John T Martin, Andrew H Milby, Kensuke Ikuta, Subash Poudel, Christian G Pfeifer, Dawn M Elliott, Harvey E Smith, Robert L Mauck
UNLABELLED: Tissue engineering strategies have emerged in response to the growing prevalence of chronic musculoskeletal conditions, with many of these regenerative methods currently being evaluated in translational animal models. Engineered replacements for fibrous tissues such as the meniscus, annulus fibrosus, tendons, and ligaments are subjected to challenging physiologic loads, and are difficult to track in vivo using standard techniques. The diagnosis and treatment of musculoskeletal conditions depends heavily on radiographic assessment, and a number of currently available implants utilize radiopaque markers to facilitate in vivo imaging...
October 2015: Acta Biomaterialia