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Systematic review diagnostic

Rui Lian, Guo Chao Zhang, Sheng Tao Yan, Li Chao Sun, Su Qiao Zhang, Guo Qiang Zhang
OBJECTIVE: A new technique of transthoracic lung ultrasonography (TLS) has emerged and demonstrated promising results in acute heart failure diagnosis at an early stage. However, the diagnostic value of ultrasound lung comets (ULCs) for acute heart failure (AHF) performed in busy emergency department (ED) is uncertain. The present meta-analysis aimed to assess the diagnostic efficiency of ULCs in AHF. METHODS: We conducted a search on online journal databases to collect the data on TLS performed for diagnosing AHF published up to the end of July 2017...
August 2018: Biomedical and Environmental Sciences: BES
Rolf Kramer, Marina Sabatier, Thierry Wirth, Maxime Pichon, Bruno Lina, Isabelle Schuffenecker, Laurence Josset
BackgroundUnderstanding enterovirus D68 (EV-D68) circulation patterns as well as risk factors for severe respiratory and neurological illness is important for developing preventive strategies. Methods : Between 2010 and 2016, 11,132 respiratory specimens from hospitalised patients in Lyon, France, were screened for EV-D68 by PCR. Phylogenetic relationships of the viral-protein-1 sequences were reconstructed using maximum-likelihood and Bayesian-Markov-Chain-Monte-Carlo approaches. Results: Overall, 171 infections with a biennial pattern were detected, including seven, one, 55, none, 42, one and 65 cases annually during 2010-16...
September 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
Debashis Sarkar
Introduction The use of mutiparametric MRI (MpMRI) guided fusion biopsy is becoming an increasingly popular investigation in an aid to increase diagnostic yield in those suspected of having prostate cancer (PCa). Before adopting this technology, it is necessary to confirm the accuracy, so that PCa can be reliably diagnosed with characterisation. Materials and Methods This chapter analysed the evidences, which varied from well-designed randomised controlled trials to case series to detect the accuracy of MpMRI compared with biopsy/ histology...
2018: Advances in Experimental Medicine and Biology
Asta Agasarova, Clare Harnett, Niall Mulligan, Muhammad Shakeel Majeed, Alberto Caimo, Gianluca Tamagno
Bronchial neuroendocrine tumors (NET) are classified into well-differentiated typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas (LCNEC), and small cell lung carcinomas (SCLC). We retrospectively reviewed and analyzed the diagnostic and therapeutic aspects, follow-up data, and outcomes of all patients diagnosed with a bronchial NET from 1995 to 2015 at our institution. Patients with LCNEC or SCLC were excluded due to the biological and clinical differences from the other bronchial NET...
2018: International Journal of Endocrinology
Aodhnait S Fahy, Agostino Pierro
INTRODUCTION:  With improvements in prenatal ultrasound, more abdominal enteric duplication cysts (EDCs) are diagnosed prenatally. The optimal time for operative intervention is unclear. We aimed to review the evidence supporting the indication and timing of surgery for prenatally diagnosed EDCs. MATERIALS AND METHODS:  A systematic review was performed using a defined search strategy identifying articles with inclusion criteria of prenatal diagnosis of histologically confirmed EDCs...
September 18, 2018: European Journal of Pediatric Surgery
Rafael Tostes Muniz, Evandro Tinoco Mesquita, Celso Vale Souza Junior, Wolney de Andrade Martins
Pulmonary congestion is an important clinical finding in patients with heart failure (HF). Physical examination and chest X-ray have limited accuracy in detecting congestion. Pulmonary ultrasound (PU) has been incorporated into clinical practice in the evaluation of pulmonary congestion. This paper aimed to perform a systematic review of the use of PU in patients with HF, in different scenarios. A search was performed in the MEDLINE and LILACS databases in February 2017 involving articles published between 2006 and 2016...
June 2018: Arquivos Brasileiros de Cardiologia
Bo Hyun Kim, Seong-Jang Kim, Mijin Kim, Sang-Woo Lee, Shin Young Jeong, Kyoungjune Pak, Keunyoung Kim, In Joo Kim
OBJECTIVE: The purpose of the current study was to investigate the diagnostic performance of high mobility group A2 (HMGA2) gene expression for differentiation of malignant thyroid nodules through a systematic review and meta-analysis. DESIGN: The MEDLINE/PubMed and EMBASE database, from the earliest available date of indexing through April 10, 2018, were searched for studies evaluating the diagnostic performance of HMGA2 expression for differentiation of thyroid nodules...
