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diarrhea and probiotics

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https://www.readbyqxmd.com/read/29446765/gut-microbiota-based-therapies-for-irritable-bowel-syndrome
#1
Emily K Stern, Darren M Brenner
Irritable bowel syndrome (IBS) is a common, heterogeneous disorder characterized by abdominal pain associated with changes in bowel habits. The pathogenesis of IBS is multifactorial and may relate to alterations in the gut microbiota, changes in visceral sensation and motility, and genetic and environmental factors. Administration of systemic antibiotics may increase the risk of IBS by altering gastrointestinal homeostasis. Therapeutic interventions for IBS with diarrhea that are thought to target alterations in the gut microbiota include the nonsystemic antibiotic rifaximin, the medical food serum-derived bovine immunoglobulin, prebiotics, probiotics, and dietary modification...
February 15, 2018: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/29445178/the-effect-of-clostridium-butyricum-on-symptoms-and-fecal-microbiota-in-diarrhea-dominant-irritable-bowel-syndrome-a-randomized-double-blind-placebo-controlled-trial
#2
Yi-Yuan Sun, Ming Li, Yue-Yue Li, Li-Xiang Li, Wen-Zhe Zhai, Peng Wang, Xiao-Xiao Yang, Xiang Gu, Li-Jin Song, Zhen Li, Xiu-Li Zuo, Yan-Qing Li
Irritable bowel syndrome (IBS) is a common disorder in gastrointestinal system and impairs the quality of life of the patients. Clostridium butyricum (CB) is a probiotics that has been used in several gastrointestinal diseases. The efficacy of CB in treating IBS is still unknown. This prospective, multi-centre, randomized, double-blind, placebo-controlled trial aimed to assess the efficacy and safety of CB in treating diarrhea-predominant IBS (IBS-D) and analyze the fecal microbiota after treatment. Two hundred patients with IBS-D were recruited and were given CB or placebo for 4 weeks...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29426709/diagnosis-and-treatment-of-undifferentiated-and-infectious-acute-diarrhea-in-the-adult-horse
#3
REVIEW
Sarah D Shaw, Henry Stämpfli
Acute, infectious, diarrhea in adult horses is a major cause of morbidity and is associated with numerous complications. Common causes include salmonellosis, clostridiosis, Coronavirus, and infection with Neorickettsia risticii (Potomac horse fever). Treatment is empirical and supportive until results of specific diagnostic tests are available. Supportive care is aimed at restoring hydration, correcting electrolyte imbalances, and limiting the systemic inflammatory response. The mainstays of therapy are intravenous fluid therapy, electrolyte supplementation where necessary, nonsteroidal anti-inflammatory agents, and nutritional support...
February 6, 2018: Veterinary Clinics of North America. Equine Practice
https://www.readbyqxmd.com/read/29415828/sporulated-bacillus-as-alternative-treatment-for-diarrhea-of-hospitalized-adult-patients-under-enteral-nutrition-a-pilot-randomized-controlled-study
#4
Gustavo Gomes de Castro Soares, Carlos Hespanha Marinho, Regiane Pitol, Camila Andretta, Edinaldo Oliveira, Cristina Martins, Miguel Carlos Riella
BACKGROUND & AIMS: Among hospitalized patients receiving enteral nutrition (EN), malnutrition and antibiotic use are some of the most common causes of diarrhea. Prebiotics and probiotics agents have been used for treatment of diarrhea in such patients. The aim of this study was to assess the efficacy of a sporulated Bacillus strain (Bacillus cereus A 05), compared to a control group using a prebiotic (soluble fiber), in reducing diarrhea in patients receiving EN and antibiotic therapy...
December 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29413218/evidence-based-practice-in-the-treatment-for-antibiotic-associated-diarrhea-in-the-intensive-care-unit
#5
REVIEW
Robin Squellati
Unit nurses provide care to patients with serious health conditions. Often antibiotics are recommended to fight infections. Sometimes patients are on proton pump inhibitors (PPI). Antibiotics and PPIs may lead to diarrhea, causing the patient more discomfort, and possibly leading to a more serious infection. One serious infection is caused by Clostridium difficile, which causes death in some cases. About 75% of patients on antibiotics may not need antibiotics. Several studies showed less diarrhea in patients on probiotics...
