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Placental thickness

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https://www.readbyqxmd.com/read/28718186/intrauterine-growth-restriction-iugr-induces-signs-of-subclinical-atherosclerosis-in-6-year-old-infants-despite-absence-of-excessive-growth
#1
Anja Tzschoppe, Rüdiger von Kries, Ellen Struwe, Wolfgang Rascher, Helmuth-Guenther Dörr, Jörg Jüngert, Manfred Rauh, Matthias Beckmann, Ralf Schild, Tamme W Goecke, Jörg Dötsch
Background Postnatal catch-up growth and rapid weight gain after intrauterine growth restriction (IUGR) seem to increase the risk for later disease. This study aimed to compare features of the metabolic syndrome early in life between IUGR and appropriate for gestational age (AGA) infants. Patients Data for 9 infants with IUGR defined by a birth weight<10(th) percentile and ultrasound-proven placental insufficiency and 11 AGA children were available. Method Postnatal growth, auxological, cardiovascular, and metabolic parameters up to a chronological age of 6 years were assessed: Fasting serum concentrations of LDL-cholesterol, insulin, leptin, IGF-I, DHEAS, skinfold thicknesses, blood pressure, and mean carotid intima-media thickness (cIMT)...
July 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28709848/hydrogen-sulfide-alleviates-placental-injury-induced-by-maternal-cigarette-smoke-exposure-during-pregnancy-in-rats
#2
Fusheng Zhao, Fang Lei, Senfeng Zhang, Xiang Yan, Wen Wang, Yu Zheng
Maternal cigarette smoke exposure (CSE) during pregnancy is a well recognized causative factor for placental injury. Hydrogen sulfide (H2S), a gaseous signal molecule, has been shown to exert a protective effect against tissue injury in many organs. This study aimed to investigate whether H2S could alleviate CSE-induced placental injury in rats. Pregnant SD rats were randomly divided into 4 groups: NaCl, CSE, CSE + NaHS (a donor of H2S) and NaHS. On gestational day 21, placental weight was measured. Placental H2S content was assessed by methylene blue method...
July 11, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28690864/surgical-site-infections-after-cesarean-delivery-epidemiology-prevention-and-treatment
#3
REVIEW
Tetsuya Kawakita, Helain J Landy
Cesarean delivery (CD) is one of the most common procedures performed in the United States, accounting for 32% of all deliveries. Postpartum surgical site infection (SSI), wound infection and endometritis is a major cause of prolonged hospital stay and poses a burden to the health care system. SSIs complicate a significant number of patients who undergo CD - 2-7% will experience sound infections and 2-16% will develop endometritis. Many risk factors for SSI have been described. These include maternal factors (such as tobacco use; limited prenatal care; obesity; corticosteroid use; nulliparity; twin gestations; and previous CD), intrapartum and operative factors (such as chorioamnionitis; premature rupture of membranes; prolonged rupture of membranes; prolonged labor, particularly prolonged second stage; large incision length; subcutaneous tissue thickness > 3 cm; subcutaneous hematoma; lack of antibiotic prophylaxis; emergency delivery; and excessive blood loss), and obstetrical care on the teaching service of an academic institution...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28658297/abnormal-dendritic-maturation-of-developing-cortical-neurons-exposed-to-corticotropin-releasing-hormone-crh-insights-into-effects-of-prenatal-adversity
#4
Megan M Curran, Curt A Sandman, Elysia Poggi Davis, Laura M Glynn, Tallie Z Baram
Corticotropin releasing hormone (CRH) produced by the hypothalamus initiates the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body's stress response. CRH levels typically are undetectable in human plasma, but during pregnancy the primate placenta synthesizes and releases large amounts of CRH into both maternal and fetal circulations. Notably, placental CRH synthesis increases in response to maternal stress signals. There is evidence that human fetal exposure to high concentrations of placental CRH is associated with behavioral consequences during infancy and into childhood, however the direct effects on of the peptide on the human brain are unknown...
