Read by QxMD icon Read

Placental thickness

Ignatia F Reijnders, Annemarie G M G J Mulders, Melissa van der Windt, Eric A P Steegers, Régine P M Steegers-Theunissen
BACKGROUND: Worldwide, placenta-related complications contribute to adverse pregnancy outcomes, such as pre-eclampsia, fetal growth restriction and preterm birth, with implications for the future health of mothers and offspring. The placenta develops in the periconception period and forms the interface between mother and embryo/fetus. An unhealthy periconceptional maternal lifestyle, such as smoking, alcohol and under- and over-nutrition, can detrimentally influence placental development and function...
November 8, 2018: Human Reproduction Update
John P McQuilling, Mitchell Sanders, Lindsay Poland, Mia Sanders, Giacomo Basadonna, Norman E Waldrop, Katie C Mowry
INTRODUCTION: Healing of tendon injuries is often plagued by significant scar formation and compromised biomechanical function. For those with diabetes, these injuries are further complicated by alterations to the extracellular matrix of the tendon, poor circulation, and delayed wound healing; consequently, complications and re-rupture rates for patients with diabetes are reported higher than the typical patient population. Placental derived membranes, specifically dehydrated human amnion/chorion membranes (dACMs), have been utilized clinically as an adhesion barrier, and these membranes have been shown to reduce scarring and aid in tissue repair...
October 26, 2018: Wounds: a Compendium of Clinical Research and Practice
Luca Di Antonio, Lisa Toto, Alessandra Mastropasqua, Lorenza Brescia, Emanuele Erroi, Alessia Lamolinara, Marta Di Nicola, Leonardo Mastropasqua
The aim of the study was to assess retinal vascular changes using optical coherence tomography angiography (OCTA) and aqueous humour changes of vascular endothelial growth factor (VEGF) and placental growth factor (PIGF) levels in treatment-naïve myopic choroidal neovascularization (mCNV) after aflibercept intravitreal injection. To explore the correlation between clinical and laboratory parameters. Fifteen eyes of 15 patients with treatment-naïve mCNV underwent 2 intravitreal injections of aflibercept. Main outcome measures were best corrected visual acuity (BCVA), central retinal thickness (CRT) and external limiting membrane (ELM) visualization at OCT, lesion area and leakage at fluorescein angiography (FA), OCTA flow area and selected area at baseline and after the injections...
October 23, 2018: Scientific Reports
Khatia Nanobashvili, Chauntelle Jack-Roberts, Rachel Bretter, Naudia Jones, Kathleen Axen, Anjana Saxena, Kali Blain, Xinyin Jiang
Gestational diabetes mellitus (GDM) is characterized by excessive placental fat and glucose transport, resulting in fetal overgrowth. Earlier we demonstrated that maternal choline supplementation normalizes fetal growth in GDM mice at mid-gestation. In this study, we further assess how choline and its oxidation product betaine influence determinants of placental nutrient transport in GDM mice and human trophoblasts. C57BL/6J mice were fed a high-fat (HF) diet 4 weeks prior to and during pregnancy to induce GDM or fed a control normal fat (NF) diet...
October 15, 2018: Nutrients
Pear Pongsachareonnont, Michael Ying Kit Mak, Cameron Paul Hurst, Wai-Ching Lam
Purpose: To determine the levels of interleukin (IL)-6, vascular endothelial growth factor-A, platelet-derived growth factor, placental growth factor (PLGF), and other cytokines in the aqueous fluid of patients with neovascular age-related macular degeneration who respond poorly to ranibizumab. Patients and methods: This is an observational, prospective study. Thirty-two eyes from 30 patients were included in the study: 11 patients who responded poorly to ranibizumab and were switched to aflibercept (AF group), 8 patients who received ranibizumab and photodynamic therapy (PDT group), and 13 patients who responded to ranibizumab (control group)...
2018: Clinical Ophthalmology
Moses M Obimbo, Yan Zhou, Michael T Mcmaster, Craig R Cohen, Zahida Qureshi, John Ong'ech, Julius A Ogeng'o, Susan J Fisher
BACKGROUND: Preterm birth (PTB) is a major cause of infant morbidity and mortality in developing countries. Recent data suggest that in addition to HIV infection, use of antiretroviral therapy (ART) increases the risk of PTB. As the mechanisms remain unexplored, we conducted this study to determine if HIV and ART were associated with placental changes that could contribute to PTB. SETTING: We collected and evaluated placentas from 38 HIV-positive women on ART and 43 HIV-negative women who had preterm deliveries in Nairobi, Kenya...
