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Splenic rupture

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https://www.readbyqxmd.com/read/28936875/hemosuccus-pancreaticus-secondary-to-pseudoaneurysm-of-the-splenic-artery
#1
Mariano José Parada Blázquez, Andrea Núñez Ortiz
A 41-years-old male who presents abdominal pain and rectal bleeding with acute anemization. Both the gastroscopy and the colonoscopy dont identify any potential cause of bleeding. The computed tomography (CT) shows a pseudoaneurysm of the splenic artery. Gastrointestinal bleeding was attributed to a hemosuccus pancreaticus secondary to the pseudoaneurysm of the splenic artery. An arteriography was performed to embolize it. Pseudoaneurysm of the splenic artery is a rare cause of gastrointestinal bleeding. Given the risk of a rupture, the treatment is mandatory irrespective of the size or symptoms...
September 22, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28876573/hemosuccus-pancreaticus-from-ruptured-splenic-vein-pseudoaneurysm-secondary-to-necrotizing-pancreatitis-a-case-report
#2
M L Medina, C Saroca
Hemosuccus pancreaticus is a rare cause of gastrointestinal bleeding in which haemorrhage occurs from the ampulla of vater via the pancreatic duct, mostly from ruptured pseudoaneurysms. Our patient is a 25-year-old Filipino male who presented with intermittent epigastric pain associated with melena and decreasing haemoglobin despite multiple blood transfusions. EGD showed erythematous gastric and duodenal mucosa with no evidence of active bleeding. Whole abdominal CT scan with IV contrast showed diffusely prominent pancreas with areas of non-enhancement suggestive necrosis...
September 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28859168/p2x7-receptor-drives-th1-cell-differentiation-and-controls-the-follicular-helper-t-cell-population-to-protect-against-plasmodium-chabaudi-malaria
#3
Érika Machado de Salles, Maria Nogueira de Menezes, Renan Siqueira, Henrique Borges da Silva, Eduardo Pinheiro Amaral, Sheyla Inés Castillo-Méndez, Isabela Cunha, Alexandra Dos Anjos Cassado, Flávia Sarmento Vieira, David Nicholas Olivieri, Carlos Eduardo Tadokoro, José Maria Alvarez, Robson Coutinho-Silva, Maria Regina D'Império-Lima
A complete understanding of the mechanisms underlying the acquisition of protective immunity is crucial to improve vaccine strategies to eradicate malaria. However, it is still unclear whether recognition of damage signals influences the immune response to Plasmodium infection. Adenosine triphosphate (ATP) accumulates in infected erythrocytes and is released into the extracellular milieu through ion channels in the erythrocyte membrane or upon erythrocyte rupture. The P2X7 receptor senses extracellular ATP and induces CD4 T cell activation and death...
August 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28846949/splenic-hamartoma-associated-with-thrombocytopenia-a-case-report
#4
Toshiaki Komo, Jun Hihara, Mikihiro Kanou, Toshihiko Kohashi, Ichiro Ohmori, Masanori Yoshimitsu, Takuhiro Ikeda, Akira Nakashima, Masashi Miguchi, Ichiko Yamakita, Hidenori Mukaida, Naoki Hirabayashi, Mayumi Kaneko
INTRODUCTION: Hamartomas are rare, benign tumors of the spleen. Few cases of splenic hamartomas associated with thrombocytopenia have been reported. PRESENTATION OF CASE: An asymptomatic 64-year-old man with myelodysplastic syndrome was found to have a splenic tumor. Laboratory tests were significant for thrombocytopenia, with a platelet count of 7.8×10(4)/μL. Ultrasonography showed splenomegaly (10.8×6.6cm), and a hypoechoic splenic mass (8.0×7.0cm). Color doppler ultrasound revealed blood flow within the mass, and the mass density was homogeneous on abdominal computed tomography (CT)...
August 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28833474/short-term-side-effects-and-attitudes-towards-second-donation-a-comparison-of-related-and-unrelated-haematopoietic-stem-cell-donors
#5
Simon Pahnke, Gunnar Larfors, Ulla Axdorph-Nygell, Anne Fischer-Nielsen, Eva Haastrup, Dag Heldal, Maija Itälä-Remes, Jan-Erik Johansson, Marjut Kauppila, Stig Lenhoff, Per Ljungman, Riita Niittyvuopio, Anna Sandstedt, Hans Hägglund
The Nordic Register of Haematopoietic Stem Cell Donors (NRHSD) has registered related and unrelated donors from 10 transplant centres in Sweden, Norway, Finland and Denmark since 1998. We present a prospective, observational study of 1,957 donors, focusing mainly on the differences between related and unrelated donors. Related donors are reported to have more comorbidities, but similar side effects compared with unrelated donors. Side effects after BM or PBSC donation are generally of short duration and in this study no deaths, myocardial infarctions, splenic ruptures, or thromboembolic events are reported...
