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"Fibromyalgia"

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https://www.readbyqxmd.com/read/29149921/gastrointestinal-and-hepatic-disease-in-fibromyalgia
#1
REVIEW
Richard A Schatz, Baharak Moshiree
Fibromyalgia (FM) has historically been associated with several diseases in gastroenterology and hepatology. The most substantiated evidence pertains to irritable bowel syndrome (IBS). The pathogeneses of FM and IBS remain unclear, but it is likely related to dysregulation within the brain-gut axis, resulting in a hyperalgesic state. IBS and FM share other similarities, including a female predominance, fatigue, insomnia, and susceptibility to psychiatric state. These common manifestations and pathogeneses serve as a foundation for overlapping, multidisciplinary treatment modalities...
February 2018: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/29149437/a-blinded-randomized-placebo-controlled-study-to-investigate-the-efficacy-and-safety-of-ferric-carboxymaltose-in-iron-deficient-patients-with-fibromyalgia
#2
Chad S Boomershine, Todd A Koch, David Morris
INTRODUCTION: This study sought to compare efficacy and safety of ferric carboxymaltose vs. placebo in iron-deficient patients with fibromyalgia. METHODS: This blinded, placebo-controlled, phase 2 study randomized adults with fibromyalgia and Revised Fibromyalgia Impact Questionnaire (FIQR) scores ≥ 60, ferritin levels < 0.05 µg/ml, and transferrin saturation < 20% (1:1) to receive ferric carboxymaltose [15 mg/kg (up to 750 mg)], or placebo (15 cc normal saline) intravenously on study days 0 and 5...
November 17, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/29135602/ocular-surface-alterations-in-the-context-of-corneal-in-vivo-confocal-microscopic-characteristics-in-patients-with-fibromyalgia
#3
Kadriye Erkan Turan, Sibel Kocabeyoglu, Isin Unal-Cevik, Figen Bezci, Aysen Akinci, Murat Irkec
PURPOSE: To quantify the morphology of corneal basal epithelium and subbasal nerves and to evaluate the ocular surface alterations in patients with fibromyalgia (FM). METHODS: Patients with FM (n = 34) and healthy controls (n = 42) were enrolled. All participants underwent ocular surface tests in the following order: corneal sensitivity, tear film breakup time, lissamine green staining, Schirmer test, and the Ocular Surface Disease Index questionnaire. Basal epithelial cells and subbasal nerves were evaluated using in vivo confocal microscopy (IVCM)...
November 9, 2017: Cornea
https://www.readbyqxmd.com/read/29133662/a-tiny-tick-can-cause-a-big-health-problem
#4
Manuel John, M Raman, Keith Ryan
Ticks are tiny crawling bugs in the spider family that feed by sucking blood from animals. They are second only to mosquitoes as vectors of human disease, both infectious and toxic. Infected ticks spread over a hundred diseases, some of which are fatal if undetected. They spread the spirochete (which multiplies in the insect's gut) with a subsequent bite to the next host. We describe the only reported cases of peri ocular tick bite from India that presented to us within a span of 3 days and its management. Due suspicion and magnification of the lesions revealed the ticks which otherwise masqueraded as small skin tags/moles on gross examination...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29130724/probiotics-for-fibromyalgia-study-design-for-a-pilot-double-blind-randomized-controlled-trial
#5
Pablo Roman, Ángeles F Estévez, Nuria Sánchez-Labraca, Fernando Cañadas, Alonso Miras, Diana Cardona
BACKGROUND: Fibromyalgia syndrome (FMS) is a chronic, generalized and diffuse pain disorder accompanied by other symptoms such as emotional and cognitive deficits. The FMS patients show a high prevalence of gastrointestinal symptoms. Recently it has been found that microbes in the gut may regulate brain processes through the gut-microbiota-brain axis, modulating thus affection, motivation and higher cognitive functions. Therefore, the use of probiotics might be a new treatment that could improve the physical, psychological and cognitive state in FMS; however, no evidence about this issue is available...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29127814/alexithymia-not-fibromyalgia-predicts-the-attribution-of-pain-to-anger-related-facial-expressions
#6
Marialaura Di Tella, Ivan Enrici, Lorys Castelli, Fabrizio Colonna, Enrico Fusaro, Ada Ghiggia, Annunziata Romeo, Valentina Tesio, Mauro Adenzato
BACKGROUND: Fibromyalgia (FM) is a syndrome characterized by chronic, widespread musculoskeletal pain, occurring predominantly in women. Previous studies have shown that patients with FM display a pattern of selective processing or cognitive bias which fosters the encoding of pain-related information. The present study tested the hypothesis of an increased attribution of pain to facial expressions of emotions (FEE), in patients with FM. As previous studies have shown that alexithymia influences the processing of facial expressions, independent of specific clinical conditions, we also investigated whether alexithymia, rather than FM per se, influenced attribution of pain to FEE...