March 2018: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/29402478/probiotic-use-in-equine-gastrointestinal-disease
#6
REVIEW
Angelika Schoster
Probiotics are commonly used in human and veterinary medicine due to their postulated positive effects on overall and specifically gastrointestinal health. Although some beneficial effects have been shown in several human diseases, a general beneficial effect of probiotics is currently not supported. In horses, well-designed studies to date are few, results are conflicting, and the effects of probiotics are questionable. Adverse effects are rare; however, intestinal adverse effects (diarrhea) have been reported in foals...
February 2, 2018: Veterinary Clinics of North America. Equine Practice
https://www.readbyqxmd.com/read/29391004/interventions-to-reduce-post-acute-consequences-of-diarrheal-disease-in-children-a-systematic-review
#7
Patricia B Pavlinac, Rebecca L Brander, Hannah E Atlas, Grace C John-Stewart, Donna M Denno, Judd L Walson
BACKGROUND: Although acute diarrhea often leads to acute dehydration and electrolyte imbalance, children with diarrhea also suffer long term morbidity, including recurrent or prolonged diarrhea, loss of weight, and linear growth faltering. They are also at increased risk of post-acute mortality. The objective of this systematic review was to identify interventions that address these longer term consequences of diarrhea. METHODS: We searched Medline for randomized controlled trials (RCTs) of interventions conducted in low- and middle-income countries, published between 1980 and 2016 that included children under 15 years of age with diarrhea and follow-up of at least 7 days...
February 1, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29355277/probiotic-prebiotic-correction-for-adverse-effects-of-iron-fortification-on-intestinal-resistance-to-salmonella-infection-in-weaning-mice
#8
Feifei Lin, Haohao Wu, Mingyong Zeng, Guangli Yu, Shiyuan Dong, Huicheng Yang
Iron fortification has been associated with a modest increase in diarrhea risk among children. Herein, we investigate the correction for this unwanted side effect with probiotic/prebiotic supplementation in weaning mice. Iron fortification with 250 ppm and 500 ppm ferrous sulfate for 30 days significantly increased the species richness of the mouse gut microbiota compared to controls. The 500 ppm-FeSO4 diet caused a significantly decreased abundance of potentially beneficial Lactobacillus. During infection with the foodborne pathogen Salmonella enterica serovar Typhimurium (S...
January 22, 2018: Food & Function
https://www.readbyqxmd.com/read/29290433/associations-between-management-practices-and-within-pen-prevalence-of-calf-diarrhea-and-respiratory-disease-on-dairy-farms-using-automated-milk-feeders
#9
Catalina Medrano-Galarza, Stephen J LeBlanc, Andria Jones-Bitton, Trevor J DeVries, Jeffrey Rushen, Anne Marie de Passillé, Marcia I Endres, Derek B Haley
Data on management practices used with automated milk feeders (AMF) are needed to identify factors associated with calf health in these systems. The objectives of this observational, longitudinal, cross-sectional study were to estimate the prevalence of calf diarrhea (CD) and bovine respiratory disease (BRD), and to identify factors associated with prevalence of these diseases at the pen level on dairy farms feeding milk to group-housed calves with AMF. Seventeen dairy farms with AMF in Ontario, Canada, were visited 4 times, seasonally, over 1 yr...
