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"cognitive frailty"

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https://www.readbyqxmd.com/read/29644921/cognitive-frailty-and-its-association-with-all-cause-mortality-among-community-dwelling-older-adults-in-taiwan-results-from-i-lan-longitudinal-aging-study
#1
Li-Kuo Liu, Wei-Ju Lee, Yi-Hui Wu, An-Chun Hwang, Ming-Hsien Lin, Hiroyuki Shimada, Li-Ning Peng, Ching-Hui Loh, Hidenori Arai, Liang-Kung Chen
BACKGROUND: The definition of cognitive frailty and its prediction for adverse outcome of community-living older adults remains controversial. This study aims to evaluate the association between cognitive frailty and all-cause mortality among community-living older adults. METHODS: Data of the I-Lan Longitudinal Aging Study (ILAS) were retrieved for study. Frailty was defined by Fried's criteria, and a series of neuropsychological assessments, including the Mini-Mental State Examination (MMSE), Center for Epidemiology Studies-Depression (CES-D), the delay free recall in the Chinese Version Verbal Learning Test, the Boston Naming Test, the category (animal) Verbal Fluency Test, the Taylor Complex Figure Test, the digital backward and the Clock Drawing Test were performed...
April 12, 2018: Rejuvenation Research
https://www.readbyqxmd.com/read/29628032/-clinical-assessment-and-diagnostic-tools
#2
Pedro Gil Gregorio
The presence of cognitive impairment generates important changes in both affected individuals and their families and the health staff who must provide adequate care. Early identification of this alteration allows appropriate diagnosis and treatment and psychosocial and educational support, as well as the possibility of establishing care, life and financial plans. The interest of the scientific community in age-related cognitive alterations is demonstrated by the abundance of criteria and classifications. Obviously, there is a need to unify these criteria and implement longitudinal studies in order to reach reliable conclusions...
June 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/29616708/strong-relationship-between-malnutrition-and-cognitive-frailty-in-the-singapore-longitudinal-ageing-studies-slas-1-and-slas-2
#3
L Chye, K Wei, M S Z Nyunt, Q Gao, S L Wee, T P Ng
BACKGROUND: Physical frailty is well known to be strongly associated with malnutrition, but the combined impact of physical frailty and cognitive impairment among non-demented older persons (cognitive frailty) on malnutrition prevalence is not well documented. DESIGN: Cross-sectional cohort study. SETTING AND PARTICIPANTS: Community-dwelling older Singaporeans aged ≥55y (n=5414) without dementia in the Singapore Longitudinal Ageing Study (SLAS-1 and SLAS-2)...
2018: Journal of Prevention of Alzheimer's Disease
https://www.readbyqxmd.com/read/29610035/corrigendum-to-targeting-nad-degradation-the-therapeutic-potential-of-flavonoids-for-alzheimer-s-disease-and-cognitive-frailty-pharmacol-res-128-february-2018-345-358
#4
Qingwei Ruan, Jian Ruan, Weibin Zhang, Feng Qian, Zhuowei Yu
No abstract text is available yet for this article.
March 30, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29600247/the-effects-of-combinations-of-cognitive-impairment-and-pre-frailty-on-adverse-outcomes-from-a-prospective-community-based-cohort-study-of-older-chinese-people
#5
Ruby Yu, John E Morley, Timothy Kwok, Jason Leung, Osbert Cheung, Jean Woo
Objectives: To examine how various combinations of cognitive impairment (overall performance and specific domains) and pre-frailty predict risks of adverse outcomes; and to determine whether cognitive frailty may be defined as the combination of cognitive impairment and the presence of pre-frailty. Design: Community-based cohort study. Participants: Chinese men and women ( n  = 3,491) aged 65+ without dementia, Parkinson's disease and/or frailty at baseline...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29562543/different-cognitive-frailty-models-and-health-and-cognitive-related-outcomes-in-older-age-from-epidemiology-to-prevention
#6
Francesco Panza, Madia Lozupone, Vincenzo Solfrizzi, Rodolfo Sardone, Vittorio Dibello, Luca Di Lena, Francesca D'Urso, Roberta Stallone, Massimo Petruzzi, Gianluigi Giannelli, Nicola Quaranta, Antonello Bellomo, Antonio Greco, Antonio Daniele, Davide Seripa, Giancarlo Logroscino
Frailty, a critical intermediate status of the aging process that is at increased risk for negative health-related events, includes physical, cognitive, and psychosocial domains or phenotypes. Cognitive frailty is a condition recently defined by operationalized criteria describing coexisting physical frailty and mild cognitive impairment (MCI), with two proposed subtypes: potentially reversible cognitive frailty (physical frailty/MCI) and reversible cognitive frailty (physical frailty/pre-MCI subjective cognitive decline)...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29558436/motor-planning-error-toward-measuring-cognitive-frailty-in-older-adults-using-wearables
#7
He Zhou, Hyoki Lee, Jessica Lee, Michael Schwenk, Bijan Najafi
Practical tools which can be quickly administered are needed for measuring subtle changes in cognitive-motor performance over time. Frailty together with cognitive impairment, or 'cognitive frailty', are shown to be strong and independent predictors of cognitive decline over time. We have developed an interactive instrumented trail-making task (iTMT) platform, which allows quantification of motor planning error (MPE) through a series of ankle reaching tasks. In this study, we examined the accuracy of MPE in identifying cognitive frailty in older adults...
