keyword
https://read.qxmd.com/read/38535582/brucellar-endocarditis-of-the-tricuspid-valve-a-case-report-and-review-of-the-literature
#1
Evangelo Boumis, Pierangelo Chinello, Vincenzo Galati, Simone Topino, Francesca Gavaruzzi, Stefania Cicalini
Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure. Right-sided endocarditis, a very uncommon presentation of brucellosis, may be associated with a better prognosis. We describe the case of a 72-year-old woman admitted to our institution with a persistent fever and multiple pulmonary infiltrates. Transthoracic echocardiography and serologic tests led to the diagnosis of brucellar tricuspid endocarditis...
March 8, 2024: Pathogens
https://read.qxmd.com/read/38534712/multiple-drug-resistant-streptococcus-strains-an-actual-problem-in-pig-farms-in-western-romania
#2
JOURNAL ARTICLE
Luminita Costinar, Corina Badea, Adela Marcu, Corina Pascu, Viorel Herman
Streptococci are a type of bacteria that can cause severe illnesses in humans and animals. Some typical species like S. suis , or atypical species like S. porcinus and, S. dysgalactiae subsp. dysgalactiae , can cause infections like septicemia, meningitis, endocarditis, arthritis, and septic shock. S. suis is considered a newly emerging zoonotic pathogen. Although human streptococcal infection outbreaks are rare, it is appropriate to review the main streptococcal species isolated in pig farms in western Romania, due to the high degree of antibiotic resistance among most isolates commonly used in human treatment...
March 19, 2024: Antibiotics
https://read.qxmd.com/read/38533941/conservative-versus-surgical-therapy-in-patients-with-infective-endocarditis-and-surgical-indication-meta-analysis-of-reconstructed-time-to-event-data
#3
JOURNAL ARTICLE
Tulio Caldonazo, Stefan Hagel, Torsten Doenst, Hristo Kirov, Michel Pompeu Sá, Xander Jacquemyn, Panagiotis Tasoudis, Marcus Franz, Mahmoud Diab
BACKGROUND: Infective endocarditis represents a life-threatening disease with high mortality rates. A fraction of patients receives exclusively conservative antibiotic treatment due to their comorbidities and high operative risk, despite fulfilling criteria for surgical therapy. The aim of the present study is to compare outcomes in patients with infective endocarditis and indication for surgical therapy in those who underwent or did not undergo valve surgery. METHODS AND RESULTS: Three databases were systematically assessed...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38530156/standardized-order-set-for-the-management-of-infective-endocarditis
#4
JOURNAL ARTICLE
Kerneisha Murphy, Emily Eiswirth
BACKGROUND: Infective endocarditis (IE) is a potentially life-threatening infection that affects the inner lining of the heart, particularly the heart valves. Patients with preexisting heart conditions, damaged heart valves, or a history of intravenous drug use are at a higher risk of acquiring IE. LOCAL PROBLEM: A rural acute care facility reported that 68.75% of patients who had a methicillin-resistant Staphylococcus aureus infection were diagnosed with IE. Review of medical records showed that 65% of patients with IE did not have antibiotic start/stop dates and 51% were discharged before the 6-week completion date...
March 26, 2024: Journal of the American Association of Nurse Practitioners
https://read.qxmd.com/read/38529922/-staphylococcus-aureus-bacteraemia-cardiac-implantable-electronic-device-extraction-and-the-risk-of-recurrent-infection-a-retrospective-population-based-cohort-study
#5
JOURNAL ARTICLE
Andreas Berge, Casper Carlsén, Alexandros Petropoulos, Fredrik Gadler, Magnus Rasmussen
BACKGROUND: Patients with cardiac implantable electronic device (CIED) and Staphylococcus aureus bacteraemia (SAB) are at risk of having CIED infection, pocket infection or endocarditis. To avoid treatment failures, guidelines recommend that the CIED should be extracted in all cases of SAB butrecent studies indicate low extraction rates and low risk of relapse. The aim of the study was to describe a Swedish population-based cohort of patients with CIED and SAB, the rate of extraction, and treatment failure measured as recurrent SAB...
