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Placental thickness

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https://www.readbyqxmd.com/read/29193660/preterm-birth-with-placental-evidence-of-malperfusion-is-associated-with-cardiovascular-risk-factors-after-pregnancy-a-prospective-cohort-study
#1
Janet M Catov, Matthew F Muldoon, Steven E Reis, Roberta B Ness, Lananh N Nguyen, Jose-Miguel Yamal, Hyunsoo Hwang, W Tony Parks
OBJECTIVE: Preterm birth (PTB) is associated with excess maternal cardiovascular disease risk. We considered that women with PTB and placental evidence of maternal malperfusion would be particularly affected. DESIGN: Pregnancy cohort study. SETTING: Pittsburgh Pennsylvania, US. POPULATION: Women with PTB (n=115) and term births (n=210) evaluated 4-12 years after pregnancy. METHODS: Cardiometabolic risk markers were compared in women with prior PTB vs...
November 28, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29169625/ovarian-embryonal-carcinoma-in-a-dog
#2
B Banco, R Ferrari, D Stefanello, D Groppetti, A Pecile, S Faverzani, M Longo, D D Zani, G Ravasio, M Caniatti, V Grieco
A 17-month-old female doberman pinscher was referred for an abdominal mass and ascites. Exploratory laparotomy revealed the presence of a large neoplastic mass replacing the right ovary and associated with multiple mesovarian, mesometrial and peritoneal nodules. An ovariohysterectomy was performed. Grossly, the tumour was soft and multilocular with large areas of haemorrhage and necrosis. Microscopically, it was infiltrative and composed of round and polygonal cells arranged respectively in solid sheets or forming distorted tubular structures separated by thick fibrovascular septae...
November 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/29156171/the-use-of-decellularized-human-placenta-in-full-thickness-wound-repair-and%C3%A2-periarticular-soft-tissue-reconstruction-an-update-on-regenerative-healing
#3
REVIEW
Stephen A Brigido, Scott C Carrington, Nicole M Protzman
Prolonged or incomplete healing of the foot and ankle can pose significant challenges. Therefore, investigators have begun searching for alternative treatment strategies. With advances in tissue engineering, decellularized human placental connective tissue matrix has been suggested as a means to achieve more rapid and complete healing for various soft tissue and bone procedures. Basic science and clinical studies have shown that decellularized human placental connective tissue matrix can support regenerative healing through cellular migration, accelerated tissue remodeling, and the establishment of functional tissue...
January 2018: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/29125114/antenatal-sonographic-diagnosis-and-clinical-significance-of-placenta-previa-accreta-after-cesarean-section
#4
Zhen-Zhen Liu, Yao Wei, Ruo-Jiao Wang, Wen Xu, Zhi-Min Shi, Qing Dai
Objective To investigate the clinical and antenatal sonographic characteristics of placenta previa accreta after cesarean section. Methods The data of 21 inpatients diagnosed as placenta previa accreta after cesarean section in PUMC Hospital from 2006 to 2016 were retrospectively reviewed. The clinical and ultrasound features were recorded and compared among three placental accreta groups,including placenta accrete group(n=5),increta group(n=12),and percreta group(n=4). The relationship between the placental thickness at the uterine anterior lower segment level and the blood loss of the following cesarean section was tested...
October 30, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29079565/essentiality-of-regulator-of-g-protein-signaling-6-and-oxidized-ca-2-calmodulin-dependent-protein-kinase-ii-in-notch-signaling-and%C3%A2-cardiovascular-development
#5
Bandana Chakravarti, Jianqi Yang, Katelin E Ahlers-Dannen, Zili Luo, Heather A Flaherty, David K Meyerholz, Mark E Anderson, Rory A Fisher
BACKGROUND: Congenital heart defects are the most common birth defects worldwide. Although defective Notch signaling is the major cause of mouse embryonic death from cardiovascular defects, how Notch signaling is regulated during embryonic vasculogenesis and heart development is poorly understood. METHODS AND RESULTS: Regulator of G protein signaling 6 (RGS6)(-/-)/Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)(VV) double mutant mice were developed by crossing RGS6(-/-) mice with mice expressing an oxidation-resistant CaMKIIδ (CaMKII(VV)), and the resulting embryonic defects/lethality were investigated using E7...
