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https://www.readbyqxmd.com/read/28527093/income-disparities-in-healthcare-use-remain-after-controlling-for-healthcare-need-evidence-from-swedish-register-data-on-psoriasis-and-psoriatic-arthritis
#1
Sofia Löfvendahl, Anna Jöud, Ingemar F Petersson, Elke Theander, Åke Svensson, Katarina Steen Carlsson
We used a southern Swedish cohort of psoriasis (PSO) and psoriatic arthritis (PsA) patients and population-based referents (N = 57,800) to investigate the influence of socioeconomic and demographic factors on the probability of healthcare use and on healthcare costs when controlling for need as measured by PSO/PsA and common additional morbidities such as diabetes, depression and myocardial infarction. People with PSO/PsA were identified by ICD-10 codes in the Skåne Healthcare Register 1998-2007. Resource use and costs for years 2008-2011 were retrieved from the Skåne Healthcare Register and the Swedish Prescribed Drug Register, and socioeconomic data were retrieved from Statistics Sweden...
May 19, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28515210/impact-of-perceived-control-on-all-cause-and-cardiovascular-disease-mortality-in-three-urban-populations-of-central-and-eastern-europe-the-hapiee-study
#2
Magdalena Kozela, Andrzej Pająk, Agnieszka Micek, Agnieszka Besala, Ruzena Kubinova, Sofia Malyutina, Abdonas Tamosiunas, Hynek Pikhart, Anne Peasey, Yuri Nikitin, Michael Marmot, Martin Bobak
BACKGROUND: Inverse associations between perceived control and cardiovascular disease (CVD) have been reported in studies from Western Europe and the USA. To assess this relationship across different populations, we investigated the association between perceived control and all-cause and CVD mortality in three population-based cohorts of Eastern European countries. METHODS: We analysed data from a prospective cohort study in random population samples in Krakow (Poland), Novosibirsk (Russia) and six Czech towns...
May 17, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28500616/significance-of-blood-neutrophil-to-lymphocyte-ratio-for-prognostic-stratification-of-patients-with-gastroesophageal-junction-adenocarcinoma-in-the-era-of-the-8th-edition-of-the-american-joint-committee-on-cancer-ajcc8-staging
#3
Alicia-Marie Conway, Zena Salih, George Papaxoinis, Kimberly Fletcher, Jamie Weaver, Ana Patrao, Robert Noble, Sofia Stamatopoulou, Vikki Owen-Holt, Wasat Mansoor
The prognosis of patients with gastroesophageal junction (GOJ) adenocarcinoma depends mainly on the clinical staging, as described by the new AJCC8 (American Joint Committee on Cancer 8th edition). Evidence suggests that peripheral blood neutrophil-to-lymphocyte ratio (NLR) may be of prognostic significance in patients with upper gastrointestinal cancers. We examined the prognostic significance of NLR in the era of the new AJCC8 staging system. In this single-centre cohort study, retrospective data on patients with operable GOJ adenocarcinoma treated with perioperative chemotherapy were analysed...
June 2017: Medical Oncology
https://www.readbyqxmd.com/read/28480012/exploring-the-impact-of-multidecadal-environmental-changes-on-the-population-genetic-structure-of-a-marine-primary-producer
#4
Nina Lundholm, Sofia Ribeiro, Anna Godhe, Lene Rostgaard Nielsen, Marianne Ellegaard
Many marine protists form resting stages that can remain viable in coastal sediments for several decades. Their long-term survival offers the possibility to explore the impact of changes in environmental conditions on population dynamics over multidecadal time scales. Resting stages of the phototrophic dinoflagellate Pentapharsodinium dalei were isolated and germinated from five layers in dated sediment cores from Koljö fjord, Sweden, spanning ca. 1910-2006. This fjord has, during the last century, experienced environmental fluctuations linked to hydrographic variability mainly driven by the North Atlantic Oscillation...
May 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28479971/reliability-validity-and-psychometric-properties-of-the-greek-translation-of-the-posttraumatic-stress-disorder-scale
#5
Konstantinos Kontoangelos, Sofia Tsiori, Garyfalia Poulakou, Konstantinos Protopapas, Ioannis Katsarolis, Vissaria Sakka, Dimitra Kavatha, Antonios Papadopoulos, Anastasia Antoniadou, Charalambos C Papageorgiou
The Greek version of the Davidson Trauma Scale (DTS) was developed to respond to the need of Greek-speaking individuals. The translated questionnaire was administered to 128 HIV outpatients (aged 37.1±9.1) and 166 control patients (aged 32.4±13.4). In addition to the DTS Greek scale, subjects were assessed with two other scales useful for assessing validity. For each factor analyses two components were extracted, based on Cattell's scree test. The two components solution accounted for 55.34% of the total variation in case of frequency variables and 61...
