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Functional endoscopic sinus

Hannah N Kuhar, Bobby A Tajudeen, Mahboobeh Mahdavinia, Ashley Heilingoetter, Ashwin Ganti, Paolo Gattuso, Ritu Ghai, Pete S Batra
BACKGROUND: Chronic rhinosinusitis (CRS) is an inflammatory disease process with several different phenotypes. Recent data has shown that CRS phenotypes maintain distinct nasal microbiota that may predict surgical outcomes. Nasal microbiota and structured histopathologic reporting have the potential to further differentiate subtypes and provide additional insight into the pathophysiology of CRS. METHODS: Sinus swabs collected during functional endoscopic sinus surgery (FESS) were studied by polymerase chain reaction analysis of 16S ribosomal RNA...
September 21, 2018: International Forum of Allergy & Rhinology
Linqi Wei, Yonghong Zhang, Huazhang Tan
This study aimed to investigate the changes of tumor necrosis factor-α (TNF-α), platelet-derived factor (PDGF), hyaluronic acid (HA) in nasal secretions and olfactory function in patients with chronic sinusitis before and after endoscopic sinus surgery. A total of 94 patients with chronic sinusitis treated at Xiangyang No.1 People's Hospital, Hubei University of Medicine (Xiangyang, China) from May 2016 to April 2017 were randomly divided into the control and observation groups, with 47 patients in each group...
October 2018: Experimental and Therapeutic Medicine
Mario Dauri, Roberta Di Mauro, Fabiana Lucci, Federica Martino, Maria B Silvi, Eleonora Gidaro, Santo Di Lorenzo, Nicola Toschi, Stefano Di Girolamo
No abstract text is available yet for this article.
September 18, 2018: Minerva Anestesiologica
Mahmoud Nejabat, Golnoush Sadat Mahmoudi Nezhad, Saeedeh Shenavandeh, Mohammad Javad Ashraf, Mohammad Hassan Jalalpour
Purpose: To report a case of prolonged conjunctivitis as the manifestation of Granulomatosis with polyangiitis (GPA). Methods: A 37-year-old man presented with prolonged conjunctivitis which had persisted for one month. He was taking medication for his conjunctivitis without any response. A slit-lamp examination revealed conjunctivitis and scleritis in the right eye. Conjunctivitis, 360-degree peripheral corneal thinning, corneal perforation, and scleritis were seen in the left eye...
September 2018: Journal of Current Ophthalmology
Haribalan Kumar, Ravi Jain
Nasal surgery improves symptoms in a majority of patients for whom medical treatment has failed. In rhinosinusitis patients, endoscopic sinus surgery aims to alleviate obstruction and re-establish mucociliary clearance. Surgery alters the structure-function relationship within the nasal passage, which is difficult to assess clinically. Computational modelling has been used to investigate this relationship by simulating air flow and environmental variables inside realistic three-dimensional models of the human nasal airway but many questions remain unanswered and need further investigation...
February 8, 2018: Clinical Biomechanics
Salomon Cohen-Cohen, Paul A Gardner, Joao T Alves-Belo, Huy Q Truong, Carl H Snyderman, Eric W Wang, Juan C Fernandez-Miranda
OBJECTIVE Pituitary adenomas often invade the medial wall of the cavernous sinus (CS), but this structure is generally not surgically removed because of the risk of vascular and cranial nerve injury. The purpose of this study was to report the surgical outcomes in a large series of cases of invasive pituitary adenoma in which the medial wall of the CS was selectively removed following an anatomically based, stepwise surgical technique. METHODS The authors' institutional database was reviewed to identify cases of pituitary adenoma with isolated invasion of the medial wall, based on an intraoperative evaluation, in which patients underwent an endoscopic endonasal approach with selective resection of the medial wall of the CS...
September 7, 2018: Journal of Neurosurgery
Jin-Ho Joo, Ji Sang Han, Shin-Myeong Choi, In-Ki Park, Jae-Ho Shin
INTRODUCTION: Rhabdomyosarcoma is uncommon in adults. Adult and maxillary rhabomyosarcoma with direct orbital extension has been rarely reported. To our knowledge, there is no reported case about adult patient with alveolar maxillary rhabdomyosarcoma and orbital extension survived 1 year with intact ocular function. CASE PRESENTATION: A 21-year-old female presented with protrusion of the right eye and an obstructed nasal passage for the past month. Her symptoms were not relieved by oral antibiotic or irrigation...