October 27, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29069339/is-placental-malaria-a-long-term-risk-factor-for-mild-malaria-attack-in-infancy-revisiting-a-paradigm
#6
Olivier Bouaziz, David Courtin, Gilles Cottrell, Jacqueline Milet, Gregory Nuel, André Garcia
Background: Children born to mothers with placental malaria (PM) have been described as more susceptible to the occurrence of a first malaria infection. However, whether or not these children remain more at risk during infancy has never been explored. We aimed to determine if children born to mothers with PM are more susceptible to malaria and remain at higher risk between birth and 18 months. Methods: 550 children were weekly followed-up with control of temperature and, if >37...
October 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29046476/tracking-mesenchymal-stem-cell-contributions-to-regeneration-in-an-immunocompetent-cartilage-regeneration-model
#7
Daniela Zwolanek, María Satué, Verena Proell, José R Godoy, Kathrin I Odörfer, Magdalena Flicker, Sigrid C Hoffmann, Thomas Rülicke, Reinhold G Erben
It is currently controversially discussed whether mesenchymal stem cells (MSC) facilitate cartilage regeneration in vivo by a progenitor- or a nonprogenitor-mediated mechanism. Here, we describe a potentially novel unbiased in vivo cell tracking system based on transgenic donor and corresponding immunocompetent marker-tolerant recipient mouse and rat lines in inbred genetic backgrounds. Tolerance of recipients was achieved by transgenic expression of an immunologically neutral but physicochemically distinguishable variant of the marker human placental alkaline phosphatase (ALPP)...
October 19, 2017: JCI Insight
https://www.readbyqxmd.com/read/29044348/sonographically-abnormal-placenta-an-association-with-an-increased-risk-poor-pregnancy-outcomes
#8
W D Wan Masliza, M Y Bajuri, M R Hassan, N M Naim, A Shuhaila, S Das
BACKGROUND: The placenta is a most interesting but unfortunately often ignored and misunderstood organ. Placental abnormalities, therefore, can be an "early warning system" for fetal problems. A complete prenatal sonographic examination of the placenta is an essential component as its abnormalities can have a direct effect on fetal or maternal outcomes, obstetrical management and future fertility. OBJECTIVE: To determine whether any association exists between the finding of an increased thickness of placenta, abnormal placenta shape, placental calcification, placental lake and abnormal cord insertion site at 20-22 and 30-32 weeks gestation with an increased risk of uteroplacental complications or a poor pregnancy outcome...
September 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29038043/laparoscopic-excision-of-a-scar-pregnancy-and-isthmocele-repair
#9
Huseyin Kiyak, Lale Susan Wetherilt, Kerem Doga Seckin, Ibrahim Polat, Pınar Kadirogullari, Tolga Karacan
Laparoscopic excision of a scar pregnancy and isthmocele repair with barbed suture Design Step by step explanation of the laparoscopic excision technique of a scar pregnancy and isthmocele repair Setting Cesarean scar pregnancy occurs as a result of attachment of the products of conception to the uterine scar. In the present case, a 34 year old G4 P1 patient with a history of one miscarriage and one ectopic pregnancy was diagnosed with type 2 cesarean scar pregnancy at 7 weeks of gestation. A Dilation & Curretage was performed at the 8th week of gestation to terminate the pregnancy...
October 13, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29028488/prenatal-phthalate-exposure-and-placental-size-and-shape-at-birth-a-birth-cohort-study
#10
Yuan-Duo Zhu, Hui Gao, Kun Huang, Yun-Wei Zhang, Xiu-Xiu Cai, Hui-Yuan Yao, Lei-Jing Mao, Xing Ge, Shan-Shan Zhou, Yuan-Yuan Xu, Zhong-Xiu Jin, Jie Sheng, Shuang-Qin Yan, Wei-Jun Pan, Jia-Hu Hao, Peng Zhu, Fang-Biao Tao
OBJECTIVE: There is concern over the potential placental effects of prenatal phthalate exposure, and the potential adverse effects of prenatal phthalate exposure require further study; however, few data are available in humans. We investigated the associations between phthalate exposure in each trimester and both placental size and shape at birth. METHODS: We measured the urinary concentrations of phthalate metabolites among 2725 pregnant women in the Ma'anshan Birth Cohort...
