keyword
MENU ▼
Read by QxMD icon Read
search

Sofia analyser

keyword
https://www.readbyqxmd.com/read/29161798/intrapartum-care-quality-indicators-a-literature-review
#1
Elisa Lazzaretto, Antonella Nespoli, Simona Fumagalli, Elisabetta Colciago, Sofia Perego, Anna Locatelli
BACKGROUND: Quality of care is increasingly recognized as a critical aspect of the maternal and newborn health, mainly with respect to care around labour and delivery and in the immediate postnatal period. The Aim of this Review is to identify the recommended intrapartum care indicators in order to measure the quality of Midwifery care. METHODS: A structured literature search was conducted in August 2017 incorporating English and Italian language studies from 1993 and onwards to identify published articles on quality standards of intrapartum care...
November 21, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29158416/tracking-the-genome-wide-outcomes-of-a-transposable-element-burst-over-decades-of-amplification
#2
Lu Lu, Jinfeng Chen, Sofia M C Robb, Yutaka Okumoto, Jason E Stajich, Susan R Wessler
To understand the success strategies of transposable elements (TEs) that attain high copy numbers, we analyzed two pairs of rice (Oryza sativa) strains, EG4/HEG4 and A119/A123, undergoing decades of rapid amplification (bursts) of the class 2 autonomous Ping element and the nonautonomous miniature inverted repeat transposable element (MITE) mPing Comparative analyses of whole-genome sequences of the two strain pairs validated that each pair has been maintained for decades as inbreds since divergence from their respective last common ancestor...
November 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29157004/vanadium-inhalation-induces-retinal-m%C3%A3-ller-glial-cell-mgc-alterations-in-a-murine-model
#3
Silvana Cervantes-Yépez, Lorena Sofía López-Zepeda, Teresa Fortoul
BACKGROUND: Vanadium (V) is a transition metal adhered to suspended particles. Previous studies demonstrated that V inhalation causes oxidative stress in the ependymal epithelium, the choroid plexus on brain lateral ventricles and in the retina. Inhaled-V reaches the eye´s retina through the systemic circulation; however, its effect on the retina has not been widely studied. The Müller glial cell provides support and structure to the retina, facilitates synapses and regulates the microenvironment and neuronal metabolism...
November 20, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29149092/analysis-of-the-roles-of-the-arabidopsis-nmat2-and-pmh2-proteins-provided-with-new-insights-into-the-regulation-of-group-ii-intron-splicing-in-land-plant-mitochondria
#4
Michal Zmudjak, Sofia Shevtsov, Laure D Sultan, Ido Keren, Oren Ostersetzer-Biran
Plant mitochondria are remarkable with respect to the presence of numerous group II introns which reside in many essential genes. The removal of the organellar introns from the coding genes they interrupt is essential for respiratory functions, and is facilitated by different enzymes that belong to a diverse set of protein families. These include maturases and RNA helicases related proteins that function in group II intron splicing in different organisms. Previous studies indicate a role for the nMAT2 maturase and the RNA helicase PMH2 in the maturation of different pre-RNAs in Arabidopsis mitochondria...
November 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29147604/tap1-down-regulation-elicits-immune-escape-and-poor-prognosis-in-colorectal-cancer
#5
Agnes Ling, Anna Löfgren-Burström, Pär Larsson, Xingru Li, Maria L Wikberg, Åke Öberg, Roger Stenling, Sofia Edin, Richard Palmqvist
The anti-tumor immune response has been shown to be of great prognostic importance in colorectal cancer (CRC) and so has the tumors ability for immune evasion. Our aim of this study was to investigate tumor factors that influence immunity. We used a gene expression array to search for potential mechanisms of tumor immune escape. One candidate gene identified was TAP1, involved in antigen presentation by MHC class I. TAP1 protein expression was evaluated by immunohistochemistry in 436 CRC patients of the Colorectal Cancer in Umeå Study cohort...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/29146654/diagnostic-and-laboratory-test-ordering-in-northern-portuguese-primary-health-care-a-cross-sectional-study
#6
Luísa Sá, Andreia Sofia Costa Teixeira, Fernando Tavares, Cristina Costa-Santos, Luciana Couto, Altamiro Costa-Pereira, Alberto Pinto Hespanhol, Paulo Santos, Carlos Martins
