompassing the Cochrane Library, PubMed, Embase, and Web of Science identified 3206 records, of which 55 studies met the inclusion criteria...
February 8, 2024: International Journal of Dermatology
https://read.qxmd.com/read/37975966/cavernous-hemangioma-of-the-lip-combined-treatment-with-intralesional-laser-and-surgery
#8
JOURNAL ARTICLE
Alberto Goldman, Uwe Wollina
Infantile cavernous hemangioma is a benign vascular tumor in childhood. Cavernous hemangiomas have a tendency of slow enlargement with subsequent complications such as ulceration and bleeding. We report a case of a large cavernous hemangioma affecting the median upper lip in an 11-year-old girl. The lesion was growing and painful on pressure. The patient felt stigmatized. Treatment was wished for by patient and parents. After careful examination including Doppler ultrasound, we suggested a combined approach...
November 17, 2023: Wiener Medizinische Wochenschrift
https://read.qxmd.com/read/37898939/phace-s-syndrome-early-diagnostics-in-the-maxillofacial-area
#9
JOURNAL ARTICLE
Natalia Kiseilyova, Lyudmila Yakovenko, Larisa Tyshko
OBJECTIVE: The aim: To determine the minimum criteria for early diagnosing PHACE(S) syndrome in neonates and infants with infantile hemangioma (IH) in the max¬illofacial area. PATIENTS AND METHODS: Materials and methods: A total of 26 asymptomatic children from 20 days to six months of aged with IH of more than 5 cm² in the maxillofacial area were included in this study. A medical record of patients clinical examination, Holter monitoring, echocardiographic ultrasound and magnetic resonance imaging (MRI) were analysed...
2023: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/37854254/partially-involuting-congenital-hemangioma-with-pyogenic-granuloma-induced-rapid-progression-following-incisional-biopsy-in-infancy-a-case-report
#10
Yuki Sasaki, Kosuke Ishikawa, Takahiro Miura, Emi Funayama, Yuhei Yamamoto, Taku Maeda
We present a case of partially involuting congenital hemangioma (PICH) that showed rapid growth with ulceration after incisional biopsy. PICH does not typically grow after birth. However, if growth occurs due to stimuli like biopsy, it is essential to consider the possibility of pyogenic granuloma complication.
October 2023: Clinical Case Reports
https://read.qxmd.com/read/37845188/clinical-characteristics-of-infantile-hemangiomas-with-aggressive-persistent-and-destructive-ulceration
#11
JOURNAL ARTICLE
Ayushi Gautam, Ilona J Frieden, Sonal D Shah, Patricia M Witman, Katya Harfmann, Flora Bradley, Francine Blei, Elena Pope, Anwar Alsumait, Deepti Gupta, Isabela Covelli, Jenna L Streicher, Colleen Cotton, Megha Tollefson, Henry Nguyen, Raegan Hunt, Amy Buros, Esteban Fernández Faith
BACKGROUND/OBJECTIVES: Ulceration is a common complication of infantile hemangioma (IH). Severe, persistent ulceration occurs in a minority of patients. This study aims to characterize the clinical features of IH with aggressive ulceration (AU). METHODS: Multicenter retrospective study of clinical features of IH with AU. RESULTS: Thirty-five patients with AU were identified and included in the study. The majority of AU occurred in segmental IH (23/35, 65%)...
October 16, 2023: Pediatric Dermatology
https://read.qxmd.com/read/37804648/intralesional-betamethasone-versus-oral-propranolol-for-localized-infantile-hemangiomas-of-the-lip
#12
JOURNAL ARTICLE
Shih-Jen Chang, Lei Chang, Hsiao-Fen Chang, Ying Shang, Yajing Qiu, Xiaoxi Lin
Infantile hemangiomas (IHs) of the lips are associated with an increased risk of incomplete involution and ulceration, causing disfigurement. Treatment with oral propranolol (OPT) has credible efficacy but takes months to complete. Thus, this study aimed to investigate the efficacy of intralesional betamethasone injection (IBI) as an alternative treatment for protruding localized IHs of the lips. To investigate the efficacies of OPT and IBI, we designed a prospective, noninferiority, parallel-group study. The primary outcome assessed was treatment response rate...
September 11, 2023: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/37692602/duodenal-hemangioma-as-a-rare-cause-of-gastrointestinal-bleeding-a-case-report-and-literature-review
#13
Osama N Dukmak, Mohammed Ayyad, Mahmoud Gabajah, Fida' Dabbas, Ayman Budair, Mohammad Emar, Mohamed Maraqa, Fahmi Joubran
Duodenal hemangiomas are benign vascular tumors caused by haphazard vascular proliferation within the duodenal wall. Although rare, duodenal hemangiomas could lead to rapidly progressive life-threatening gastrointestinal (GI) bleeding that requires urgent intervention. The diagnosis of duodenal hemangioma often requires direct visualization of the lesion either endoscopically or surgically, as well as histopathological examination. Treatment options include endoscopic resection, laser coagulation, sclerotherapy, or in a specific subset of patients, open or laparoscopic surgical intervention...
August 2023: Curēus
https://read.qxmd.com/read/37651201/urgent-treatment-of-complicated-ulcerated-infantile-hemangioma-with-%C3%AE-blockers-via-telemedicine-a-case-report
#14
JOURNAL ARTICLE
Olga Bogomolets, Magdalena Wierzbik-Strońska, Roman Hryshchenko, Catherine Bogomolets
Introduction: Infantile hemangiomas (IH) exacerbated by ulceration invariably necessitate hospitalization, although simple IHs are sometimes managed remotely. Furthermore, according to international regulations, β-blocker medication for such hemangiomas should be systemic and performed in a clinic, especially if there is infection and risk of bleeding. Case: War in Ukraine made it impossible to hospitalize and properly examine a patient with a complex ulcerated and infected IH, forcing us to administer β-blocker timolol therapy only through telemedicine...