March 26, 2024: Infectious Diseases
https://read.qxmd.com/read/38529465/a-case-report-of-neuro-beh%C3%A3-et-syndrome-frequent-neurological-manifestations-concurrent-with-life-threatening-illnesses
#6
Omar Ballut, Mayas M Almahi, Banan S Alghamdi, Najla K Alzahrani, Maali A Alghamdi
​​​​Behçet disease (BD) is a recurrent, multisystemic autoimmune vasculitis that affects both small and large vessels. A combination of neurological signs and symptoms in BD is called neuro-Behçet syndrome (NBS). We present the case of a 31-year-old male diagnosed with chronic progressive NBS who presented with multiple relapsing episodes concurrent with infective endocarditis due to intravenous drug abuse, drug-induced hepatitis, acute kidney injury, and septic shock that is not related to BD...
February 2024: Curēus
https://read.qxmd.com/read/38525767/an-aminoglycoside-sparing-regimen-with-double-beta-lactam-to-successfully-treat-granulicatella-adiacens-prosthetic-aortic-valve-endocarditis-time-to-change-paradigm
#7
Alberto Pagotto, Floriana Campanile, Paola Conti, Francesca Prataviera, Paola Della Siega, Sarah Flammini, Simone Giuliano, Luca Martini, Davide Pecori, Assunta Sartor, Maria Screm, Tosca Semenzin, Carlo Tascini
(1) Background: Granulicatella adiacens is a former nutritionally variant streptococci (NVS). NVS infective endocarditis (IE) is generally characterized by a higher rate of morbidity and mortality, partially due to difficulties in choosing the most adequate microbiological culture method and the most effective treatment strategy, and partially due to higher rates of complications, such as heart failure, peripheral septic embolism, and peri-valvular abscess, as well as a higher rate of valve replacement. Depending on the affected valve (native valve endocarditisNVE, or prosthetic valve endocarditisPVE), the American Heart Association (AHA) 2015 treatment guidelines (GLs) suggest penicillin G, ampicillin, or ceftriaxone plus gentamicin (2 weeks for NVE and up to 6 weeks for PVE), while vancomycin alone may be a reasonable alternative in patients who are intolerant of β-lactam therapy...
March 14, 2024: Infectious Disease Reports
https://read.qxmd.com/read/38522137/magnolol-attenuates-macrophage-pyroptosis-triggered-by-streptococcus-equi-subsp-zooepidemicus
#8
JOURNAL ARTICLE
Yuxuan Liu, Meijun Lu, Qian Sun, Zheng Guo, Yongjin Lin, Shun Li, Yunfei Huang, Yajuan Li, Qiang Fu
Streptococcus equi subsp. zooepidemicus (SEZ) is a zoonotic bacterial pathogen that causes life-threatening infections and various diseases such as meningitis, endocarditis and pneumonia. With the use of antibiotics being severely restricted in the international community, an alternative to antibiotics is urgently needed against bacterial. In the present study, the herbal extract magnolol protected mice against SEZ infection, reflected by increased survival rate and reduced bacterial burden. A pro-inflammatory form of cell death occurred in SEZ-infected macrophage...
March 23, 2024: International Immunopharmacology
https://read.qxmd.com/read/38521543/sex-differences-and-outcomes-in-surgical-infective-endocarditis
#9
JOURNAL ARTICLE
Juliette Leterrier, Bernard Iung, Christian de Tymoski, Laurene Deconinck, Marylou Para, Xavier Duval, Sophie Provenchere, Jules Mesnier, Clemence Delhomme, Skerdi Haviari, Marina Urena, Gaspard Suc
BACKGROUND: Cardiac surgery for infective endocarditis (IE) is associated with significant hospital mortality, and female sex may be associated with worse outcomes. However, the impact of sex on the presenting characteristics, management, and outcomes of patients operated for acute infective endocarditis (IE) has not been adequately studied. OBJECTIVE: The aim of our study was to analyze differences in management and outcome of IE between women and men who undergo surgery...
March 23, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38521440/valvulitis-a-new-echocardiographic-criterion-for-the-diagnosis-of-bioprosthetic-aortic-valve-infective-endocarditis
#10
JOURNAL ARTICLE
Pablo Zulet, Isidre Vilacosta, Eduardo Pozo, Daniel García Arribas, Carlos Nicolás Pérez-García, Manuel Carnero, Daniel Pérez Camargo, Lourdes Montero, Melchor Saiz Pardo, Patricia Mahía, Adrián Jerónimo, Fabián Islas, Daniel Gómez, José Alberto San Román, José Alberto De Agustín, Carmen Olmos
INTRODUCTION AND OBJECTIVES: Diffuse homogeneous hypoechoic leaflet thickening, with a wavy leaflet motion documented by transesophageal echocardiography (TEE), has been described in some cases of prosthetic valve endocarditis (PVE) involving aortic bioprosthesis (AoBio-PVE). This echocardiographic finding has been termed valvulitis. We aimed to estimate the prevalence of valvulitis, precisely describe its echocardiographic characteristics, and determine their clinical significance in patients with AoBio-PVE...