March 22, 2017: Mental Illness
https://www.readbyqxmd.com/read/28478701/exercise-habits-and-factors-associated-with-exercise-in-systemic-sclerosis-a-scleroderma-patient-centered-intervention-network-spin-cohort-study
#6
Marleine Azar, Danielle B Rice, Linda Kwakkenbos, Marie-Eve Carrier, Ian Shrier, Susan J Bartlett, Marie Hudson, Luc Mouthon, Serge Poiraudeau, Cornelia H M van den Ende, Sindhu R Johnson, Tatiana Sofia Rodriguez Reyna, Anne A Schouffoer, Joep Welling, Brett D Thombs
OBJECTIVE: Exercise is associated with improved health in many medical conditions. Little is known about the exercise habits of people with systemic sclerosis (SSc, or scleroderma). This study assessed the proportion of individuals with SSc who exercise and associations of demographic and disease variables with exercise. Additionally, the weekly amount of time spent exercising and the types of exercise performed were assessed among patients exercising. METHODS: The sample consisted of adult participants with SSc enrolled in the Scleroderma Patient-centered Intervention Network (SPIN) Cohort who completed baseline questionnaires from March 2014 through August 2015...
May 8, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28474340/doddering-but-dear-%C3%A2-even-in-the-eyes-of-young-children-age-stereotyping-and-prejudice-in-childhood-and-adolescence
#7
Christin-Melanie Vauclair, Ricardo Borges Rodrigues, Sibila Marques, Carla Sofia Esteves, Filipa Cunha, Filomena Gerardo
This study aims to explore age prejudice, and to examine age stereotyping in children and adolescents by adopting the Stereotype Content Model (SCM) as a theoretical framework. It was hypothesised that children are socialised into adopting an ambivalent representation of old age (socialisation hypothesis) and that this cognitive bias becomes weaker in adolescence due to greater cognitive maturity (developmental hypothesis). By analysing representative data from Portugal (European Social Survey; N = 2367), it was ascertained that the ambivalent age stereotype (higher evaluations of warmth than competence for older people) is indeed a shared social representation of older people in Portuguese society...
May 5, 2017: International Journal of Psychology: Journal International de Psychologie
https://www.readbyqxmd.com/read/28472138/ecological-value-of-macrophyte-cover-in-creating-habitat-for-microalgae-diatoms-and-zooplankton-rotifers-and-crustaceans-in-small-field-and-forest-water-bodies
#8
Sofia Celewicz-Gołdyn, Natalia Kuczyńska-Kippen
Due to their small area and shallow depth ponds are usually treated as a single sampling unit, while various microhabitats offer different environmental conditions. Thus, we tested the effect of different habitat types typically found within small ponds on the microalgae and zooplankton communities. We found that submerged macrophytes have the strongest impact on microalgae and zooplankton communities out of all the analysed habitats. Some epontic diatoms (e.g. Fragilaria dilatata, Cymbella affinis) and littoral-associated zooplankton species (e...
2017: PloS One
https://www.readbyqxmd.com/read/28453780/variation-in-maturity-onset-diabetes-of-the-young-genes-influence-response-to-interventions-for-diabetes-prevention
#9
Liana K Billings, Kathleen A Jablonski, A Sofia Warner, Yu-Chien Cheng, Jarred B McAteer, Laura Tipton, Alan R Shuldiner, David A Ehrmann, Alisa K Manning, Dana Dabelea, Paul W Franks, Steven E Kahn, Toni I Pollin, William C Knowler, David Altshuler, Jose C Florez
CONTEXT: Variation in genes that cause Maturity-Onset Diabetes of the Young (MODY) has been associated with diabetes incidence and glycemic traits. OBJECTIVES: This study aimed to determine whether genetic variation in MODY genes leads to differential responses to insulin-sensitizing interventions. DESIGN AND SETTING: This was a secondary analysis of a multicenter randomized clinical trial, the Diabetes Prevention Program (DPP), involving 27 U...
