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https://www.readbyqxmd.com/read/29764777/comparison-of-social-interaction-between-cochlear-implanted-children-with-normal-intelligence-undergoing-auditory-verbal-therapy-and-normal-hearing-children-a-pilot-study
#1
Leila Monshizadeh, Roshanak Vameghi, Firoozeh Sajedi, Fariba Yadegari, Seyed Basir Hashemi, Petra Kirchem, Fatemeh Kasbi
OBJECTIVE: A cochlear implant is a device that helps hearing-impaired children by transmitting sound signals to the brain and helping them improve their speech, language, and social interaction. Although various studies have investigated the different aspects of speech perception and language acquisition in cochlear-implanted children, little is known about their social skills, particularly Persian-speaking cochlear-implanted children. Considering the growing number of cochlear implants being performed in Iran and the increasing importance of developing near-normal social skills as one of the ultimate goals of cochlear implantation, this study was performed to compare the social interaction between Iranian cochlear-implanted children who have undergone rehabilitation (auditory verbal therapy) after surgery and normal-hearing children...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29759558/the-influence-of-genetic-variation-on-late-toxicities-in-childhood-cancer-survivors-a-review
#2
REVIEW
E Clemens, A L F van der Kooi, L Broer, E van Dulmen-den Broeder, H Visscher, L Kremer, W Tissing, J Loonen, C M Ronckers, S M F Pluijm, S J C M M Neggers, O Zolk, T Langer, A Am Zehnhoff-Dinnesen, C L Wilson, M M Hudson, B Carleton, J S E Laven, A G Uitterlinden, M M van den Heuvel-Eibrink
INTRODUCTION: The variability in late toxicities among childhood cancer survivors (CCS) is only partially explained by treatment and baseline patient characteristics. Inter-individual variability in the association between treatment exposure and risk of late toxicity suggests that genetic variation possibly modifies this association. We reviewed the available literature on genetic susceptibility of late toxicity after childhood cancer treatment related to components of metabolic syndrome, bone mineral density, gonadal impairment and hearing impairment...
June 2018: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/29744729/supra-threshold-hearing-and-fluctuation-profiles-implications-for-sensorineural-and-hidden-hearing-loss
#3
REVIEW
Laurel H Carney
An important topic in contemporary auditory science is supra-threshold hearing. Difficulty hearing at conversational speech levels in background noise has long been recognized as a problem of sensorineural hearing loss, including that associated with aging (presbyacusis). Such difficulty in listeners with normal thresholds has received more attention recently, especially associated with descriptions of synaptopathy, the loss of auditory nerve (AN) fibers as a result of noise exposure or aging. Synaptopathy has been reported to cause a disproportionate loss of low- and medium-spontaneous rate (L/MSR) AN fibers...
May 9, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29728466/first-person-julia-abitbol
#4
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Julia Abitbol is the first author on 'Mice harbouring an oculodentodigital dysplasia-linked Cx43 G60S mutation have severe hearing loss', published in Journal of Cell Science. Julia is a PhD student in the lab of Dale Laird at the University of Western Ontario, Canada, investigating the mechanisms of connexin-induced hearing loss...
May 4, 2018: Journal of Cell Science
https://www.readbyqxmd.com/read/29716456/who-decides-what-is-acceptable-speech-on-campus-why-restricting-free-speech-is-not-the-answer
#5
Stephen J Ceci, Wendy M Williams
Recent protests on dozens of campuses have led to the cancellation of controversial talks, and violence has accompanied several of these protests. Psychological science provides an important lens through which to view, understand, and potentially reduce these conflicts. In this article, we frame opposing sides' arguments within a long-standing corpus of psychological research on selective perception, confirmation bias, myside bias, illusion of understanding, blind-spot bias, groupthink/in-group bias, motivated skepticism, and naive realism...