December 28, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29280118/-effects-of-perioperative-intestinal-microecological-treatment-on-postoperative-complications-and-gastrointestinal-function-in-patients-with-refractory-functional-constipation
#10
Qiyi Chen, Xiaobo Feng, Ling Ni, Hongliang Tian, Guangke Li, Jun Jiang, Ning Li, Jieshou Li
OBJECTIVE: To investigate the effects of perioperative intestinal microecological treatment on postoperative complications and gastrointestinal function in patients with refractory functional constipation by nonrandomized controlled trial. METHODS: A total of 198 patients with refractory functional constipation who underwent Jinling procedure in our department from 2014 to 2015 were prospectively enrolled, and were divided into conventional treatment group (n=100, routine intestinal preparation was used before operation; probiotics and prebiotics were applied if diarrhea or abdominal distention occurred after operation) and microecological treatment group (n=98, routine perioperative management was applied; probiotics, prebiotics and enteral nutrition were administered since 2 weeks before operation; probiotics and prebiotics were given again when exhaust and defecation recovered after operation)...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29259371/probiotics-for-gastrointestinal-disorders-proposed-recommendations-for-children-of-the-asia-pacific-region
#11
REVIEW
Donald Cameron, Quak Seng Hock, Musal Kadim, Neelam Mohan, Eell Ryoo, Bhupinder Sandhu, Yuichiro Yamashiro, Chen Jie, Hans Hoekstra, Alfredo Guarino
Recommendations for probiotics are available in several regions. This paper proposes recommendations for probiotics in pediatric gastrointestinal diseases in the Asia-Pacific region. Epidemiology and clinical patterns of intestinal diseases in Asia-Pacific countries were discussed. Evidence-based recommendations and randomized controlled trials in the region were revised. Cultural aspects, health management issues and economic factors were also considered. Final recommendations were approved by applying the Likert scale and rated using the GRADE system...
December 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29234140/altered-gut-microbiota-profiles-in-sows-and-neonatal-piglets-associated-with-porcine-epidemic-diarrhea-virus-infection
#12
Deping Song, Qi Peng, Yanjun Chen, Xinrong Zhou, Fanfan Zhang, Anqi Li, Dongyan Huang, Qiong Wu, Yu Ye, Houjun He, Leyi Wang, Yuxin Tang
Porcine epidemic diarrhea virus (PEDV) is a devastating cause of diarrhea in pigs worldwide. Most of studies have focused on molecular and pathogenic characterization of PEDV, whereas there were limited studies in understanding the role of gut microbiota (GM) in viral-associated diarrhea. Here, using the Illumina MiSeq platform, we examined and compared the impact of PEDV infection on the GM of sows and their piglets less than 10 days old. Our results showed that PEDV caused alternations in the structure and abundance of GM from levels of phylum to genus, and even species...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29202875/postoperative-changes-of-the-microbiome-are-surgical-complications-related-to-the-gut-flora-a-systematic-review
#13
Ann-Kathrin Lederer, Przemyslaw Pisarski, Lampros Kousoulas, Stefan Fichtner-Feigl, Carolin Hess, Roman Huber
BACKGROUND: The purpose of this review was to identify the relationship between the gut microbiome and the development of postoperative complications like anastomotic leakage or a wound infection. Recent reviews focusing on underlying molecular biology suggested that postoperative complications might be influenced by the patients' gut flora. Therefore, a review focusing on the available clinical data is needed. METHODS: In January 2017 a systematic search was carried out in Medline and WebOfScience to identify all clinical studies, which investigated postoperative complications after gastrointestinal surgery in relation to the microbiome of the gut...
December 4, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29201766/are-synbiotics-added-to-the-standard-therapy-to-eradicate-helicobacter-pylori-in-children-beneficial-a-randomized-controlled-study
#14
Banu N Şirvan, Merve K Usta, Nurav U Kizilkan, Nafive Urganci
Aim: We aimed to evaluate the role of the addition of Bifidobacterium /actis-containing synbiotic to the triple therapy in the case of He/icobacter py/ori eradication, the dyspeptic symptoms, and reducing the side effects of antibiotics. Materials and methods: A total of 104 children aged between 5 and 17 years, who were histopathologically diagnosed with H. py/ori were enrolled in this study, of whom 100 were included in the analysis. Patients were randomly classified into two groups...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29170638/volatile-oil-from-amomi-fructus-attenuates-5-fluorouracil-induced-intestinal-mucositis
#15
Ting Zhang, Shan H Lu, Qian Bi, Li Liang, Yan F Wang, Xing X Yang, Wen Gu, Jie Yu
Amomi Fructus has been used to treat digestive diseases in the context of traditional Chinese medicine, so we evaluated the effects of a volatile oil from Amomum villosum (VOA) on intestinal mucositis induced by 5-fluorouracil (5-FU). We measured the effect of VOA and its main active constituent, bornyl acetate (BA), on body weight, food intake, diarrhea, inflammatory cytokines, the mucosal barrier, and gut microbiota. VOA and BA significantly increased the rats' body weight, relieved diarrhea, and reversed histopathological changes in the gut and inflammation...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29161712/clostridium-difficile-infection-in-the-nephrology-ward
#16
Sylwia Dudzicz, Marcin Adamczak, Andrzej Więcek
Clostridium difficile is currently the most frequently identified pathogen causing antibiotic-associated diarrhea and the main cause of nosocomial diarrhea. In recent years, increases incidence of infection, severe infection, recurrent infection and mortality from Clostridium difficile infection (CDI) have been observed. This may be a consequence of excessive antibiotic use and spread of the hypervirulent epidemic BI/NAP1/027 strain of Clostridium difficile. The main risk factors for CDI are: antibiotic therapy, previous hospitalizations and number of comorbid conditions...
