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https://www.readbyqxmd.com/read/29145580/effect-of-botulinum-toxin-a-on-muscle-healing-and-its-implications-in-aesthetic-and-reconstructive-surgery
#1
Eldad Silberstein, Ehud Maor, Oleg Sukmanov, Alexander Bogdanov Berezovsky, Yaron Shoham, Yuval Krieger
Background: Muscle activity contributes to the enhancement of facial aging deformity, blepharospasm, cerebral palsy spasticity, trismus, torticollis, and other conditions. Myotomy of the involved muscles in order to reduce the deformity has variable success rates due to muscle healing and regeneration of activity. Objectives: The goal of this study was to investigate whether blocking striated muscle activity with Botulinum toxin (BtxA) during the healing time after myotomy alters the healing process and reduces long-term muscle activity...
November 14, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29145526/factors-affecting-the-decision-to-use-cemented-or-screw-retained-fixed-implant-supported-prostheses-a-critical-review
#2
Miguel Gómez-Polo, Rocio Ortega, Cristina Gómez-Polo, Alicia Celemin, Jaime Del Rio Highsmith
PURPOSE: This review aimed to compile and enumerate all the factors described in the literature that may affect the decision to use either cemented or screw-retained restorations and to determine the relative weights of each factor by type of retention and prosthesis. MATERIALS AND METHODS: The literature was reviewed, and the factors were classified as either determining (present in a clinical situation in which one of the retention mechanisms was clearly more suitable than the other) or conditioning (present in clinical situations in which one type of restoration was not clearly more advantageous than the other)...
November 16, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29145111/a-novel-protein-tyrosine-phosphatase-like-phytase-from-lactobacillus-fermentum-nkn51-cloning-characterization-and-application-in-mineral-release-for-food-technology-applications
#3
Rekha Sharma, Piyush Kumar, Vandana Kaushal, Rahul Das, Naveen Kumar Navani
A novel protein tyrosine phosphatase like phytase (PTPLP), designated as PhyLf from probiotic bacterium Lactobacillus fermentum NKN51 was identified, cloned, expressed and characterized. The recombinant PhyLf showed specific activity of 174.5 U/mg. PhyLf exhibited strict specificity towards phytate and optimum temperature at 60 °C, pH 5.0 and ionic strength of 100 mM. Km and Kcat of PhyLf for phytate were 0.773 mM and 84.31 s(-1), respectively. PhyLf exhibited high resistance against oxidative inactivation...
November 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29145002/different-transport-behaviors-of-bacillus-subtilis-cells-and-spores-in-saturated-porous-media-implications-for-contamination-risks-associated-with-bacterial-sporulation-in-aquifer
#4
Qi Li, Jiakuan Yang, Wei Fan, Dandan Zhou, Xiaoyu Wang, Leilei Zhang, Mingxin Huo, John C Crittenden
In this study, we compared the transport characteristics of Bacillus subtilis cells and their spores in saturated porous media. Both the bacteria cells and spores were readily transported under lower ionic strengths (IS) (1mM), featuring high mass recovery rates (>75%). The bacteria cells recovery rate declined to 58.05% when the IS increased to 100mM; but the spores recovery rate remained at 74.54%. Spores appear to be more mobile than bacterial cells over wide range of IS. Surface properties and breakthrough curves analysis of the two bio-particles (cells and spores) indicated that attachment, straining and blocking mechanisms contribute differently to deposition processes...
November 11, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29144877/role-of-proteolytic-enzyme-inhibitors-on-carious-and-eroded-dentin-associated-with-a-universal-bonding-system
#5
M C Giacomini, Pmc Scaffa, L P Chaves, Cmp Vidal, T N Machado, H M Honório, L Tjäderhane, L Wang
OBJECTIVES: The aim of this study was to evaluate the effect of proteolytic inhibitors on the bond strength of a universal adhesive system (etch-and-rinse mode) applied to artificial carious and eroded dentin. METHODS: Ninety molars were prepared and randomly divided into three groups according to the substrate: N, no challenges; ACD, artificial carious dentin simulation and ERO, artificial erosion simulation with orange juice. All groups were redivided into three subgroups according to the dentin pretreatment: W, water; CHX, 2% digluconate chlorhexidine; and E-64 (trans-epoxysuccinyl-L-leucylamido-[4-guanidino] butane), 5 μM E-64 inhibitor...
