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https://www.readbyqxmd.com/read/28933880/media-exposure-in-very-young-girls-prospective-and-cross-sectional-relationships-with-bmiz-self-esteem-and-body-size-stereotypes
#1
Rachel F Rodgers, Stephanie R Damiano, Eleanor H Wertheim, Susan J Paxton
Media exposure among young children has been suggested to influence self-concept and the adoption of social stereotypes regarding body weight, as well as being associated with increased weight. The aim of this study was to examine the role of TV/DVD viewing in the development of positive stereotypes toward thinness, self-esteem and body mass index standardized for child age and gender (BMIz) in very young girls. A sample of 143 girls completed interviews at ages 3, 4, and 5 years old. The interviews assessed positive stereotypes about thinness among girls, as well as age 5 dietary restraint...
September 21, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28933095/-investigation-of-effects-of-albiflorin-and-paeoniflorin-on-hippocampal-bdnf-and-no-in-chronic-restraint-stress-rats
#2
Ying-Li Zhu, Lin-Yuan Wang, Cheng-Long Wang, Dan-Ping Zhao, Sha Wang, Wen-Ting Fei, Jian-Jun Zhang
This paper aimed to investigate the antidepressant-like effects and the mechanism of the albiflorin, paeoniflorin on rats with chronic restraint stress model. Fluoxetine and Xiaoyao group served as the positive control, body weight, sucrose preference test and the open field behavioral experiment were measured, the levels of nitric oxide (NO) in hippocampus were detected by Greg colorimetric method. Furthermore, the levels of brain derived neurotrophic factor (BDNF) in hippocampus were detected by ELISA. Finally, the expressions of nNOS mRNA in hippocampus detected by RT-qPCR, the protein levels of nNOS and BDNF in hippocampus were detected by Western blot...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28932185/hyperactivity-of-hypothalamic-pituitary-adrenal-axis-due-to-dysfunction-of-the-hypothalamic-glucocorticoid-receptor-in-sigma-1-receptor-knockout-mice
#3
Tingting Di, Suyun Zhang, Juan Hong, Tingting Zhang, Ling Chen
Sigma-1 receptor knockout (σ1R-KO) mice exhibit a depressive-like phenotype. Because σ1R is highly expressed in the neuronal cells of hypothalamic paraventricular nuclei (PVN), this study investigated the influence of σ1R deficiency on the regulation of the hypothalamic-pituitary-adrenocortical (HPA) axis. Here, we show that the levels of basal serum corticosterone (CORT), adrenocorticotropic hormone (ACTH) and corticotrophin releasing factor (CRF) as well as the level of CRF mRNA in PVN did not significantly differ between adult male σ1R-KO mice and wild-type (WT) mice...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28932080/comparison-between-tocotrienol-and-omeprazole-on-gastric-growth-factors-in-stress-exposed-rats
#4
Mohd Fahami Nur Azlina, Hj Mohd Saad Qodriyah, Kien Hui Chua, Yusof Kamisah
AIM: To investigate and compare the effects of tocotrienol and omeprazole on gastric growth factors in rats exposed to water-immersion restraint stress (WIRS). METHODS: Twenty-eight male Wistar rats were randomly assigned to four groups of seven rats. The two control groups were administered vitamin-free palm oil (vehicle) and the two treatment groups were given omeprazole (20 mg/kg) or tocotrienol (60 mg/kg) by oral gavage. After 28 d of treatment, rats from one control group and both treated groups were subjected to WIRS one time for 3...
August 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28928195/reach-study-protocol-of-a-randomised-trial-of-rehabilitation-very-early-in-congenital-hemiplegia
#5
Roslyn N Boyd, Jenny Ziviani, Leanne Sakzewski, Iona Novak, Nadia Badawi, Kerstin Pannek, Catherine Elliott, Susan Greaves, Andrea Guzzetta, Koa Whittingham, Jane Valentine, Cathy Morgan, Margaret Wallen, Ann-Christin Eliasson, Lisa Findlay, Robert Ware, Simona Fiori, Stephen Rose
OBJECTIVES: Congenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial...
September 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28928002/association-between-seatbelt-sign-and-internal-injuries-in-the-contemporary-airbag-era-a-retrospective-cohort-study
#6
Julie M Glover, Madelyn F Waychoff, Monica Casmaer, Michael D April, Curtis J Hunter, Scott T Trexler, Lorne H Blackbourne
BACKGROUND: Literature predating routine availability of airbags reported an association between seatbelt signs and internal injuries. We measured this association among patients involved in motor vehicle crashes (MVCs) with airbag deployment. METHODS: We conducted a retrospective cohort study by chart review of all MVC patients presenting to our Emergency Department (ED) during 1 January 2008-30 September 2015. We included all adult MVC patients in the driver or front passenger seats with both shoulder and lap seatbelts and airbag deployment...
