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Phytochemical medicine

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https://www.readbyqxmd.com/read/28424705/contemporary-understanding-of-mirna-based-regulation-of-secondary-metabolites-biosynthesis-in-plants
#1
REVIEW
Om P Gupta, Suhas G Karkute, Sagar Banerjee, Nand L Meena, Anil Dahuja
Plant's secondary metabolites such as flavonoids, terpenoids, and alkaloids etc. are known for their role in the defense against various insects-pests of plants and for medicinal benefits in human. Due to the immense biological importance of these phytochemicals, understanding the regulation of their biosynthetic pathway is crucial. In the recent past, advancement in the molecular technologies has enabled us to better understand the proteins, enzymes, genes, etc. involved in the biosynthetic pathway of the secondary metabolites...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28421120/in-vitro-and-in-vivo-studies-on-quercus-acuta-thunb-fagaceae-extract-active-constituents-serum-uric-acid-suppression-and-xanthine-oxidase-inhibitory-activity
#2
In-Soo Yoon, Dae-Hun Park, Min-Suk Bae, Deuk-Sil Oh, Nan-Hui Kwon, Jung-Eun Kim, Chul-Yung Choi, Seung-Sik Cho
Quercus acuta Thunb. (Fagaceae) (QA) is cultivated as a dietary and ornamental plant in China, Japan, South Korea, and Taiwan. It has been widely used as the main ingredient of acorn tofu, a traditional food in China and South Korea. The aim of this study was to determine in vitro and in vivo xanthine oxidase (XO) inhibitory and antihyperuricemic activities of an ethyl acetate extract of QA leaf (QALE) and identify its active phytochemicals using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography (LC) systems...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28417090/role-of-traditional-islamic-and-arabic-plants-in-cancer-therapy
#3
REVIEW
Rizwan Ahmad, Niyaz Ahmad, Atta Abbas Naqvi, Adeeb Shehzad, Mastour Safer Al-Ghamdi
ETHNO PHARMACOLOGICAL RELEVANCE: This review article underlines individual Traditional Islamic and Arabic plant (TAI) and their role in treating cancer. The aim of the study is to specifically evaluate the progress of herbs, Arabic and Islamic traditional herbs in particular, applied in cancer treatment, so far. MATERIALS AND METHODS: Islamic and Arabic plants were selected and identified through different literature survey using "Google scholar", "Web of science", "Scopus" and "PubMed"...
April 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28417084/antioxidant-antimicrobial-activity-and-bioactive-compounds-of-bergenia-ciliata-sternb-a-valuable-medicinal-herb-of-sikkim-himalaya
#4
Mithilesh Singh, Neha Pandey, Vasudha Agnihotri, K K Singh, Anita Pandey
Bergenia ciliata Sternb., commonly known as Paashaanbhed, is a well known herb of Sikkim Himalaya with various pharmaceutical properties. However, scientific exploration of B. ciliata, growing in the Sikkim Himalaya, for phytochemicals and pharmacological properties is in infancy. With this view, the present study was undertaken to investigate B. ciliata leaf extracts for antioxidant, antimicrobial activity and bioactive compounds. Three solvents viz., methanol, ethyl acetate and hexane were used for extraction and the respective leaf extracts were analyzed for total phenolic and flavonoid contents along with the antioxidant and antimicrobial activities...
April 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28411365/analysis-of-glycosylated-flavonoids-extracted-from-sweet-cherry-stems-as-antibacterial-agents-against-pathogenic-escherichia-coli-isolates
#5
Alfredo Aires, Carla Dias, Rosa Carvalho, Maria José Saavedra
The aim of this study was to evaluate the bioactivity of flavonoids extracted from sweet-cherry stems which are often used by a traditional system of medicine to treat gastro-intestinal and urinary tract infections but lacking any consistent scientific evidence; moreover the information about the class of phenolics, their content and the potential bioactivity of such material is very scarce. Thus, in this context, we have set a research study in which we evaluated the profile and content of phenolics extracted from sweet-cherry stems through a conventional (70ºC and 20 min) and ultrasound assisted extraction (40 kHz, room temperature and 20 min)...