May 2018: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/29688963/how-to-optimally-fit-a-hearing-aid-for-bimodal-cochlear-implant-users-a-systematic-review
#6
Jantien L Vroegop, André Goedegebure, Marc P van der Schroeff
OBJECTIVES: Bimodal hearing has shown to improve speech recognition in quiet and in noise and to improve sound localization compared with unilateral cochlear implant (CI) use alone. Fitting the CI and hearing aid (HA) separately has been described well, but HA fitting procedures for bimodal CI users are not well researched or widely accepted. The aim of the present study was to systematically review the literature on the effect of different HA fitting strategies on auditory performance in bimodal CI users...
April 20, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29688112/protection-for-medication-induced-hearing-loss-the-state-of-the-science
#7
Tanisha L Hammill, Kathleen C Campbell
OBJECTIVE: This review will summarise the current state of development of pharmaceutical interventions (prevention or treatment) for medication-induced ototoxicity. DESIGN: Currently published literature was reviewed using PubMed and ClinicalTrials.gov to summarise the current state of the science. Details on the stage of development in the market pipeline are provided, along with evidence for clinical safety and efficacy reported. STUDY SAMPLE: This review includes reports from 44 articles and clinical trial reports regarding agents in clinical or preclinical trials, having reached approved Investigational New Drug status with the Federal Drug Administration...
April 24, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29683057/the-usefulness-of-science-knowledge-for-parents-of-hearing-impaired-children
#8
Sophie Shauli, Ayelet Baram-Tsabari
Hearing-impaired children's chances of integrating into hearing society largely depend on their parents, who need to learn vast amounts of science knowledge in the field of hearing. This study characterized the role played by science knowledge in the lives of nonscientists faced with science-related decisions by examining the interactions between general science knowledge, contextual science knowledge in the field of hearing, and parents' advocacy knowledge and attitudes. Based on six semi-structured interviews and 115 questionnaires completed by parents of hearing-impaired children, contextual science knowledge emerged as the only predictor for having slightly better advocacy attitudes and knowledge (5...
April 1, 2018: Public Understanding of Science
https://www.readbyqxmd.com/read/29672729/morphology-instruction-in-the-science-classroom-for-students-who-are-deaf-a-multiple-probe-across-content-analysis
#9
Jessica W Trussell, Jason Nordhaus, Alison Brusehaber, Brittany Amari
Deaf and hard-of-hearing (DHH) students have exhibited a morphological knowledge delay that begins in preschool and persists through college. Morphological knowledge is critical to vocabulary understanding and text comprehension in the science classroom. We investigated the effects of morphological instruction, commonly referred to as Word Detectives, on the morphological knowledge of college-age DHH students in a science course. We implemented a multiple probe across behaviors single-case experimental design study with nine student participants...
April 17, 2018: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/29661046/diagnostic-accuracy-of-tuning-fork-tests-for-hearing-loss-a-systematic-review
#10
Elizabeth A Kelly, Bin Li, Meredith E Adams
Objective (1) To determine the diagnostic accuracy of tuning fork tests (TFTs; Weber and Rinne) for assessment of hearing loss as compared with standard audiometry. (2) To identify the audiometric threshold at which TFTs transition from normal to abnormal, thus indicating the presence of hearing loss. Data Sources PubMed, Ovid Medline, EMBASE, Web of Science, Cochrane, and Scopus and manual bibliographic searches. Review Methods A systematic review of studies reporting TFT accuracy was performed according to a standardized protocol...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29619246/enhancing-the-incorporation-of-the-patient-s-voice-in-drug-development-and-evaluation
#11
Meghana Chalasani, Pujita Vaidya, Theresa Mullin
Plain English summary: People living with a condition are uniquely positioned to inform the understanding of the therapeutic context for drug development and evaluation. In 2012, the U.S. Food and Drug Administration (FDA) established the Patient-Focused Drug Development (PFDD) initiative to more systematically obtain the patient perspective on specific diseases and their currently available treatments. PFDD meetings are unique among FDA public meetings, with a format designed to engage patients and elicit their perspectives on two topic areas: (1) the most significant symptoms of their condition and the impact of the condition on daily life; and, (2) their current approaches to treatment...