April 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28449073/genetics-of-phenotypic-plasticity-and-biomass-traits-in-hybrid-willows-across-contrasting-environments-and-years
#10
Sofia Berlin, Henrik R Hallingbäck, Friderike Beyer, Nils-Erik Nordh, Martin Weih, Ann-Christin Rönnberg-Wästljung
Background and Aims: Phenotypic plasticity can affect the geographical distribution of taxa and greatly impact the productivity of crops across contrasting and variable environments. The main objectives of this study were to identify genotype-phenotype associations in key biomass and phenology traits and the strength of phenotypic plasticity of these traits in a short-rotation coppice willow population across multiple years and contrasting environments to facilitate marker-assisted selection for these traits...
April 25, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28436117/early-introduction-of-oral-paricalcitol-in-renal-transplant-recipients-an-open-label-randomized-study
#11
Hege Kampen Pihlstrøm, Franscesca Gatti, Clara Hammarström, Ivar Anders Eide, Monika Kasprzycka, Junbai Wang, Guttorm Haraldsen, My Hanna Sofia Svensson, Karsten Midtvedt, Geir Mjøen, Dag Olav Dahle, Anders Hartmann, Hallvard Holdaas
In stable renal transplant recipients with hyperparathyroidism, previous studies have indicated that vitamin D agonist treatment might have anti-proteinuric effects. Animal studies indicate possible anti-fibrotic and anti-inflammatory effects. Early introduction of paricalcitol in de-novo renal transplant recipients might reduce proteinuria and prevent progressive allograft fibrosis. We performed a single-centre, prospective, randomized, open-label trial investigating effects of paricalcitol 2μg/day added to standard care...
April 24, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28424494/predictable-phenotypic-but-not-karyotypic-evolution-of-populations-with-contrasting-initial-history
#12
Pedro Simões, Inês Fragata, Sofia G Seabra, Gonçalo S Faria, Marta A Santos, Michael R Rose, Mauro Santos, Margarida Matos
The relative impact of selection, chance and history will determine the predictability of evolution. There is a lack of empirical research on this subject, particularly in sexual organisms. Here we use experimental evolution to test the predictability of evolution. We analyse the real-time evolution of Drosophila subobscura populations derived from contrasting European latitudes placed in a novel laboratory environment. Each natural population was sampled twice within a three-year interval. We study evolutionary responses at both phenotypic (life-history, morphological and physiological traits) and karyotypic levels for around 30 generations of laboratory culture...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28412475/potential-anti-inflammatory-effect-of-lqfm-021-in-carrageenan-induced-inflammation-the-role-of-nitric-oxide
#13
Iziara F Florentino, Daiany P B Silva, Dayane M Silva, Carina Sofia Cardoso, André L E Moreira, Clayton L Borges, Célia M de A Soares, Pablinny M Galdino, Luciano M Lião, Paulo C Ghedini, Ricardo Menegatti, Elson A Costa
The pyrazole compound LQFM-021 exhibits vasorelaxant, antinociceptive and anti-inflammatory activities. Furthermore, it has low toxicity, indicating that this compound may be considered to be a good prototype for the development of new analgesic/anti-inflammatory drugs. Therefore, the aim of this study was to investigate the potential anti-inflammatory activity of LQFM-021 using a model of carrageenan-induced inflammation as well as the mechanism of action and role of nitric oxide in this effect. Acute treatments with LQFM-021 (30 and 60 mg/kg p...
April 12, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28391709/immune-modulation-properties-of-herbal-plant-leaves-phyllanthus-niruri-aqueous-extract-on-immune-cells-of-tuberculosis-patient-in-vitro-study
#14
Denise Utami Putri, Ning Rintiswati, Marsetyawan Hne Soesatyo, Sofia Mubarika Haryana
Disease progression in Tuberculosis (TB) is dependent on host's immune system. Phyllanthus niruri, a traditional herb, has long been used to boost immune system in Indonesian society. This study aimed to observe the potential role of P. niruri in inducing immune cells activity in TB patients by in vitro approach. Peripheral blood mononuclear cells (PBMCs) and macrophages were collected from active pulmonary TB patients. After stimulation with graded doses of P. niruri aqueous extract, cell proliferation, phagocytic activity and nitric oxide (NO) release were analysed...