March 21, 2024: Revista Española de Cardiología
https://read.qxmd.com/read/38520419/penicillin-allergy-reassessment-for-treatment-improvement-a-dental-office-tool-to-support-appropriate-penicillin-allergy-labeling
#11
JOURNAL ARTICLE
Ashlan J Kunz Coyne, Dana Holger, Erinne Kennedy, Mackenzie Connell, Juliann Binienda, Christopher Giuliano, Elaine M Bailey
BACKGROUND: Dental appointments offer an opportunity to evaluate a documented penicillin (PCN) allergy and determine whether the patient might be a candidate for medical reassessment of their allergy. The authors gathered feedback on the Penicillin Allergy Reassessment for Treatment Improvement (PARTI) tool, designed to enhance dentist-patient communications regarding PCN allergies. METHODS: From January 2022 through May 2023, the authors conducted a mixed-methods study, collecting focus group data from patients with PCN allergies and surveying health care workers (HCWs) regarding the PARTI tool...
March 21, 2024: Journal of the American Dental Association
https://read.qxmd.com/read/38515536/-mycoplasma-bovis-mastitis-in-dairy-cattle
#12
REVIEW
Aga E Gelgie, Sarah E Desai, Benti D Gelalcha, Oudessa Kerro Dego
Mycoplasma bovis has recently been identified increasingly in dairy cows causing huge economic losses to the dairy industry. M. bovis is a causative agent for mastitis, pneumonia, endometritis, endocarditis, arthritis, otitis media, and many other clinical symptoms in cattle. However, some infected cows are asymptomatic or may not shed the pathogen for weeks to years. This characteristic of M. bovis , along with the lack of adequate testing and identification methods in many parts of the world until recently, has allowed the M...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38506314/publication-trends-on-infective-endocarditis-comprehensive-bibliometric-analysis-and-visualization-between-1892-and-2022
#13
JOURNAL ARTICLE
Yağmur Ekenoğlu Merdan, Okan Aydoğan
BACKGROUND: In recent years, studies reported that the incidence of infective endocarditis (IE) has increased despite the decrease in rheumatic heart diseases, great advances in medical and surgical treatment methods, and prophylactic antibiotic therapies. However, there is no bibliometric analysis based on the visual mapping method in the literature. In the study, we aimed to analyze the hot topics in IE, the distribution of publications in terms of country, institution, journal, author, and their relationships by assessing IE articles published in the 130 years between 1892 and 2022...
March 20, 2024: Anatolian Journal of Cardiology
https://read.qxmd.com/read/38504421/pericardial-effusion-in-association-with-periodontitis-case-report-and-review-of-8-patients-in-literature
#14
JOURNAL ARTICLE
Toshihiko Matsuo, Chie Nakago Matsuo, Nobuhiko Matsuo, Ayano Mori, Masaaki Murakami, Hiroshi Ito
Periodontal diseases are well-known background for infective endocarditis. Here, we show that pericardial effusion or pericarditis might have origin also in periodontal diseases. An 86-year-old man with well-controlled hypertension and diabetes mellitus developed asymptomatic increase in pericardial effusion. Two weeks previously, he took oral new quinolone antibiotics for a week because he had painful periodontitis along a dental bridge in the mandibular teeth on the right side and presented cheek swelling...