August 2018: Medicine (Baltimore)
Ran Duan, Jun Shi, Mathias Tremp, Carlo M Oranges, Bowen Gao, Feng Xie, Qingfeng Li
A patient presented with a complex penetrating facial wound by high temperature steel. The hot steel penetrated right temple, ethmoid bone, and maxillary sinus, and then exited from his left cheek. He kept his right eye but lost his sight. For functional and esthetic considerations, treatments were provided in a staged procedure. First, the debridement was performed under the endoscope. The dead bone was removed, broken teeth were extracted, and necrotic tissue was cleaned. The exposed wounds were cleaned, and dressing was changed daily until the exudation was widely reduced...
August 28, 2018: Journal of Craniofacial Surgery
Peter Papagiannopoulos, Hannah N Kuhar, Anish Raman, Ashwin Ganti, Paolo Gattuso, Pete S Batra, Bobby A Tajudeen
Background Chronic rhinosinusitis (CRS) is a frequently observed condition in patients with immunodeficiency secondary to immunosuppressive medications. The histologic features of CRS among patients undergoing immunosuppressive treatment have yet to be determined and may have important implications on understanding the pathophysiology of the disease process. Methods A structured histopathology report was utilized to analyze sinus tissue removed during functional endoscopic sinus surgery (FESS). Histopathology variables, Lund-Mackay score (LMS), and sinonasal outcome test 22 scores were compared among patients with CRS on immunosuppressive therapy (CRSi), CRS without nasal polyps (CRSsNP) patients, and CRS with nasal polyps (CRSwNP) patients...
August 28, 2018: American Journal of Rhinology & Allergy
Madison Buras, Alberto Simoncini, Anil Gungor
BACKGROUND: Cystic Fibrosis is an autosomal recessive disorder with a mutation in the cystic fibrosis transmembrane regulator gene, leading to dysregulation of epithelial fluid transport, dehydration of airway surfaces and impaired mucociliary function in the sinuses, lungs, pancreas and other organs. This leads to thickened secretion which blocks the sinus ostia and promotes chronic bacterial overgrowth and destruction of the mucosa. Chronic rhinosinusitis in cystic fibrosis patients leads to a decreased quality of life involving increased hospitalizations, infections, pneumonia, and acute exacerbations, warranting multiple sinus surgeries...
August 18, 2018: American Journal of Otolaryngology
Navdeep R Sayal, Eytan Keider, Shant Korkigian
Balloon sinus dilation (BSD) is generally accepted as a safe alternative to traditional sinus surgery. It is a unique technique designed to potentially minimize complications associated with traditional functional endoscopic sinus surgery (FESS). We present a case in which a 65-year-old man experienced a cerebrospinal fluid (CSF) leak in the ethmoid roof that was visualized instantly after balloon dilation in a revision sinus surgery. In this case report, we discuss the causes of CSF leaks and explain in detail the immediate endoscopic repair with a collagen matrix...
August 2018: Ear, Nose, & Throat Journal
Fatih Arslan, Serdar Tasdemir, Abdullah Durmaz, Fuat Tosun
Chronic rhinosinusitis with nasal polyposis is a chronic inflammatory disease of the respiratory mucosa of the nasal cavity and paranasal sinuses. The aim of this study was investigate the effect of nasal obstruction related to chronic rhinosinusitis with nasal polyposis on cognitive functions. Patients with chronic rhinosinusitis with nasal polyposis causing bilateral total or near total nasal obstruction were enrolled in the study. Symptoms of nasal congestion, loss of smell, postnasal drip, headaches, snoring, concentration difficulties and blunted affect were evaluated by Visual Analog Scale...
August 2018: Cognitive Neurodynamics
Mohsen Naraghi, Neda Baghbanian, Melorina Moharari, Amene Saghazadeh
OBJECTIVES: Mucociliary clearance is an important defense mechanism for upper and lower airway. Chronic rhinosinusitis has been frequently associated with mucociliary dysfunction. Endoscopic sinus surgery (ESS) is recommended for treatment-resistant sinusitis in order to improve mucociliary function. The present study investigated the effect of ESS on the saccharin time (mucociliary clearance time) in relation to symptom profile assessed by the Sino-nasal Outcome Test (SNOT)-22, and disease severity based on the Lund-Kennedy endoscopic scores and Lund-Mackay computed tomographic (CT) scores...
