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Auditory steady state response

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https://www.readbyqxmd.com/read/29147144/effects-of-spectral-smearing-of-stimuli-on-the-performance-of-auditory-steady-state-response-based-brain-computer-interface
#1
Jong Ho Hwang, Kyoung Won Nam, Dong Pyo Jang, In Young Kim
There have been few reports that investigated the effects of the degree and pattern of a spectral smearing of stimuli due to deteriorated hearing ability on the performance of auditory brain-computer interface (BCI) systems. In this study, we assumed that such spectral smearing of stimuli may affect the performance of an auditory steady-state response (ASSR)-based BCI system and performed subjective experiments using 10 normal-hearing subjects to verify this assumption. We constructed smearing-reflected stimuli using an 8-channel vocoder with moderate and severe hearing loss setups and, using these stimuli, performed subjective concentration tests with three symmetric and six asymmetric smearing patterns while recording electroencephalogram signals...
December 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29121385/a-controlled-comparison-of-auditory-steady-state-responses-and-pure-tone-audiometry-in-patients-with-hearing-loss
#2
Raman Wadhera, Sharad Hernot, Sat Paul Gulati, Vijay Kalra
We performed a prospective interventional study to evaluate correlations between hearing thresholds determined by pure-tone audiometry (PTA) and auditory steady-state response (ASSR) testing in two types of patients with hearing loss and a control group of persons with normal hearing. The study was conducted on 240 ears-80 ears with conductive hearing loss, 80 ears with sensorineural hearing loss, and 80 normal-hearing ears. We found that mean threshold differences between PTA results and ASSR testing at different frequencies did not exceed 15 dB in any group...
October 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29092566/linear-combination-of-auditory-steady-state-responses-evoked-by-co-modulated-tones
#3
François Guérit, Jeremy Marozeau, Bastian Epp
Up to medium intensities and in the 80-100-Hz region, the auditory steady-state response (ASSR) to a multi-tone carrier is commonly considered to be a linear sum of the dipoles from each tone specific ASSR generator. Here, this hypothesis was investigated when a unique modulation frequency is used for all carrier components. Listeners were presented with a co-modulated dual-frequency carrier (1 and 4 kHz), from which the modulator starting phase Φi of the 1-kHz component was systematically varied. The results support the hypothesis of a linear superposition of the dipoles originating from different frequency specific ASSR generators...
October 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29079460/optimized-auditory-transcranial-alternating-current-stimulation-improves-individual-auditory-temporal-resolution
#4
Alina Baltus, Sven Wagner, Carsten Hermann Wolters, Christoph Siegfried Herrmann
BACKGROUND: Temporal resolution of cortical, auditory processing mechanisms is suggested to be linked to peak frequency of neuronal gamma oscillations in auditory cortex areas (individual gamma frequency, IGF): Individuals with higher IGF tend to have better temporal resolution. HYPOTHESIS: Modulating ongoing gamma activity with transcranial alternating current stimulation (tACS) is expected to improve performance in gap detection (GD) tasks (shorter GD thresholds) if the frequency is higher and to decrease GD performance (longer GD thresholds) if the frequency is lower than IGF...
October 17, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29060380/high-density-ear-eeg
#5
Simon L Kappel, Preben Kidmose
Ear-EEG enables recording of EEG in real-life environments in an unprecedented discreet and minimal obtrusive way. As ear-EEG are recorded from electrodes placed in or around the ear, the spatial coverage of the potential field on the scalp is inherently limited. Despite the limited spatial coverage, the potential field in-the-ear can still be measured in multiple points and thereby provide spatial information. We present a method to perform and visualize high-density ear-EEG recordings, and illustrate the method through recordings of auditory and visually evoked steady-state responses, for a single subject...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29051085/40hz-auditory-steady-state-response-in-schizophrenia-sensitivity-to-stimulation-type-clicks-versus-flutter-amplitude-modulated-tones
#6
Inga Griskova-Bulanova, Kastytis Dapsys, Sigita Melynyte, Aleksandras Voicikas, Valentinas Maciulis, Sergejus Andruskevicius, Milena Korostenskaja
Auditory steady-state response (ASSR) at 40Hz has been proposed as a potential biomarker for schizophrenia. The ASSR studies in patients have used click stimulation or amplitude-modulated tones. However, the sensitivity of 40Hz ASSRs to different stimulation types in the same group of patients has not been previously evaluated. Two stimulation types for ASSRs were tested in this study: (1) 40Hz clicks and (2) flutter-amplitude modulated tones. The mean phase-locking index, evoked amplitude and event-related spectral perturbation values were compared between schizophrenia patients (n=26) and healthy controls (n=20)...