2017: PloS One
https://www.readbyqxmd.com/read/28653041/plasmodium-falciparum-genotypes-in-matched-peripheral-placental-and-umbilical-cord-blood-in-an-area-characterised-by-unstable-malaria-transmission-in-eastern-sudan
#5
Omar E Fadlelseed, Maha E Osman, Nahla M Shamseldin, Amar B Elhussein, Ishag Adam
BACKGROUND: There are few published studies on Plasmodium falciparum genotypes in peripheral, placental and umbilical cord blood in areas characterised by unstable malaria transmission. METHOD: A cross-sectional study was conducted to investigate P. falciparum genotypes in matched peripheral, placental and umbilical cord blood in eastern Sudan. Thick blood smears and P. falciparum merozoite surface protein 1 (MSP1) and 2 (MSP2) genes as polymorphic markers in polymerase chain reactions were investigated in 3 kinds of samples of 153 pregnant women at delivery...
June 2017: Heliyon
https://www.readbyqxmd.com/read/28631507/placental-thickness-to-estimated-foetal-weight-ratios-and-small-for-gestational-age-infants-at-delivery
#6
Ki Hoon Ahn, Joo Hak Lee, Geum Joon Cho, Soon-Cheol Hong, Min-Jeong Oh, Hai-Joong Kim
This study aimed to determine the correlation between the placental thickness-to-estimated foetal weight ratio on midterm ultrasonography and small-for-gestational-age (SGA) infants. In this retrospective study, the placental thickness at the umbilical cord insertion site was measured and adjusted for foetal body weight at 18-24 weeks gestation. Investigators compared the data of women who delivered SGA infants (birth weight <10th percentile) with those of women who delivered non-SGA infants. Among the 1281 women in this study, those who delivered SGA infants were younger and less likely to be obese...
June 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28623971/remodelling-of-the-bovine-placenta-comprehensive-morphological-and-histomorphological-characterization-at-the-late-embryonic-and-early-accelerated-fetal-growth-stages
#7
Consuelo Amor S Estrella, Karen L Kind, Anna Derks, Ruidong Xiang, Nicole Faulkner, Melina Mohrdick, Carolyn Fitzsimmons, Zbigniew Kruk, Frank Grutzner, Claire T Roberts, Stefan Hiendleder
INTRODUCTION: Placental function impacts growth and development with lifelong consequences for performance and health. We provide novel insights into placental development in bovine, an important agricultural species and biomedical model. METHODS: Concepti with defined genetics and sex were recovered from nulliparous dams managed under standardized conditions to study placental gross morphological and histomorphological parameters at the late embryo (Day48) and early accelerated fetal growth (Day153) stages...
July 2017: Placenta
https://www.readbyqxmd.com/read/28599899/placenta-accreta-spectrum-pathophysiology-and-evidence-based-anatomy-for-prenatal-ultrasound-imaging
#8
REVIEW
Eric Jauniaux, Sally Collins, Graham J Burton
Placenta accreta spectrum is a complex obstetric complication associated with high maternal morbidity. It is a relatively new disorder of placentation, and is the consequence of damage to the endometrium-myometrial interface of the uterine wall. When first described 80 years ago, it mainly occurred after manual removal of the placenta, uterine curettage, or endometritis. Superficial damage leads primarily to an abnormally adherent placenta, and is diagnosed as the complete or partial absence of the decidua on histology...
June 24, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28564655/aqueous-humor-levels-of-soluble-vascular-endothelial-growth-factor-receptor-and-inflammatory-factors-in-diabetic-macular-edema
#9
Hidetaka Noma, Tatsuya Mimura, Kanako Yasuda, Ryosuke Motohashi, Osamu Kotake, Masahiko Shimura
Aqueous levels of soluble vascular endothelial growth factor receptor (sVEGFR) and inflammatory factors were measured in 35 patients (37 eyes) with diabetic macular edema (DME) receiving anti-vascular endothelial growth factor (VEGF) therapy. Aqueous levels of growth factors (VEGF, placental growth factor [PlGF], and platelet-derived growth factor AA [PDGF-AA]), sVEGFR-1 and -2, soluble intercellular adhesion molecule 1, monocyte chemotactic protein (MCP)-1, interleukin (IL)-6, -8, -12, and -13, and interferon-inducible 10-kDa protein (IP-10) were significantly higher in the DME group than in the nondiabetic control group...
