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https://www.readbyqxmd.com/read/29150847/chronic-sun-exposure-is-associated-with-distinct-histone-acetylation-changes-in-human-skin
#1
S Ding, J Chen, Q Zeng, J Lu, L Tan, A Guo, J Kang, S Yang, Y Xiang, C Zuo, J Huang
BACKGROUND: Photoaging is attributed to continuous sunlight or artificial UV exposure and manifests the clinical and histological changes of skin. Epigenetic changes have been found to be involved in the pathogenesis of photoaging. However, the underlying mechanisms are unclear. OBJECTIVES: To analyse histone modification patterns in sun-exposed and non-exposed skins, and identify the abnormally histone modified-genes related to photoaging. METHODS: Skin biopsies were collected both from the outer forearm (sun-exposed area) and the buttock (sun-protected area) in 20 healthy middle-aged female volunteers...
November 18, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29146147/age-induced-and-photoinduced-changes-in-gene-expression-profiles-in-facial-skin-of-caucasian-females-across-6%C3%A2-decades-of-age
#2
Alexa B Kimball, Maria B Alora-Palli, Makio Tamura, Lisa A Mullins, Chieko Soh, Robert L Binder, Neil A Houston, Emily D Conley, Joyce Y Tung, Nikki E Annunziata, Charles C Bascom, Robert J Isfort, Bradley B Jarrold, Raghu Kainkaryam, Heather L Rocchetta, Dionne D Swift, Jay P Tiesman, Kazumi Toyama, Jun Xu, Xianghong Yan, Rosemarie Osborne
BACKGROUND: Intrinsic and extrinsic factors, including ultraviolet irradiation, lead to visible signs of skin aging. OBJECTIVE: We evaluated molecular changes occurring in photoexposed and photoprotected skin of white women 20 to 74 years of age, some of whom appeared substantially younger than their chronologic age. METHODS: Histologic and transcriptomics profiling were conducted on skin biopsy samples of photoexposed (face and dorsal forearm) or photoprotected (buttocks) body sites from 158 women...
November 14, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29143471/ethnic-differences-in-stratum-corneum-functions-between-chinese-and-thai-infants-residing-in-bangkok-thailand
#3
Tsutomu Fujimura, Yuki Miyauchi, Kyoko Shima, Mitsuyuki Hotta, Hisashi Tsujimura, Takashi Kitahara, Yoshinori Takema, Pakhawadee Palungwachira, Diane Laohathai, Jetchawa Chanthothai, Thamthiwat Nararatwanchai
BACKGROUND/OBJECTIVES: Ethnic and racial differences in infant skin have not been well characterized. The purpose of this study was to establish whether there are ethnic differences and similarities in the stratum corneum (SC) functions of Thai and Chinese infants. METHODS: Healthy infants 6 to 24 months of age (N = 60; 30 Thai, 30 Chinese) who resided in Bangkok, Thailand, were enrolled. Transepidermal water loss (TEWL) and SC hydration (capacitance) on the thigh, buttock, and upper arm were measured...
November 15, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29140894/incontinence-associated-dermatitis-and-immobility-as-pressure-injury-risk-factors-a-multisite-epidemiologic-analysis
#4
Mikel Gray, Karen K Giuliano
PURPOSE: The purpose of this study was to measure the prevalence of incontinence-associated dermatitis (IAD) among incontinent persons in the acute care setting, characteristics of IAD in this group, and associations among IAD, urinary, fecal, and dual incontinence, immobility, and pressure injury in the sacral area. DESIGN: Descriptive and correlational analysis of data from a large database of IAD, and pressure injuries of sacral area and heels. SUBJECTS AND SETTING: The sample comprised 5342 adult patients in acute care facilities in 36 states representing all regions of the United States...