April 14, 2017: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/28409159/nutritional-composition-and-phytochemical-antioxidative-and-antifungal-activities-of-pergularia-tomentosa-l
#6
Imen Lahmar, Hafedh Belghith, Ferjani Ben Abdallah, Karima Belghith
Crude extracts from a medicinal Tunisian plant, Pergularia tomentosa L., were the investigated natural material. Butanolic extract of roots analyzed with IR spectra revealed the presence of hydroxyl, alcoholic, and carboxylic groups and sugars units. Analysis of some secondary metabolites, total phenolic, flavonoids, flavonols, and procyanidins, was performed using different solvents following the increased gradient of polarity. Fruits and leaves contained the highest amounts of all these compounds. Antioxidant properties were evaluated by the determination of free radical scavenging activity and the reducing power of methanolic extracts...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28406728/clinical-evaluation-of-a-polyherbal-nutritional-supplement-in-dyslipidemic-volunteers
#7
Subramanian Suganya, Subapriya Natarajan, Duraipandian Chamundeeswari, Anand Anbarasu, Kunissery A Balasubramanian, Lynn C Schneider, Balaji Nandagopal
Ten important plant parts routinely used in South Indian ethnic food preparation as spices and condiments were investigated for their potential antidyslipidemic properties. The aim of the study was to characterize the biochemical properties of the polyherbal formulation (nutritional supplement) and evaluate its use to control dyslipidemia in patients. Phytochemical evaluation, in vitro α-amylase inhibitory assay, and high performance thin layer chromatography (HPTLC) fingerprinting were carried out with alcoholic extracts of all 10 individual plants and with the nutritional supplement...
April 13, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28403651/phytochemical-components-total-phenol-and-mineral-contents-and-antioxidant-activity-of-six-major-medicinal-plants-from-rayen-iran
#8
Naser Boroomand, Mohammad Sadat-Hosseini, Mojtaba Moghbeli, Mostafa Farajpour
The aim of this work was to evaluate the phytochemical components, minerals, the antioxidant activity and total phenol contents of the essential oil from aerial parts of six major medicinal plants in Rayen, Iran. The plants included Ranunculus arvensis, Teucrium polium, Dracocephalum polychaetum, Kelussia odoratissima, Artemisia sieberi and Thymus kotschyanus. Total phenol content ranged from 0.03 to 0.158 mg/mL. A. sieberi showed the highest radical scavenging ability (IC50 = 94 μg/mL). The amount of minerals ranged as follows: P (0...
April 13, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28397551/biological-effects-and-clinical-applications-of-dwarf-elder-sambucus-ebulus-l-a-review
#9
Marzie Jabbari, Babak Daneshfard, Majid Emtiazy, Ali Khiveh, Mohammad Hashem Hashempur
Dwarf elder ( Sambucus ebulus L) is one of the best known medicinal herbs since ancient times. In view of its benefits as a widely applicable phytomedicine, it is still used in folk medicine of different parts of the world. In addition to its nutritional values, dwarf elder contains different phytochemicals among which flavonoids and lectins are responsible for most of its therapeutic effects. Dwarf elder has been used for different ailments including: joint pains, cold, wounds, and infections. Nevertheless, recent evidence has revealed its potentials for making attempts at treating cancer and metabolic disorders...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/28392893/traditional-persian-topical-medications-for-gastrointestinal-diseases
#10
REVIEW
Laleh Dehghani Tafti, Seyyed Mahyar Shariatpanahi, Mahmoud Mahdavi Damghani, Behjat Javadi
Drug delivery across the skin is used for several millennia to ease gastrointestinal (GI) ailments in Traditional Persian Medicine (TPM). TPM topical remedies are generally being applied on the stomach, lower abdomen, lower back and liver to alleviate GI illnesses such as dyspepsia, gastritis, GI ulcers, inflammatory bowel disease, intestinal worms and infections. The aim of the present study is to survey the topical GI remedies and plant species used as ingredients for these remedies in TPM. In addition, pharmacological activities of the mentioned plants have been discussed...
