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https://www.readbyqxmd.com/read/28648295/detection-and-prevalence-of-protozoan-parasites-in-ready-to-eat-packaged-salads-on-sale-in-italy
#1
Tiziana Caradonna, Marianna Marangi, Federica Del Chierico, Nicola Ferrari, Sofia Reddel, Giorgia Bracaglia, Giovanni Normanno, Lorenza Putignani, Annunziata Giangaspero
To investigate the prevalence of protozoan contamination by Giardia duodenalis, Cryptosporidium spp., Toxoplasma gondii and Cyclospora cayetanensis, in 'ready to eat' (RTE) salads on sale in Italy, 648 packages were purchased from industrial and local brands. Nine individual packages from each brand were collected per month, pooled and subjected to microscopy and molecular analyses. Microscopic examination of 864 slides detected Cryptosporidium spp. but also Blastocystis hominis and Dientamoeba fragilis. Molecular tools identified G...
October 2017: Food Microbiology
https://www.readbyqxmd.com/read/28647137/apneic-oxygenation-reduces-the-incidence-of-hypoxemia-during-emergency-intubation-a-systematic-review-and-meta-analysis
#2
REVIEW
Ivan Pavlov, Sofia Medrano, Scott Weingart
STUDY OBJECTIVE: Apneic oxygenation has been advocated for the prevention of hypoxemia during emergency endotracheal intubation. Because of conflicting results from recent trials, the efficacy of apneic oxygenation remains unclear. We performed a systematic review and meta-analysis to investigate the effect of apneic oxygenation on the incidence of clinically significant hypoxemia during emergency endotracheal intubation. METHODS: MEDLINE, EMBASE, and PubMed databases were searched without language and time restrictions for studies of apneic oxygenation performed in a critical care setting...
June 15, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28622349/a-randomized-cross-over-study-of-the-acute-effects-of-running-5-km-on-glucose-insulin-metabolic-rate-cortisol-and-troponin-t
#3
Boris Keselman, Marta Vergara, Sofia Nyberg, Fredrik H Nystrom
BACKGROUND: We aimed to study the impact by running 5 km, at maximal speed, on the normal variations of metabolic variables related to glucose, insulin, insulin sensitivity, cortisol, glucagon, Troponin T and metabolic rate. MATERIAL AND METHODS: Five women and 12 men 25.7±5.2 years of age with a body-mass-index of 22.5±2.3 kg/m2 where recruited to run 5 km at individual maximal speed in the morning, and to a corresponding day of rest, followed by standardized breakfast and lunch meals...
2017: PloS One
https://www.readbyqxmd.com/read/28611940/involvement-of-chromatin-remodeling-genes-and-the-rho-gtpases-rhob-and-cdc42-in-ovarian-clear-cell-carcinoma
#4
Nicolai Skovbjerg Arildsen, Jenny-Maria Jönsson, Katarina Bartuma, Anna Ebbesson, Sofia Westbom-Fremer, Anna Måsbäck, Susanne Malander, Mef Nilbert, Ingrid A Hedenfalk
OBJECTIVE: Ovarian clear cell carcinomas (OCCCs) constitute a rare ovarian cancer subtype with distinct clinical features, but may nonetheless be difficult to distinguish morphologically from other subtypes. There is limited knowledge of genetic events driving OCCC tumorigenesis beyond ARID1A, which is reportedly mutated in 30-50% of OCCCs. We aimed to further characterize OCCCs by combined global transcriptional profiling and targeted deep sequencing of a panel of well-established cancer genes...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28608683/conformational-analysis-and-absolute-configuration-of-axially-chiral-1-aryl-and-1-3-bisaryl-xanthines
#5
Michele Mancinelli, Sofia Perticarari, Luca Prati, Andrea Mazzanti
The xanthine scaffold is known to be the forefather of a class of biological active molecules. Xanthine is a planar framework in which an aryl substituent linked in the 1 or 3 position is driven out of the xanthine plane because of the steric hindrance exerted by the two carbonyls. This work analyses the stereodynamics of some 1-aryl and 1,3-bisaryl-xanthines and describes the steric requirements needed to produce stable heteroaromatic atropisomers or diastereoisomers, with one or two N-Csp2 stereogenic axes...