September 27, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Kashika Nagpal, Pratima Mittal, Shabnam Bhandari Grover
Background Information: Placenta is the connecting organ between the mother and the fetus. It supplies oxygen and all the necessary elements for the growth and development of the fetus. In normal pregnancy, the growth of the placenta remains concordant with the growth of the fetus. The sonographic assessment of placenta can give information about the nutritional status of the fetus. It is known that normal placental thickness approximately equals gestational age. It is historically documented that placental weight is one-fifth of the fetal weight and abnormally thin or thick placenta is associated with increased incidence of perinatal morbidity and mortality...
October 2018: Journal of Obstetrics and Gynaecology of India
Arianna Laoreti, Basky Thilaganathan, Andrea Kaelin Agten, Aris Papageorghiou, Asma Khalil, James Uprichard, Edwin Chandraharan, Amarnath Bhide
No abstract text is available yet for this article.
September 15, 2018: Acta Obstetricia et Gynecologica Scandinavica
Shui-Hua Zhang, Jia-Yun Zhang, Jing Zhang, Wen-Li Chen, Quan Zhou
OBJECTIVE: To study the potential application of magnetic resonance imaging (MRI) for classification of retained placental tissue (RPT) in the uterus postnatally. METHODS: Twenty-two patients with clinically or pathologically proven RPT were studied. RESULTS: The thickness ratio (D1/D2) of invaded (D1) to normal (D2) myometrium could be categorized into 3 groups (>0.6, 0.1-0.6, and <0.1) correlating with the 3 types of RPT: accreta vera (RPA), increta (RPI), and percreta (RPP) (r = -0...
September 10, 2018: Journal of Computer Assisted Tomography
Brian M Burns, Stefan Hiendleder, Alan R Laing, Geoffry Fordyce, Andy D Herring
The placenta is a major driver of prenatal growth and involved in programming of postnatal performance. We therefore determined placental and embryo-fetal ultrasonographic parameters in early pregnancy and their relationships with birth weight and postnatal weights in a Bos indicus-Bos taurus composite beef cattle population. Pregnancies were generated in 2-yr-old Droughtmaster heifers by artificial insemination after estrus synchronization in 2 consecutive years (2009, n = 36 and 2010, n = 57), with a subset of 2010 heifers used again as lactating 3-yr-old cows in 2011 (n = 24)...
September 29, 2018: Journal of Animal Science
Melina Rodero Marques, Carlos Grandi, Lígia Moschen de Paula Nascente, Ricardo Carvalho Cavalli, Viviane Cunha Cardoso
OBJECTIVE: To assess the placental morphometry in pregnancies with hypertensive disorders of pregnancy (HDP) and its relationship with birth weight (BW). STUDY DESIGN: Cohort study of placental morphometry and fetal outcomes of 954 pregnancies at a university hospital in Ribeirão Preto, São Paulo, Brazil, in 2010. HDP categories were: chronic (CH), gestational (GH), preeclampsia (PRE) and pre-eclampsia superimposed on chronic hypertension (CH + PRE). Associations between BW and placental measures (PM) in pregnancies were evaluated by multiple linear regression analyses...
July 2018: Pregnancy Hypertension
Galia Oron, Liran Hiersch, Shiran Rona, Roni Prag-Rosenberg, Onit Sapir, Maya Tuttnauer-Hamburger, Yoel Shufaro, Benjamin Fisch, Avi Ben-Haroush
RESEARCH QUESTION: Does endometrial thickness affect the occurrence of obstetric complications in fresh IVF cycles? DESIGN: We conducted a retrospective cohort study that included all singleton deliveries resulting from fresh embryo transfers in a single centre between 2008 and 2014. Obstetric complications, i.e. preeclampsia, placental abruption, placenta previa, small for gestational age and preterm delivery, in singleton live births were compared among patients with an endometrial thickness of less than 7...
September 2018: Reproductive Biomedicine Online
Bo Y Park, Dawn P Misra, John Moye, Richard K Miller, Lisa Croen, M Dani Fallin, Cheryl Walker, Craig J Newschaffer, Caroline M Salafia
A growing body of evidence suggests that prenatal environment is important in Autism Spectrum Disorder (ASD) etiology. In this study, we compare placental shape features in younger siblings of children with ASD, who themselves are at high ASD risk, to a sample of low risk peers. Digital photographs of the fetal placenta surface and of the sliced placental disk from 129 high ASD risk newborns and from 267 newborns in the National Children's Study Vanguard pilot were analysed to extract comparable measures of placental chorionic surface shape, umbilical cord displacement and disk thickness...
2018: PloS One
Hironori Takahashi, Shigeki Matsubara
No abstract text is available yet for this article.