October 10, 2017: Environmental Research
https://www.readbyqxmd.com/read/28992508/il-37-and-38-signalling-in-gestational-diabetes
#11
Zhiyan Yu, Jun Liu, Rui Zhang, Xinmei Huang, Tiange Sun, Yueyue Wu, Brett D Hambly, Shisan Bao
Gestational diabetes mellitus (GDM) is still a clinical challenge around world. Inflammation contributes to the pathogenesis of GDM, the precise underlying mechanism remains to be explored. IL-37 and 38 play important role in autoimmunity, but their role in the development of GDM is unclear. Using histopathology and immunohistochemistry, the thickness of the umbilical artery, the area of capillaries within the placental chorionic villi, and the production of IL-37/38 were determined. Placental mRNA of IL-37/IL-38 from GDM and Non-GMD was measured using qRT-PCR...
September 28, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/28967076/aflibercept-in-the-management-of-acute-retinal-necrosis-syndrome-related-macular-edema
#12
Leticia Ortega-Evangelio, Javier Navarrete-Sanchis, Basil K Williams, Juan Miguel Tomás-Torrent
PURPOSE: Acute retinal necrosis (ARN) is a panuveitis syndrome that may lead to severe complications such as cystoid macular edema (CME). There is no consensus about the best treatment. We report one case of CME secondary to ARN managed with intravitreal aflibercept. CASE REPORT: A 41-year-old woman with a history of successfully treated varicella-zoster virus-associated ARN developed an epiretinal membrane (ERM) and underwent pars plana vitrectomy, ERM removal, inner limiting membrane peel, and lensectomy...
September 14, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28934247/the-extent-of-intrauterine-growth-restriction-determines-the-severity-of-cerebral-injury-and-neurobehavioural-deficits-in-rodents
#13
Crystal A Ruff, Stuart D Faulkner, Prakasham Rumajogee, Stephanie Beldick, Warren Foltz, Jennifer Corrigan, Alfred Basilious, Shangjun Jiang, Shanojan Thiyagalingam, Jerome Y Yager, Michael G Fehlings
BACKGROUND: Cerebral Palsy (CP) is the most common physical pediatric neurodevelopmental disorder and spastic diplegic injury is its most frequent subtype. CP results in substantial neuromotor and cognitive impairments that have significant socioeconomic impact. Despite this, its underlying pathophysiological mechanisms and etiology remain incompletely understood. Furthermore, there is a need for clinically relevant injury models, which a) reflect the heterogeneity of the condition and b) can be used to evaluate new translational therapies...
2017: PloS One
https://www.readbyqxmd.com/read/28883908/increased-levels-of-oxidative-stress-markers-soluble-cd40-ligand-and-carotid-intima-media-thickness-reflect-acceleration-of-atherosclerosis-in-male-patients-with-ankylosing-spondylitis-in-active-phase-and-without-the-classical-cardiovascular-risk-factors
#14
Agata Stanek, Armand Cholewka, Tomasz Wielkoszyński, Ewa Romuk, Karolina Sieroń, Aleksander Sieroń
OBJECTIVE: The primary aim of the study was to assess levels of oxidative stress markers, soluble CD40 ligand (sCD40L), serum pregnancy-associated plasma protein-A (PAPP-A), and placental growth factor (PlGF) as well as carotid intima-media thickness (IMT) in patients with ankylosing spondylitis (AS) with active phase without concomitant classical cardiovascular risk factors. MATERIAL AND METHODS: The observational study involved 96 male subjects: 48 AS patients and 48 healthy ones, who did not differ significantly regarding age, BMI, comorbid disorders, and distribution of classical cardiovascular risk factors...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28864000/first-trimester-placental-thickness-and-the-risk-of-preeclampsia-or-sga
#15
Chantale Vachon-Marceau, Suzanne Demers, Stéphanie Markey, Nan Okun, Mario Girard, John Kingdom, Emmanuel Bujold
INTRODUCTION: Placental thickness in the second trimester of pregnancy has been associated with risks of placenta-mediated complications of pregnancy. We aimed to estimate the association between first-trimester maximum placental thickness and the subsequent risk of preeclampsia and/or the delivery of small-for-gestational-age (SGA) neonate. METHODS: Prospective cohort study of women recruited at 11-14 weeks gestation. Placental thickness was measured at its apparent center and reported in multiple of median (MoM) adjusted for gestational age...