June 1, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28557152/quantified-discordant-placental-echogenicity-in-twin-anemia-polycythemia-sequence-taps-and-middle-cerebral-artery-peak-systolic-velocities
#10
Christian Bamberg, Anke Diemert, Peter Glosemeyer, Kurt Hecher
OBJECTIVE: To quantify sonographic placental echogenicity in twin anemia-polycythemia sequence (TAPS) and to correlate it with middle cerebral artery peak systolic velocities (MCA-PSV). METHODS: We performed a retrospective search for consecutive TAPS cases between 16 and 36 weeks of gestation (MCA-PSV >1.5 MoM and <1.0 MoM in the anemic donor and polycythemic recipient, respectively) in our database of monochorionic twin gestations from January 2007 until December 2016...
May 27, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28549829/impact-of-chlorpyrifos-on-human-villous-trophoblasts-and-chorionic-villi
#11
M E Ridano, A C Racca, J B Flores-Martin, R Fretes, C L Bandeira, L Reyna, E Bevilacqua, S Genti-Raimondi, G M Panzetta-Dutari
Placental barrier regulates maternal-fetal interchange protecting the baby from damage caused by substances found in the uterine environment or circulating in the vascular system. Organophosphate (OP) pesticides are a paramount group of environmental pollutants used in intensive agriculture for protection against diseases and pests. While many studies have reported an increased risk of pregnancy alterations in pregnant women exposed to OPs, few have analyzed the effects caused by these pesticides in the placenta...
May 23, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28540100/relationship-between-sonographic-placental-thickness-and-gestational-age-in-normal-singleton-fetuses-in-enugu-southeast-nigeria
#12
K K Agwuna, C U Eze, P O Ukoha, U A Umeh
BACKGROUND: The accuracy of common ultrasound parameters for the estimation of gestational age (GA) decreases as pregnancy advances in age. Hence, there is need to explore other parameters that may complement the established fetal biometric parameters in predicting GA in late pregnancy. AIM: The aim of this study is to determine the relationship between the sonographic placental thickness (PT) and GA in the second and third trimesters. SUBJECTS AND METHODS: A cross-sectional study of 627 normal pregnant women with GA between 14 and 40 weeks was conducted at the University of Nigeria Teaching Hospital Ituku-Ozalla, Enugu from May 2013 to February 2014 by sonography...
November 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28532830/transrectal-ultrasonography-for-measuring-of-combined-utero-placental-thickness-in-pregnant-mangalarga-marchador-mares
#13
REVIEW
Isabela S Campos, Guilherme N de Souza, Aline E Pinna, Ana M R Ferreira
This study aimed to measure the physiological changes in the combined utero-placental thickness (CUPT) during the course of normal pregnancy in Mangalarga Marchador mares. Transrectal B-mode ultrasonography was used to measure CUPT in 42 pregnant mares with a mean age, 8.7 (±3.5 years). CUPT was measured every month from 150 days of gestation until delivery. CUPT was expressed as an average of three measurements of the distance (mm) between the middle part of the uterine artery and the allantoic fluid. A General Linear Model was used to evaluate the major effects of the chronological age and stage of gestation on CUPT in mares...
July 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28523122/sex-differences-in-rat-placental-development-from-pre-implantation-to-late-gestation
#14
J I Kalisch-Smith, D G Simmons, M Pantaleon, K M Moritz
BACKGROUND: A male fetus is suggested to be more susceptible to in utero and birth complications. This may be due in part to altered morphology or function of the XY placenta. We hypothesised that sexual dimorphism begins at the blastocyst stage with sex differences in the progenitor trophectoderm (TE) and its derived trophoblast lineages, as these cells populate the majority of cell types within the placenta. We investigated sex-specific differences in cell allocation in the pre-implantation embryo and further characterised growth and gene expression of the placental compartments from the early stages of the definitive placenta through to late gestation...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28508539/the-effect-of-maternal-obesity-on-fatty-acid-transporter-expression-and-lipid-metabolism-in-the-full-term-placenta-of-lean-breed-swine
#15
L Tian, S S Dong, J Hu, J J Yao, P S Yan
This study was conducted to evaluate the influence of back-fat thickness (BF), at mating of sows, on the maternal and newborn circulating lipids, expression of placental fatty acids (FA) transporters and lipid accumulation in placenta. Full-term placentas were obtained by vaginal delivery from BFI (9-14 mm; n = 37), BFII (15-19 mm; n = 43) and BFIII (20-27 mm; n = 38) sows according to BF at mating, and frozen placental sections were analysed for fat accumulation. Blood samples were collected from the sows of day 105 pregnancy and from cord blood at delivery...
