keyword
https://read.qxmd.com/read/38475833/efficacy-and-safety-of-gut-microbiota-based-therapies-in-autoimmune-and-rheumatic-diseases-a-systematic-review-and-meta-analysis-of-80-randomized-controlled-trials
#21
JOURNAL ARTICLE
Liuting Zeng, Kailin Yang, Qi He, Xiaofei Zhu, Zhiyong Long, Yang Wu, Junpeng Chen, Yuwei Li, Jinsong Zeng, Ge Cui, Wang Xiang, Wensa Hao, Lingyun Sun
BACKGROUND: Previous randomized controlled trials (RCTs) suggested that gut microbiota-based therapies may be effective in treating autoimmune diseases, but a systematic summary is lacking. METHODS: Pubmed, EMbase, Sinomed, and other databases were searched for RCTs related to the treatment of autoimmune diseases with probiotics from inception to June 2022. RevMan 5.4 software was used for meta-analysis after 2 investigators independently screened literature, extracted data, and assessed the risk of bias of included studies...
March 13, 2024: BMC Medicine
https://read.qxmd.com/read/38474148/eicosapentaenoic-acid-modulates-transient-receptor-potential-v1-expression-in-specific-brain-areas-in-a-mouse-fibromyalgia-pain-model
#22
JOURNAL ARTICLE
Hsien-Yin Liao, Chia-Ming Yen, I-Han Hsiao, Hsin-Cheng Hsu, Yi-Wen Lin
Pain is an unpleasant sensory and emotional experience accompanied by tissue injury. Often, an individual's experience can be influenced by different physiological, psychological, and social factors. Fibromyalgia, one of the most difficult-to-treat types of pain, is characterized by general muscle pain accompanied by obesity, fatigue, sleep, and memory and psychological concerns. Fibromyalgia increases nociceptive sensations via central sensitization in the brain and spinal cord level. We used intermittent cold stress to create a mouse fibromyalgia pain model via a von Frey test (day 0: 3...
March 1, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38471473/complications-of-implanted-vagus-nerve-stimulation-a-systematic-review-and-meta-analysis
#23
Roshini Kalagara, Susmita Chennareddy, Emma Reford, Abhiraj D Bhimani, Daniel D Cummins, Margaret H Downes, Jenna M Tosto, Joshua B Bederson, J Mocco, David Putrino, Christopher P Kellner, Fedor Panov
INTRODUCTION: Vagus Nerve Stimulation (VNS) has emerged as a promising tool in ischemic stroke rehabilitation. However, there has been no systematic review summarizing its adverse effects, critical information for patients and providers when obtaining informed consent for this novel treatment. This systematic review and meta-analysis reports the adverse effects of VNS. METHODS: A systematic review was performed in accordance with PRISMA guidelines to identify common complications after VNS therapy...
March 12, 2024: Cerebrovascular Diseases
https://read.qxmd.com/read/38470657/whole-body-cryostimulation-a-new-adjuvant-treatment-in-central-sensitization-syndromes-an-expert-opinion
#24
JOURNAL ARTICLE
Angelo Alito, Federica Verme, Gian Paolo Mercati, Paolo Piterà, Jacopo Maria Fontana, Paolo Capodaglio
Central sensitisation is defined as a multifactorial etiopathogenetic condition involving an increase in the reactivity of nociceptive neurons and alterations in pain transmission and perception in the central nervous system. Patients may present with widespread chronic pain, fatigue, sleep disturbance, dizziness, psychological (e.g., depression, anxiety, and anger) and social impairment. Pain can be spontaneous in onset and persistence, characterised by an exaggerated response and spread beyond the site of origin, and sometimes triggered by a non-painful stimulus...
February 25, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38469002/necrotizing-pneumonia-a-skeletal-muscle-lesion-and-a-fungating-duodenal-mass-an-atypical-presentation-of-rapidly-progressing-lung-adenocarcinoma
#25
Justin Ferkin, Brooke Williams, Phillip S Moore
Lung adenocarcinoma, the predominant subtype of non-small cell lung cancer, typically metastasizes to common sites such as the liver and adrenal glands. However, rare instances involve skeletal muscle metastasis. We present a case of a 45-year-old female with a medical history of hypertension, epilepsy, and fibromyalgia, who presented to the emergency department with hemoptysis and multifocal pain. Chest imaging revealed a cavitary lesion which appeared to be necrotizing pneumonia. Further investigations uncovered a fluid collection in the left thigh, which would be identified as poorly differentiated carcinoma...