September 2017: Placenta
https://www.readbyqxmd.com/read/28833750/first-trimester-detection-of-abnormally-invasive-placenta-in-women-at-risk-a-systematic-review-and-meta-analysis
#16
REVIEW
Francesco D'Antonio, Ilan E Timor-Trisch, Josè Palacios-Jaraquemada, Ana Monteagudo, Danilo Buca, Francesco Forlani, Gabriella Minneci, Francesca Foti, Lamberto Manzoli, Marco Liberati, Ganesh Acharya, Giuseppe Calì
OBJECTIVES: The primary aim of this systematic review was to ascertain whether ultrasound (US) signs suggestive of abnormally invasive placenta (AIP) are present in the first trimester. The secondary aims were to ascertain the strength of association and the predictive accuracy of such signs in detecting AIP in the first trimester of pregnancy. METHODS: MEDLINE, EMBASE, CINAHL and Cochrane databases (2000-2016) were searched. Only studies reporting the first trimester diagnosis of AIP that was subsequently confirmed in the third trimester either during operative delivery or by pathology were included...
August 21, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28826360/placental-location-postpartum-hemorrhage-and-retained-placenta-in-women-with-a-previous-cesarean-section-delivery-a-prospective-cohort-study
#17
Johanna Belachew, Karin Eurenius, Ajlana Mulic-Lutvica, Ove Axelsson
OBJECTIVE: Women previously giving birth with cesarean section have an increased risk of postpartum hemorrhage (PPH) and retained placenta. The objective of this study was to determine if anterior placental location increased the risk of PPH and retained placenta in such women. MATERIALS AND METHODS: We performed a prospective cohort study on 400 women with cesarean section delivery in a previous pregnancy. Ultrasound examinations were performed at gestational week 28-30, and placental location, myometrial thickness, and three-dimensional vascularization index (VI) were recorded...
August 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28797201/meconium-staining-of-the-amniotic-fluid-and-the-presence-and-severity-of-acute-placental-inflammation-a-study-of-term-deliveries-in-a-predominantly-african-american-population
#18
Haleema Saeed, Suzanne M Jacques, Faisal Qureshi
OBJECTIVE: To determine frequency, stage and grade of placental histologic acute maternal inflammatory response (MIR) and fetal inflammatory response (FIR) in meconium-stained amniotic fluid (MSAF) in our predominantly African-American population. METHODS: Term placentas with MSAF (n = 310) were evaluated for MIR/FIR, including stage/grade, and compared with placentas with clear amniotic fluid (AF) (n = 250). MIR/FIR were also evaluated in thick compared to thin MSAF subgroups...
August 23, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28793392/placental-lesions-in-meconium-aspiration-syndrome
#19
Binnari Kim, Soo-Young Oh, Jung-Sun Kim
BACKGROUND: Meconium aspiration syndrome (MAS) is defined by respiratory distress requiring supplemental oxygen in a meconium-stained neonate. MAS is clinically subclassified as mild, moderate, and severe according to the oxygen requirement. The aims of this study were to compare the histological findings in the placentas of MAS neonates with those of meconium-stained but non-MAS neonates and to analyze the correlation between the severity of MAS and the grade of its histological parameters...
September 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28752144/is-there-any-relationship-between-low-papp-a-levels-and-measures-of-umbilical-vein-and-placental-thickness-during-first-trimester-of-pregnancy
#20
Gulsum Uysal, Sadan Tutus, Fulya Cagli, Cevdet Adiguzel
OBJECTIVE: Low pregnancy-associated plasma protein A (PAPP-A) level is associated with adverse perinatal outcomes. The purpose of this study was to evaluate relationship between umbilical cord diameter (UCD), umbilical vein and artery diameters (UVD, UAD), placental thickness, and PAPP-A level at gestational age of between 11 and 14 weeks. METHODS: UCD, UVD, UAD, and placental thickness of 246 women were assessed during ultrasound examination at between 11 and 14 weeks of gestation, as well as measurement of nuchal translucency (NT) and crown-rump length (CRL)...
2017: Northern Clinics of Istanbul
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