March 20, 2018: Sensors
https://www.readbyqxmd.com/read/29544875/epidemiological-and-clinical-significance-of-cognitive-frailty-a-mini-review
#8
REVIEW
Taiki Sugimoto, Takashi Sakurai, Rei Ono, Ai Kimura, Naoki Saji, Shumpei Niida, Kenji Toba, Liang-Kung Chen, Hidenori Arai
Since the operational definition of "cognitive frailty" was first proposed in 2013 by the International Academy of Nutrition and Aging and the International Association of Gerontology and Geriatrics, several studies have been carried out using this cognitive frailty model. In this review, we examined the available clinical and epidemiological evidence for cognitive frailty. Despite its low prevalence (1.0-1.8%) in the community setting, cognitive frailty has been associated with a high risk of disability, poor quality of life, and death; while cognitive frailty appears to be associated with a high risk of dementia, there is no clear evidence for this association...
March 12, 2018: Ageing Research Reviews
https://www.readbyqxmd.com/read/29521666/dual-task-performance-influence-of-frailty-level-of-physical-activity-and-cognition
#9
Paulo Giusti Rossi, Larissa Pires de Andrade, Juliana Hotta Ansai, Ana Claudia Silva Farche, Leticia Carnaz, Daniela Dalpubel, Eduardo Ferriolli, Francisco Assis Carvalho Vale, Anielle Cristhine de Medeiros Takahashi
BACKGROUND AND PURPOSE: Cognition and level of physical activity have been associated with frailty syndrome. The development of tools that assess deficits related to physical and cognitive frailties simultaneously are of common interest. However, little is known about how much these aspects influence the performance of dual-task tests. Our aims were (a) to verify the influence of frailty syndrome and objectively measured physical activity and cognition on the Timed Up and Go (TUG) test and Timed Up and Go associated with dual-task (TUG-DT) performances; and (b) to compare TUG and TUG-DT performances between older adults who develop frailty syndrome...
March 8, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29412444/frailty-and-neurodegenerative-disease-anticipating-the-future-expanding-the-framework
#10
D M Lyreskog
An array of technologies for preventing and treating age-related neural decline and disease are currently under development. A clear framework for how to identify groups in need of such inventions is needed. An encompassing concept of frailty could provide a solid basis for such purposes. Concepts of frailty, including physical and cognitive frailty, are currently applied in clinical settings, and in research and development. The terminology facilitates identifying processes of age-related physical and cognitive decline...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29408342/increasing-use-of-cognitive-measures-in-the-operational-definition-of-frailty-a-systematic-review
#11
REVIEW
R Vella Azzopardi, I Beyer, S Vermeiren, M Petrovic, N Van Den Noortgate, I Bautmans, E Gorus
Ageing is associated both with frailty and cognitive decline. The quest for a unifying approach has led to a new concept: cognitive frailty. This systematic review explores the contribution of cognitive assessment in frailty operationalization. PubMed, Web of Knowledge and PsycINFO were searched until December 2016 using the keywords aged; frail elderly; aged, 80 and over; frailty; diagnosis; risk assessment and classification, yielding 2,863 hits. Seventy-nine articles were included, describing 94 frailty instruments...
February 2, 2018: Ageing Research Reviews
https://www.readbyqxmd.com/read/29405232/cognitive-frailty-and-incidence-of-dementia-in-older-persons
#12
H Shimada, H Makizako, K Tsutsumimoto, T Doi, S Lee, T Suzuki
BACKGROUND: Cognitive frailty may be a preventive or therapeutic target for preventing dementia and functional decline with age. OBJECTIVES: To examine the relationship between physical and cognitive frailty and the incidence of dementia in community-living older persons. DESIGN: A prospective cohort study. SETTING: General community in Japan. PARTICIPANTS: A total of 4072 persons aged ≥ 65 years...
2018: Journal of Prevention of Alzheimer's Disease
https://www.readbyqxmd.com/read/29346524/-effects-of-a-primary-care-based-multifactorial-intervention-on-physical-and-cognitive-function-in-frail-elderly-individuals-a-randomized-controlled-trial
#13
Laura Romera-Liebana, Francesc Orfila, Josep Maria Segura, Jordi Real, Maria Lluïsa Fabra, Mercedes Möller, Santiago Lancho, Anna Ramirez, Nuria Marti, Montserrat Cullell, Nuria Bastida, Dolors Martinez, Maria Giné, Patricia Cendrós, Anna Bistuer, Elena Perez, Maria Assumpta Fabregat, Gonçal Foz
Background: Detecting and managing frailty at early stages can prevent disability and other adverse outcomes. The study aim was to evaluate whether a multifactorial intervention program could modify physical and cognitive frailty parameters in elderly individuals. Methods: We conducted a multicenter, randomized, single-blind, parallel-group trial in community-living pre-frail/frail elderly individuals in Barcelona. A total of 352 patients, aged ≥65 years old with positive frailty screening, was randomized into two groups to receive a 12-week multidisciplinary intervention or usual care, with concealed allocation...
