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https://www.readbyqxmd.com/read/28207386/detection-and-compensation-of-periodic-motion-in-magnetic-particle-imaging
#1
Nadine Gdaniec, Matthias Schluter, Martin Hofmann, Michael Kaul, Kannan Krishnan, Alexander Schlafer, Tobias Knopp
The temporal resolution of the tomographic imaging method magnetic particle imaging (MPI) is remarkably high. The spatial resolution is degraded for measured voltage signal with low signal-to-noise ratio, because the regularization in the image reconstruction step needs to be increased for system-matrix approaches and for deconvolution steps in x-space approaches. To improve the signal-to-noise ratio, block-wise averaging of the signal over time can be advantageous. However, since block-wise averaging decreases the temporal resolution, it prevents resolving the motion...
February 9, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28188229/the-human-long-interspersed-element-1-retrotransposon-an-emerging-biomarker-of-neoplasia
#2
REVIEW
Daniel Ardeljan, Martin S Taylor, David T Ting, Kathleen H Burns
BACKGROUND: A large portion of intronic and intergenic space in our genome consists of repeated sequences. One of the most prevalent is the long interspersed element-1 (LINE-1, L1) mobile DNA. LINE-1 is rightly receiving increasing interest as a cancer biomarker. CONTENT: Intact LINE-1 elements are self-propagating. They code for RNA and proteins that function to make more copies of the genomic element. Our current understanding is that this process is repressed in most normal cells, but that LINE-1 expression is a hallmark of many types of malignancy...
February 10, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28187674/a-new-species-of-poison-dart-frog-anura-dendrobatidae-from-manu-province-amazon-region-of-southeastern-peru-with-notes-on-its-natural-history-bioacoustics-phylogenetics-and-recommended-conservation-status
#3
Shirley J Serrano-Rojas, Andrew Whitworth, Jaime Villacampa, Rudolf VON May, Roberto C Gutiérrez, José M Padial, Juan C Chaparro
We describe and name a new species of poison-dart frog from the Amazonian slopes of the Andes in Manu Province, Madre de Dios Department, Peru; specifically within the Amarakaeri Communal Reserve and the buffer zone of Manu National Park. Ameerega shihuemoy sp. nov. is supported by a unique combination of characters: black dorsum with cream to light orange dorsolateral lines, blue belly reticulated with black, and the lack of axillary, thigh and calf flash marks. Within Ameerega, it shares the general appearance of A...
January 16, 2017: Zootaxa
https://www.readbyqxmd.com/read/28186148/measurement-of-absolute-frequency-of-continuous-wave-terahertz-radiation-in-real-time-using-a-free-running-dual-wavelength-mode-locked-erbium-doped-fibre-laser
#4
Guoqing Hu, Tatsuya Mizuguchi, Xin Zhao, Takeo Minamikawa, Takahiko Mizuno, Yuli Yang, Cui Li, Ming Bai, Zheng Zheng, Takeshi Yasui
A single, free-running, dual-wavelength mode-locked, erbium-doped fibre laser was exploited to measure the absolute frequency of continuous-wave terahertz (CW-THz) radiation in real time using dual THz combs of photo-carriers (dual PC-THz combs). Two independent mode-locked laser beams with different wavelengths and different repetition frequencies were generated from this laser and were used to generate dual PC-THz combs having different frequency spacings in photoconductive antennae. Based on the dual PC-THz combs, the absolute frequency of CW-THz radiation was determined with a relative precision of 1...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28173929/postflight-reconditioning-for-european-astronauts-a-case-report-of-recovery-after-six-months-in-space
#5
Nora Petersen, Gunda Lambrecht, Jonathan Scott, Natalie Hirsch, Maria Stokes, Joachim Mester
BACKGROUND: Postflight reconditioning of astronauts is understudied. Despite a rigorous, daily inflight exercise countermeasures programme during six months in microgravity (μG) on-board the International Space Station (ISS), physiological impairments occur and postflight reconditioning is still required on return to Earth. Such postflight programmes are implemented by space agency reconditioning specialists. Case Description and Assessments: A 38 year old male European Space Agency (ESA) crewmember's pre- and postflight (at six and 21 days after landing) physical performance from a six-month mission to ISS are described...
January 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28157936/langley-mobile-ozone-lidar-ozone-and-aerosol-atmospheric-profiling-for-air-quality-research
#6
Russell De Young, William Carrion, Rene Ganoe, Denis Pliutau, Guillaume Gronoff, Timothy Berkoff, Shi Kuang
The Langley mobile ozone lidar (LMOL) is a mobile ground-based ozone lidar system that consists of a pulsed UV laser producing two UV wavelengths of 286 and 291 nm with energy of approximately 0.2  mJ/pulse and repetition rate of 1 kHz. The 527 nm pump laser is also transmitted for aerosol measurements. The receiver consists of a 40 cm parabolic telescope, which is used for both backscattered analog and photon counting. The lidar is very compact and highly mobile. This demonstrates the utility of very small lidar systems eventually leading to space-based ozone lidars...