October 16, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29036430/delta-vs-gamma-auditory-steady-state-synchrony-in-schizophrenia
#7
Krishna C Puvvada, Ann Summerfelt, Xiaoming Du, Nithin Krishna, Peter Kochunov, Laura M Rowland, Jonathan Z Simon, L Elliot Hong
Background: Delta band (1-4 Hz) neuronal responses support the precision and stability of auditory processing, and a deficit in delta band synchrony may be relevant to auditory domain symptoms in schizophrenia patients. Methods: Delta band synchronization elicited by a 2.5 Hz auditory steady state response (ASSR) paradigm, along with those from theta (5 Hz), alpha (10 Hz), beta (20 Hz), gamma (40 Hz), and high gamma (80 Hz) frequency ASSR, were compared in 128 patients with schizophrenia, 108 healthy controls, and 55 first-degree relatives (FDR) of patients...
June 20, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28987786/a-simple-model-of-the-inner-hair-cell-ribbon-synapse-accounts-for-mammalian-auditory-nerve-fiber-spontaneous-spike-times
#8
Adam J Peterson, Peter Heil
The initial neural encoding of acoustic information occurs by means of spikes in primary auditory afferents. Each mammalian primary auditory afferent (type-I auditory-nerve fiber; ANF) is associated with only one ribbon synapse in one receptor cell (inner hair cell; IHC). The properties of ANF spike trains therefore provide an indirect view of the operation of individual IHC synapses. We showed previously that a point process model of presynaptic vesicle pool depletion and deterministic exponential replenishment, combined with short postsynaptic neural refractoriness, accounts for the interspike interval (ISI) distributions, serial ISI correlations, and spike-count statistics of a population of cat-ANF spontaneous spike trains...
September 15, 2017: Hearing Research
https://www.readbyqxmd.com/read/28917446/amplitude-modulation-rate-dependent-topographic-organization-of-the-auditory-steady-state-response-in-human-auditory-cortex
#9
Nathan Weisz, Chrysoula Lithari
Periodic modulations of an acoustic feature, such as amplitude over a certain frequency range, leads to phase locking of neural responses to the envelope of the modulation. Using electrophysiological methods this neural activity pattern, also called the auditory steady-state response (aSSR), is visible following frequency transformation of the evoked response as a clear spectral peak at the modulation frequency. Despite several studies employing the aSSR that show, for example, strongest responses for ∼40 Hz and an overall right-hemispheric dominance, it has not been investigated so far to what extent within auditory cortex different modulation frequencies elicit aSSRs at a homogenous source or whether the localization of the aSSR is topographically organized in a systematic manner...
September 11, 2017: Hearing Research
https://www.readbyqxmd.com/read/28887876/cell-specific-gain-modulation-by-synaptically-released-zinc-in-cortical-circuits-of-audition
#10
Charles T Anderson, Manoj Kumar, Shanshan Xiong, Thanos Tzounopoulos
In many excitatory synapses, mobile zinc is found within glutamatergic vesicles and is coreleased with glutamate. Ex vivo studies established that synaptically released (synaptic) zinc inhibits excitatory neurotransmission at lower frequencies of synaptic activity but enhances steady state synaptic responses during higher frequencies of activity. However, it remains unknown how synaptic zinc affects neuronal processing in vivo. Here, we imaged the sound-evoked neuronal activity of the primary auditory cortex in awake mice...
