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diabetes and infections

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https://www.readbyqxmd.com/read/29145535/atypical-microbial-isolates-from-infected-diabetic-foot-ulcers-a-case-series-from-greece
#1
Maria Demetriou, Nikolaos Papanas, Periklis Panagopoulos, Maria Panopoulou, Efstratios Maltezos
No abstract text is available yet for this article.
July 2017: Review of Diabetic Studies: RDS
https://www.readbyqxmd.com/read/29143906/surgery-for-diverticular-disease-results-in-a-higher-hernia-rate-compared-to-colorectal-cancer-a-population-based-study-from-ontario-canada
#2
E S Tang, D I Robertson, M Whitehead, J Xu, S F Hall
BACKGROUND: Incisional hernias are a well described complication of abdominal surgery. Previous studies identified malignancy and diverticular disease as risk factors. We compared incisional hernia rates between colon resection for colorectal cancer (CRC) and diverticular disease (DD). STUDY DESIGN: We performed a retrospective, population-based, matched cohort study. Provincial databases were linked through the Institute for Clinical Evaluative Sciences. These databases include all patients registered under the universal Ontario Health Insurance Plan...
November 16, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29143639/linking-household-surveys-and-health-facility-assessments-to-estimate-intervention-coverage-for-the-lives-saved-tool-list
#3
Mufaro Kanyangarara, Victoria B Chou
BACKGROUND: Calls have been made for improved measurement of coverage for maternal, newborn and child health interventions. Recently, methods linking household and health facility surveys have been used to improve estimation of intervention coverage. However, linking methods rely the availability of household and health facility surveys which are temporally matched. Because nationally representative health facility assessments are not yet routinely conducted in many low and middle income countries, estimates of intervention coverage based on linking methods can be produced for only a subset of countries...
November 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29142978/severe-adverse-effects-associated-with-corticosteroid-treatment-in-patients-with-iga-nephropathy
#4
Qingqing Cai, Xinfang Xie, Jinwei Wang, Sufang Shi, Lijun Liu, Yuqing Chen, Jicheng Lv, Hong Zhang
Introduction: Few data are available on the risk of SAEs in corticosteroid users in IgAN populations. We describe the prevalence and risk factors of corticosteroid-related SAEs in a Chinese cohort. Methods: A total of 1034 IgAN patients were followed up in our renal center from 2003 to 2014. Prevalence of corticosteroid use and corticosteroid-related SAEs were noted. Logistic regression was used to search for risk factors of SAEs in corticosteroid users. Results: Of the 369 patients with steroids therapy, 46 patients (12...
July 2017: KI Reports
https://www.readbyqxmd.com/read/29142540/clinical-audit-of-dengue-related-deaths-in-2011-mayo-hospital-lahore-pakistan
#5
Somia Iqtadar, Nabeel Akbar, Mehreen Mehmood, Sajid Abaidullah
Background and Objective: Dengue infection has evolved into an epidemic during last few years in Pakistan and has been associated with poor outcomes. Literature with respect to mortality risk factors in Dengue infection is not sufficient. This compelled us to conduct this study to find out major contributory factors to death in patients with dengue viral infection at one of Asia's ancient hospital setting with an aim to recognize complications at earliest and improve case management in future...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29142443/oral-health-and-erectile-dysfunction
#6
REVIEW
Vijendra P Singh, Sunil K Nettemu, Sowmya Nettem, Rajesh Hosadurga, Sangeeta U Nayak
Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment...
July 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29141925/unusual-salmonella-typhi-periprosthetic-joint-infection-involving-bilateral-knees-management-options-and-literature-review
#7
Ashok Rajgopal, Inayat Panda, Anu Gupta
A 70-year-old Indian woman, who had undergone primary bilateral total knee arthroplasty (TKA) for rheumatoid arthritis 10 months prior, presented with 10 days history of pain, swelling and erythema over both knees with pus discharging from the right knee. She had type 2 diabetes mellitus and was on long-term steroid, leflunomide and antitumour necrosis factor therapy for rheumatoid arthritis. Her clinical and laboratory features were suggestive of a haematogenous periprosthetic joint infection (PJI). The final diagnosis of bilateral Salmonella typhi PJI was made based on culture reports...
November 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29141856/impact-of-diabetes-mellitus-on-outcomes-in-patients-supported-with-left-ventricular-assist-devices-a-single-institutional-9-year-experience
#8
Rabea Asleh, Alexandros Briasoulis, Sarah D Schettle, Vakhtang Tchantchaleishvili, Naveen L Pereira, Brooks S Edwards, Alfredo L Clavell, Simon Maltais, David L Joyce, Lyle D Joyce, Richard C Daly, Sudhir S Kushwaha, John M Stulak
BACKGROUND: Diabetes mellitus (DM) is a risk factor for morbidity and mortality in patients with heart failure. The effect of DM on post-left ventricular assist device (LVAD) implantation outcomes is unclear. This study sought to investigate whether patients with DM had worse outcomes than patients without DM after LVAD implantation and whether LVAD support resulted in a better control of DM. METHODS AND RESULTS: We retrospectively reviewed 341 consecutive adults who underwent implantation of LVAD from 2007 to 2016...
