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https://www.readbyqxmd.com/read/28928251/whipple-s-endocarditis-presenting-as-ulnar-artery-aneurysm-if-you-don-t-look-you-won-t-find
#1
Owen Seddon, Irasha Hettiarachchi
A 54-year-old female patient presented to her local district general hospital with a painful, swollen left arm. Imaging revealed an ulnar artery aneurysm. The aetiology was embolic, with an echocardiogram revealing vegetations on the aortic valve. The patient was treated empirically for 6 weeks with amoxicillin and gentamicin for endocarditis. Eight months later, she had an elective aortic valve replacement for symptomatic aortic regurgitation. The valve was culture negative but analysis by 16S rDNA PCR was positive for Tropheryma whipplei In retrospect, the ulnar artery aneurysm and a history of arthralgia were attributed to an underlying diagnosis of Whipple's endocarditis...
September 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28903607/candida-endocarditis-systematic-literature-review-from-1997-to-2014-and-analysis-of-29-cases-from-the-italian-study-of-endocarditis
#2
Simone Giuliano, Maurizio Guastalegname, Alessandro Russo, Marco Falcone, Veronica Ravasio, Marco Rizzi, Matteo Bassetti, Pierluigi Viale, Maria Bruna Pasticci, Emanuele Durante-Mangoni, Mario Venditti
Candida Endocarditis (CE) is a deadly disease. It is of paramount importance to assess risk factors for acquisition of both Candida native (NVE) and prosthetic (PVE) valve endocarditis and relate clinical features and treatment strategies with the outcome of the disease. Areas covered: We searched the literature using the Pubmed database. Cases of CE from the Italian Study on Endocarditis (SEI) were also included. Overall, 140 cases of CE were analyzed. Patients with a history of abdominal surgery and antibiotic exposure had higher probability of developing NVE than PVE...
September 14, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28889830/endocarditis-of-a-congenital-coronary-fistula-in-a-child
#3
Thomas Krasemann, Ingrid M van Beynum, Ingrid M E Frohn-Mulder, Michiel Dalinghaus
Endocarditis of congenital coronary fistulas in the cardiac chambers is rare, especially in the paediatric age group. We describe the case of a 9-year-old boy with a fistula from the dilated right coronary artery to the junction of the superior caval vein to the right atrium, complicated by endocarditis. Treatment consisted of 6 weeks of antibiotics and interventional closure of the fistula 3 months later with an Amplatzer vascular plug.
September 11, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28889756/occurrence-of-vancomycin-resistant-staphylococcus-aureus-in-the-oral-cavity-of-patients-with-dental-caries
#4
Sajith Vellappally, Darshan Devang Divakar, Abdulaziz Abdullah Al Kheraif, Ravikumar Ramakrishnaiah, Amer Alqahtani, M H N Dalati, Sukumaran Anil, Aftab Ahmed Khan, P R Harikrishna Varma
Oral streptococci are the major group of microbes isolated from oral microflora. They represent frequent pathogens of infective endocarditis (IE), and it is assumed that in most of the cases oral streptococci are acquired via mucosa layer of oral cavity. Staphylococcus aureus is also frequently isolated from IE as it accounts for 20%-30% of all cases. Vancomycin has been the most reliable therapeutic agent against infections caused by methicillin-resistant S. aureus (MRSA). The main objective of this study was to examine the occurrence of S...
September 11, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28886792/antibiotic-prophylaxis-probably-reduces-the-risk-of-developing-bacteremia-in-patients-at-risk-of-developing-infective-endocarditis-who-are-undergoing-dental-extractions
#5
Romina Brignardello-Petersen
No abstract text is available yet for this article.
September 3, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28882817/dental-procedures-antibiotic-prophylaxis-and-endocarditis-among-people-with-prosthetic-heart-valves-nationwide-population-based-cohort-and-a-case-crossover-study
#6
Sarah Tubiana, Pierre-Olivier Blotière, Bruno Hoen, Philippe Lesclous, Sarah Millot, Jérémie Rudant, Alain Weill, Joel Coste, François Alla, Xavier Duval
Objective To assess the relation between invasive dental procedures and infective endocarditis associated with oral streptococci among people with prosthetic heart valves.Design Nationwide population based cohort and a case crossover study.Setting French national health insurance administrative data linked with the national hospital discharge database.Participants All adults aged more than 18 years, living in France, with medical procedure codes for positioning or replacement of prosthetic heart valves between July 2008 and July 2014...
September 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28882816/do-patients-at-risk-of-infective-endocarditis-need-antibiotics-before-dental-procedures
#7
Thomas J Cahill, Mark Dayer, Bernard Prendergast, Martin Thornhill
No abstract text is available yet for this article.