June 22, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28604871/an-extended-%C3%AF-system-and-enhanced-electronic-delocalization-on-symmetric-ru3o-ch3coo-6-l-3-n-complexes-combined-with-azanaphthalene-ligands
#6
Bruna Possato, Victor M Deflon, Zeki Naal, André L B Formiga, Sofia Nikolaou
We report on the investigation of a new series of symmetric trinuclear ruthenium complexes combined with azanaphthalene ligands: [Ru3O(CH3COO)6(L)3]PF6 where L = (1) quinazoline (qui), (2) 5-nitroisoquinoline (5-nitroiq), (3) 5-bromoisoquinoline (5-briq), (4) isoquinoline (iq), (5) 5-aminoisoquinoline (5-amiq), and (6) 5,6,7,8-tetrahydroisoquinoline (thiq). The crystal structure of complex 1, [Ru3O(CH3COO)6(qui)3]PF6, was determined by X-ray diffraction analysis, showing a high degree of co-planarity between the [Ru3O] plane and the azanaphthalene ligands...
June 12, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28602163/investigation-of-a-food-borne-outbreak-of-gastroenteritis-in-a-school-canteen-revealed-a-variant-of-sapovirus-genogroup-v-not-detected-by-standard-pcr-sollentuna-sweden-2016
#7
Maria-Pia Hergens, Joanna Nederby Öhd, Erik Alm, Helena H Askling, Sofia Helgesson, Mona Insulander, Nina Lagerqvist, Bo Svenungsson, Malin Tihane, Thomas Tolfvenstam, Per Follin
A food-borne outbreak of gastroenteritis with more than 650 suspected cases occurred in April 2016 in Sollentuna, Sweden. It originated in a school kitchen serving a total of 2,700 meals daily. Initial microbiological testing (for Campylobacter, Salmonella, Shigella, Yersinia, Giardia, Cryptosporidium, Entamoeba histolytica, adeno-, astro-, noro-, rota- and sapovirus) of stool samples from 15 symptomatic cases was negative, despite a clinical presentation suggestive of calicivirus. Analyses of the findings from both the Sollentuna municipality environmental team and a web-based questionnaire suggested that the source of the outbreak was the salad buffet served on 20 April, although no specific food item could be identified...
June 1, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28591034/surgical-performance-of-large-loop-excision-of-the-transformation-zone-in-a-training-model-a-prospective-cohort-study
#8
Günther A Rezniczek, Sofia Severin, Ziad Hilal, Askin Dogan, Harald Krentel, Bernd Buerkle, Clemens B Tempfer
Large loop excision of the transformation zone (LLETZ) is one of the most common procedures in operative gynecology and it is a routine part of the surgical training program of residents. There is, however, no established and standardized method of teaching residents how to perform LLETZ. Here, we present a surgical training model and assessed the improvement of surgical skills during repeated hands-on trainings of LLETZ in this model.Surgical novices and experts were recruited and were shown a LLETZ training video and then performed 3 LLETZ training sessions on consecutive days...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28569212/the-prevalence-of-acpa-is-lower-in-rheumatoid-arthritis-patients-with-an-older-age-of-onset-but-the-composition-of-the-acpa-response-appears-identical
#9
Debbie M Boeters, Lukas Mangnus, Sofia Ajeganova, Elisabet Lindqvist, Björn Svensson, René E M Toes, Leendert A Trouw, Tom W J Huizinga, Francis Berenbaum, Jacques Morel, Solbritt Rantapää-Dahlqvist, Annette H M van der Helm-van Mil
BACKGROUND: Rheumatoid arthritis (RA) consists of two syndromes, one autoantibody-positive and one autoantibody-negative. Existing data on the relation between age of onset and prevalence of autoantibodies were conflicting. Therefore this multicohort study assessed the age of onset in relation to the presence of autoantibodies. The association with characteristics of the anti-citrullinated protein antibodies (ACPA) response was also explored. METHODS: The 1987 criteria-positive RA patients included in the Leiden EAC, BARFOT, ESPOIR, Umeå and Lund cohorts (n = 3321) were studied at presentation for age of onset and the presence of ACPA, rheumatoid factor (RF) and anti-carbamylated protein (anti-CarP) antibodies...
May 31, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28567579/left-atrial-appendage-volume-as-a-new-predictor-of-atrial-fibrillation-recurrence-after-catheter-ablation
#10
Pedro Pinto Teixeira, Mário Martins Oliveira, Ruben Ramos, Pedro Rio, Pedro Silva Cunha, Ana Sofia Delgado, Ricardo Pimenta, Rui Cruz Ferreira
PURPOSE: Recurrence of atrial fibrillation (AF) after catheter ablation is common, being clinically relevant to identify predictors of recurrence. The left atrial appendage (LAA) role as an AF trigger is scarcely explored. Our aim was to identify if LAA volume is an independent predictor of AF recurrence after catheter ablation. METHODS: We analysed 52 patients (aged 54 ± 10 years, 58% male) with paroxysmal and persistent AF who underwent a first AF catheter ablation and had performed contrast-enhanced cardiac computed tomography (CT) prior to the procedure...