September 17, 2018: Clinical Endocrinology
Evangelia Valilis, Alison Ramsey, Saad Sidiq, Herbert L DuPont
Non-O157 strains of STEC are more common causes of acute diarrhea than the better-known O157 strains and have the potential for large outbreaks. This systematic review of the literature identified 129 serogroups as well as 262 different O and H antigen combinations of Shiga-toxin-producing Escherichia coli (STEC) in cases of epidemic and sporadic disease worldwide. Removing results from a single large outbreak of STEC O104:H4 in Germany and France in 2011, the reported frequency of dysenteric illness in patients was 119 of 464 (26%) for epidemic disease and 646 of 2,588 (25%) for sporadic cases...
September 14, 2018: International Journal of Infectious Diseases: IJID
Shahriar Zehtabchi, Daniel Michael Fatovich
In this issue of the Academic Emergency Medicine, Viau et al.1 assess the yield of computed tomography (CT) of the head among patients presenting with syncope. The systematic review included a total of 17 studies (15 retrospective chart reviews and 2 prospective) that included adult ED patients presenting with the chief complaint of syncope or those admitted to the hospital for syncope. Approximately half of these ED patients underwent head CT with a 1.2% and 3.8% yield of serious intracranial conditions identified in admitted patients and emergency department patients, respectively...
September 17, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
Anne Duffy, Naomi Heffer, Sarah M Goodday, Arielle Weir, Scott Patten, Gin S Malhi, Andrea Cipriani
OBJECTIVES: To assess the efficacy and tolerability of lithium for the treatment of acute mania in children and adolescent diagnosed with bipolar disorder. METHODS: A systematic literature search up to August 2017 was conducted for clinical trials that included lithium in males and females up to 18 years of age with a diagnosis of bipolar disorder and experiencing a manic or mixed episode according to standardized diagnostic criteria. The protocol was registered in PROSPERO (CRD42017055675)...
September 16, 2018: Bipolar Disorders
Elizabeth S Mearns, Aliki Taylor, Talia Boulanger, Kelly J Craig, Michele Gerber, Daniel A Leffler, Jennifer Drahos, David S Sanders, Benjamin Lebwohl
BACKGROUND: The prevalence of celiac disease (CD) has rapidly increased over recent decades, but costs related to CD remain poorly quantified. OBJECTIVE: This systematic review assessed the economic burden of CD in North America and Europe. METHODS: MEDLINE, EMBASE, EconLit, and the Cochrane Library databases were systematically searched to identify English-language literature from 2007 to 2018 that assessed costs, cost effectiveness, and health resource utilization for CD...
September 17, 2018: PharmacoEconomics
Lijun Wang, Ronghui Wang, Hua Wei, Yanbin Li
Aptamers are short nucleotide sequences which can specifically bind to a variety of targets with high affinity. They are identified and selected via systematic evolution of ligands by exponential enrichment (SELEX). Compared to antibodies, aptamers offer several advantages including easy labeling, high stability and lower cost. Those advantages make it possible to be a potential for use as a recognition probe to replace antibody in the diagnostic field. This article is intended to provide a comprehensive review, which is focused on systemizing recent advancements concerning SELEX procedures, with special emphasis on the key steps in SELEX procedures...
September 15, 2018: World Journal of Microbiology & Biotechnology
Csilla Celeng, Tim Leiner, Pál Maurovich-Horvat, Béla Merkely, Pim de Jong, Jan W Dankbaar, Hendrik W van Es, Brian B Ghoshhajra, Udo Hoffmann, Richard A P Takx
OBJECTIVES: This meta-analysis determined the diagnostic performance of coronary computed tomography (CT) angiography (CTA), CT myocardial perfusion (CTP), fractional flow reserve CT (FFRCT ), the transluminal attenuation gradient (TAG), and their combined use with CTA versus FFR as a reference standard for detection of hemodynamically significant coronary artery disease (CAD). BACKGROUND: CTA provides excellent anatomic, albeit limited functional information for the evaluation of CAD...
September 6, 2018: JACC. Cardiovascular Imaging
Titus H Divala, Katherine L Fielding, Marriott Nliwasa, Derek J Sloan, Ankur Gupta-Wright, Elizabeth L Corbett
BACKGROUND: Suboptimal diagnostics for pulmonary tuberculosis (PTB) drives use of 'trial-of-antibiotics (non-tuberculosis)' in an attempt to distinguish PTB patients from those with bacterial lower respiratory tract infection (LRTI). The underlying assumption-that patients with LRTI will report 'response' to broad-spectrum antibiotics, while those with PTB will not-has minimal evidence base for such a widely used intervention. Numerous potential causes of misclassification include bacterial super-infection of active PTB, placebo effect, and antimicrobial resistance (AMR)...