November 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29141759/cell-type-specific-immunomodulation-induced-by-helminthes-effect-on-metainflammation-insulin-resistance-and-type-2-diabetes
#9
Vivekanandhan Aravindhan, Gowrishankar Anand
Recent epidemiological studies have documented an inverse relationship between the decreasing prevalence of helminth infections and the increasing prevalence of metabolic diseases ("metabolic hygiene hypothesis"). Chronic inflammation leading to insulin resistance (IR) has now been identified as a major etiological factor for a variety of metabolic diseases other than obesity and Type-2 diabetes (metainflammation). One way by which helminth infections such as filariasis can modulate IR is by inducing a chronic, nonspecific, low-grade, immune suppression mediated by modified T-helper 2 (Th2) response (induction of both Th2 and regulatory T cells) which can in turn suppress the proinflammatory responses and promote insulin sensitivity (IS)...
October 30, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29139617/world-s-smallest-combined-en-bloc-liver-pancreas-transplantation
#10
Ahmed M Elsabbagh, Jason Hawksworth, Khalid M Khan, Nada Yazigi, Cal S Matsumoto, Thomas M Fishbein
We present a case of a 2-year-old child who underwent a combined en bloc liver and pancreas transplant following complications of WRS. WRS is characterized clinically through infantile insulin-dependent diabetes mellitus, neutropenia, recurrent infections, propensity for liver failure following viral infections, bone dysplasia, and developmental delay. Usually, death occurs from fulminant liver and concomitant kidney failure. Few cases with WRS are reported in the literature, mostly from consanguineous parents...
November 15, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29139559/associations-among-tooth-loss-systemic-inflammation-and-antibody-titers-to-periodontal-pathogens-in-japanese-patients-with-cardiovascular-disease
#11
N Aoyama, J-I Suzuki, N Kobayashi, T Hanatani, N Ashigaki, A Yoshida, Y Shiheido, H Sato, M Minabe, Y Izumi, M Isobe
BACKGROUND AND OBJECTIVE: It is well known that there is a strong relationship between periodontitis and cardiovascular disease (CVD). Tooth loss reflects an end-stage condition of oral diseases, such as periodontitis. Infection with specific periodontal pathogens is known as a possible factor that influences development of CVD. The aim of this study was to assess the relationship between the number of residual teeth and systemic inflammatory conditions in patients with CVD. MATERIAL AND METHODS: We divided 364 patients with CVD into four groups, according to the number of residual teeth: (i) ≥20 teeth; (ii) 10-19 teeth; (iii) 1-9 teeth; and (iv) edentulous...
November 15, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29138839/sumo1-ubc9%C3%A2-decreased-nox1-activity-inhibits-reactive-oxygen-species-generation-and-apoptosis-in-diabetic-retinopathy
#12
Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Diabetic retinopathy (DR) is an increasing global health concern that causes vision loss and blindness. Reactive oxygen species (ROS) are considered to be a principal cause of DR. An important source of ROS is the oxidization of NADPH. In the present study, NADPH oxidase 1 (Nox1)‑expressing human retinal epithelial cell (HREC) lines were generated and infected with small ubiquitin‑like modifier 1 (SUMO1) and/or ubiquitin conjugating enzyme E2 I (UBC9) lentiviral pGMLV constructs. The viabilities, apoptotic capacities and ROS production levels of the HREC lines were quantified using Hoechst 33258, annexin V/propidium iodide and dichlorodihydrofluorescein diacetate assays, respectively...
November 13, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29138622/antimicrobial-efficacy-of-penicillium-amestolkiae-elv609-extract-treated-cotton-fabric-for-diabetic-wound-care
#13
Nur Amiera Syuhada Binti Rozman, Nurhanis Syafiqah Binti Mohd Nor Hamin, Leong Chean Ring, Tan Wen Nee, Mahfuzah Binti Mustapha, Tong Woei Yenn
Diabetes mellitus is a chronic disorder which affects millions of population worldwide. Global estimates published in 2010 reported the world diabetic prevalence as 6.4%, affecting 285 million adults. Foot ulceration and wound infection are major forms of disabilities arising from diabetic diseases. This study was aimed to develop a natural antimicrobial finishing on medical grade textile that meets American Association of Textiles Chemists and Colorists (AATCC) standard. The textile samples were finished with the ethanolic extract of Penicillium amestolkiae elv609, an endophytic fungus isolated from Orthosiphon stamineus Benth (common name: cat's whiskers)...