July 25, 2018: American Journal of Otolaryngology
Kelsey A Roelofs, Victoria Starks, Michael K Yoon
PURPOSE: The objective of this study was to report a case of persistent and likely self-induced orbital emphysema (OE) following functional endoscopic sinus surgery with dislodgement of a previously placed orbital floor implant and to review the literature surrounding etiologies, pathophysiology, and management of OE. METHODS: Case report and review of the literature. RESULTS AND DISCUSSION: While blunt trauma resulting in disruption of the medial orbital wall is the most common cause of OE, there are an additional 25 underlying etiologies reported in the current literature...
August 20, 2018: Ophthalmic Plastic and Reconstructive Surgery
Vannessa Leung, Hamish Dunn, Allison Newey, Brett O'Donnell
Sinusitis complicated by orbital apex syndrome is rare. The majority of cases are due to mucormycosis in immunocompromised patients. The authors report a case of orbital apex syndrome secondary to Pseudomonas sinusitis. The patient was a 79-year-old Type 2 diabetic woman who underwent left-sided functional endoscopic sinus surgery. Three months postprocedure, she presented with a 3-week history of gradual vision loss and constant temporal headache on the ipsilateral side. Examination revealed light perception vision, a relative afferent pupillary defect, absent corneal reflex, and disc pallor...
September 2018: Ophthalmic Plastic and Reconstructive Surgery
Andrew J Thomas, Kristine A Smith, Christopher I Newberry, Brandon Cardon, Brock Davis, Zhining Ou, Angela P Presson, Jeremy D Meier, Jeremiah A Alt
BACKGROUND: Understanding the variation in costs of endoscopic sinus surgery (ESS) is critical to defining value. Current published costs of ESS have not identified potential sources of variation. Our objective was to analyze ESS costs to identify sources of variance that could guide value-improving decisions. METHODS: ESS cases (n = 1739) performed between 2008 and 2016 were identified from a database of 22 rural to tertiary facilities. Cost and time data were extracted from the database...
August 17, 2018: International Forum of Allergy & Rhinology
Jesada Kanjanaumporn, Peter H Hwang
Background The concept of unified airway disease has linked bronchiectasis with chronic rhinosinusitis (CRS), much in the same way as in asthma and CRS. Although the outcomes of endoscopic sinus surgery (ESS) on comorbid asthma have been relatively well studied, the outcomes of ESS on comorbid bronchiectasis have rarely been examined. Objective We sought to determine sinonasal and pulmonary clinical outcomes of ESS in bronchiectasis patients with CRS. Method We reviewed all bronchiectasis patients who had ESS for CRS at our institution from 2006 to present...
September 2018: American Journal of Rhinology & Allergy
Venkatesh Anehosur, Abhijit Joshi, Saravanan Rajendiran
Management of condylar fractures is a highly controversial and debatable area. Open reduction and internal fixation (ORIF) using an extraoral approach has certain benefits over the nonsurgical treatment. Risk of damage to the facial nerve and an extraoral scar remains constant deterrents. An endoscopic-assisted ORIF offers an intraoral approach, thus eliminating consequences such as scarring. Though this technique offers unparalleled advantages, it is associated with a steep learning curve. Surgical results improve only with patience and experience...
September 2018: Craniomaxillofacial Trauma & Reconstruction
Krunal Patel, Angelos G Kolias, Thomas Santarius, Richard J Mannion, Ramez W Kirollos
BACKGROUND: Endoscopic endonasal surgery (EES) is increasingly used for olfactory groove meningiomas (OGMs). The role of EES for large (≥4 cm) or complex OGMs is debated. Specific imaging features have been reported to affect the degree of gross total resection (GTR) and complications following EES for OGMs. The influence of these factors on transcranial resection (TCR) is unknown. OBJECTIVE: To examine the impact of specific imaging features on outcome following TCR to provide a standard for large and endoscopically less favorable OGMs against which endoscopic outcomes can be compared...
July 31, 2018: Operative Neurosurgery (Hagerstown, Md.)
David W Jang, Cecily Abraham, Derek D Cyr, Kristine Schulz, Ralph Abi Hachem, David L Witsell
Objective This study uses a large national claims-based database to analyze recent practice patterns related to balloon catheter dilation (BCD) of the sinuses. Study Design Retrospective study. Setting Academic. Subjects and Methods Patients with chronic rhinosinusitis (CRS) undergoing BCD and functional endoscopic sinus surgery (FESS) from 2011 to 2014 were identified in Truven Health MarketScan Databases with codes from the International Classification of Diseases, Ninth Revision, Clinical Modification and Current Procedural Terminology, Fourth Edition...
August 7, 2018: Otolaryngology—Head and Neck Surgery
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