September 15, 2018: Systematic Reviews
Jillian McCarthy, D Louis Collins, Simon Ducharme
Frontotemporal dementia (FTD) is difficult to diagnose, due to its heterogeneous nature and overlap in symptoms with primary psychiatric disorders. Brain MRI for atrophy is a key biomarker but lacks sensitivity in the early stage. Morphometric MRI-based measures and machine learning techniques are a promising tool to improve diagnostic accuracy. Our aim was to review the current state of the literature using morphometric MRI to classify FTD and assess its applicability for clinical practice. A search was completed using Pubmed and PsychInfo of studies which conducted a classification of subjects with FTD from non-FTD (controls or another disorder) using morphometric MRI metrics on an individual level, using single or combined approaches...
August 31, 2018: NeuroImage: Clinical
Caitlin Wilson, Clare Harley, Stephanie Steels
INTRODUCTION: Paramedics are involved in examining, treating and diagnosing patients. The accuracy of these diagnoses is evaluated using diagnostic accuracy studies. We undertook a systematic review of published literature to provide an overview of how accurately paramedics diagnose patients compared with hospital doctors. A bivariate meta-analysis was incorporated to examine the range of diagnostic sensitivity and specificity. METHODS: We searched MEDLINE, CINAHL, Embase, AMED and the Cochrane Database from 1946 to 7 May 2016 for studies where patients had been given a diagnosis by paramedics and hospital doctors...
September 14, 2018: Emergency Medicine Journal: EMJ
Emmanuel Grellety, Michael H Golden
BACKGROUND: The WHO recommended criteria for diagnosis of sever acute malnutrition (SAM) are weight-for-height/length Z-score (WHZ) of <- 3Z of the WHO2006 standards, a mid-upper-arm circumference (MUAC) of < 115 mm, nutritional oedema or any combination of these parameters. A move to eliminate WHZ as a diagnostic criterion has been made on the assertion that children with a low WHZ are healthy, that MUAC is a "superior" prognostic indicator of mortality and that adding WHZ to the assessment does not improve the prediction of death...
September 15, 2018: Nutrition Journal
Michele Fornaro, Domenico De Berardis, Annalisa Anastasia, Stefano Novello, Andrea Fusco, Carlo Ignazio Cattaneo, Marco Solmi, Francesco Monaco, Nicola Veronese, Yong-Ku Kim, Andrea de Bartolomeis
The prediction of acute and maintenance lithium treatment response carries major clinical and neurobiological implications, warranting systematic review. A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) compliant review searched major electronic databases from inception until December 2017 for studies documenting a clinical diagnosis of bipolar disorder (BD) made according to the mainstream diagnostic manuals and confirmed by a structured interview. Eligible studies allowed a quantitative comparison of endpoint vs baseline mean values of a given biomarker, regardless of the mood phase of patients with BD, and the disorder was assessed for severity using validated rating tool(s)...
August 16, 2018: Psychiatry Research
Niels Lynøe, Anders Eriksson
The main conclusion of the SBU systematic review was that there is insufficient scientific evidence on which to assess the diagnostic accuracy of the triad in identifying traumatic shaking (very low-quality evidence) (1). Laurent-Vannier et al are concerned that this conclusion is used by defence lawyers, but this concern can be understood and respected only if the review was actually flawed (2). The authors duplicate the claims of Debelle et al (3) that the review contains significant flaws and that it should be retracted...
September 14, 2018: Acta Paediatrica
Irene Prabhu Das, Melanie Baker, Cheryl Altice, Kathleen M Castro, Barbara Brandys, Sandra A Mitchell
Multidisciplinary treatment planning (MTP) is a process of engaging multiple disciplines to develop or refine the disease management plan. It is widely implemented in US cancer treatment settings and is considered to have favorable effects on both care quality and other outcomes. However, evidence reviews to date regarding MTP effectiveness have based their conclusions on studies conducted predominantly outside the United States. The authors conducted a systematic review of US-based studies to synthesize and critically appraise evidence of the effects of MTP on cancer care quality, health services outcomes, and survival...
September 14, 2018: Cancer
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