November 2017: Operative Dentistry
https://www.readbyqxmd.com/read/29144757/versatile-encapsulation-technology-based-on-tailored-ph-responsive-amphiphilic-polymers-emulsion-gels-and-capsules
#6
Clémentine Locatelli-Champagne, Jean-Marc Suau, Olivier Guerret, Charlotte Pellet, Michel Cloitre
We present a multipurpose technology to encapsulate hydrophobic substances in micron-size emulsion droplets and capsules. The encapsulating agent is a comb-like stimuli-responsive copolymer comprising side chain surfactants attached to a methacrylic acid/ethylacrylate polyelectrolyte backbone. The composition and structure of the hydrophobic moieties of the side chains are customized in order to tune the particle morphology and the processing conditions. The technology exploits the synergy of properties provided by the copolymer: interfacial activity, pH responsiveness, and viscoelasticity...
November 16, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29143443/multiscale-characterisation-of-cortical-bone-composition-microstructure-and-nanomechanical-properties-in-experimentally-induced-osteoporosis
#7
Furqan A Shah, Adrian Stoica, Carina Cardemil, Anders Palmquist
Cortical bone plays a vital role in determining overall bone strength. We investigate the structural, compositional, and nanomechanical properties of cortical bone following ovariectomy (OVX) of 12 week old Sprague Dawley rats, since this animal model is frequently employed to evaluate the performance of implantable biomaterials in compromised bone healing conditions. Morphological parameters and material properties of bone in the geometrical centre of the femoral cortex were investigated four and eight weeks post-OVX and in unoperated controls (Ctrl), using X-ray micro-computed tomography, backscattered electron scanning electron microscopy, Raman spectroscopy, and nanoindentation...
November 16, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29143352/assessment-of-exposure-to-radio-frequency-electromagnetic-fields-from-smart-utility-meters-in-gb-part-ii-numerical-assessment-of-induced-sar-within-the-human-body
#8
Muhammad R A Qureshi, Yasir Alfadhl, Xiaodong Chen, Azadeh Peyman, Myron Maslanyj, Simon Mann
Human body exposure to radiofrequency electromagnetic waves emitted from smart meters was assessed using various exposure configurations. Specific energy absorption rate distributions were determined using three anatomically realistic human models. Each model was assigned with age- and frequency-dependent dielectric properties representing a collection of age groups. Generalized exposure conditions involving standing and sleeping postures were assessed for a home area network operating at 868 and 2,450 MHz...
November 16, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/29143267/hamstring-injury-prevention-practices-in-elite-sport-evidence-for-eccentric-strength-vs-lumbo-pelvic-training
#9
REVIEW
Anthony J Shield, Matthew N Bourne
Hamstring strain injuries are endemic in running-based sports. Given the economic and performance implications of these injuries, a significant body of research has emerged in recent years in an attempt to identify risk factors and develop or optimise injury prevention strategies. Surveys of injury prevention practices among medical and conditioning staff in elite sport suggest that many sporting clubs invest significant efforts in eccentric hamstring conditioning and lumbo-pelvic or trunk stability programmes...
November 15, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29143259/adsorption-reduction-of-hg-ii-and-pb-ii-from-aqueous-solutions-by-using-bone-ash-nzvi-composite-effects-of-aging-time-fe-loading-quantity-and-co-existing-ions
#10
Antonio Gil, Mohammad Javad Amiri, Jahangir Abedi-Koupai, Saeid Eslamian
In this research, a versatile and highly efficient method for the stabilization of nanoscale zerovalent iron particles (nZVI) on the surface of ostrich bone ash (OBA) was presented as a novel inorganic adsorbent (OBA/nZVI) for the removal of Hg(II) and Pb(II) ions from aqueous solutions, even after 1 year of storage under room conditions. The removal behavior of the OBA/nZVI was assessed as a function of the initial pH, contact time, initial pollutants concentration, temperature, amount of adsorbent, effect of competitive metal ions, and ionic strength...