OBJECTIVES: To characterise the test ordering pattern in Northern Portugal and to investigate the influence of context-related factors, analysing the test ordered at the level of geographical groups of family physicians and at the level of different healthcare organisations. DESIGN: Cross-sectional study. SETTING: Northern Primary Health Care, Portugal. PARTICIPANTS: Records about diagnostic and laboratory tests ordered from 2035 family physicians working at the Northern Regional Health Administration, who served approximately 3...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29134724/biogeography-of-mutualistic-fungi-cultivated-by-leafcutter-ants
#7
Ulrich G Mueller, Heather D Ishak, Sofia M Bruschi, Chad C Smith, Jacob J Herman, Scott E Solomon, Alexander S Mikheyev, Christian Rabeling, Jarrod J Scott, Michael Cooper, Andre Rodrigues, Adriana Ortiz, Carlos Roberto F Brandão, John E Lattke, Fernando C Pagnocca, Stephen A Rehner, Ted R Schultz, Heraldo L Vasconcelos, Rachelle M M Adams, Martin Bollazzi, Rebecca M Clark, Anna G Himler, John S LaPolla, Inara R Leal, Robert A Johnson, Flavio Roces, Jeffrey Sosa-Calvo, Rainer Wirth, Maurício Bacci
Leafcutter ants propagate co-evolving fungi for food. The nearly 50 species of leafcutter ants (Atta, Acromyrmex) range from Argentina to the USA, with the greatest species diversity in southern South America. We elucidate the biogeography of fungi cultivated by leafcutter ants using DNA-sequence and microsatellite-marker analyses of 474 cultivars collected across the leafcutter range. Fungal cultivars belong to two clades (Clade-A, Clade-B). The dominant and widespread Clade-A cultivars form three genotype-clusters, with their relative prevalence corresponding to southern South America, northern South America, and Central & North America...
November 13, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/29134487/sildenafil-citrate-use-in-addis-ababa-characteristics-of-users-and-pharmacists-dispensing-practices
#8
Dawit Teshome Gebregeorgise, Yajeb Melesse Belay, Sofia Kälvemark Sporrong
Background Studies have reported misuse of sildenafil citrate for recreational purpose, not least by healthy young men. This is becoming a major concern, for medical and other reasons. Objective The aim of this study was to document the characteristics of sildenafil citrate users and to explore the dispensing practices of the medicine in selected community pharmacies in Addis Ababa, Ethiopia. Setting Data was collected in community pharmacies in Addis Ababa, Ethiopia. Method A survey, using a self-administrated questionnaire, was conducted among customers who purchased sildenafil citrate from community pharmacies...
November 14, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29132006/ocean-acidification-dampens-physiological-stress-response-to-warming-and-contamination-in-a-commercially-important-fish-argyrosomus-regius
#9
Eduardo Sampaio, Ana R Lopes, Sofia Francisco, Jose R Paula, Marta Pimentel, Ana L Maulvault, Tiago Repolho, Tiago F Grilo, Pedro Pousão-Ferreira, António Marques, Rui Rosa
Increases in carbon dioxide (CO2) and other greenhouse gases emissions are changing ocean temperature and carbonate chemistry (warming and acidification, respectively). Moreover, the simultaneous occurrence of highly toxic and persistent contaminants, such as methylmercury, will play a key role in further shaping the ecophysiology of marine organisms. Despite recent studies reporting mostly additive interactions between contaminant and climate change effects, the consequences of multi-stressor exposure are still largely unknown...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29126275/active-antimicrobial-efflux-in-staphylococcus-epidermidis-building-up-of-resistance-to-fluoroquinolones-and-biocides-in-a-major-opportunistic-pathogen
#10
Sofia Santos Costa, Miguel Viveiros, Constança Pomba, Isabel Couto
Objectives: To analyse the efflux-mediated response of Staphylococcus epidermidis to ethidium bromide (EtBr), a substrate of multidrug efflux pumps (EPs). Methods: The susceptible reference strain S. epidermidis ATCC 12228 was exposed to a step-wise adaptation to EtBr. The resulting EtBr-adapted strains were characterized regarding their antibiotic and biocide susceptibility by MIC determination and evaluation of efflux activity by re-determination of MICs in the presence of known efflux inhibitors and real-time fluorometry...