January 16, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29300416/the-association-between-bmi-and-different-frailty-domains-a-u-shaped-curve
#14
M L Rietman, D L van der A, S H van Oostrom, H S J Picavet, M E T Dollé, H van Steeg, W M M Verschuren, A M W Spijkerman
OBJECTIVES: Previous studies showed a U-shaped association between BMI and (physical) frailty. We studied the association between BMI and physical, cognitive, psychological, and social frailty. Furthermore, the overlap between and prevalence of these frailty domains was examined. DESIGN: Cross-sectional study. SETTING: The Doetinchem Cohort Study is a longitudinal population-based study starting in 1987-1991 examining men and women aged 20-59 with follow-up examinations every 5 yrs...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29165541/frailty-exists-in-younger-adults-admitted-as-surgical-emergency-leading-to-adverse-outcomes
#15
R Smart, B Carter, J McGovern, S Luckman, A Connelly, J Hewitt, T Quasim, S Moug
BACKGROUND: Frailty is prevalent in the older adult population (≥65 years of age) and results in adverse outcomes in the emergency general surgical population. OBJECTIVE: To determine whether frailty exists in the younger adult emergency surgical population (<65 years) and what influence frailty may have on patient related outcomes. DESIGN: Prospective observational cohort study. SETTING: Emergency general surgical admissions...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29146224/joint-trajectories-of-cognition-and-frailty-and-associated-burden-of-patient-reported-outcomes
#16
Zuyun Liu, Ling Han, Evelyne A Gahbauer, Heather G Allore, Thomas M Gill
OBJECTIVES: To evaluate joint trajectories of cognition and frailty and their association with the cumulative burden of patient-reported outcomes, including hospitalization, nursing home admission, and disability. DESIGN: Longitudinal study of 754 community-living persons aged 70 or older. PARTICIPANTS: 690 participants who had a baseline and at least one follow-up assessment of cognition and frailty between 1998 and 2009. MEASUREMENTS: Cognition was assessed using the Mini-Mental State Examination (MMSE)...
November 14, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29104866/cognitive-frailty-in-china-results-from-china-comprehensive-geriatric-assessment-study
#17
Lina Ma, Li Zhang, Yaxin Zhang, Yun Li, Zhe Tang, Piu Chan
Objective: Cognitive frailty (CF) refers to the co-occurrence of physical frailty (PF) and cognitive impairment in persons without dementia. We aimed to explore the prevalence and associated factors of CF in China. Method: Data were obtained from the China Comprehensive Geriatric Assessment Study. A total of 5,708 community-dwelling older adults without dementia were included. CF was assessed using the Mini-Mental State Examination for the evaluation of cognitive status and the Comprehensive Geriatric Assessment-Frailty Index for the evaluation of PF...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28843528/cognitive-frailty-far-from-clinical-and-research-adoption
#18
EDITORIAL
Marco Canevelli, Matteo Cesari
No abstract text is available yet for this article.
October 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28797589/association-between-frailty-and-cognitive-impairment-cross-sectional-data-from-toulouse-frailty-day-hospital
#19
Bertrand Fougère, Matthieu Daumas, Matthieu Lilamand, Sandrine Sourdet, Julien Delrieu, Bruno Vellas, Gabor Abellan van Kan
BACKGROUND: A consensus panel, based on epidemiologic evidence, argued that physical frailty is often associated with cognitive impairment, possibly because of common underlying pathophysiological mechanisms. The concepts of cognitive frailty and motoric cognitive risk were recently proposed in literature and may represent a prodromal stage for neurodegenerative diseases. The purpose of this study was to analyze the relationship between cognition and the components of the physical phenotype of frailty...
November 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28689645/additive-role-of-a-potentially-reversible-cognitive-frailty-model-and-inflammatory-state-on-the-risk-of-disability-the-italian-longitudinal-study-on-aging
#20
Vincenzo Solfrizzi, Emanuele Scafato, Madia Lozupone, Davide Seripa, Michele Giannini, Rodolfo Sardone, Caterina Bonfiglio, Daniela I Abbrescia, Lucia Galluzzo, Claudia Gandin, Marzia Baldereschi, Antonio Di Carlo, Domenico Inzitari, Antonio Daniele, Carlo Sabbà, Giancarlo Logroscino, Francesco Panza
OBJECTIVE: Cognitive frailty is a condition recently defined by operationalized criteria describing the simultaneous presence of physical frailty and mild cognitive impairment (MCI). Two subtypes for this clinical construct have been proposed: "potentially reversible" cognitive frailty (physical frailty plus MCI) and "reversible" cognitive frailty (physical frailty plus pre-MCI subjective cognitive decline). Here the prevalence of a potentially reversible cognitive frailty model was estimated...
November 2017: American Journal of Geriatric Psychiatry
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