April 10, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28390435/inter-pregnancy-interval-and-pregnancy-outcomes-among-women-with-delayed-childbearing-protocol-for-a-systematic-review
#15
Mani Asgharpour, Sofia Villarreal, Laura Schummers, Jennifer Hutcheon, Dorothy Shaw, Wendy V Norman
BACKGROUND: Women in high resource nations are increasingly delaying childbearing until their thirties. Delayed childbearing poses challenges for the spacing of a woman's pregnancies. Inter-pregnancy intervals <12 months are associated with risk for adverse pregnancy outcome, yet increased maternal age at delivery is linked with increased risk. The optimal inter-pregnancy interval for older mothers is uncertain. This systematic review will aim to assess the relation between inter-pregnancy interval and perinatal and maternal health outcomes in women who delay childbearing to age 30 and older...
April 8, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28389975/assessment-of-apathy-minimising-the-effect-of-motor-dysfunctions-in-parkinson-s-disease-a-validation-study-of-the-dimensional-apathy-scale
#16
Gabriella Santangelo, Alfonsina D'Iorio, Fausta Piscopo, Sofia Cuoco, Katia Longo, Marianna Amboni, Chiara Baiano, Domenico Tafuri, Maria Teresa Pellecchia, Paolo Barone, Carmine Vitale
PURPOSE: Apathy is associated with motor symptoms in Parkinson's disease (PD); therefore, its evaluation could be influenced by motor disability. The Dimensional Apathy Scale (DAS) evaluates apathy excluding confounding effects of motor symptoms. The present study had three major aims: (a) to explore the psychometric properties of the DAS in non-demented PD patients; (b) to determine an optimal cut-off score of the DAS to identify apathetic PD patients; and (c) to determine a specific apathy profile in PD patients as compared to healthy controls (HC)...
April 7, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28388482/face-proprioception-does-not-modulate-access-to-visual-awareness-of-emotional-faces-in-a-continuous-flash-suppression-paradigm
#17
Sebastian Korb, Sofia A Osimo, Tiziano Suran, Ariel Goldstein, Raffaella Ida Rumiati
An important question in neuroscience is which multisensory information, presented outside of awareness, can influence the nature and speed of conscious access to our percepts. Recently, proprioceptive feedback of the hand was reported to lead to faster awareness of congruent hand images in a breaking continuous flash suppression (b-CFS) paradigm. Moreover, a vast literature suggests that spontaneous facial mimicry can improve emotion recognition, even without awareness of the stimulus face. However, integration of visual and proprioceptive information about the face to date has not been tested with CFS...
April 4, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28385278/intensive-care-nurses-experiences-of-infants-and-partners-presence-on-the-postoperative-ward-after-an-emergency-caesarean-section-an-interview-study
#18
Sofia Zwedberg, Matilda Huss, Emma Karlsson, Marie Poignant
It is evident that immediate skin-to-skin care after birth has the potential to improve breastfeeding outcomes and maternal satisfaction after a caesarean section; hence partners and infants should be present on the postoperative ward. OBJECTIVE: To investigate the intensive care nurses' experiences of having the infant and partner present on the postoperative ward after emergency caesarean sections. DESIGN: Interviews with semi-structured interviews were conducted and analysed using qualitative content analysis...
April 3, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28382781/heteronormativity-and-prostate-cancer-a-discursive-paper
#19
Daniel Kelly, Dikaios Sakellariou, Sarah Fry, Sofia Vougioukalou
AIMS AND OBJECTIVES: To discuss the risks that heteronormative assumptions play in prostate cancer care and how these may be addressed. BACKGROUND: There is international evidence to support the case that LGBT cancer patients are less likely to report poor health or self-disclose sexual orientation. Gender-specific cancers, such as prostate cancer, require particular interventions in terms of supportive care. These may include advice about side-effect management (such as incontinence or erectile dysfunction), treatment choices and social and emotional issues...
April 5, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28367127/alterations-of-intrinsic-brain-connectivity-patterns-in-depression-and-bipolar-disorders-a-critical-assessment-of-magnetoencephalography-based-evidence
#20
REVIEW
Golnoush Alamian, Ana-Sofía Hincapié, Etienne Combrisson, Thomas Thiery, Véronique Martel, Dmitrii Althukov, Karim Jerbi
Despite being the object of a thriving field of clinical research, the investigation of intrinsic brain network alterations in psychiatric illnesses is still in its early days. Because the pathological alterations are predominantly probed using functional magnetic resonance imaging (fMRI), many questions about the electrophysiological bases of resting-state alterations in psychiatric disorders, particularly among mood disorder patients, remain unanswered. Alongside important research using electroencephalography (EEG), the specific recent contributions and future promise of magnetoencephalography (MEG) in this field are not fully recognized and valued...
2017: Frontiers in Psychiatry
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