May 15, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28487023/redefining-3dimensional-placental-membrane-microarchitecture-using-multiphoton-microscopy-and-optical-clearing
#16
Lauren Richardson, Gracie Vargas, Tyra Brown, Lorenzo Ochoa, Jayshil Trivedi, Marian Kacerovský, Martha Lappas, Ramkumar Menon
INTRODUCTION: Remodeling of human placental membranes (amniochorionic or fetalmembrane) throughout gestation, a necessity to accommodate increasing uterine volume, involves continuous alterations (replacement of cells and remodeling of extracellular matrix). Methodologic limitations have obscured microscopic determination of cellular and layer-level alterations. This study used a combination of advanced imaging by multiphoton autofluorescence microscopy (MPAM) and second harmonic generation (SHG) microscopy along with tissue optical clearing to characterize the 3Dimensional multilayer organization of placental membranes...
May 2017: Placenta
https://www.readbyqxmd.com/read/28458694/submicroscopic-and-asymptomatic-congenital-infection-by-plasmodium-vivax-or-p-falciparum-in-colombia-37-cases-with-placental-histopathology-and-cytokine-profile-in-maternal-and-placental-blood
#17
Olga María Agudelo-García, Eliana María Arango-Flórez, Jaime Carmona-Fonseca
Problem. Congenital plasmodial infection (CPI) is a rare event, which has been little studied in Colombia. Objective. To measure the frequency of CPI and to describe the immune and histological characteristics in maternal blood and placentas when CPI occurs. Methodology. A cross-sectional study was carried out in northwest Colombia. A sample size of 39 unit analysis (a unit of analysis corresponds to the cord, placenta, and peripheral blood of a pregnant woman) was calculated using epidemiological and statistical parameters...
2017: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28403020/understanding-the-impact-of-preservation-methods-on-the-integrity-and-functionality-of-placental-allografts
#18
Amy Johnson, Alexandra Gyurdieva, Sandeep Dhall, Alla Danilkovitch, Yi Duan-Arnold
INTRODUCTION: Human placental membranes (hPMs) have a long history in treating burns and wounds. The composition of hPMs includes structural matrix, growth factors, and neonatal cells, all of which contribute to their regenerative potential. However, most hPM products are devitalized after dehydration and irradiation. We compared the functionality of single-layer viable cryopreserved human amniotic membrane (vCHAM) with multilayer devitalized dehydrated human amnion/chorion membrane (dHACM) in wound-relevant models to determine the effect of different processing methods on hPMs...
April 12, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28377901/unusual-presentation-of-invasive-mole-a-case-report
#19
Soheila Aminimoghaddam, Andisheh Maghsoudnia
BACKGROUND: Invasive mole is responsible for most cases of localized gestational trophoblastic neoplasia. Gestational trophoblastic disease describes a number of gynecologic tumors that originate in trophoblastic layer including hydatidiform mole (complete or partial), invasive mole, choriocarcinoma, placental site trophoblastic tumor and epitheloid trophoblastic tumor. Invasive mole may arise from any pregnancy event although in most cases is diagnosed after molar pregnancy. Overall cure rate in low risk patients is nearly 100% and in high-risk patient 90%...
January 2017: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/28365905/aflibercept-a-review-in-macular-oedema-secondary-to-branch-retinal-vein-occlusion
#20
Sheridan M Hoy
Aflibercept (Eylea(®)) is a fully human, recombinant fusion protein available in various countries worldwide, including those of the EU, as well as the USA, for intravitreal use in the treatment of macular oedema secondary to branch retinal vein occlusion (BRVO) in adults. Aflibercept acts as a soluble decoy receptor, binding with high affinity to vascular endothelial growth factor (VEGF)-A and placental growth factor (PIGF), preventing these angiogenic factors from binding to and activating their cognate receptors...
April 1, 2017: Drugs & Aging
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