November 8, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29121255/adipocyte-expression-of-slc19a1-links-dna-hypermethylation-to-adipose-tissue-inflammation-and-insulin-resistance
#11
Paul Petrus, Lucia Bialesova, Antonio Checa, Alastair Kerr, Shama Naz, Jesper Bäckdahl, Ana Gracia, Sofia Toft, Karin Dahlman-Wright, Per Hedén, Ingrid Dahlman, Craig E Wheelock, Peter Arner, Niklas Mejhert, Hui Gao, Mikael Rydén
Context: Insulin resistance (IR) is promoted by a chronic low-grade inflammation in white adipose tissue (WAT). The latter may be regulated through epigenetic mechanisms such as DNA-methylation. The one carbon cycle (1CC) is a central metabolic process governing DNA-methylation. Objective: To identify adipocyte-expressed 1CC genes linked to WAT inflammation, IR and their causal role. Design: Cohort study. Setting: Outpatient academic clinic...
November 7, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29118433/visualization-of-lipid-directed-dynamics-of-perilipin-1-in-human-primary-adipocytes
#12
Jesper S Hansen, Sofia de Maré, Helena A Jones, Olga Göransson, Karin Lindkvist-Petersson
Perilipin 1 is a lipid droplet coating protein known to regulate lipid metabolism in adipocytes by serving as a physical barrier as well as a recruitment site for lipases to the lipid droplet. Phosphorylation of perilipin 1 by protein kinase A rapidly initiates lipolysis, but the detailed mechanism on how perilipin 1 controls lipolysis is unknown. Here, we identify specific lipid binding properties of perilipin 1 that regulate the dynamics of lipolysis in human primary adipocytes. Cellular imaging combined with biochemical and biophysical analyses demonstrate that perilipin 1 specifically binds to cholesteryl esters, and that their dynamic properties direct segregation of perilipin 1 into topologically distinct micro domains on the lipid droplet...
November 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29101427/sociodemographic-patterns-in-pharmacy-dispensing-of-medications-for-erectile-dysfunction-in-sweden
#13
Pernilla J Bjerkeli, Shai Mulinari, Sofia Zettermark, Juan Merlo
PURPOSE: The purpose of this study is to investigate the relationship between sociodemographic factors and pharmacy dispensing of medications for erectile dysfunction (ED) in the general population of middle-aged and elderly men. By considering a number of medical conditions that could promote or contraindicate use of ED medication, the analysis could help capture prescription patterns that might not be explained by medical needs. METHODS: Individual-level pharmacy dispensing data from 2006 for a population-based cohort of 216,148 men aged 45-79 years in the county Scania, Sweden, were analysed...
November 3, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29100657/cellular-ultrastructural-and-molecular-analyses-of-epidermal-cell-development-in-the-planarian-schmidtea-mediterranea
#14
Li-Chun Cheng, Kimberly C Tu, Chris W Seidel, Sofia M C Robb, Fengli Guo, Alejandro Sánchez Alvarado
The epidermis is essential for animal survival, providing both a protective barrier and cellular sensor to external environments. The generally conserved embryonic origin of the epidermis, but the broad morphological and functional diversity of this organ across animals is puzzling. We define the transcriptional regulators underlying epidermal lineage differentiation in the planarian Schmidtea mediterranea, an invertebrate organism that, unlike fruitflies and nematodes, continuously replaces its epidermal cells...
September 11, 2017: Developmental Biology
https://www.readbyqxmd.com/read/29097431/a-simple-algorithm-for-the-identification-of-clinical-copd-phenotypes
#15
Pierre-Régis Burgel, Jean-Louis Paillasseur, Wim Janssens, Jacques Piquet, Gerben Ter Riet, Judith Garcia-Aymerich, Borja Cosio, Per Bakke, Milo A Puhan, Arnulf Langhammer, Inmaculada Alfageme, Pere Almagro, Julio Ancochea, Bartolome R Celli, Ciro Casanova, Juan P de-Torres, Marc Decramer, Andrés Echazarreta, Cristobal Esteban, Rosa Mar Gomez Punter, MeiLan K Han, Ane Johannessen, Bernhard Kaiser, Bernd Lamprecht, Peter Lange, Linda Leivseth, Jose M Marin, Francis Martin, Pablo Martinez-Camblor, Marc Miravitlles, Toru Oga, Ana Sofia Ramírez, Don D Sin, Patricia Sobradillo, Juan J Soler-Cataluña, Alice M Turner, Francisco Javier Verdu Rivera, Joan B Soriano, Nicolas Roche
This study aimed to identify simple rules for allocating chronic obstructive pulmonary disease (COPD) patients to clinical phenotypes identified by cluster analyses.Data from 2409 COPD patients of French/Belgian COPD cohorts were analysed using cluster analysis resulting in the identification of subgroups, for which clinical relevance was determined by comparing 3-year all-cause mortality. Classification and regression trees (CARTs) were used to develop an algorithm for allocating patients to these subgroups...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29089044/association-between-serum-25-hidroxyvitamin-d-concentrations-and-ultraviolet-index-in-portuguese-older-adults-a-cross-sectional-study
#16
Sofia Cardoso, Alejandro Santos, Rita S Guerra, Ana S Sousa, Patrícia Padrão, Pedro Moreira, Cláudia Afonso, Teresa F Amaral, Nuno Borges
BACKGROUND: The older population is a risk group for hypovitaminosis D. The Ultraviolet Index (UVI) can be an indicator of potential for cutaneous synthesis of vitamin D but physiological and other environmental factors also influence vitamin D synthesis and status. Knowledge about vitamin D status in Portuguese older adults is limited. This study aims to explore the association between Ultraviolet Index and serum 25-hidroxyvitamin D3 [25(OH)D] levels accounting for other potential influential factors...