August 31, 2023: Telemedicine Journal and E-health
https://read.qxmd.com/read/37602023/lobular-capillary-hemangioma-masquerading-as-pyogenic-granuloma-of-anterior-mandible-a-case-report
#15
C V Srinivedha, Dr Saurabh Simre, Abiskar Basnet, Sameer Pandey, Ashi Chug
Pyogenic granuloma (PG) is a reactive connective tissue disorder with female predilection, which exhibits a tumor-like mass with occasional bleeding and superficial ulceration. It most commonly occurs in the maxillary gingiva followed by the mandibular gingiva. It can also occur in extra gingival sites like buccal mucosa, labial mucosa, and palate. There are two histopathological types of PG, namely, a lobular capillary hemangioma (LCH) variant and a non-LCH variant. The various management methods include surgical resection or laser excision along with deep curettage, and there are various nonsurgical methods like local steroid injection, topical administration of various drugs, and sclerotherapy...
July 2023: Curēus
https://read.qxmd.com/read/37470332/mechanism-and-application-of-%C3%AE-adrenoceptor-blockers-in-soft-tissue-wound-healing
#16
REVIEW
Shasha Jia, Xueya Wang, Guowei Wang, Xiaojing Wang
Soft tissue damage stimulates sympathetic nerves to release large amounts of catecholamine hormones which bind to β-adrenergic receptors (β-ARs) on the cell membrane surface. It activates the downstream effector molecules and impairs soft tissue wound healing. β-blockers specifically inhibit β-ARs activation in acute/chronic skin lesions and ulcerative hemangiomas. They also accelerate soft tissue wound healing by shortening the duration of inflammation, speeding keratinocyte migration and reepithelialization, promoting wound contraction and angiogenesis, and inhibiting bacterial virulence effects...
July 20, 2023: Medicinal Research Reviews
https://read.qxmd.com/read/37451624/characteristics-and-complications-of-anogenital-infantile-hemangiomas-a-multicenter-retrospective-analysis
#17
JOURNAL ARTICLE
Justin D Arnold, SunJung Yoon, Nidhi Shah, Morgan Byrne, Lukas Kieswetter, Cathryn Sibbald, Irene Lara-Corrales, Neha Kinariwalla, Maria C Garzon, Mitchell Braun, Sonal D Shah, Ilona J Frieden, Nicole Travis, Carmen Liy Wong, Alan N Snyder, Lara Wine Lee, Erin K Collier, Marcia Hogeling, Esteban Fernandez Faith, Nicole DeVaul, Anna Yasmine Kirkorian
BACKGROUND: Infantile hemangiomas (IHs) of the anogenital region remain poorly characterized. OBJECTIVE: To examine the distribution, ulceration rate, and associated congenital anomalies of anogenital IHs. METHODS: Retrospective study at 8 tertiary referral centers. RESULTS: A total of 435 infants with an IH of the anogenital region were enrolled (of which, 319 [73%] were girls). Congenital anomalies were present in 6...
July 13, 2023: Journal of the American Academy of Dermatology
https://read.qxmd.com/read/37389387/propranolol-for-vascular-anomalies-efficacy-and-complications-in-pediatric-patients
#18
JOURNAL ARTICLE
Rahul Gupta
CONTEXT: Congenital vascular anomalies are classically subdivided into vascular tumors and vascular malformations. The role of propranolol in the regression of infantile hemangioma (IH), a vascular tumor, is well establishe. AIMS: This study aimed to analyze the therapeutic efficacy and complications associated with oral propranolol and adjuvant therapy in the treatment of vascular anomalies. SETTINGS AND DESIGN: A prospective interventional study was undertaken over 10 years duration extending from 2012 to 2022 at a tertiary care teaching institute...
2023: Journal of Indian Association of Pediatric Surgeons
https://read.qxmd.com/read/37289424/lobular-capillary-hemangioma-pyogenic-granuloma-of-the-gastrointestinal-tract-clinicopathologic-analysis-of-34-cases
#19
JOURNAL ARTICLE
Adam L Booth, Lysandra Voltaggio, Rebecca Waters, John Goldblum, Michael M Feely, Diana Agostini-Vulaj, Maryam Pezhouh, Raul S Gonzalez
OBJECTIVES: Lobular capillary hemangioma (LCH) rarely involves the gastrointestinal (GI) tract. This study describes clinicopathologic features of LCH in a cohort of GI cases. METHODS: We defined lobular capillary hemangioma as "a proliferation of capillary-sized blood vessels arranged at least focally in a lobular configuration," searched departmental archives for cases, and recorded clinicopathologic findings. RESULTS: We identified 34 GI tract LCHs from 16 men and 10 women; 4 patients had multiple lesions...
October 3, 2023: American Journal of Clinical Pathology
https://read.qxmd.com/read/37275108/conservative-treatment-of-head-and-neck-hemangiomas-using-intralesional-bleomycin
#20
JOURNAL ARTICLE
Ekta Narang, Neha Jain, Jaswinder Kaur, Suparna Roy, Jyoti Singh
BACKGROUND: Hemangiomas are vascular tumours and commonly occur in head and neck region. Complete treatment of these vascular swellings are often challenging. As surgical excision carries high risk of complications and poor cosmetic outcome, treatment is shifted more towards non-surgical modalities like steroid therapy, radiotherapy, chemotherapy and sclerotherapy. OBJECTIVE: To study the efficacy of intralesional Bleomycin sclerotherapy for head and neck hemangiomas...
June 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
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