February 2024: Curēus
https://read.qxmd.com/read/38468535/the-role-of-sars-cov-2-spike-protein-in-long-term-damage-of-tissues-and-organs-the-underestimated-role-of-retrotransposons-and-stem-cells-a-working-hypothesis
#26
JOURNAL ARTICLE
Mario G Balzanelli, Reza Rastanesh, Pietro Distratis, Rita Lazzaro, Francesco Inchingolo, Raffaele Del Prete, Van H Pham, Sergey K Aityan, Toai Tran Cong, Kieu C D Nguyen, Ciro Gargiulo Isacco
Coronavirus disease-2019 (COVID-19) is a respiratory disease in which Spike protein from SARS-CoV-2 plays a key role in transferring virus genomic code into target cells. Spike protein, which is found on the surface of the SARS-CoV-2 virus, latches onto angiotensin-converting enzyme 2 receptors (ACE2r) on target cells. The RNA genome of coronaviruses, with an average length of 29 kb, is the longest among all RNA viruses and comprises six to ten open reading frames (ORFs) responsible for encoding replicase and structural proteins for the virus...
March 11, 2024: Endocrine, Metabolic & Immune Disorders Drug Targets
https://read.qxmd.com/read/38468467/prevalence-of-fibromyalgia-and-irritable-bowel-syndrome-and-its-association-with-studying-medicine-a-cross-sectional-study-in-al-baath-university-syria
#27
JOURNAL ARTICLE
Mohanad Daher, Sara Abbas, Zainab Asaad, Karam Khalil, Ghania Jadid
BACKGROUND: The aim of this study is to assess the prevalence rate of fibromyalgia (FM) and irritable bowel syndrome (IBS) among Al-Baath University students and find out whether studying medicine has an association with a higher prevalence rate. METHODS: The participants of this observational cross-sectional study were students aged 18-30 years from Al-Baath University. A structured self-estimated electronic questionnaire developed by Google Forms was distributed using social media platforms from 15 February to 15 March, 2023...
March 2024: Brain and Behavior
https://read.qxmd.com/read/38465808/-features-of-fibromyalgia-in-patients-with-rheumatoid-arthritis
#28
JOURNAL ARTICLE
N A Melikova, E G Filatova, E S Filatova
OBJECTIVE: To determine the features of fibromyalgia (FM) in patients with rheumatoid arthritis (RA). MATERIAL AND METHODS: Seventy-six patients participated in the study. The patients were divided into 2 groups: RA+FM ( n =55), FM ( n =21). Anamnesis of life and disease was carefully collected in all patients. The intensity (according to VAS) and phenotype (Pain DETECT, DN4) of pain syndrome (PS), the presence of symptoms of central sensitization (CSI), fatigue (FSS), signs of anxiety and depression (HADS), sleep quality (PSQI), cognitive functions (DSST) and quality of life (QoL) (EQ-5D, FIQR) were also evaluated...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38465077/effect-of-steroids-on-patients-with-fibromyalgia-chromic-widespread-pain-an-observational-study
#29
JOURNAL ARTICLE
Obuli Srinivasan Gurunathan, Eswaradass Chellapandian, Sibi Thirunavukkarasu, Sathvika Thermalingem, Prasanna Eswaradass
OBJECTIVE: Fibromyalgia causes widespread chronic pain. Pain management and treating underlying conditions are of utmost importance. Recent studies found an association of thyroid autoimmunity with fibromyalgia. Pain management of patients with anti-thyroid peroxidase antibody (anti-TPO Ab) positive was studied sparsely. To determine the effect of steroid (deflazacort) on pain management using numerical rating scale (NRS) pain score at baseline and at 3-month follow-up. STUDY DESIGN: A retrospective observational study was undertaken, recruiting patients diagnosed with fibromyalgia as per 2010 American College of Rheumatology guidelines and treated with the steroid, deflazacort 12 mg...
February 2024: Curēus
https://read.qxmd.com/read/38463111/the-prevalence-of-fibromyalgia-in-adults-at-al-karak-jordan-a-cross-sectional-study
#30
JOURNAL ARTICLE
Alaa Akel, Mohammed Y Sarhan, Majed Al Dwairy, Belal Al-Zu'bi, Ala Al-Qudah, Omar A Alsmarat, Taif Alsaraireh, Mohammad Abu-Jeyyab
INTRODUCTION: Fibromyalgia is a chronic and intricate musculoskeletal disorder characterized by widespread pain, fatigue, and tenderness in specific anatomical regions. Although its prevalence varies among populations, understanding the prevalence in different geographical areas is crucial for healthcare planning. This cross-sectional study aims to determine the prevalence of fibromyalgia in adults residing in Al-Karak, Jordan. The city's unique demographic and environmental characteristics may influence the occurrence of fibromyalgia among its adult population...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38458049/measurement-properties-of-the-backward-walk-test-in-people-with-balance-and-mobility-deficits-a-systematic-review
#31
REVIEW
Jie Hao, Yuqi Pu, Zhengting He, Andréas Remis, Zixuan Yao, Yanfei Li
BACKGROUND: Backward walking is an indispensable component of activities of daily living. The backward walk test has been used to assess balance, mobility, and fall risk in different populations. This systematic review aimed to identify and synthesize measurement properties of the backward walk test in people with balance and mobility deficits. METHODS: Three bibliographic databases, PubMed, Embase, and Scopus, were searched on June 18th, 2023. Cross-sectional or cohort studies assessing the measurement properties (reliability, validity, responsiveness) of the backward walk test were included...