May 31, 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28555557/-psychological-treatments-for-borderline-personality-disorder-a-review-of-cognitive-behavioral-oriented-therapies
#11
REVIEW
Sofia Marques, Daniel Barrocas, Daniel Rijo
INTRODUCTION: Borderline personality disorder is the most common personality disorder, with a global prevalence rate between 1.6% and 6%. It is characterized by affective disturbance and impulsivity, which lead to a high number of self-harm behaviors and great amount of health services use. International guidelines recommend psychotherapy as the primary treatment for borderline personality disorder. This paper reviews evidence about the effects and efficacy of cognitive-behavioral oriented psychological treatments for borderline personality disorder...
April 28, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28527093/income-disparities-in-healthcare-use-remain-after-controlling-for-healthcare-need-evidence-from-swedish-register-data-on-psoriasis-and-psoriatic-arthritis
#12
Sofia Löfvendahl, Anna Jöud, Ingemar F Petersson, Elke Theander, Åke Svensson, Katarina Steen Carlsson
We used a southern Swedish cohort of psoriasis (PSO) and psoriatic arthritis (PsA) patients and population-based referents (N = 57,800) to investigate the influence of socioeconomic and demographic factors on the probability of healthcare use and on healthcare costs when controlling for need as measured by PSO/PsA and common additional morbidities such as diabetes, depression and myocardial infarction. People with PSO/PsA were identified by ICD-10 codes in the Skåne Healthcare Register 1998-2007. Resource use and costs for years 2008-2011 were retrieved from the Skåne Healthcare Register and the Swedish Prescribed Drug Register, and socioeconomic data were retrieved from Statistics Sweden...
May 19, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28515210/impact-of-perceived-control-on-all-cause-and-cardiovascular-disease-mortality-in-three-urban-populations-of-central-and-eastern-europe-the-hapiee-study
#13
Magdalena Kozela, Andrzej Pająk, Agnieszka Micek, Agnieszka Besala, Ruzena Kubinova, Sofia Malyutina, Abdonas Tamosiunas, Hynek Pikhart, Anne Peasey, Yuri Nikitin, Michael Marmot, Martin Bobak
BACKGROUND: Inverse associations between perceived control and cardiovascular disease (CVD) have been reported in studies from Western Europe and the USA. To assess this relationship across different populations, we investigated the association between perceived control and all-cause and CVD mortality in three population-based cohorts of Eastern European countries. METHODS: We analysed data from a prospective cohort study in random population samples in Krakow (Poland), Novosibirsk (Russia) and six Czech towns...
May 17, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28500616/significance-of-blood-neutrophil-to-lymphocyte-ratio-for-prognostic-stratification-of-patients-with-gastroesophageal-junction-adenocarcinoma-in-the-era-of-the-8th-edition-of-the-american-joint-committee-on-cancer-ajcc8-staging
#14
Alicia-Marie Conway, Zena Salih, George Papaxoinis, Kimberly Fletcher, Jamie Weaver, Ana Patrao, Robert Noble, Sofia Stamatopoulou, Vikki Owen-Holt, Wasat Mansoor
The prognosis of patients with gastroesophageal junction (GOJ) adenocarcinoma depends mainly on the clinical staging, as described by the new AJCC8 (American Joint Committee on Cancer 8th edition). Evidence suggests that peripheral blood neutrophil-to-lymphocyte ratio (NLR) may be of prognostic significance in patients with upper gastrointestinal cancers. We examined the prognostic significance of NLR in the era of the new AJCC8 staging system. In this single-centre cohort study, retrospective data on patients with operable GOJ adenocarcinoma treated with perioperative chemotherapy were analysed...
June 2017: Medical Oncology
https://www.readbyqxmd.com/read/28480012/exploring-the-impact-of-multidecadal-environmental-changes-on-the-population-genetic-structure-of-a-marine-primary-producer
#15
Nina Lundholm, Sofia Ribeiro, Anna Godhe, Lene Rostgaard Nielsen, Marianne Ellegaard
Many marine protists form resting stages that can remain viable in coastal sediments for several decades. Their long-term survival offers the possibility to explore the impact of changes in environmental conditions on population dynamics over multidecadal time scales. Resting stages of the phototrophic dinoflagellate Pentapharsodinium dalei were isolated and germinated from five layers in dated sediment cores from Koljö fjord, Sweden, spanning ca. 1910-2006. This fjord has, during the last century, experienced environmental fluctuations linked to hydrographic variability mainly driven by the North Atlantic Oscillation...