November 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29143126/-spinal-orthoses-in-the-treatment-of-vertebral-fractures-with-osteoporosis-a-systematic-review-article
#11
REVIEW
M Pfeifer, M Gehlen, C Hinz
This literature search concerning the potential role of spinal orthoses for rehabilitation and treatment of atraumatic vertebral fractures between Th4 and L5 with osteoporosis and without any evidence for a secondary cause, provided no evidence for the benefits of traditional rigid thoracolumbar corsets, which only had a poor compliance. In addition, there are indications that these rigid corsets may even worsen the disease condition especially in the long-term. Wearing these corsets can result in further loss of muscle mass and strength followed by loss of bone and bone mass...
November 15, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29142879/effect-of-water-storage-on-flexural-strength-of-silorane-and-methacrylate-based-composite-resins
#12
Narges Panahandeh, Hassan Torabzadeh, Hani Naderi, Seyedeh Mahsa Sheikh-Al-Eslamian
Objectives: This study assessed the effect of water storage on the flexural strength (FS) of low shrinkage composites. Materials and Methods: A total of 165 bar-shaped specimens (2 × 2 × 25 mm) were fabricated of 2 low shrinkage composites (Filtek P90 [3M ESPE], GC Kalore [GC International]) and a conventional methacrylate-based composite (Filtek Z250 [3M ESPE]). The specimens were subjected to 3-point bending test at 6 time intervals, namely: immediately after curing, at 24 hours, 1 week, 1 month, 6 months, and 1 year following storage in wet and dry conditions...
November 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29142644/repair-bond-strengths-of-non-aged-and-aged-resin-nanoceramics
#13
Meryem Gülce Subaşı, Gülce Alp
PURPOSE: To explore the influence of different surface conditionings on surface changes and the influence of surface treatments and aging on the bond strengths of composites to non-aged and aged resin nanoceramics. MATERIALS AND METHODS: Rectangular-shaped non-aged and aged (5000 thermocycles) resin nanoceramic specimens (Lava Ultimate) (n=63, each) were divided into 3 groups according to surface treatments (untreated, air abrasion, or silica coating) (n=21). The surface roughness was measured and scanning electron microscopy was used to examine one specimen from each group...
October 2017: Journal of Advanced Prosthodontics
https://www.readbyqxmd.com/read/29142296/the-dopamine-motive-system-implications-for-drug-and-food-addiction
#14
REVIEW
Nora D Volkow, Roy A Wise, Ruben Baler
Behaviours such as eating, copulating, defending oneself or taking addictive drugs begin with a motivation to initiate the behaviour. Both this motivational drive and the behaviours that follow are influenced by past and present experience with the reinforcing stimuli (such as drugs or energy-rich foods) that increase the likelihood and/or strength of the behavioural response (such as drug taking or overeating). At a cellular and circuit level, motivational drive is dependent on the concentration of extrasynaptic dopamine present in specific brain areas such as the striatum...
November 16, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29142059/recovery-of-attention-with-renewal
#15
James Byron Nelson, Paul Craddock, Mikael Molet, Charlotte Renaux
One experiment determined the relationship between renewed associative strength and attention. Following cue1-outcome pairings in Context A, cue1 was extinguished in Context B while cue2 was conditioned. On test cue2 was chosen as a predictor of the outcome in Context B. Both cues were chosen equally often as predictors in Context A. Consistent with attributing attention to effective associative strength (as noted in a previous study), participants could locate only cue2 in Context B while both were located in Context A, regardless of having been chosen as a predictor...