September 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28877714/successful-medical-management-of-a-case-of-austrian-syndrome-an-uncommon-entity-in-the-modern-antibiotic-era-a-case-report
#8
Muhammad Abdur Rahim, Shahana Zaman, Hasna Fahmima Haque, Samira Rahat Afroze, Khwaja Nazim Uddin
BACKGROUND: Austrian syndrome-the combination of meningitis, pneumonia and infective endocarditis due to Streptococcus pneumoniae infection, is a rare entity. In literature only a few hundreds of cases are reported but surprisingly we did not find any report on Austrian syndrome in or from Bangladesh. CASE PRESENTATION: We report the case history of a middle aged Bangladeshi diabetic man, who had fever, cough, shortness of breath and altered mentation. He had tachycardia, bi-basal lung crepitations, new cardiac murmurs and meningism...
September 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28874131/a-chronic-hemodialysis-patient-with-isolated-pulmonary-valve-infective-endocarditis-caused-by-non-albicans-candida-a-rare-case-and-literature-review
#9
Chih-Hao Chang, Myo-Ming Huang, Dong-Feng Yeih, Kuo-Cheng Lu, Yi-Chou Hou
BACKGROUND: Isolated pulmonary valve infective endocarditis caused by Candida is rare in chronic hemodialysis patients. The 2009 Infectious Diseases Society of America guidelines suggest the combined use of surgery and antibiotics to treat candidiasis; however, successful nonsurgical treatment of Candida endocarditis has been reported. CASE PRESENTATION: A 63-year-old woman with end-stage kidney disease was admitted to our hospital after experiencing disorientation for 5 days...
September 6, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28873268/a-novel-in-vitro-model-for-hematogenous-spreading-of-s-aureus-device-biofilms-demonstrating-clumping-dispersal-as-an-advantageous-dissemination-mechanism
#10
R B Grønnemose, K L Saederup, H J Kolmos, S W K Hansen, C A Asferg, K J Rasmussen, Y Palarasah, T E Andersen
Staphylococcus aureus is able to disseminate from vascular device biofilms to the blood and organs, resulting in life-threatening infections such as endocarditis. The mechanisms behind spreading are largely unknown, especially how the bacterium escapes immune effectors and antibiotics in the process. Using an in vitro catheter infection model, we studied S. aureus biofilm growth, late-stage dispersal, and reattachment to downstream endothelial cell layers. The ability of the released biofilm material to resist host response and disseminate in vivo was furthermore studied in whole blood- and phagocyte survival assays, and in a short-term murine infection model...
September 5, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/28873140/association-of-evidence-based-care-processes-with-mortality-in-staphylococcus-aureus-bacteremia-at-veterans-health-administration-hospitals-2003-2014
#11
Michihiko Goto, Marin L Schweizer, Mary S Vaughan-Sarrazin, Eli N Perencevich, Daniel J Livorsi, Daniel J Diekema, Kelly K Richardson, Brice F Beck, Bruce Alexander, Michael E Ohl
Importance: Staphylococcus aureus bacteremia is common and frequently associated with poor outcomes. Evidence indicates that specific care processes are associated with improved outcomes for patients with S aureus bacteremia, including appropriate antibiotic prescribing, use of echocardiography to identify endocarditis, and consultation with infectious diseases (ID) specialists. Whether use of these care processes has increased in routine care for S aureus bacteremia or whether use of these processes has led to large-scale improvements in survival is unknown...
September 5, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28868768/antibiotic-prophylaxis-for-infective-endocarditis-a-systematic-review-and-meta-analysis
#12
David Isaacs
No abstract text is available yet for this article.
September 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28865816/bacteremia-associated-with-oral-surgery-a%C3%A2-review
#13
REVIEW
Beatriz González Navarro, Enric Jané Salas, Albert Estrugo Devesa, José López López, Miguel Viñas
OBJECTIVES: Bacterial (infective) endocarditis, a microbial infection of the endocardium surfaces after bacteremia, causes significant morbidity and mortality. Recent epidemiologic studies have reported a prevalence of 2-8 cases per 100,000 individuals per year, with the highest incidence in those aged 70-80 years and those living in developed countries. We systematically reviewed the literature on several critical aspects regarding the development of bacteremia after oral surgery. The purpose of this work is to assess the controversy regarding antibiotic prophylaxis before oral surgery...
September 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28859349/from-expert-protocols-to-standardized-management-of-infectious-diseases
#14
Jean-Christophe Lagier, Camille Aubry, Marion Delord, Pierre Michelet, Hervé Tissot-Dupont, Matthieu Million, Philippe Brouqui, Didier Raoult, Philippe Parola
We report here 4 examples of management of infectious diseases (IDs) at the University Hospital Institute Méditerranée Infection in Marseille, France, to illustrate the value of expert protocols feeding standardized management of IDs. First, we describe our experience on Q fever and Tropheryma whipplei infection management based on in vitro data and clinical outcome. Second, we describe our management-based approach for the treatment of infective endocarditis, leading to a strong reduction of mortality rate...