August 18, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/28832081/primary-splenic-pregnancy-a-rare-but-imperative-cause-of-hemoperitoneum-case-report-and-review-of-literature
#6
Ruchi Rathore, Shilpi Shilpi, Ratna Chopra, Namrata Nargotra
Primary splenic pregnancy is an extremely rare form of extratubal ectopic pregnancy. These cases often cause splenic rupture in very early course of their gestation thereby presenting with hemoperitoneum in emergencies. Owing to the higher risk of exsanguination and death caused by hemoperitoneum, it is essential to diagnose these cases for proper management and better prognosis of the patients. We present the case of a 23-year-old female, gravida 2, para 1, live issue 1 presenting to the emergency outpatient department with acute abdomen and hemoperitoneum...
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28819576/pitfall-in-the-diagnosis-of-diabetes-insipidus-and-pregnancy
#7
Melissa Sum, Jessica B Fleischer, Alexander G Khandji, Sharon L Wardlaw
Diabetes insipidus (DI) during pregnancy and the perinatal period is an uncommon medical problem characterized by polyuria and excessive thirst. Diagnosis of DI may be overlooked in the setting of pregnancy, a time when increased water intake and urine output are commonly reported. We report two cases: one of transient DI in a young woman during her third trimester of twin pregnancy in association with acute fatty liver and hypertension and one of postpartum DI secondary to Sheehan syndrome from rupture of a splenic artery aneurysm...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28819484/-spontaneous-splenic-rupture-about-a-case-and-review-of-the-literature
#8
REVIEW
Safae El Abbadi, Fatima Zahra Rhouni, Laila Jroundi
This study reports a case of spontaneous subcapsular splenic ruptured hematoma (with hemoperitoneum) and provides update on this rare disease. Non-traumatic ruptures can be fatal. Diagnosis is sometimes difficult. They often reveal an underlying pathology including infections, tumors or hematologic disorders. Symptomatology commonly has an abrupt onset but progressive forms are also possible. The majority of patients undergo splenectomy.
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28808809/evidence-of-dengue-virus-replication-in-a-non-traumatic-spleen-rupture-case
#9
Luiz José de Souza, João de Azevedo, Liza Ingride Acha Kohler, Lorena de Freitas Barros, Mariana Arêdes Lima, Emiliana Mandarano Silva, Ronaldo Mohana-Borges, Priscila Conrado Guerra Nunes, Marciano Viana Paes
The present report describes a case of splenic rupture due to dengue, a rare complication of dengue that should be considered in any patient with suspected dengue disease who started with left upper quadrant abdominal pain and hypotension. The pathophysiology of this entity is not yet well elucidated, but one of the theories present in the literature is that it is due to a depletion of coagulation factors and platelets leading to intra-splenic hemorrhage and rupture. The RT-PCR technique detected serotype 1 and histopathological studies of the spleen revealed significant atrophy of lymphoid follicles and extensive hemorrhage areas...
August 14, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28790101/splenic-rupture-following-synchronised-direct-current-cardioversion
#10
Nicholas Kaufman, David Ferraro
Atraumatic rupture of the normal spleen is a rare entity. Often, a triggering factor or minor physical event can be ascribed as the aetiology for rupture, including coughing, vomiting or minor medical procedures not involving the spleen. A 65-year-old man who was hospitalised for eosinophilic pneumonia developed haemodynamically unstable atrial flutter that necessitated urgent synchronised direct current cardioversion (DCCV). Two hours after successful cardioversion, he developed signs of an acute abdomen with free intraperitoneal fluid identified on bedside ultrasonography...
August 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28770130/an-extremely-premature-neonate-with-severe-anemia
#11
Swosti Joshi, Ivy Mulinge, Medha Kamat
Spleen rupture in an extremely premature newborn is very rare event. High index of suspicion is required to make timely diagnosis and thereafter appropriate management. We present a rare case of an extremely premature, extremely low birthweight newborn who presented with severe anemia secondary to splenic rupture. It was managed conservatively without splenectomy resulting in complete resolution of symptoms. Although non-operative management of pediatric splenic injuries is now recognized as the treatment of choice, there is very little experience in premature newborns...
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28762583/case-of-spontaneous-splenic-rupture-caused-by-ectopic-pregnancy-in-the-spleen
#12
Bao-Qiang Wu, Feng Zhu, Yong Jiang, Dong-Lin Sun
Splenic ectopic pregnancy refers to the implantation of the oosperm in the spleen. If not diagnosed early, the results of this phenomenon would almost certainly be splenic rupture, which is equivalent to the spontaneous rupture of the spleen. If the patient has no history of trauma, it is difficult to diagnose this condition early and an explicit diagnosis is often obtained by exploratory laparotomy. We report the case of a 27-year-old woman who was admitted to the hospital due to abdominal pain and hemorrhagic shock...
August 1, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28737217/splenic-rupture-following-temporary-cessation-of-ibrutinib
#13
David Dutton, Huw Roach, Lisa Lowry
No abstract text is available yet for this article.