2018: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29619109/polysomnography-applied-to-patients-with-tinnitus-a-review
#12
REVIEW
Liane Sousa Teixeira, Ronaldo Campos Granjeiro, Carlos Augusto Pires de Oliveira, Fayez Bahamad Júnior
Introduction  Tinnitus has been defined as an "auditory phantom perception," meaning that tinnitus results from an abnormal activity within the nervous system, in the absence of any internal or external acoustic stimulation. About 10 to 15% of the adult population is affected by tinnitus, and a relevant percentage of tinnitus sufferers experience symptoms severe enough to significantly affect quality of life, including sleep disturbances, work impairment, and, in some cases, psychiatric distress...
April 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29608150/trans-tympanic-drug-delivery-for-the-treatment-of-ototoxicity
#13
Kelly Sheehan, Sandeep Sheth, Debashree Mukherjea, Leonard P Rybak, Vickram Ramkumar
The systemic administration of protective agents to treat drug-induced ototoxicity is limited by the possibility that these protective agents could interfere with the chemotherapeutic efficacy of the primary drugs. This is especially true for the drug cisplatin, whose anticancer actions are attenuated by antioxidants which provide adequate protection against hearing loss. Other current or potential otoprotective agents could pose a similar problem, if administered systemically. The application of various biologicals or protective agents directly to the cochlea would allow for high levels of these agents locally with limited systemic side effects...
March 16, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29520008/social-contact-enhances-bodily-self-awareness
#14
Nesrine Hazem, Morgan Beaurenaut, Nathalie George, Laurence Conty
Human self-awareness is arguably the most important and revealing question of modern sciences. Converging theoretical perspectives link self-awareness and social abilities in human beings. In particular, mutual engagement during social interactions-or social contact-would boost self-awareness. Yet, empirical evidence for this effect is scarce. We recently showed that the perception of eye contact induces enhanced bodily self-awareness. Here, we aimed at extending these findings by testing the influence of social contact in auditory and tactile modalities, in order to demonstrate that social contact enhances bodily self-awareness irrespective of sensory modality...
March 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29515055/prevalence-of-diverse-complications-and-its-association-with-karyotypes-in-japanese-adult-women-with-turner-syndrome-a-questionnaire-survey-by-the-foundation-for-growth-science
#15
Kunihiko Hanew, Toshiaki Tanaka, Reiko Horikawa, Tomonobu Hasegawa, Susumu Yokoya
The reported prevalence of complications in Turner Syndrome (TS) was highly variable because of the rarity and the limited numbers analyzed. Again, possible presence of other complications that are not described as specific for TS, is also speculated. To resolve these issues, a questionnaire survey was conducted in hGH treated 492 patients with adult TS (17-42 years). The possible association with these complications and karyotypes were also analyzed. The complications and their prevalence were as follows: chronic thyroiditis (25...
March 7, 2018: Endocrine Journal
https://www.readbyqxmd.com/read/29514199/exploring-the-identities-of-hearing-parents-who-chose-cochlear-implantation-for-their-children-with-hearing-loss
#16
Kristina M Scharp, Brittan A Barker, Sidney N Rucker, Hannah D Jones
We aimed to determine the types of identities hearing parents construct when telling online stories about their children with hearing loss (HL) who use cochlear implants (CIs). To do so, we employed a qualitative design and sampled 20 different blogs United States origins and written by parents of children who use CIs. We then used thematic narrative analysis (Braun & Clarke, 2006; Riessman, C. K. (2008). Narrative methods for the human sciences. Thousand Oaks, CA: Sage Publications.) to uncover recurring themes from these parents' blogs...