March 2, 2024: Gait & Posture
https://read.qxmd.com/read/38456638/acute-compartment-syndrome-and-rhabdomyolysis-caused-by-a-single-electrical-muscle-stimulation-in-a-46-year-old-female-professional-athlete-with-fibromyalgia-chronic-fatigue-syndrome-and-myofascial-disorder-a-case-report
#32
JOURNAL ARTICLE
Karen M von Deneen, Dereje Gobena Alemayehu, Ajit Khosla
Electrical muscle stimulation (EMS) training has been recognized as an effective modality for improving body composition, enhancing body strength, and facilitating injury recovery. However, individuals who are new to EMS training and those with certain chronic diseases should exercise caution due to the increased risk of rhabdomyolysis. This case report describes the occurrence of rhabdomyolysis and gluteal compartment syndrome following a single session of EMS training in a 46-year-old Caucasian female professional athlete...
March 5, 2024: Clinical Journal of Sport Medicine
https://read.qxmd.com/read/38451142/neuromodulation-with-aerobic-exercise-reduces-fatigue-in-systemic-lupus-erythematosus-a-randomised-sham-controlled-double-blind-study
#33
JOURNAL ARTICLE
Vanessa P de Andrade, Alexandre M Dos Santos, Luciana P C Seguro, Emily F N Yuki, Michelle R U Lopes, Marcus V Grecco, Eduardo F Borba, Julia M A Greve, Samuel K Shinjo
OBJECTIVES: Transcranial direct current stimulation (tDCS) combined with aerobic exercise (tDCS-AE) effectively reduces fatigue in patients with fibromyalgia. However, no study has assessed this method in systemic lupus erythematosus (SLE) patients with significant fatigue. Therefore, we evaluated the safety and efficacy of tDCS-AE for significant fatigue symptoms in adult female SLE patients. METHODS: This randomised, sham-controlled, double-blind study included 25 patients with SLE in remission or low disease activity (SLEDAI-2K £4) and with significant fatigue [≥36 points on the Fatigue Severity Scale (FSS) or ≥38 points on the Modified Fatigue Scale (MFIS)]...
March 7, 2024: Clinical and Experimental Rheumatology
https://read.qxmd.com/read/38450074/evaluating-the-efficacy-and-acceptability-of-vagus-nerve-stimulation-for-fibromyalgia-a-prisma-compliant-protocol-for-a-systematic-review-and-meta-analysis
#34
JOURNAL ARTICLE
Yunhuo Cai, Yajun Zhang, Yiyan Fang, Hantong Hu, Xingling Li, Lianqiang Fang
BACKGROUND: Fibromyalgia has imposed substantial burdens on patients' health and well-being, yet effective therapeutic options for this condition remain limited. Recently, vagus nerve stimulation (VNS) has emerged as a promising therapy for fibromyalgia. Nonetheless, despite the increasing number of randomized clinical trials (RCTs), current evidence remains inconclusive. Therefore, this protocol of a systematic review and meta-analysis aims to synthesize the existing evidence to clarify the efficacy and acceptability of VNS for treating fibromyalgia...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38447702/measurement-of-event-related-potentials-from-electroencephalography-to-evaluate-emotional-processing-in-fibromyalgia-syndrome-a-systematic-review-and-meta-analysis
#35
REVIEW
L R Fischer-Jbali, A Alacreu, C M Galvez-Sánchez, C I Montoro
OBJECTIVE: The present systematic review and meta-analysis intended to: 1) determine the extent of abnormalities in emotional processing linked to emotional event-related potentials (ERPs) in Fibromyalgia Syndrome (FMS) and 2) integrate data from similar emotional tasks into a meta-analysis to clearly demonstrate the scientific and clinical value of measuring emotional ERPs by electroencephalography (EEG) in FMS. METHODS: A systematic review and meta-analysis of studies comparing emotional processing indicated by ERPs in FMS patients and controls was conducted...