January 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28134023/effects-of-ionizing-radiation-on-dna-methylation-from-experimental-biology-to-clinical-applications
#7
Isabelle R Miousse, Kristy R Kutanzi, Igor Koturbash
PURPOSE: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) radiation, is being widely utilized in medicine, as well as in multiple industrial applications. Additionally, an interest in understanding the effects of high-LET irradiation is emerging due to the potential of exposure during space missions and the growing utilization of LET radiation in medicine. CONCLUSIONS: In this review, we summarize the current knowledge of the effects of IR on DNA methylation, a key epigenetic mechanism regulating the expression of genetic information...
January 30, 2017: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/28131397/multi-loop-control-of-ups-inverter-with-a-plug-in-odd-harmonic-repetitive-controller
#8
Reza Razi, Mohammad-Sadegh Karbasforooshan, Mohammad Monfared
This paper proposes an improved multi-loop control scheme for the single-phase uninterruptible power supply (UPS) inverter by using a plug-in odd-harmonic repetitive controller to regulate the output voltage. In the suggested control method, the output voltage and the filter capacitor current are used as the outer and inner loop feedback signals, respectively and the instantaneous value of the reference voltage feedforwarded to the output of the controller. Instead of conventional linear (proportional-integral/-resonant) and conventional repetitive controllers, a plug-in odd-harmonic repetitive controller is employed in the outer loop to regulate the output voltage, which occupies less memory space and offers faster tracking performance compared to the conventional one...
January 25, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28129063/power-and-phase-of-alpha-oscillations-reveal-an-interaction-between-spatial-and-temporal-visual-attention
#9
Sayeed A D Kizuk, Kyle E Mathewson
Oscillatory brain rhythms can bias attention via phase and amplitude changes, which modulate sensory activity, biasing information to be processed or ignored. Alpha band (7-14 Hz) oscillations lateralize with spatial attention and rhythmically inhibit visual activity and awareness through pulses of inhibition. Here we show that human observers' awareness of spatially unattended targets is dependent on both alpha power and alpha phase at target onset. Following a predictive directional cue, alpha oscillations were entrained bilaterally using repetitive visual stimuli...
October 19, 2016: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28114025/ventral-tegmental-area-dopamine-neurons-firing-model-reveals-prenatal-nicotine-induced-alterations
#10
Andrei Dragomir, Yasemin M Akay, Die Zhang, Metin Akay
The dopamine (DA) neurons found in the Ventral Tegmental Area (VTA) are widely involved in the addiction and natural reward circuitry of the brain. Their firing patterns were shown to be important modulators of dopamine release and repetitive burst-like firing activity was highlighted as a major firing pattern of DA neurons in the VTA. In the present study we use a state space model to characterize the DA neurons firing patterns, and trace transitions of neural activity through bursting and non-bursting states...
December 6, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28113578/2d-versus-3d-cross-correlation-based-radial-and-circumferential-strain-estimation-using-multiplane-2d-ultrafast-ultrasound-in-a-3d-atherosclerotic-carotid-artery-model
#11
Stein Fekkes, Abigail E S Swillens, Hendrik H G Hansen, Anne E C M Saris, Maartje M Nillesen, Francesco Iannaccone, Patrick Segers, Chris L de Korte
Three-dimensional strain estimation might improve the detection and localization of high strain regions in the carotid artery for identification of vulnerable plaques. This study compares 2D vs. 3D displacement estimation in terms of radial and circumferential strain using simulated ultrasound images of a patient specific 3D atherosclerotic carotid artery model at the bifurcation embedded in surrounding tissue generated with ABAQUS software. Global longitudinal motion was superimposed to the model based on literature data...
August 25, 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28102074/growth-of-a-large-area-free-standing-highly-conductive-and-fully-foldable-silver-film-with-inverted-pyramids-for-wearable-electronics-applications
#12
Xiao Yu, Zihua Li, Yong Liu, Wenxia Zhao, Ruimei Xu, Donghai Wang, Hui Shen
A promising new concept is the application of flexible and foldable conductive film or paper for wearable electronics, in which silver nanowires, carbon nanotubes, and graphene are primarily used as conductive materials. However, their insufficient nanostructure contacts lead to poor electrical conductivity and mechanical fracture. Here, we demonstrate a simple and innovative strategy for fabricating a free-standing silver film with inverted pyramids by replicating pyramids on a textured silicon wafer under a hydrothermal reaction...
February 2, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28077846/relaxation-in-technique-leading-to-new-beginnings
#13
Endre Koritar
This paper explores how standard analytic technique may result in a repetition of past traumatic experiences in the transference and countertransference analytic situation. Relaxation and elasticity of technique can lead to re-integration of previously fragmented ego functions, and in remembering and re-experiencing of previously repressed symbolic representations of fragmenting past traumatic experiences, resulting in neocatharsis and working through, thus healing wounds and scars sustained in self development...