September 2017: Mycobiology
https://www.readbyqxmd.com/read/29138583/efficacy-of-intravenous-tigecycline-in-patients-with-acinetobacter-complex-infections-results-from-14-phase-iii-and-phase-iv-clinical-trials
#14
Hal Tucker, Michele Wible, Ashesh Gandhi, Alvaro Quintana
Background: Acinetobacter infections, especially multidrug-resistant (MDR) Acinetobacter infections, are a global health problem. This study aimed to describe clinical outcomes in patients with confirmed Acinetobacter spp. isolates who were treated with tigecycline in randomized clinical trials. Materials and methods: Data from 14 multinational, randomized (open-label or double-blind), and active-controlled (except one) Phase III and IV studies were analyzed using descriptive statistics...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29138182/disparities-in-the-quality-of-cardiovascular-care-between-hiv-infected-versus-hiv-uninfected-adults-in-the-united-states-a-cross-sectional-study
#15
Joseph A Ladapo, Adam K Richards, Cassandra M DeWitt, Nina T Harawa, Steven Shoptaw, William E Cunningham, John N Mafi
BACKGROUND: Cardiovascular disease is emerging as a major cause of morbidity and mortality among patients with HIV. We compared use of national guideline-recommended cardiovascular care during office visits among HIV-infected versus HIV-uninfected adults. METHODS AND RESULTS: We analyzed data from a nationally representative sample of HIV-infected and HIV-uninfected patients aged 40 to 79 years in the National Ambulatory Medical Care Survey/National Hospital Ambulatory Medical Care Survey, 2006 to 2013...
November 14, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29136732/-prognosis-factors-for-the-perineal-incision-complications-after-abdominoperineal-resection-for-low-rectal-cancer
#16
S Luo, J W Liang, H T Zhou, W Pei, Z X Zhou, Q Liu, X S Wang
Objective: To evaluate the prognosis factors affecting perineal incision complications after abdominoperineal resection (APR) for the low rectal cancer. Methods: This was a retrospective analysis of 151 consecutive patients with low rectal cancer undergoing APR between January and December 2013 at Department of Colorectal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. The patients were comprised of 95 males and 56 females. The mean age of the patients was (57...
November 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29136618/hepcidin-in-iron-homeostasis-diagnostic-and-therapeutic-implications-in-type-2-diabetes-mellitus-patients
#17
Sintayehu Ambachew, Belete Biadgo
The prevalence of type 2 diabetes is increasing in epidemic proportions worldwide. Evidence suggests body iron overload is frequently linked and observed in patients with type 2 diabetes. Body iron metabolism is based on iron conservation and recycling by which only a part of the daily need is replaced by duodenal absorption. The principal liver-produced peptide called hepcidin plays a fundamental role in iron metabolism. It directly binds to ferroportin, the sole iron exporter, resulting in the internalization and degradation of ferroportin...
November 15, 2017: Acta Haematologica
https://www.readbyqxmd.com/read/29136263/treatment-of-scleroedema-adultorum-buschke-a-systematic-review
#18
Diana Miguel, Sibylle Schliemann, Peter Elsner
Scleroedema adultorum Buschke is a rare skin disease, which can be divided into 3 subtypes: "classic type", occurring after respiratory infections; a type lacking association with infections; and a type associated with diabetes. Scleroedema adultorum Buschke is characterized by thickening and tightening of the skin, which typically starts at the neck. In half of patients, spontaneous remission may occur. The aim of this systematic review is to summarize all reported treatments for scleroedema adultorum Buschke, based on articles from PubMed database, using the query "scleroedema adultorum Buschke treatment", English and German, published between 1970 and 2016 and documenting adequate treatments...
November 14, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29135663/serum-fructosamine-a-simple-and-inexpensive-test-for-assessing-preoperative-glycemic-control
#19
Noam Shohat, Majd Tarabichi, Eric H Tischler, Serge Jabbour, Javad Parvizi
BACKGROUND: Although the medical community acknowledges the importance of preoperative glycemic control, the literature is inconclusive and the proper metric for assessment of glycemic control remains unclear. Serum fructosamine reflects the mean glycemic control in a shorter time period compared with glycated hemoglobin (HbA1c). Our aim was to examine its role in predicting adverse outcomes following total joint arthroplasty. METHODS: Between 2012 and 2013, we screened all patients undergoing total joint arthroplasty preoperatively using serum HbA1c, fructosamine, and blood glucose levels...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29135581/high-rates-of-hypertension-diabetes-elevated-low-density-lipoprotein-cholesterol-and-cardiovascular-disease-risk-factors-in-hiv-infected-patients-results-from-a-cross-sectional-survey-in-malawi
#20
Sekai C Mathabire Rücker, Alia Tayea, Joseph Bitilinyu-Bangoh, Elkin H Bermúdez-Aza, Leon Salumu, Isabel A Quiles, Elisabeth Szumilin, Zengani Chirwa, Fernanda Rick, David Maman
OBJECTIVES: Data on cardiovascular disease risks among HIV-infected patients taking antiretroviral therapy (ART) over long periods of time are lacking in Sub-Saharan Africa. METHODS: A cross-sectional study was conducted in Chiradzulu, Malawi from December 2015 to June 2016. HIV-infected persons on ART for more than 10 years (patients) and HIV-negative individuals (controls) from selected clinics participated. Following informed consent, a standardized questionnaire, clinical and laboratory examinations were performed...
November 10, 2017: AIDS
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