August 21, 2018: Acta Obstetricia et Gynecologica Scandinavica
Evrim Bostancı, Cetin Kılıccı, Enis Özkaya, Cigdem Abide Yayla, Ezgi Darıcı, Gamze Berkel, Mustafa Eroglu, Canan Kabaca Kocakusak
OBJECTIVE: We aimed to assess the predictive values of individual sonographic findings of abnormal placentation to determine the candidates for segmental resection Study design: This was a retrospective review of 43 pregnancies with at least one prior cesarean delivery who received an ultrasound diagnosis of placenta previa or low-lying placenta with suspected abnormal placentation in the third trimester at our institution from 2015 through 2017. Sonographic images were reviewed by an investigator blinded to pregnancy outcome...
September 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
Tayyaba Gul Malik, Syed Shoaib Ahmed, Roquyya Gul, Muhammad Khalil, Abrar Ahmed Malik, Masoom Khan
Background/aim: This study evaluates diabetic macular-edema (DME) patients for the effect of intravitreal bevacizumab (IVB) injection on macular thickness and proangiogenic biomarkers in serum and vitreous. Materials and methods: Forty DME patients were analyzed for macular thickness (MT). Twelve proangiogenic biomarkers in serum and vitreous were analyzed before and after IVB. Results: Significant decrease in MT with vitreal vascular endothelial growth factor-A (VEGF-A) was observed as expected after IVB, while serum VEGF-A did not follow a decreasing trend in contrast to VEGF-C, which decreased both in serum and vitreous...
August 16, 2018: Turkish Journal of Medical Sciences
Michael A Lavor, Georgina M Michael, Yeabsera G Tamire, Nicole D Dorofee
Introduction: Meshed split-thickness skin grafting represents a rapid and effective technique for surgical wound closure. Factors such as ongoing inflammation, microbial colonization, and a poorly vascularized wound bed increase the rate of skin autograft failure up to 33%. Because of the inherent angiogenic, anti-inflammatory, antimicrobial, and antifibrotic properties of human placental membranes, the complementary use of human placental membranes may promote graft survival and improve success rate for complete ulcer resolution...
2018: Eplasty
Alexa A Freedman, Carol J Hogue, Carmen J Marsit, Augustine Rajakumar, Alicia K Smith, Robert L Goldenberg, Donald J Dudley, George R Saade, Robert M Silver, Karen J Gibbins, Barbara J Stoll, Radek Bukowski, Carolyn Drews-Botsch
The placenta plays a critical role in regulating fetal growth. Recent studies suggest that there may be sex-specific differences in placental development. The purpose of our study was to evaluate the associations between birthweight and placental morphology in models adjusted for covariates and to assess sex-specific differences in these associations. We analyzed data from the Stillbirth Collaborative Research Network's population-based case-control study conducted between 2006 and 2008, which recruited cases of stillbirth and population-based controls in 5 states...
July 16, 2018: Pediatric and Developmental Pathology
Yun Cao, Haixiang Sun, Hui Zhu, Xianghong Zhu, Xiaoqiu Tang, Guijun Yan, Jingmei Wang, Donghui Bai, Juan Wang, Liu Wang, Qi Zhou, Huiyan Wang, Chengyan Dai, Lijun Ding, Biyun Xu, Yan Zhou, Jie Hao, Jianwu Dai, Yali Hu
BACKGROUND: Intrauterine adhesions (IUA) are the most common cause of uterine infertility and are caused by endometrium fibrotic regeneration following severe damage to the endometrium. Although current stem cell treatment options using different types of autologous stem cells have exhibited some beneficial outcomes in IUA patients, the reported drawbacks include variable therapeutic efficacies, invasiveness and treatment unavailability. Therefore, the development of new therapeutic stem cell treatments is critical to improving clinical outcomes...
July 11, 2018: Stem Cell Research & Therapy
Amarnath Bhide, Arianna Laoreti, Andrea Kaelin Agten, Aris Papageorghiou, Asma Khalil, James Uprichard, Basky Thilaganathan, Edwin Chandraharan
INTRODUCTION: Ultrasound signs of abnormal placental invasion are subjective in nature. We tested the hypothesis that placental thickness in the lower uterine segment is increased when there is abnormally invasive placenta (AIP) in women with a low-lying placenta. MATERIAL AND METHODS: Retrospective analysis of data of placental thickness in women with ultrasound evidence of major placenta previa or a low-lying anterior placenta was done. The diagnosis of AIP was confirmed both intraoperatively and on histopathology for those managed by partial myometrial excision with uterine conservation or by hysterectomy...
July 6, 2018: Acta Obstetricia et Gynecologica Scandinavica
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"