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Remote isch,

Tamás Baranyai, Csilla Terézia Nagy, Gábor Koncsos, Zsófia Onódi, Melinda Károlyi-Szabó, András Makkos, Zoltán V Varga, Péter Ferdinandy, Zoltán Giricz
BACKGROUND: Remote ischemic perconditioning (RIPerC) has a promising therapeutic insight to improve the prognosis of acute myocardial infarction. Chronic comorbidities such as diabetes are known to interfere with conditioning interventions by modulating cardioprotective signaling pathways, such as e.g., mTOR pathway and autophagy. However, the effect of acute hyperglycemia on RIPerC has not been studied so far. Therefore, here we investigated the effect of acute hyperglycemia on cardioprotection by RIPerC...
2015: Cardiovascular Diabetology
Ammar H Hawasli, Wilson Z Ray, Neill M Wright
BACKGROUND AND IMPORTANCE: Idiopathic spinal cord herniation (ISCH) is an uncommon condition located predominantly in the thoracic spine and often associated with a remote history of a major traumatic injury. ISCH has an incompletely described presentation and unknown etiology. There is no consensus on the treatment algorithm and surgical technique, and there are few data on clinical outcomes. CLINICAL PRESENTATION: In this case series and technical report, we describe the atypical myelopathy presentation, remote history of traumatic injury, radiographic progression, treatment, and outcomes of 5 patients treated at Washington University for symptomatic ISCH...
September 2014: Neurosurgery
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