August 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28855980/pseudomonas-endocarditis-with-an-unstable-phenotype-the-challenges-of-isolate-characterization-and-carbapenem-stewardship-with-a-partial-review-of-the-literature
#15
Emil Lesho, Erik Snesrud, Yoon Kwak, Ana Ong, Rosslyn Maybank, Maryrose Laguio-Vila, Ann R Falsey, Mary Hinkle
BACKGROUND: Pseudomonas endocarditis is exceedingly rare, especially in patients without predisposing risks. We present such a case that included unexpected switches in antibacterial resistance profiles in two Pseudomonas aeruginosa (PA) strains with the same whole-genome sequence. The case also involved diagnostic and treatment challenges, such as issues with automated testing platforms, choosing the optimal aminoglycoside, minimizing unnecessary carbapenem exposure, and the need for faster, more informative laboratory tests...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28846153/international-survey-of-knowledge-attitudes-and-practices-of-cardiologists-regarding-prevention-and-management-of-cardiac-implantable-electronic-device-infections
#16
Daniel C DeSimone, Anwar A Chahal, Christopher V DeSimone, Samuel J Asirvatham, Paul A Friedman, Larry M Baddour, M Rizwan Sohail
BACKGROUND: Cardiovascular implantable electronic devices (CIEDs) can be life-saving. However, complications from CIED infection can be life-threatening often requiring device removal. Despite publication of CIED infection management guidelines there remains marked variation in clinical practice. OBJECTIVE: To better understand and quantify these differences, we conducted a multi-national survey of practitioners of CIED management. METHODS: An electronic survey was sent to Heart Rhythm Society members, spanning 70 countries across six continents...
August 28, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28838446/a-case-report-organs-from-a-donor-with-highly-virulent-zoonotic-outbreak-strain-of-streptococcus-agalactiae-serotype-iii-multilocus-sequence-type-283-infective-endocarditis-did-not-result-in-transmission-with-adequate-prophylactic-antibiotic-cover
#17
J Sim, T T Tan, L Wijaya, H K Sran, S Thangaraju, T Kee
In 2015, an outbreak involving a highly virulent zoonotic outbreak strain of Streptococcus agalactiae serotype III, multilocus sequence type 283 occurred in Singapore with increased neurologic complications, septic arthritis, and spinal infections in healthier patients. We report a case of a successful dual kidney transplant from a deceased donor with infective endocarditis and disseminated infection with the same strain of S agalactiae and we review the current literature.
September 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28811093/risk-factors-for-infective-endocarditis-in-children-with-congenital-heart-diseases-a-nationwide-population-based-case-control-study
#18
Li-Chuan Sun, Chih-Cheng Lai, Cheng-Yi Wang, Ya-Hui Wang, Jen-Yu Wang, Yo-Ling Hsu, Yin-Lan Hu, En-Ting Wu, Ming-Tai Lin, Leticia B Sy, Likwang Chen
BACKGROUND: Infective endocarditis (IE) is uncommon in childhood. Its associated epidemiological characteristics in patients with congenital heart disease (CHD) remain unclear. METHODS: The study population included children born in Taiwan during the years 1997 to 2005 who were diagnosed as having CHD before 3years of age. All children were followed up until the end year of 2010, the diagnosis of infective endocarditis, or death. The demographic characteristics of patients with and without IE, the invasive procedures performed during 6months before the index date, the prophylactic antibiotics related to dental procedures, and in-hospital mortality were collected...
December 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28807042/incidence-prevalence-and-management-of-mrsa-bacteremia-across-patient-populations-a-review-of-recent-developments-in-mrsa-management-and-treatment
#19
REVIEW
Ali Hassoun, Peter K Linden, Bruce Friedman
Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of morbidity and mortality and can cause metastatic or complicated infections such as infective endocarditis or sepsis. MRSA is responsible for most global S. aureus bacteremia cases, and compared with methicillin-sensitive S. aureus, MRSA infection is associated with poorer clinical outcomes. S. aureus virulence is affected by the unique combination of toxin and immune-modulatory gene products, which may differ by geographic location and healthcare- or community-associated acquisition...
August 14, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28775090/missed-aortic-valve-endocarditis-resulting-in-complete-atrioventricular-block-and-redo-mechanical-valve-replacement
#20
Amer Harky, Megan Garner, Miruna Popa, Alex Shipolini
Infective endocarditis is a rare disease associated with high morbidity and mortality. As a result, early diagnosis and prompt antibiotic treatment with or without surgical intervention is crucial in the management of such condition.We report a case of missed infective endocarditis of the aortic valve. The patient underwent mechanical aortic valve replacement, with the native valve being sent for histopathological examination. On re-admission 16 months later, he presented with syncope, shortness of breathing and complete heart block...
August 3, 2017: BMJ Case Reports
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