October 31, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29078011/bone-mineral-density-in-familial-partial-lipodystrophy
#17
Antía Fernández-Pombo, Javier A Ossandon-Otero, Cristina Guillín-Amarelle, Sofía Sánchez-Iglesias, Ana I Castro, Blanca González-Méndez, Silvia Rodríguez-García, Leticia Rodriguez-Cañete, Felipe F Casanueva, David Araújo-Vilar
OBJECTIVE: Type 1 and type 2 familial partial lipodystrophies (FPLD) are characterized by the loss or increase of subcutaneous fat in certain body regions, as well as metabolic disorders. Higher muscle volume and mass have also been described. However, so far, possible bone involvement has not been studied. The aim of this study was to evaluate bone mineral density (BMD) in patients with type 1 and type 2 FPLD. METHODS: A total of 143 women were selected and distributed into three groups (17 women with FPLD2, 82 women with FPLD1 and 44 non-lipodystrophic obese female controls)...
October 27, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29048212/living-too-long-exploring-attitudes-toward-reaching-100-years-old
#18
Oscar Ribeiro, Sofia Canedo, Margarida Cerqueira, Ana Nascimento, Laetitia Teixeira
Objective This study analyses the relationship between pro- and anti-longevity attitudes, attitudes toward centenarians, and the wish to reach 100 years of age in a sample of community dwelling older adults. Methods Participants ( N = 137) completed a questionnaire on attitudes toward life-extension and an aging semantic differential using centenarians as an attitudinal target. Sociodemographic information, perceived health status, and information on knowing a centenarian were also obtained. A cluster analysis was used to identify subgroups (leaning anti-longevity group vs...
January 1, 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/29045943/reference-ranges-for-fetal-atrioventricular-and-ventriculoatrial-time-intervals-and-their-ratios-during-normal-pregnancy
#19
Beatrice Mosimann, Georgios Arampatzis, Sofia Amylidi-Mohr, Anice Bessire, Marialuigia Spinelli, Petros Koumoutsakos, Daniel Surbek, Luigi Raio
BACKGROUND: The diagnostic assessment of fetal arrhythmias relies on the measurements of atrioventricular (AV) and ventriculoatrial (VA) time intervals. Pulsed Doppler over in- and outflow of the left ventricle and tissue Doppler imaging are well-described methods, while Doppler measurements between the left brachiocephalic vein and the aortic arch are less investigated. The aim of this study was to compare these methods of measurement, to find influencing factors on AV and VA times and their ratio, and to create reference ranges...
October 19, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29032145/genetic-association-analysis-of-vitamin-d-receptor-gene-polymorphisms-and-obesity-related-phenotypes
#20
Correa-Rodríguez María, Jose Antonio Carrillo-Ávila, Schmidt-RioValle Jacqueline, González-Jiménez Emilio, Vargas Sofia, Martin Javier, Rueda-Medina Blanca
Vitamin D has been established as a key factor in the development of obesity through the vitamin D receptor (VDR). The aim of this study was to investigate the contribution of the VDR gene to obesity-related phenotypes in a population of Caucasian young adults. The study population consisted of 701 healthy Spanish young adults (mean age 20.41±2.48). Three single-nucleotide polymorphisms (SNPs) of VDR (TaqI, BsmI and FokI) were selected as genetic markers. Body composition measurements including weight, body mass index (BMI), fat mass (FM), percentage of fat mass (PFM), fat-free mass (FFM) and visceral fat level (VFL) were analysed...
January 15, 2018: Gene
keyword
keyword
110482
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"