November 14, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/29139372/two-cases-of-lepromatous-leprosy-from-exposure-to-armadillos-in-florida
#5
Jennifer Harb, Salma Pothiawala, Donna Yonkosky, James Talley, Drazen Jukic
The first patient was a 41-year-old white man who was referred to the dermatology clinic with a 2-year history of numerous erythematous, hypoesthetic, poorly demarcated papules and plaques present on the trunk, buttocks, and bilateral upper and lower extremities (Figures 1 and 2). The lesions had initially begun as localized erythematous plaques on the right flank, and were diagnosed and treated as cellulitis and allergic contact dermatitis by primary care on separate occasions, with no resolution and continued gradual but persistent spread...
2017: Skinmed
https://www.readbyqxmd.com/read/29139370/perianal-ulcer-in-an-asian-man
#6
Nilanthy Sharon Anthony Pillai, Choon Chiat Oh, Michelle Chan Mei Fung, Limin Wijaya
A 79-year-old Chinese man presented with a 2-month history of pruritic, tender ulceration covering his perianal region. He was initially treated with oral amoxicillin/clavulanic acid and vancyclovir, with no improvement. His history included hypertension. On physical examination, there was a 1.5-cm solitary, pink shallow ulcer with a tender erythematous base on the right side of the buttock cleft (Figure 1).
2017: Skinmed
https://www.readbyqxmd.com/read/29135892/-lower-body-lift-in-the-massive-weight-loss-patient-a-new-classification-and-algorithm-for-gluteal-augmentation
#7
Taliah Schmitt, Samer Jabbour, Rani Makhoul, Warren Noel, Anne-Sophie Reguesse, Philippe Levan
BACKGROUND: An often neglected part of the lower body lift procedure is the gluteal region. The objective of this study is to classify the massive weight loss (MWL) patients undergoing a body lift procedure and provide a safe, standardized approach for gluteal augmentation. METHODS: A retrospective review of all body lift procedures performed between January 2012 and January 2017 was conducted. Patients undergoing a lower body lift with or without gluteal augmentation were included for analysis...
November 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29135509/unilesional-follicular-mycosis-fungoides-report-of-6-cases-and-review-of-the-literature
#8
Cynthia M Magro, Gladys H Telang, Shabnam Momtahen
Unilesional follicular mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma characterized by selective involvement of the hair follicles by neoplastic T lymphocytes presenting initially as a solitary lesion occupying less than 5% of the body surface; there are 22 previous reported cases. We describe 6 patients with this rare variant of MF, all males (age range 6-64 years; mean age: 28 years) presenting with a solitary lesion primarily on the face and scalp except 1 patient who presented with a truncal lesion...
October 24, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29133295/head-injury-mechanisms-in-fis-world-cup-alpine-and-freestyle-skiers-and-snowboarders
#9
Sophie Elspeth Steenstrup, Arnhild Bakken, Tone Bere, Declan Alexander Patton, Roald Bahr
INTRODUCTION: Head injuries represent a concern in skiing and snowboarding, with traumatic brain injuries being the most common cause of death. AIM: To describe the mechanisms of head and face injuries among World Cup alpine and freestyle skiers and snowboarders. METHODS: We performed a qualitative analysis of videos obtained of head and face injuries reported through the International Ski Federation Injury Surveillance System during 10 World Cup seasons (2006-2016)...
November 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29132044/exposure-to-thin-ideal-media-affect-most-but-not-all-women-results-from-the-perceived-effects-of-media-exposure-scale-and-open-ended-responses
#10
David A Frederick, Elizabeth A Daniels, Morgan E Bates, Tracy L Tylka
Findings conflict as to whether thin-ideal media affect women's body satisfaction. Meta-analyses of experimental studies reveal small or null effects, but many women endorse appearance-related media pressure in surveys. Using a novel approach, two samples of women (Ns=656, 770) were exposed to bikini models, fashion models, or control conditions and reported the effects of the images their body image. Many women reported the fashion/bikini models made them feel worse about their stomachs (57%, 64%), weight (50%, 56%), waist (50%, 56%), overall appearance (50%, 56%), muscle tone (46%, 52%), legs (45%, 48%), thighs (40%, 49%), buttocks (40%, 43%), and hips (40%, 46%)...