2024: Journal of Investigative Medicine High Impact Case Reports
https://read.qxmd.com/read/38495891/construction-of-an-aerolysin-based-multi-epitope-vaccine-against-aeromonas-hydrophila-an-in-silico-machine-learning-and-artificial-intelligence-supported-approach
#15
JOURNAL ARTICLE
Abdullah S Alawam, Maher S Alwethaynani
Aeromonas hydrophila , a gram-negative coccobacillus bacterium, can cause various infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis, skin and wound infections, meningitis, fulminating septicemia, enterocolitis, peritonitis, and endocarditis. It frequently occurs in aquatic environments and readily contacts humans, leading to high infection rates. This bacterium has exhibited resistance to numerous commercial antibiotics, and no vaccine has yet been developed. Aiming to combat the alarmingly high infection rate, this study utilizes in silico techniques to design a multi-epitope vaccine (MEV) candidate against this bacterium based on its aerolysin toxin, which is the most toxic and highly conserved virulence factor among the Aeromonas species...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38495428/mycotic-pulmonary-artery-aneurysm-a-rare-complication-of-ventricular-septal-defect-with-infective-endocarditis-a-case-report
#16
Selma Khouchoua, Lina Belkouchi, Najlaa Lrhorfi, Siham El Haddad, Nazik Allali, Latifa Chat
INTRODUCTION: Pulmonary artery aneurysms encompass a wide range of presentations and forms. Mycotic aneurysms represent a particular subset of focal dilatation of the vessel wall with high morbidity and mortality rates. Herein, we report the case of a 32 year old patient, with a prior history of ventricular septal defect presenting with a mycotic pulmonary artery aneurysm associated with infective endocarditis and septic emboli. CASE PRESENTATION: We present the case of a 32 year old male with known history of congenital ventricular septal defect presented to the emergency department with signs of sepsis and dyspnea...
2024: Clinical Medicine Insights. Case Reports
https://read.qxmd.com/read/38495425/management-of-prosthetic-mitral-valve-infective-endocarditis-in-a-patient-with-congenital-heart-disease
#17
Nadir Emre Herdan, Richard Ferraro, Francoise Adeline Marvel, Stephanie Leigh Alden, Ari Michael Cedars
We present the case of an adult patient with Kartagener's syndrome, multiple prior sternotomies, and recurrent prosthetic valve endocarditis, a scenario without clear guidelines to direct management. Ultimately, the team elected for medical management given the high mortality risk associated with surgery; the patient responded to antibiotic therapy.
May 1, 2024: JACC. Case reports
https://read.qxmd.com/read/38483553/-endocarditis-and-ischemic-stroke-of-rare-cause
#18
JOURNAL ARTICLE
L Schönfeld, G Scheumann, J Jöckel
A 60-year-old male patient presented with ischemic-embolic stroke. Transesophageal echocardiography revealed the cause to be aortic valve endocarditis with highly eccentric aortic valve regurgitation. The blood cultures taken several times remained sterile. The indication for surgical aortic valve replacement was made. Conventional microbiological work-up of the heart valve did not reveal any pathogens. The additional molecular genetic testing using eubacterial PCR ("polymerase chain reaction" [PCR]) finally demonstrated the presence of Tropheryma whipplei...
March 14, 2024: Inn Med (Heidelb)
https://read.qxmd.com/read/38482056/chiral-phthalimides-against-penicillin-binding-protein-2a-of-methicillin-resistant-staphylococcus-aureus-molecular-docking-and-in-vitro-analysis
#19
JOURNAL ARTICLE
Aamina Azam Khan, Momin Khan, Sher Wali Khan, Nayyer Siddique, Rimsha Abid, Shandana Zulfiqar, Sidra Rahman, Muhammad Ali
Staphylococcus aureus ( S. aureus ) is a commensal bacterium and an opportunistic pathogen causing a wide variety of infections ranging from localized skin and soft tissue infections to life-threatening severe bacteremia, osteomyelitis, endocarditis, atopic dermatitis, prosthetic joint infection, staphylococcal food poisoning, medical device-related infections, and pneumonia. It is attributed to an acquired resistant gene, mecA , encoding penicillin-binding protein 2a (PBP2a). PBP2a is an essential protein responsible for the resistivity of methicillin-resistant S...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38481485/endocarditis-prevention-time-for-a-review-of-nice-guidance
#20
REVIEW
Martin Thornhill, Bernard Prendergast, Mark Dayer, Ash Frisby, Larry M Baddour
UNLABELLED: In 2023, the European Society of Cardiology (ESC) updated its infective endocarditis (IE) guidelines strongly endorsing antibiotic prophylaxis (AP) before invasive dental procedures (IDPs) for high-risk patients, elevating their recommendation to Class I. The American Heart Association (AHA) is aligned with this view and reaffirmed the need for AP to prevent IE in those at high-risk in its 2021 guidelines. In contrast, the UK's National Institute for Health and Care Excellence (NICE) recommends against routine AP use...
April 2024: The Lancet regional health. Europe
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