April 1, 2018: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/29501366/concurrent-chemoradiotherapy-with-nedaplatin-versus-cisplatin-in-stage-ii-ivb-nasopharyngeal-carcinoma-an-open-label-non-inferiority-randomised-phase-3-trial
#17
Lin-Quan Tang, Dong-Ping Chen, Ling Guo, Hao-Yuan Mo, Ying Huang, Shan-Shan Guo, Bin Qi, Qing-Nan Tang, Pan Wang, Xiao-Yun Li, Ji-Bin Li, Qing Liu, Yuan-Hong Gao, Fang-Yun Xie, Li-Ting Liu, Yang Li, Sai-Lan Liu, Hao-Jun Xie, Yu-Jing Liang, Xue-Song Sun, Jin-Jie Yan, Yi-Shan Wu, Dong-Hua Luo, Pei-Yu Huang, Yan-Qun Xiang, Rui Sun, Ming-Yuan Chen, Xing Lv, Lin Wang, Wei-Xiong Xia, Chong Zhao, Ka-Jia Cao, Chao-Nan Qian, Xiang Guo, Ming-Huang Hong, Zhi-Qiang Nie, Qiu-Yan Chen, Hai-Qiang Mai
BACKGROUND: Cisplatin-based concurrent chemoradiotherapy is currently considered to be the standard treatment regimen for patients with advanced nasopharyngeal carcinoma, but has well known side-effects such as gastrointestinal reactions, nephrotoxicity, and ototoxicity. Nedaplatin was developed to decrease the toxic effects induced by cisplatin, and in this trial we assessed whether a nedaplatin-based concurrent chemoradiotherapy regimen was non-inferior to a cisplatin-based regimen in patients with locoregional, stage II-IVB nasopharyngeal carcinoma...
April 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29490694/systematic-review-of-ototoxic-pre-surgical-antiseptic-preparations-what-is-the-evidence
#18
REVIEW
Shubhi Singh, Brian Blakley
OBJECTIVE: There is uncertainty regarding the safety of surgical antiseptic preparations in the ear. A systematic review of the literature was conducted to assess the evidence regarding ototoxicity of surgical antiseptic preparations. METHODS: A literature search was conducted using the PRISMA methods. Key words included "ototoxicity" "hearing loss", "antiseptic", "surgical preparation", "tympanoplasty", "vestibular dysfunction", "chlorhexidine", "iodine", "povidone", "ethanol", and "hydrogen peroxide" using Medline, Embase, Cochrane Library, Scopus and Web of Science...
March 1, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29487106/an-interview-with-yk%C3%A3-helariutta
#19
Aidan Maartens
Yrjö (Ykä) Helariutta is a group leader at The Institute of Biotechnology in the University of Helsinki and at the Sainsbury Laboratory in the University of Cambridge. Recently appointed an editor at Development, his lab works on vascular development in plants and trees. We met Ykä in his Cambridge office to hear how a childhood passion for collecting led him to plant science, what Arabidopsis can tell us about trees and vice versa, and why he thinks there are many different ways of being successful in science...
February 27, 2018: Development
https://www.readbyqxmd.com/read/29451399/assistive-technology-for-communication-of-older-adults-a-systematic-review
#20
Thaiany Pedrozo Campos Antunes, Acary Souza Bulle de Oliveira, Robert Hudec, Tania Brusque Crocetta, Jennifer Yohanna Ferreira de Lima Antão, Renata Thais de Almeida Barbosa, Regiani Guarnieri, Thais Massetti, David M Garner, Luiz Carlos de Abreu
OBJECTIVE: Describe the use of assistive technology to enhance communication opportunities for older adults. METHODS: A systematic review was conducted in two databases, PubMed and Web of Science, by using two different searches in each. The search was limited to original articles, in English language, including people aged 60 years and older that used any type of assistive technology for communication. The articles found in the initial search were filtered by title, abstracts and the remaining articles were fully read...
February 16, 2018: Aging & Mental Health
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