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Fatt transfer

Norazreen Zakaria, Muhammad Zaki Ramli, Kalavathy Ramasamy, Lim Siong Meng, Chan Yean Yean, Kirnpal Kaur Banga Singh, Zainiharyati Mohd Zain, Kim-Fatt Low
A miniaturized biosensing platform, based on monoclonal amyloid-beta antibodies (mAβab ) that were immobilized on a disc-shaped platinum/iridium (Pt/Ir) microelectrode surface coupled with an impedimetric signal transducer, was developed for the label-free and sensitive detection of amyloid-beta peptide fragment 1-40 (Aβ40); a reliable biomarker for early diagnosis of Alzheimer's disease (AD). A Pt/Ir microelectrode was electropolymerized with poly (ortho-phenylenediamine), a conducting free amine-containing aromatic polymer; followed by crosslinking with glutaraldehyde for subsequent coupling of mAβab on the microelectrode surface...
June 4, 2018: Analytical Biochemistry
Hong Fang Lu, Sze-Xian Lim, Meng Fatt Leong, Karthikeyan Narayanan, Rebecca P K Toh, Shujun Gao, Andrew C A Wan
Developing an efficient culture system for controlled human pluripotent stem cell (hPSC) differentiation into selected lineages is a major challenge in realizing stem cell-based clinical applications. Here, we report the use of chitin-alginate 3D microfibrous scaffolds, previously developed for hPSC propagation, to support efficient neuronal differentiation and maturation under chemically defined culture conditions. When treated with neural induction medium containing Noggin/retinoic acid, the encapsulated cells expressed much higher levels of neural progenitor markers SOX1 and PAX6 than those in other treatment conditions...
December 2012: Biomaterials
Veeranoot Nissapatorn, Christopher Lee, Kia Fatt Quek, Chee Loon Leong, Rohela Mahmud, Khairul Anuar Abdullah
The seroprevalence of toxoplasmosis among 505 of human immunodeficiency virus (HIV)/AIDS patients was 226 (44.8%; 95% CI 42.64-51.76): 27 (47.4%) and 199 (44.4%) showed Toxoplasma seropositivity with and without toxoplasmic encephalitis (TE), respectively (P <0.05). The majority of these patients were in the 25-34 age group (44 versus 39%), male (86 versus 76%), and Chinese (49 versus 53%), though no statistical significance was found between the two. Significant differences between these two groups were noted, however, in terms of marital status, occupation, and present address...
August 2004: Japanese Journal of Infectious Diseases
The rate of transfer of labeled molecules across a sheet of quiescent cat right ventricle separating two chambers containing chemically identical solutions was followed at 23 degrees C. For the diffusion of sucrose, SO(4), and Na the experimental points fit the entire time course of the plot of the diffusion equation for a plane sheet. The tortuosity factor of the extracellular diffusion channel, lambda was 1.44 +/- 0.05 (mean +/- SEM) for sucrose and similar for SO(4) and Na. The fractional area available for extracellular diffusion, calculated from lambda and the slope of the linear asymptote approached during steady state diffusion, was 0...
July 1964: Journal of General Physiology
G Falk, P Fatt
No abstract text is available yet for this article.
August 1974: Vision Research
J H Belgum, D R Copenhagen
1. Simultaneous intracellular recordings of responses to light flashes were obtained from rod-horizontal cell and rod-hyperpolarizing bipolar cell pairs in isolated retinae of the toad. The gain and temporal filtering of synaptic transfer were characterized throughout the rods' range of light responses. 2. Paired rod-horizontal cell and rod-bipolar cell responses to dim flashes (less than 0.4 Rh*, where Rh* denotes effective photoisomerizations per rod per flash) exhibited nearly the same time course. Analysis of the onset of the horizontal cell responses revealed a temporal lag equivalent to a single stage of low-pass filtering (tau f = 75-200 ms)...
February 1988: Journal of Physiology
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