May 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28479971/reliability-validity-and-psychometric-properties-of-the-greek-translation-of-the-posttraumatic-stress-disorder-scale
#16
Konstantinos Kontoangelos, Sofia Tsiori, Garyfalia Poulakou, Konstantinos Protopapas, Ioannis Katsarolis, Vissaria Sakka, Dimitra Kavatha, Antonios Papadopoulos, Anastasia Antoniadou, Charalambos C Papageorgiou
The Greek version of the Davidson Trauma Scale (DTS) was developed to respond to the need of Greek-speaking individuals. The translated questionnaire was administered to 128 HIV outpatients (aged 37.1±9.1) and 166 control patients (aged 32.4±13.4). In addition to the DTS Greek scale, subjects were assessed with two other scales useful for assessing validity. For each factor analyses two components were extracted, based on Cattell's scree test. The two components solution accounted for 55.34% of the total variation in case of frequency variables and 61...
March 22, 2017: Mental Illness
https://www.readbyqxmd.com/read/28478701/exercise-habits-and-factors-associated-with-exercise-in-systemic-sclerosis-a-scleroderma-patient-centered-intervention-network-spin-cohort-study
#17
Marleine Azar, Danielle B Rice, Linda Kwakkenbos, Marie-Eve Carrier, Ian Shrier, Susan J Bartlett, Marie Hudson, Luc Mouthon, Serge Poiraudeau, Cornelia H M van den Ende, Sindhu R Johnson, Tatiana Sofia Rodriguez Reyna, Anne A Schouffoer, Joep Welling, Brett D Thombs
OBJECTIVE: Exercise is associated with improved health in many medical conditions. Little is known about the exercise habits of people with systemic sclerosis (SSc, or scleroderma). This study assessed the proportion of individuals with SSc who exercise and associations of demographic and disease variables with exercise. Additionally, the weekly amount of time spent exercising and the types of exercise performed were assessed among patients exercising. METHODS: The sample consisted of adult participants with SSc enrolled in the Scleroderma Patient-centered Intervention Network (SPIN) Cohort who completed baseline questionnaires from March 2014 through August 2015...
May 8, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28474340/doddering-but-dear-%C3%A2-even-in-the-eyes-of-young-children-age-stereotyping-and-prejudice-in-childhood-and-adolescence
#18
Christin-Melanie Vauclair, Ricardo Borges Rodrigues, Sibila Marques, Carla Sofia Esteves, Filipa Cunha, Filomena Gerardo
This study aims to explore age prejudice, and to examine age stereotyping in children and adolescents by adopting the Stereotype Content Model (SCM) as a theoretical framework. It was hypothesised that children are socialised into adopting an ambivalent representation of old age (socialisation hypothesis) and that this cognitive bias becomes weaker in adolescence due to greater cognitive maturity (developmental hypothesis). By analysing representative data from Portugal (European Social Survey; N = 2367), it was ascertained that the ambivalent age stereotype (higher evaluations of warmth than competence for older people) is indeed a shared social representation of older people in Portuguese society...
May 5, 2017: International Journal of Psychology: Journal International de Psychologie
https://www.readbyqxmd.com/read/28472138/ecological-value-of-macrophyte-cover-in-creating-habitat-for-microalgae-diatoms-and-zooplankton-rotifers-and-crustaceans-in-small-field-and-forest-water-bodies
#19
Sofia Celewicz-Gołdyn, Natalia Kuczyńska-Kippen
Due to their small area and shallow depth ponds are usually treated as a single sampling unit, while various microhabitats offer different environmental conditions. Thus, we tested the effect of different habitat types typically found within small ponds on the microalgae and zooplankton communities. We found that submerged macrophytes have the strongest impact on microalgae and zooplankton communities out of all the analysed habitats. Some epontic diatoms (e.g. Fragilaria dilatata, Cymbella affinis) and littoral-associated zooplankton species (e...
2017: PloS One
https://www.readbyqxmd.com/read/28453780/variation-in-maturity-onset-diabetes-of-the-young-genes-influence-response-to-interventions-for-diabetes-prevention
#20
Liana K Billings, Kathleen A Jablonski, A Sofia Warner, Yu-Chien Cheng, Jarred B McAteer, Laura Tipton, Alan R Shuldiner, David A Ehrmann, Alisa K Manning, Dana Dabelea, Paul W Franks, Steven E Kahn, Toni I Pollin, William C Knowler, David Altshuler, Jose C Florez
CONTEXT: Variation in genes that cause Maturity-Onset Diabetes of the Young (MODY) has been associated with diabetes incidence and glycemic traits. OBJECTIVES: This study aimed to determine whether genetic variation in MODY genes leads to differential responses to insulin-sensitizing interventions. DESIGN AND SETTING: This was a secondary analysis of a multicenter randomized clinical trial, the Diabetes Prevention Program (DPP), involving 27 U...
April 27, 2017: Journal of Clinical Endocrinology and Metabolism
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