November 21, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29151426/-effects-of-antibiotics-on-intestinal-microflora-and-intestinal-mucosal-barrier-function-and-its-mechanisms
#17
Yue Han, Yuxin Leng, Gaiqi Yao
Antibiotics are the cornerstone to cure infectious diseases, however, it also destroys the intestinal inherent microflora, and may cause serious gastrointestinal dysfunction, such as abdominal distension, diarrhea, mucosal barrier damage etc. In severe conditions, it may induce intestinal sepsis. With the development of the human microbiology group program and the popularity of microbial sequencing technology, people can comprehend the effects of antibiotics on intestinal flora deeply, meanwhile the traditional biomedical model (the basis of bacterial disease) is questioned...
November 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29135456/probiotics-and-their-use-in-inflammatory-bowel-disease
#18
Muhammad Amer, Muhammad Nadeem, Saeed Ur Rashid Nazir, Maira Fakhar, Fatima Abid, Qurat-Ul Ain, Elliyah Asif
Context • Crohn's disease and ulcerative colitis result in similar gastrointestinal (GI) symptoms, including pain, diarrhea, stools with mucus or blood, and ulceration or tissue damage within the alimentary canal. Gut microbiota play a crucial role in triggering, maintaining, and exacerbating inflammatory bowel disease (IBD). Probiotics might help to rebalance the gut flora in a positive way, shifting from pro- to anti-inflammatory. Objectives • The study intended to investigate the safety and use of probiotics and the biological effects of probiotic bacteria on IBD...
November 14, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29127772/interventions-for-treating-collagenous-colitis
#19
REVIEW
Tahir S Kafil, Tran M Nguyen, Petrease H Patton, John K MacDonald, Nilesh Chande, John Wd McDonald
BACKGROUND: Collagenous colitis is a cause of chronic diarrhea. This updated review was performed to identify therapies for collagenous colitis that have been assessed in randomized controlled trials (RCTs). OBJECTIVES: The primary objective was to assess the benefits and harms of treatments for collagenous colitis. SEARCH METHODS: We searched CENTRAL, the Cochrane IBD Group Specialized Register, MEDLINE and EMBASE from inception to 7 November 2016...
November 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29121702/preventive-effects-of-a-probiotic-mixture-in-an-ovalbumin-induced-food-allergy-model
#20
Hee-Soon Shin, Ji-Eun Eom, Dong-Uk Shin, Sung-Hum Yeon, Seong-Il Lim, So-Young Lee
Although there has been a steady increase in the prevalence of food allergies worldwide in recent decades, no effective therapeutic strategies have been developed. Modulation of the gut microbiota composition and/or function through probiotics has been highlighted as a promising target for protection against food allergies. In this study, we aimed to investigate the allergy-reducing effects of a probiotic mixture (P5: Lactococcus lactis KF140, Pediococcus pentosaceus KF159, Lactobacillus pentosus KF340, Lactobacillus paracasei 698, and Bacillus amyloliquefaciens 26N) in mice with ovalbumin (OVA)-induced food allergy...
November 9, 2017: Journal of Microbiology and Biotechnology
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