September 9, 2017: ELife
https://www.readbyqxmd.com/read/28857787/stability-of-auditory-steady-state-responses-over-time
#11
Maaike Van Eeckhoutte, Robert Luke, Jan Wouters, Tom Francart
OBJECTIVES: Auditory steady state responses (ASSRs) are used in clinical practice for objective hearing assessments. The response is called steady state because it is assumed to be stable over time, and because it is evoked by a stimulus with a certain periodicity, which will lead to discrete frequency components that are stable in amplitude and phase over time. However, the stimuli commonly used to evoke ASSRs are also known to be able to induce loudness adaptation behaviorally. Researchers and clinicians using ASSRs assume that the response remains stable over time...
August 26, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28855291/the-effect-of-m-current-modulation-on-mammalian-vestibular-responses-to-transient-head-motion
#12
Choongheon Lee, Joseph Christopher Holt, Timothy Arthur Jones
The precise role and mechanisms underlying efferent modulation of peripheral vestibular afferent function are not well understood in mammals. Clarifying the details of efferent action may lead to new strategies for clinical management of debilitating disturbances in vestibular and balance function. Recent evidence in turtle indicates that efferent modulation of M-currents is likely one mechanism for modifying afferent discharge. M-currents depend in part on KCNQ potassium conductances (Kv7) which can be adjusted through efferent activation of M1, M3 and/or M5 muscarinic acetylcholine receptors (mAChRs)...
August 30, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28844789/protocadherin-10-alters-%C3%AE-oscillations-amino-acid-levels-and-their-coupling-baclofen-partially-restores-these-oscillatory-deficits
#13
Russell G Port, Christopher Gajewski, Elizabeth Krizman, Holly C Dow, Shinji Hirano, Edward S Brodkin, Gregory C Carlson, Michael B Robinson, Timothy P L Roberts, Steven J Siegel
Approximately one in 45 children have been diagnosed with Autism Spectrum Disorder (ASD), which is characterized by social/communication impairments. Recent studies have linked a subset of familial ASD to mutations in the Protocadherin 10 (Pcdh10) gene. Additionally, Pcdh10's expression pattern, as well as its known role within protein networks, implicates the gene in ASD. Subsequently, the neurobiology of mice heterozygous for Pcdh10 (Pcdh10(+/-)) has been investigated as a proxy for ASD. Male Pcdh10(+/-) mice have demonstrated sex-specific deficits in social behavior, recapitulating the gender bias observed in ASD...
August 24, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28802870/audio-visual-synchrony-and-spatial-attention-enhance-processing-of-dynamic-visual-stimulation-independently-and-in-parallel-a-frequency-tagging-study
#14
Amra Covic, Christian Keitel, Emanuele Porcu, Erich Schröger, Matthias M Müller
The neural processing of a visual stimulus can be facilitated by attending to its position or by a co-occurring auditory tone. Using frequency-tagging, we investigated whether facilitation by spatial attention and audio-visual synchrony rely on similar neural processes. Participants attended to one of two flickering Gabor patches (14.17 and 17 Hz) located in opposite lower visual fields. Gabor patches further "pulsed" (i.e. showed smooth spatial frequency variations) at distinct rates (3.14 and 3.63 Hz). Frequency-modulating an auditory stimulus at the pulse-rate of one of the visual stimuli established audio-visual synchrony...
August 9, 2017: NeuroImage
https://www.readbyqxmd.com/read/28800744/physiological-artifacts-in-scalp-eeg-and-ear-eeg
#15
Simon L Kappel, David Looney, Danilo P Mandic, Preben Kidmose
BACKGROUND: A problem inherent to recording EEG is the interference arising from noise and artifacts. While in a laboratory environment, artifacts and interference can, to a large extent, be avoided or controlled, in real-life scenarios this is a challenge. Ear-EEG is a concept where EEG is acquired from electrodes in the ear. METHODS: We present a characterization of physiological artifacts generated in a controlled environment for nine subjects. The influence of the artifacts was quantified in terms of the signal-to-noise ratio (SNR) deterioration of the auditory steady-state response...