July 24, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28723778/thoracic-splenosis-mimicking-a-pleuropneumonia-a-case-report
#14
Aurélie Baldolli, Solène Coeuret, Vincent Le Pennec, Denis Agostini, Renaud Verdon
RATIONALE: Splenosis is the development of one or more heterotopic splenic tissue autoimplants following rupture of the spleen and remains mostly asymptomatic. PATIENT CONCERNS: We report a case of a 50-year old post-traumatic splenectomized man admitted for a left side community acquired pneumonia resistant to antibiotics. DIAGNOSES: The diagnosis of intrathoracic ectopic spleen was suspected because of the history of spleen trauma with diaphragm rupture and the absence of Howell-Jolly bodies...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28717782/splenic-artery-aneurysm-with-the-double-rupture-phenomenon
#15
Jung Ho Kim, Han Sol Chung, Jong Ha Kim, Sin Youl Park, Sam Beom Lee, Byung Soo Do
Splenic artery aneurysm is the third most common type of intra-abdominal aneurysm, with a prevalence rate of 0.01% to 10.4% in the general population. Splenic artery aneurysm is usually asymptomatic and is typically detected by chance and does not require surgical management; however, if rupture occurs, although rare, the patient's situation can become critical. We report our experience with a man who presented with left flank and left shoulder pain. His symptoms were caused by multiple hematomas confined to the spleen, but 2 days after admission, he developed delayed hemoperitoneum and required surgical management...
June 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/28704210/factor-xiii-deficiency-in-south-of-tunisia
#16
Ines Maaloul, Moez Medhaffer, Nacim Louhichi, Imen Krichen, Sofien Alibi, Sana Kmiha, Hajer Aloulou, Faiza Fakhfakh, Moez Elloumi, Choumous Kallel, Mongia Hachicha
: Factor XIII deficiency is a rare autosomal recessive disorder of hemostasis characterized by a plasmatic factor XIII level less than 1% in homozygote and bleeding as of the youth. The aim of the study is to describe the clinical features and the outcome of the patients and to determine molecular characteristics. A retrospective study, was conducted on seven patients with factor XIII deficiency in the department of hematology and pediatrics, Hedi Chaker Hospital, Sfax, Tunisia during the period of 14 years (2001-2014)...
September 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28702168/familial-spontaneous-splenic-rupture-in-a-patient-with-idiopathic-splenomegaly-report-of-a-case
#17
Ilsalien S Bakker, Rutger J Hissink, Hendrik M Schaap
Spontaneous splenic rupture in a healthy individual is a rare phenomenon. This article reports on a patient with an uneventful medical history, presenting with atraumatic splenic rupture. Three family members of the patients experienced the same in the past.
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28670065/aortic-valve-perforation-secondary-to-blunt-force-trauma
#18
Sachin Mehta, Gibbs Wilson, Keith Suarez, Christopher D Chiles
Blunt chest trauma has seldom been reported as a cause of rupture of an aortic valve cusp. We report the case of a 63-year-old man who had a motor vehicle collision resulting in transection of the descending thoracic aorta, splenic pseudoaneurysm, and rupture of an aortic valve cusp causing severe aortic regurgitation. Despite replacement of the aortic valve, he died of multiorgan failure.
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28664233/endovascular-treatment-of-wide-necked-visceral-artery-aneurysms-using-the-neurovascular-comaneci-neck-bridging-device-a-technical-report
#19
Julian Maingard, Hong Kuan Kok, Emma Phelan, Caitriona Logan, Dinesh Ranatunga, Duncan Mark Brooks, Ronil V Chandra, Michael J Lee, Hamed Asadi
INTRODUCTION: Visceral and renal artery aneurysms (VRAAs) are an uncommon clinical entity but carry a risk of rupture with associated morbidity and mortality. The rupture risk is particularly high when the aneurysms are large, of unfavourable morphology or in the setting of pregnancy and perioperative period. Endovascular approaches are now first line in the treatment of VRAA, but conventional techniques may be ineffective in excluding aneurysms with unfavourable anatomy such as those with wide necks or at arterial bifurcation points...
June 29, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28640113/spleen-implanting-in-the-fatty-liver-mimicking-hepatocarcinoma-in-a-patient-with-hepatitis-b-c-a-case-report-and-literature-review
#20
REVIEW
Meng-Yao Wang, Bao Li, Dan Chen, Ai-Lian Liu, Sahrish Qamar, Mei-Yu Sun
RATIONALE: Ectopic splenic autotransplantation refers to the heterotopic autotransplantation of splenic tissue and no treatment is necessary for it when patient is asymptomatic. Its incidence rate is reported up to 67% among patients with a history of splenic trauma and splenic surgery. The diagnosis of it before operation is really difficult, and it is easy to mimic as other tumors. PATIENT CONCERNS: We reported a 42-year-old man with hepatic splenosis, with history of splenectomy for traumatic splenic rupture 16 years ago and hepatitis B&C...
June 2017: Medicine (Baltimore)
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