December 2017: Learning & Memory
https://www.readbyqxmd.com/read/29141853/the-effects-of-resistance-exercise-on-biomarkers-of-breast-cancer-prognosis-a-pooled-analysis-of-three-randomized-trials
#16
Kerri Winters-Stone, Lisa J Wood, Sydnee Stoyles, Nathan Dieckmann
BACKGROUND: Using a secondary data analysis from randomized controlled trials comparing one year of resistance exercise (N=109) to a placebo control condition (N=106) in postmenopausal, post-treatment breast cancer survivors, we investigated the influence of resistance training and changes in body composition on markers associated with cancer progression. METHODS: Measures included serum levels of insulin, IGF-1, IGFBP1-3, leptin, serum amyloid A (SAA), adiponectin, C-reactive protein (CRP), IL-1β, TNF-α, IL-6, and IL-8 and body composition (total, lean and fat mass in kg) by DXA at baseline, 6, and 12-months...
November 15, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29141614/differences-in-the-prevalence-of-hospitalizations-and-utilization-of-emergency-outpatient-services-for-ambulatory-care-sensitive-conditions-between-asylum-seeking-children-and-children-of-the-general-population-a-cross-sectional-medical-records-study-2015
#17
Célina Lichtl, Thomas Lutz, Joachim Szecsenyi, Kayvan Bozorgmehr
BACKGROUND: Hospitalizations for ambulatory care sensitive (ACS) conditions are established indicators for the availability and quality of ambulatory care. We aimed to assess the differences between asylum-seeking children and children of the general population in a German city with respect to (i) the prevalence of ACS hospitalizations, and (ii) the utilization of emergency outpatient services for ACS conditions. METHODS: Using anonymous account data, all children admitted to the University Hospital Heidelberg in 2015 were included in our study...
November 15, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29141472/the-quality-of-life-and-associated-factors-in-patients-on-maintenance-hemodialysis-a-multicenter-study-in-shanxi-province
#18
Xiaoshuang Zhou, Fuping Xue, Hui Wang, Yufeng Qiao, Guangzhen Liu, Liping Huang, Deqian Li, Shuanggui Wang, Qunyuan Wang, Larong Li, Rongshan Li
OBJECTIVES: To assess the quality of life (QOL) and factors affecting QOL in hemodialysis patients so as to improve QOL of dialysis patients and provide the basis for better clinical care. METHODS: A retrospective study was performed to assess the QOL and factors affecting QOL in hemodialysis patients. We recruited 125 patients who had been receiving hemodialysis for at least 2 years in the dialysis units of nine hospitals in Shanxi Province, China, and conducted a multi-center questionnaire survey between 1 May 2015 and 1 July 2016...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/29141152/tm-values-and-unfolded-fraction-can-predict-aggregation-rates-for-gcsf-variant-formulations-but-not-under-predominantly-native-conditions
#19
Mathew J Robinson, Paul Matejtschuk, Adrian F Bristow, Paul A Dalby
Protein engineering and formulation optimisation strategies can be taken to minimise protein aggregation in the biopharmaceutical industry. Short-term stability measures such as the mid-point transition temperature (Tm) for global unfolding provide convenient surrogates for longer-term (eg 2-year) degradation kinetics, with which to optimise formulations on practical time-scales. While successful in some cases, their limitations have not been fully evaluated or understood. Tm values are known to correlate with chemical degradation kinetics for wild-type granulocyte colony stimulating factor (GCSF) at pH 4-5...
November 15, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29141073/forces-of-tool-tissue-interaction-to-assess-surgical-skill-level
#20
Taku Sugiyama, Sanju Lama, Liu Shi Gan, Yaser Maddahi, Kourosh Zareinia, Garnette R Sutherland
Importance: The application of optimal forces between surgical instruments and tissue is fundamental to surgical performance and learning. To date, this force has not been measured clinically during the performance of microsurgery. Objectives: To establish a normative catalog of force profiles during the performance of surgery, to compare force variables among surgeons with different skill levels, and to evaluate whether such a force-based metric determines or differentiates skill level...
November 15, 2017: JAMA Surgery
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