March 4, 2024: International Journal of Psychophysiology
https://read.qxmd.com/read/38447497/efficacy-of-aquatic-vs-land-based-therapy-for-pain-management-in-women-with-fibromyalgia-a-randomised-controlled-trial
#36
JOURNAL ARTICLE
S Rivas Neira, A Pasqual Marques, R Fernández Cervantes, M T Seoane Pillado, J Vivas Costa
OBJECTIVE: To determine the efficacy of two physiotherapeutic interventions - aquatic therapy (AT) and land-based therapy (LBT) - for reducing pain in women with fibromyalgia. DESIGN: Single-blind, randomised controlled, equivalence trial. SETTING: Fibromyalgia, Chronic Fatigue Syndrome and Multiple Chemical Sensitivity Association in A Coruña, Spain. PARTICIPANTS: Forty women with fibromyalgia were assigned at random in a 1:1 manner to two groups: AT (n = 20) and LBT (n = 20)...
February 17, 2024: Physiotherapy
https://read.qxmd.com/read/38445639/dealing-with-fibromyalgia-in-the-family-context-a-qualitative-description-study
#37
JOURNAL ARTICLE
Luz de Myotanh Vázquez Canales, Inmaculada Pereiró Berenguer, Eduardo Aguilar García-Iturrospe, Charo Rodríguez
Headings purpose: Fibromyalgia (FM) is a chronic, nondegenerative disease with important limitations in patients. Its average global prevalence is 1.78%, and women are more affected than men (3:1). Due to the lack of objective diagnostic tools, it is a complex medical condition that is frequently unseen by patients' relatives and doctors, which might nonetheless have a noticeable impact on the patient's entourage. Material and Methods: This qualitative descriptive study aimed to elicit family members' views on how FM affects their lives...
March 6, 2024: Scandinavian Journal of Primary Health Care
https://read.qxmd.com/read/38443140/power-doppler-signal-at-the-enthesis-and-bone-erosions-are-the-most-discriminative-omeract-ultrasound-lesions-for-spa-results-from-the-deus-defining-enthesitis-on-ultrasound-in-spondyloarthritis-multicentre-study
#38
JOURNAL ARTICLE
Andrea Di Matteo, Gianluca Smerilli, Stefano Di Donato, An Ran Liu, Andrea Becciolini, Federica Camarda, Tomas Cazenave, Edoardo Cipolletta, Davide Corradini, Juan José de Agustín, Giulia Maria Destro Castaniti, Eleonora Di Donato, Luca Di Geso, Emine Duran, Bayram Farisogullari, Marco Fornaro, Francesca Francioso, Pamela Giorgis, Amelia Granel, Cristina Hernández-Díaz, Rudolf Horvath, Jana Hurnakova, Diogo Jesus, Omer Karadag, Ling Li, Josefina Marin, María Victoria Martire, Xabier Michelena, Erica Moscioni, Laura Muntean, Matteo Piga, Marcos Rosemffet, João Rovisco, Didem Sahin, Fausto Salaffi, Liliana Saraiva, Crescenzio Scioscia, Maria-Magdalena Tamas, Shun Tanimura, Aliki Venetsanopoulou, Lucio Ventura-Rios, Orlando Villota, Catalina Villota-Eraso, Paraskevi V Voulgari, Gentiana Vukatana, Johana Zacariaz Hereter, Helena Marzo-Ortega, Walter Grassi, Emilio Filippucci
OBJECTIVES: To assess, in spondyloarthritis (SpA), the discriminative value of the Outcome Measures in Rheumatology (OMERACT) ultrasound lesions of enthesitis and their associations with clinical features in this population. METHODS: In this multicentre study involving 20 rheumatology centres, clinical and ultrasound examinations of the lower limb large entheses were performed in 413 patients with SpA (axial SpA and psoriatic arthritis) and 282 disease controls (osteoarthritis and fibromyalgia)...
March 5, 2024: Annals of the Rheumatic Diseases
https://read.qxmd.com/read/38440910/continuum-of-somatosensory-profiles-in-breast-cancer-survivors-with-and-without-pain-compared-to-healthy-controls-and-patients-with-fibromyalgia
#39
JOURNAL ARTICLE
Vincent Haenen, Lore Dams, Mira Meeus, Nele Devoogdt, Bart Morlion, Amber De Groote, An De Groef
CONTEXT: The prevalence of persistent pain among breast cancer survivors (BCS) is high, and it is unclear what distinguishes those with persistent pain from those without. Research suggests that differences in somatosensory function evaluated by quantitative sensory testing (QST) may be responsible. OBJECTIVES: This study aimed to describe somatosensory profiles in terms of hyper- and hypoesthesia in BCS with and without persistent pain using reference data from healthy controls...
March 5, 2024: European Journal of Pain: EJP
https://read.qxmd.com/read/38434480/brain-heart-interactions-in-fibromyalgia-syndrome
#40
JOURNAL ARTICLE
Valton Costa, Anna Carolyna Gianlorenço, Kevin Pacheco-Barrios, Felipe Fregni
No abstract text is available yet for this article.
February 16, 2024: Principles and practice of clinical research
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