November 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29123619/vitamin-d-and-fibromyalgia-a-meta-analysis
#7
REVIEW
Atekeh Hadinezhad Makrani, Mahdi Afshari, Marayam Ghajar, Zahra Forooghi, Mahmood Moosazadeh
Vitamin D is a cofactor responsible for autoimmune disorders. There is no agreement in the studies investigating the association between vitamin D and fibromyalgia. This study aims to combine the conflicting results of the primary studies which compared these patients with control groups regarding the serum concentration of vitamin D. This meta-analysis has been designed based on PRISMA guidelines. Relevant keywords were searched in PubMed, Science direct, Scopus, Cochrane, and Google scholar and primary studies were selected...
October 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/29115388/antinociceptive-effect-of-valeriana-fauriei-regulates-bdnf-signaling-in-an-animal-model-of-fibromyalgia
#8
Hwayoung Lee, Jiyun Im, Hansol Won, Jun Young Kim, Hyung-Ki Kim, Jun-Tack Kwon, Young Ock Kim, Sanghyun Lee, Ik-Hyun Cho, Sang Won Lee, Hak-Jae Kim
The genus Valeriana has been widely used in popular medicine for centuries, to treat sleep disorders, anxiety, epilepsy and insomnia. Recent studies have focused on the novel pharmacological effects of Valeriana fauriei Briq. (VF) species. Previous studies have attempted to determine the pharmacological functions of Valeriana in various human diseases, particularly with regards to its neuroprotective effects, and its ability to reduce pain and stress. The present study constructed an animal model of fibromyalgia (FM), which was induced by intermittent cold stress with slight modification...
October 20, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29112660/opioid-prescribing-patterns-patient-use-and-postoperative-pain-after-hysterectomy-for-benign-indications
#9
Sawsan As-Sanie, Sara R Till, Erika L Mowers, Courtney S Lim, Bethany D Skinner, Laura Fritsch, Alex Tsodikov, Vanessa K Dalton, Daniel J Clauw, Chad M Brummett
OBJECTIVE: To quantify physician prescribing patterns and patient opioid use in the 2 weeks after hysterectomy at an academic institution and to determine whether patient factors predict postsurgical opioid use and pain recovery. METHODS: We conducted a prospective quality initiative study by recruiting all English-speaking patients undergoing hysterectomy for benign, nonobstetric indications at a university hospital between August 2015 and December 2015, excluding those with major medical morbidities or substance abuse...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29110306/coping-strategies-and-perceived-social-support-in-fibromyalgia-syndrome-relationship-with-alexithymia
#10
Marialaura Di Tella, Valentina Tesio, Ada Ghiggia, Annunziata Romeo, Fabrizio Colonna, Enrico Fusaro, Giuliano Carlo Geminiani, Maria Bruzzone, Riccardo Torta, Lorys Castelli
Fibromyalgia (FM) is a chronic pain syndrome characterized by high levels of psychological distress and alexithymia, a personality disposition affecting emotional self-awareness. The main aim of the present study was to investigate for the first time the relationship between alexithymia and coping strategies on the one hand, and alexithymia and perceived social support on the other, in a sample of FM patients. To reach this aim, 153 FM patients completed a battery of tests assessing coping strategies, perceived social support, alexithymia, psychological distress and pain intensity...
November 7, 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/29109601/treatment-of-fibromyalgia
#11
REVIEW
Richard Kwiatek
No abstract text is available yet for this article.
October 2017: Australian Prescriber
https://www.readbyqxmd.com/read/29108831/are-the-acr-2010-diagnostic-criteria-for-fibromyalgia-better-than-the-1990-criteria
#12
REVIEW
Piercarlo Sarzi-Puttini, Fabiola Atzeni, Ignazio Francesco Masala, Fausto Salaffi, Joab Chapman, Ernest Choy
Fibromyalgia (FM) is difficult to diagnose and manage chronic pain condition whose symptoms have no clear pathophysiological cause, although it is thought that patient hypersensitivity to a range of stimuli may give rise to mechanical hyperalgesia as a result of altered central nociceptive processing. The 1990 American College of Rheumatology (ACR) classification criteria, which have been widely used in clinical practice, require the existence of chronic widespread pain (CWP) for >3months, and the presence of at least 11 out of 18 specified tender points upon digital palpation, although this latter criterion has long been criticised...
November 3, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29108826/physical-activity-and-autoimmune-diseases-get-moving-and-manage-the-disease
#13
REVIEW
Kassem Sharif, Abdulla Watad, Nicola Luigi Bragazzi, Micheal Lichtbroun, Howard Amital, Yehuda Shoenfeld
Physical activity, by definition, is any skeletal muscle body movement that results in energy expenditure. In the last few decades, a plethora of scientific evidences have accumulated and confirmed the beneficial role of physical activity as a modifiable risk factor for a wide variety of chronic diseases including cardiovascular diseases (CVDs), diabetes mellitus and cancer, among others. Autoimmune diseases are a heterogeneous group of chronic diseases, which occur secondary to loss of self-antigen tolerance...