September 12, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28925408/liver-volume-and-hepatic-adiposity-in-childhood-relations-to-body-growth-and-visceral-fat
#7
R Malpique, J Bassols, A López-Bermejo, M Diaz, F Villarroya, J Pavia, A Congo, F de Zegher, L Ibáñez
BACKGROUND AND OBJECTIVE: The sequence of prenatal growth restraint and postnatal catch-up growth may lead to hepato-visceral adiposity, insulin resistance and low-grade inflammation before the onset of puberty. In prepubertal children born appropriate for gestational age (AGA) or small for gestational age (SGA), we assessed potential relationships between the aforementioned sequence and liver volume. SUBJECTS/METHODS: The study population consisted of 86 children (41 AGA and 45 SGA with catch-up growth; age (mean±s...
August 14, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28925357/restraint-of-presynaptic-protein-levels-by-wnd-dlk-signaling-mediates-synaptic-defects-associated-with-the-kinesin-3-motor-unc-104
#8
Jiaxing Li, Yao V Zhang, Elham Asghari Adib, Doychin T Stanchev, Xin Xiong, Susan Klinedinst, Pushpanjali Soppina, Thomas Robert Jahn, Richard I Hume, Tobias M Rasse, Catherine A Collins
The kinesin-3 family member Unc-104/KIF1A is required for axonal transport of many presynaptic components to synapses, and mutation of this gene results in synaptic dysfunction in mice, flies and worms. Our studies at the Drosophila neuromuscular junction indicate that many synaptic defects in unc-104-null mutants are mediated independently of Unc-104's transport function, via the Wallenda (Wnd)/DLK MAP kinase axonal damage signaling pathway. Wnd signaling becomes activated when Unc-104's function is disrupted, and leads to impairment of synaptic structure and function by restraining the expression level of active zone (AZ) and synaptic vesicle (SV) components...
September 19, 2017: ELife
https://www.readbyqxmd.com/read/28924642/breastfeeding-un-covered-narratives-of-public-breastfeeding-on-romanian-discussion-forums
#9
Diana Tăut
PURPOSE: The aim of this study was to explore the construction of breastfeeding in public, as depicted in the stories and the opinions of women participating in discussions on public forums. METHOD: There were 8 discussion forums selected, from which 769 messages were subjected to a narrative analysis further informed by recurrent themes identified in the literature and across messages. The emerging narratives were grouped based on their valence, and three broader categories of themes were formed, highlighting the predominant tone towards breastfeeding in public...
September 18, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28923960/igh-isotype-specific-b-cell-receptor-expression-influences-b-cell-fate
#10
Pei Tong, Alessandra Granato, Teng Zuo, Neha Chaudhary, Adam Zuiani, Seung Seok Han, Rakesh Donthula, Akritee Shrestha, Debattama Sen, Jennifer M Magee, Michael P Gallagher, Cees E van der Poel, Michael C Carroll, Duane R Wesemann
Ig heavy chain (IgH) isotypes (e.g., IgM, IgG, and IgE) are generated as secreted/soluble antibodies (sIg) or as membrane-bound (mIg) B cell receptors (BCRs) through alternative RNA splicing. IgH isotype dictates soluble antibody function, but how mIg isotype influences B cell behavior is not well defined. We examined IgH isotype-specific BCR function by analyzing naturally switched B cells from wild-type mice, as well as by engineering polyclonal Ighγ1/γ1 and Ighε/ε mice, which initially produce IgG1 or IgE from their respective native genomic configurations...
September 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28920794/intraocular-pressure-and-examination-findings-in-three-species-of-central-and-south-american-tree-frogs-cruziohyla-craspedopus-cruziohyla-calcarifer-and-anotheca-spinosa
#11
Andrew C Lewin, Jennifer C Hausmann, Paul E Miller
The purpose of this prospective study was to describe intraocular pressure (IOP) and examination findings in three tree frog species (Cruziohyla craspedopus [fringe leaf frog], Cruziohyla calcarifer [splendid leaf frog], and Anotheca spinosa [spiny-headed or coronated tree frog]). Thirty-one C. craspedopus, four C. calcarifer, and five A. spinosa were weighed, sexed based on phenotype where possible, and examined using slit-lamp biomicroscopy and indirect ophthalmoscopy. IOP was measured using the TonoVet and TonoLab rebound tonometers while the frogs were held two ways (unrestrained, then restrained)...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28918771/falls-in-hospitalized-geriatric-psychiatry-patients-high-incidence-but-only-a-few-fractures
#12
Dennis Oepen, Tim Fleiner, Andrés Oliva Y Hausmann, Susanne Zank, Wiebren Zijlstra, Peter Haeussermann
Fall rates from 3.2 to 17.1 falls per 1,000 hospital days in geriatric psychiatry facilities have been reported to date. Up to 5% of the falls result in severe injuries, but data concerning medical consequences are scare. This brief report presents a retrospective analysis of one year fall protocols from a geriatric psychiatry department focusing on consequences of falls. Fall-induced injuries were rated in four categories: no injuries, mild injuries (contusions, hematomas, abrasions), moderate injuries (lacerations, dislocations), and severe injuries (fractures, cerebral hemorrhages)...