November 10, 2017: Body Image
https://www.readbyqxmd.com/read/29129546/solitary-intraosseous-myofibroma-of-the-ilium-in-an-adult-patient-a-case-report-and-literature-review
#11
Hiroyuki Tsuchie, Giuseppe Bianchi, Marco Gambarotti, Davide Maria Donati
BACKGROUND: Myofibroma is a rare benign tumor typically occurring in the skin and subcutaneous tissues of the head and neck in infants and young children. The incidence of solitary intraosseous and adult myofibroma is extremely low. Although there have been a few reported cases of solitary intraosseous myofibroma in adult patients, most of these cases involved the craniofacial bones. METHODS: We present the case of a 64-years-old woman presenting with minimal pain of the right buttock and groin...
November 9, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29123372/the-effect-of-musculoskeletal-problems-on-fatigue-and-productivity-of-office-personnel-a-cross-sectional-study
#12
REVIEW
H Daneshmandi, A R Choobineh, H Ghaem, M Alhamd, A Fakherpour
Introduction: Work-related Musculoskeletal Disorders (WMSDs) can impact on fatigue and productivity of office workers. This study aimed to investigate the effect of musculoskeletal problems on fatigue and productivity among office personnel. Methods: This study was performed on 101 Iranian office workers. Data were gathered through a demographic questionnaire, Nordic Musculoskeletal Questionnaire, Numeric Rating Scale, Persian version of Multidimensional Assessment of Fatigue Scale, and Persian version of Health and Work Questionnaire...
September 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/29113207/brain-metastatic-alveolar-soft-part-sarcoma-clinicopathological-profiles-management-and-outcomes
#13
Xiaogang Tao, Zonggang Hou, Zhen Wu, Shuyu Hao, Baiyun Liu
Alveolar soft-part sarcoma (ASPS) is a rare sarcoma that presents in the buttocks or thigh of young adults and often metastasizes to the brain. The present study examined the clinical features and morphology of brain metastatic ASPS. The case records of eight patients with brain metastatic ASPS admitted between November 2008 and March 2015 were reviewed. The relevant clinical data (including patient age and sex, neuroimaging studies, histopathological and immunohistochemical features, surgical records and follow-up reports) were collected through a review of patient records...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29109885/sacral-stress-fracture-in-an-amateur-badminton-player
#14
Yusuke Yuasa, Naohisa Miyakoshi, Michio Hongo, Kunio Ebata, Tatsuru Tomioka, Yoichi Shimada
Sacral stress fractures are rare among athletes but have been reported most frequently in long distance runners. We report herein the first case of a sacral stress fracture in an amateur badminton player. A 16-year-old, left-handed adolescent girl, who had just started to play badminton 3 months previously, complained of acute left buttock pain when she received a shuttlecock. Magnetic resonance imaging revealed a linear lesion of the left sacrum with low signal intensity on T1- and high signal intensity on T2-weighted images, which was consistent with a stress fracture...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29105985/do-body-build-and-composition-influence-striae-distensae-occurrence-and-visibility-in-women
#15
Anna Kasielska-Trojan, Bogusław Antoszewski
BACKGROUND: Striae have been reported to be one of the most common skin changes and a commonly encountered esthetic problem. OBJECTIVES: To analyze risk factors of striae not associated with pregnancy and verify if body build and composition influence striae distensae (SD) occurrence and visibility. METHODS: Eighty female students (40 with striae (the mean age 23.9 years, SD 2.05 years) and 40 without these lesions (24.7 years, SD 6.2 years)) were included in the study...