November 3, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29102507/occurrence-of-chronic-pelvic-pain-abnormal-uterine-bleeding-and-hysterectomy-post-procedure-among-women-who-have-undergone-female-sterilization-procedures-a-retrospective-claims-analysis-of-commercially-insured-women-in-the-us
#14
Patricia I Carney, Jianying Yao, Jay Lin, Amy Law
STUDY OBJECTIVE: To evaluate the frequency of chronic pelvic pain (CPP), abnormal uterine bleeding (AUB), and hysterectomy following hysteroscopic (HS) and laparoscopic (LS) sterilization in the US DESIGN: Retrospective cohort study (Canadian Task Force II-2) SETTING: Commercially-insured women PATIENTS: Women (18-49) with claims for HS or LS (1/1/2010-12/31/2012) were identified from the MarketScan Commercial database. Women were required to have 6 months of continuous coverage prior to (baseline) and 24 months after (follow-up) the procedure date...
November 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29099955/screening-for-adult-adhd-in-patients-with-fibromyalgia-syndrome
#15
Roland van Rensburg, Helgard Pieter Meyer, Sonia Anne Hitchcock, Christian Edward Schuler
Objective: Fibromyalgia syndrome (FMS) is a common chronic pain disorder associated with altered activity of neurotransmitters involved in pain sensitivity such as dopamine, serotonin, and noradrenaline. FMS may significantly impact an individual's functioning due to the presence of chronic pain, fatigue, and cognitive impairment. Dyscognition may be more disabling than the chronic pain but is mostly under-recognized. This study aimed to assess the potential co-occurrence of FMS and adult attention deficit hyperactivity disorder (ADHD), a chronic neurodevelopmental disorder also associated with impaired cognition and dopaminergic function...
November 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29093972/pain-processing-and-vegetative-dysfunction-in-fibromyalgia-a-study-by-sympathetic-skin-response-and-laser-evoked-potentials
#16
Marina de Tommaso, Katia Ricci, Giuseppe Libro, Eleonora Vecchio, Marianna Delussi, Anna Montemurno, Giuseppe Lopalco, Florenzo Iannone
Background: A dysfunction of pain processing at central and peripheral levels was reported in fibromyalgia (FM). We aimed to correlate laser evoked potentials (LEPs), Sympathetic Skin Response (SSR), and clinical features in FM patients. Methods: Fifty FM patients and 30 age-matched controls underwent LEPs and SSR by the right hand and foot. The clinical evaluation included FM disability (FIQ) and severity scores (WPI), anxiety (SAS) and depression (SDS) scales, and questionnaires for neuropathic pain (DN4)...
2017: Pain Research and Treatment
https://www.readbyqxmd.com/read/29093080/adherence-and-persistence-with-drug-therapy-among-fibromyalgia-patients-data-from-a-large-health-maintenance-organization
#17
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29080932/treatment-of-drug-resistant-fibromyalgia-symptoms-using-high-intensity-laser-therapy-a-case-based-review
#18
REVIEW
Paul F White, Jason Zafereo, Ofelia Loani Elvir-Lazo, Hector Hernandez
Fibromyalgia is a chronic musculoskeletal condition characterized by widespread pain in the body and is associated with tender points at the shoulder, back and hip regions. A wide variety of pharmacologic drugs and dietary supplements have been used with limited success in treating the musculoskeletal pain. Early clinical studies with low level laser therapy (LLLT) alone or in combination with drugs commonly used to treat fibromyalgia suggested that LLLT may be effective in reducing musculoskeletal pain and stiffness, as well as the number of tender locations...
October 28, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29080671/sex-differences-and-estradiol-involvement-in-hyperalgesia-and-allodynia-in-an-experimental-model-of-fibromyalgia
#19
Alberto Hernandez-Leon, Yarim Elideth De la Luz-Cuellar, Vinicio Granados-Soto, María Eva González-Trujano, Alonso Fernández-Guasti
Fibromyalgia (FM) is a musculoskeletal chronic pain syndrome. Its prevalence in women is higher than in men possibly by hormonal factors given that symptoms are aggravated during sex hormone-related events, such as the premenstrual period, pregnancy, postpartum or menopause. The aim of the present study was to investigate whether hyperalgesia and allodynia, in reserpine-induced experimental FM, depend on sex, estrous cycle, ovariectomy and replacement with 17β-estradiol. To fulfill this objective, we compared males, intact females with known estrous cycle phases and ovariectomized (OVX) rats treated with 17β-estradiol...
November 8, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29080228/morphology-of-subcortical-brain-nuclei-is-associated-with-autonomic-function-in-healthy-humans
#20
James K Ruffle, Steven J Coen, Vincent Giampietro, Steven C R Williams, A Vania Apkarian, Adam D Farmer, Qasim Aziz
The autonomic nervous system (ANS) is a brain body interface which serves to maintain homeostasis by influencing a plethora of physiological processes, including metabolism, cardiorespiratory regulation and nociception. Accumulating evidence suggests that ANS function is disturbed in numerous prevalent clinical disorders, including irritable bowel syndrome and fibromyalgia. While the brain is a central hub for regulating autonomic function, the association between resting autonomic activity and subcortical morphology has not been comprehensively studied and thus was our aim...
October 28, 2017: Human Brain Mapping
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