September 18, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28918223/an-ecological-model-to-factors-associated-with-booster-seat-use-a-population-based-study
#13
Sarit Shimony Kanat, Rosa Gofin
Belt-positioning booster seat use (BPB) is an effective technology to prevent severe child injury in cases of car crash. However, in many countries, age-appropriate car restraint use for children aged 4-7 years old remains the lowest among all age groups. The aim of this study was to identify the main determinants of BPB use through a comprehensive approach. An ecological model was used to analyze individual, parent-child relationships, and neighborhood characteristics. Parents of children enrolled in the first and second grades completed a self-reported questionnaire (n=745)...
September 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28918093/topological-structure-determination-of-rna-using-small-angle-x-ray-scattering
#14
Yuba R Bhandari, Linxin Fan, Xianyang Fang, George Zaki, Eric A Stahlberg, Wei Jiang, Charles D Schwieters, Jason R Stagno, Yun-Xing Wang
Knowledge of RNA three-dimensional topological structures provides important insight into the relationship between RNA structural components and function. It is often likely that near complete sets of biochemical and biophysical data containing structural restraints are not available but one still wants to obtain knowledge about approximate topological folding of RNA. In this regard, general methods for determining such topological structures with minimum readily available restraints are lacking. Naked RNAs are difficult to crystallize and NMR spectroscopy is generally limited to small RNA fragments...
September 13, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28916246/pre-clinical-toxicology-considerations-for-vaccine-development
#15
REVIEW
Nabil Al-Humadi
Vaccine development requires pre-clinical toxicology studies, following good laboratory practice (GLP), before first in human (phase I) use. Many factors are critical in the final outcome of any pre-clinical toxicology study. The study design is one of these critical factors and should be carefully planned to avoid any false negative and/or false positive results. Preparation is another most critical factor in a successful study. Major changes in any procedure during the course of study should be avoided by all means...
September 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28915909/differential-signal-sensitivities-can-contribute-to-the-stability-of-multispecies-bacterial-communities
#16
János Juhász, Dóra Bihary, Attila Jády, Sándor Pongor, Balázs Ligeti
BACKGROUND: Bacterial species present in multispecies microbial communities often react to the same chemical signal but at vastly different concentrations. The existence of different response thresholds with respect to the same signal molecule has been well documented in quorum sensing which is one of the best studied inter-cellular signalling mechanisms in bacteria. The biological significance of this phenomenon is still poorly understood, and cannot be easily studied in nature or in laboratory models...
September 15, 2017: Biology Direct
https://www.readbyqxmd.com/read/28914290/reducing-routine-labs-teaching-residents-restraint
#17
Michael I Ellenbogen, Kevin J O'Leary
No abstract text is available yet for this article.
September 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28913833/symptom-trajectories-throughout-two-family-therapy-treatments-for-adolescent-anorexia-nervosa
#18
Stuart B Murray, Eva Pila, Daniel Le Grange, Susan M Sawyer, Elizabeth K Hughes
OBJECTIVE: This study aimed to examine the trajectory of symptom remission and affective functioning throughout the course of two family-based treatments for adolescent anorexia nervosa (AN): conjoint family-based treatment (FBT) and parent-focused treatment (PFT). METHOD: Participants were 107 adolescents (Mage  = 15.5 years, SD = 1.5) with a primary diagnosis of AN who participated in a randomized clinical trial comparing FBT (N = 55) and PFT (N = 51)...
September 15, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28913592/chronic-stress-causes-sex-specific-and-structure-specific-alterations-in-mitochondrial-respiratory-chain-activity-in-rat-brain
#19
Carina de Souza Mota, Simone Nardin Weis, Roberto Farina Almeida, Carla Dalmaz, Fátima Therezinha Costa Guma, Letícia Ferreira Pettenuzzo
Chronic restraint stress (CRS) induces a variety of changes in brain function, some of which are mediated by glucocorticoids. The response to stress occurs in a sex-specific way, and may include mitochondrial and synaptic alterations. The synapse is highly dependent on mitochondrial energy supply, and when mitochondria become dysfunctional, they orchestrate cell death. This study aimed to investigate the CRS effects on mitochondrial respiratory chain activity, as well as mitochondrial potential and mass in cell body and synapses using hippocampus, cortex and striatum of male and female rats...
September 14, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28913321/mixed-tumor-in-deep-lobe-and-versatility-of-acellular-dermal-matrix
#20
Jin Hwan Byun, Jung Soo Lim, Hye Kyung Lee
Frey's syndrome and infra-auricular depressed deformities are the ones of the most common complications that can occur after total parotidectomy. We report 1 case of pleomorphic adenoma occurred in the deep lobe that obtained good results from using acellular dermal matrix (ADM) after total parotidectomy. A 24-year-old man visited the hospital with oval shape mass in right mandibular angle which of 4 cm in size was found in the deep lobe of right parotid gland from Magnetic resonance imaging scanning and a pleomorphic adenoma was suspected...
June 2017: Arch Craniofac Surg
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