November 6, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29103774/a-single-arm-open-label-clinical-trial-of-autologous-epidermal-cell-transplantation-for-stable-vitiligo-a-30-month-follow-up
#16
Zahra Orouji, Amir Bajouri, Mahshid Ghasemi, Parvaneh Mohammadi, Nasrin Fallah, Atefeh Shahbazi, Mohammad Rezvani, Fatemeh Vaezirad, Zahra Khalajasadi, Ahad Alizadeh, Ehsan Taghiabadi, Sara Dashtbozorgi, Raheleh Aghdami, Seyedeh Esmat Hosseini, Hossein Bahahrvand, Saeed Shafieyan, Nasser Aghdami
BACKGROUND: Recently, we introduced intralesional injection of autologous epidermal cells as a safe and feasible approach for transplantation in patients with stable vitiligo. This approach resulted in less pain during and after the procedure, no scarring or cobblestone formation at the recipient site, and was more feasible to perform on curved surfaces such as joints, lips, eyelids, ears, and face. OBJECTIVE: In this study, we aimed to investigate the long-term efficacy and safety of this transplantation technique...
October 18, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29098152/properties-of-skin-in-chinese-infants-developmental-changes-in-ceramides-and-in-protein-secondary-structure-of-the-stratum-corneum
#17
Chao Yuan, Ying Zou, Yao Xueqiu, Kyoko Shima, Yuki Miyauchi, Ayano Naoe, Satoru Naito, Tsutomu Fujimura, Mitsuyuki Hotta, Takashi Kitahara, Xuemin Wang
The properties of infant skin regarding its structure and stratum corneum (SC) properties during development compared to adult skin have been reported only for a few races and body sites. The aim of this study was to understand the developmental changes of skin properties in Chinese infants, focusing on SC ceramides and protein secondary structure, which are important for skin barrier function. Three body sites with distinct characteristics (cheeks, inner upper arms, and buttocks) were assessed. Sixty pairs of Chinese infants and their mothers were measured for SC hydration, transepidermal water loss, ceramide levels, sebum with an ester bond, and protein secondary structure of superficial SC...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29092870/specialty-linens-and-pressure-injuries-in-high-risk-patients-in-the-intensive-care-unit
#18
Regi Freeman, Andrew Smith, Sharon Dickinson, Dana Tschannen, Shandra James, Candace Friedman
BACKGROUND: The cardiovascular and surgical intensive care units had the highest unit-acquired pressure injury rates at an institution. Patients in these units had multiple risk factors for pressure injuries. Various interventions had been used to minimize pressure injuries, with limited results. OBJECTIVES: To evaluate the effect of specialty linens on the rate of pressure injuries in high-risk patients. The specialty linen was a synthetic silklike fabric that addressed the microclimate surrounding the patient, with the purpose of minimizing friction, shear, moisture, and heat...
November 2017: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/29091038/assessment-of-the-biomechanical-effects-of-prophylactic-sacral-dressings-on-tissue-loads-a-computational-modeling-analysis
#19
Ayelet Levy, Amit Gefen
The sacrum is the most susceptible anatomical site for developing pressure injuries, including deep tissue injuries, during supine lying. Prophylactic dressings generally are designed to reduce friction, alleviate internal tissue shear, manage the microclimate, and overall cushion the soft tissues subjected to sustained deformations under the sacrum. Using computational modeling, the authors developed a set of 8 magnetic resonance imaging-based, 3-dimensional finite element models of the buttocks of a healthy 28-year-old woman for comparing the biomechanical effects of different prophylactic sacral dressing designs when used during supine lying on a standard hospital foam mattress...
October 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/29090455/furuncular-myiasis-for-the-western-dermatologist-treatment-in-outpatient-consultation
#20
Romain Blaizot, Christophe Vanhecke, Philippe Le Gall, Alexandre Duvignaud, Marie-Catherine Receveur, Denis Malvy
BACKGROUND: Furuncular myiasis is likely to be seen by Western dermatologists because of the increasing number of international travelers but remains unfamiliar to most of them, who tend to refer these patients to hospitals. Different treatments have been proposed, but many of them are not achievable in outpatient consultation. METHODS: We reported three typical cases of furuncular myiasis, according to each species involved, and proposed diagnostic and therapeutic guidelines for dermatologists in outpatient consultation...
October 31, 2017: International Journal of Dermatology
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