August 11, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28796603/ear-eeg-based-objective-hearing-threshold-estimation-evaluated-on-normal-hearing-subjects
#16
Christian Bech Christensen, James Michael Harte, Thomas Lunner, Preben Kidmose
OBJECTIVE: Hearing threshold levels have been estimated successfully in the clinic using the objective EEG-based technique of auditory steady state response (ASSR). The recent method of ear-EEG could enable ASSR hearing tests to be made in everyday life, rather than in a specialized clinic, enabling cheaper and easier monitoring of audiometric thresholds over time. The objective of the current study was to evaluate the feasibility of ear-EEG in audiometric characterization of auditory sensitivity thresholds...
August 9, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28756648/objective-assessment-of-hearing-during-second-stage-of-tympanoplasty-surgical-technique-and-measurement-methodology-presented-in-ten-patients
#17
Kazimierz Niemczyk, Krzysztof Morawski, Rafael Delgado, Antoni Bruzgielewicz, Magdalena Lachowska
In this paper, a complete integrated method of intraoperative monitoring of hearing (IOMH) during ossiculoplasty performed via posterior tympanotomy is presented. The method integrates auditory steady state responses (ASSR) with Laser-Doppler Vibrometry (LDV) and allows intraoperative optimization of ossicular prosthesis positioning and coupling. Both ASSR and LDV are acquired simultaneously. The results of the integrated measurements are analyzed and evaluated automatically on-line which makes this strategy unaffected by individual differences in interpretations of collected recordings...
July 30, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28708794/position-of-the-internal-aperture-of-vestibular-aqueduct-in-patients-with-enlarged-vestibular-aqueduct
#18
Huiying Lyu, Juan Hong, Dongming Yin, Keguang Chen, Jieying Li, Lin Yang, Tianyu Zhang, Peidong Dai
OBJECTIVE: To investigate the position of the internal aperture of vestibular aqueduct and its relationship to hearing level in patients with enlarged vestibular aqueduct (EVA). METHODS: The size of the common crus and the position of the internal aperture of vestibular aqueduct were compared among control subjects, EVA patients with and without other inner ear malformations. Auditory steady-state response thresholds were compared between EVA patients with different positions of internal apertures...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28692981/a-new-method-to-test-the-efficiency-of-cochlear-implant-artifacts-removal-from-auditory-evoked-potentials
#19
Virginie Attina, Faten Mina, Pierre Stahl, Yvan Duroc, Evelyne Veuillet, Eric Truy, Hung Thai-Van
Auditory Evoked Potentials (AEPs) are of great interest to objectively evaluate the audition in cochlear implant (CI) recipients. However, these measures are impeded by CI stimulation electrical artifacts present in the EEG. In a first part, this study investigates the use of a hybrid model approximating CI patient data. This model gives access to both uncontaminated and denoised data, thus allowing for the evaluation of CI artifact removal methods. Here the efficiency of Independent Component Analysis (ICA) is evaluated in the context of Auditory Steady State Responses (ASSRs)...
July 6, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28688560/speech-evoked-auditory-brainstem-responses-in-children-with-hearing-loss
#20
Amineh Koravand, Rida Al Osman, Véronique Rivest, Catherine Poulin
OBJECTIVE: The main objective of the present study was to investigate subcortical auditory processing in children with sensorineural hearing loss. METHODS: Auditory Brainstem Responses (ABRs) were recorded using click and speech/da/stimuli. Twenty-five children, aged 6-14 years old, participated in the study: 13 with normal hearing acuity and 12 with sensorineural hearing loss. RESULTS: No significant differences were observed for the click-evoked ABRs between normal hearing and hearing-impaired groups...
August 2017: International Journal of Pediatric Otorhinolaryngology
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