December 2016: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/28056763/unsupervised-statistical-discovery-of-spaced-motifs-in-prokaryotic-genomes
#14
Hao Tong, Paul Schliekelman, Jan Mrázek
BACKGROUND: DNA sequences contain repetitive motifs which have various functions in the physiology of the organism. A number of methods have been developed for discovery of such sequence motifs with a primary focus on detection of regulatory motifs and particularly transcription factor binding sites. Most motif-finding methods apply probabilistic models to detect motifs characterized by unusually high number of copies of the motif in the analyzed sequences. RESULTS: We present a novel method for detection of pairs of motifs separated by spacers of variable nucleotide sequence but conserved length...
January 5, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28041797/sharp-wave-ripples-in-primates-are-enhanced-near-remembered-visual-objects
#15
Timothy K Leonard, Kari L Hoffman
The hippocampus plays an important role in memory for events that are distinct in space and time. One of the strongest, most synchronous neural signals produced by the hippocampus is the sharp-wave ripple (SWR), observed in a variety of mammalian species during offline behaviors, such as slow-wave sleep [1-3] and quiescent waking and pauses in exploration [4-8], leading to long-standing and widespread theories of its contribution to plasticity and memory during these inactive or immobile states [9-14]. Indeed, during sleep and waking inactivity, hippocampal SWRs in rodents appear to support spatial long-term and working memory [4, 15-23], but so far, they have not been linked to memory in primates...
January 23, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28040935/high-repetition-pump-and-probe-photoemission-spectroscopy-based-on-a-compact-fiber-laser-system
#16
Y Ishida, T Otsu, A Ozawa, K Yaji, S Tani, S Shin, Y Kobayashi
The paper describes a time-resolved photoemission (TRPES) apparatus equipped with a Yb-doped fiber laser system delivering 1.2-eV pump and 5.9-eV probe pulses at the repetition rate of 95 MHz. Time and energy resolutions are 11.3 meV and ∼310 fs, respectively, the latter is estimated by performing TRPES on a highly oriented pyrolytic graphite (HOPG). The high repetition rate is suited for achieving high signal-to-noise ratio in TRPES spectra, thereby facilitating investigations of ultrafast electronic dynamics in the low pump fluence (p) region...
December 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28033112/three-dimensional-ultrasound-strain-imaging-of-skeletal-muscles
#17
K Gijsbertse, A M J Sprengers, M M Nillesen, H H G Hansen, R G P Lopata, N Verdonschot, C L de Korte
In this study, a multi-dimensional strain estimation method is presented to assess local relative deformation in three orthogonal directions in 3D space of skeletal muscles during voluntary contractions. A rigid translation and compressive deformation of a block phantom, that mimics muscle contraction, is used as experimental validation of the 3D technique and to compare its performance with respect to a 2D based technique. Axial, lateral and (in case of 3D) elevational displacements are estimated using a cross-correlation based displacement estimation algorithm...
January 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27987375/stimulus-specific-adaptation-to-visual-but-not-auditory-motion-direction-in-the-barn-owl-s-optic-tectum
#18
Dante F Wasmuht, Jose L Pena, Yoram Gutfreund
Whether the auditory and visual systems use a similar coding strategy to represent motion direction is an open question. We investigated this question in the barn owl's optic tectum (OT) testing stimulus-specific adaptation (SSA) to the direction of motion. SSA, the reduction of the response to a repetitive stimulus that does not generalize to other stimuli, has been well established in OT neurons. SSA suggests a separate representation of the adapted stimulus in upstream pathways. So far, only SSA to static stimuli has been studied in the OT...
February 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27959815/ventral-tegmental-area-dopamine-neurons-firing-model-reveals-prenatal-nicotine-induced-alterations
#19
Andrei Dragomir, Yasemin M Akay, Die Zhang, Metin Akay
The dopamine (DA) neurons found in the Ventral Tegmental Area (VTA) are widely involved in the addiction and natural reward circuitry of the brain. Their firing patterns were shown to be important modulators of dopamine release and repetitive burst-like firing activity was highlighted as a major firing pattern of DA neurons in the VTA. In the present study we use a state space model to characterize the DA neurons firing patterns, and trace transitions of neural activity through bursting and non-bursting states...
December 6, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/27923717/characterization-of-exploratory-activity-and-learning-ability-of-healthy-and-schizophrenia-like-rats-in-a-square-corridor-system-ambitus
#20
G Horvath, P Liszli, G Kekesi, A Büki, G Benedek
The rodent tasks with food rewards are useful methods to evaluate memory functions, including hole-board and corridor tests. The AMBITUS system (a square corridor with several food rewards), as a combination of these tests, was developed for the investigation of a variety of parameters associated with exploration and cognitive performance in rodents. Experiments were performed to characterize these behaviors in healthy rats and a new "schizophrenia-like" rat substrain with impaired learning ability to reveal the reliability in tests related to these functions...
February 1, 2017: Physiology & Behavior
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