March 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28392456/anti-inflammatory-activity-of-crateva-adansonii-dc-on-keratinocytes-infected-by-staphylococcus-aureus-from-traditional-practice-to-scientific-approach-using-hptlc-densitometry
#11
Kplolali Ahama-Esseh, Charles Bodet, Akossiwa Quashie-Mensah-Attoh, Magali Garcia, Isabelle Théry-Koné, Joelle Dorat, Comlan De Souza, Cécile Enguehard-Gueiffier, Leslie Boudesocque-Delaye
ETHNOPHARMACOLIGICAL RELEVANCE: Leaves of Crateva adansonii DC (Capparidaceae), a small bush found in Togo, are widely used in traditional medicine to cure infectious abscesses. Traditional healers of Lomé harvest only budding leaves early in the morning, in specific area in order to prepare their drugs. AIM OF THE STUDY: The main goal was to validate the ancestral picking practices, and to assess the activity of C. adansonii medicine towards infectious abscesses...
April 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28391699/chemoprevention-of-colorectal-cancer-by-artocarpin-a-dietary-phytochemical-from-artocarpus-heterophyllus
#12
Guochuan Sun, Zongping Zheng, Mee-Hyun Lee, Yijuan Xu, Soouk Kang, Zigang Dong, Mingfu Wang, Zhennan Gu, Haitao Li, Wei Chen
Artocarpus heterophyllus is an evergreen tree distributed in tropical regions, and its fruit (jackfruit) is well-known as the world's largest tree-borne fruit. Although A. heterophyllus has been widely used in folk medicines against inflammation, its potential in cancer chemoprevention remains unclear. Herein we identified artocarpin from A. heterophyllus as a promising colorectal cancer chemopreventive agent by targeting Akt kinase. Phenotypically, artocarpin exhibited selective cytotoxicity against human colon cancer cells...
April 18, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28386582/preliminary-phytochemical-screening-quantitative-analysis-of-alkaloids-and-antioxidant-activity-of-crude-plant-extracts-from-ephedra-intermedia-indigenous-to-balochistan
#13
Rahman Gul, Syed Umer Jan, Syed Faridullah, Samiullah Sherani, Nusrat Jahan
The aim of this study was to evaluate the antioxidant activity, screening the phytogenic chemical compounds, and to assess the alkaloids present in the E. intermedia to prove its uses in Pakistani folk medicines for the treatment of asthma and bronchitis. Antioxidant activity was analyzed by using 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay. Standard methods were used for the identification of cardiac glycosides, phenolic compounds, flavonoids, anthraquinones, and alkaloids. High performance liquid chromatography (HPLC) was used for quantitative purpose of ephedrine alkaloids in E...
2017: TheScientificWorldJournal
https://www.readbyqxmd.com/read/28384001/comparative-phytochemical-analysis-of-chinese-and-bay-starvine-schisandra-spp-potential-for-development-as-a-new-dietary-supplement-ingredient
#14
James T Lyles, Paula Tyler, E Jane Bradbury, Kate Nelson, Carl F Brown, Stefanie T Pierce, Cassandra L Quave
Schisandra chinensis (Chinese starvine) is a popular dietary supplement with a rich history of use in traditional Chinese medicine. Schisandra glabra (bay starvine) is the only North American representative of the genus, and little is known about its history of traditional use, chemistry, and potential biological activity. In this study, we conducted comparative high-performance liquid chromatography-diode array detector (HPLC-DAD) analysis on S. glabra and S. chinensis fruits. Additional characterization of S...
April 6, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28382454/current-state-and-prospects-of-the-phytosynthesized-colloidal-gold-nanoparticles-and-their-applications-in-cancer-theranostics
#15
REVIEW
Muhammad Ovais, Abida Raza, Shagufta Naz, Nazar Ul Islam, Ali Talha Khalil, Shaukat Ali, Muhammad Adeeb Khan, Zabta Khan Shinwari
The design, development, and biomedical applications of phytochemical-based green synthesis of biocompatible colloidal gold nanoparticles (AuNPs) are becoming an emerging field due to several advantages (safer, eco-friendly, simple, fast, energy efficient, low-cost, and less toxic) over conventional chemical synthetic procedures. Biosynthesized colloidal gold nanoparticles are remarkably attractive in several biomedical applications including cancer theranostics due to small size, unusual physico-chemical properties, facile surface modification, high biocompatibility, and numerous other advantages...
April 5, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28376868/evaluation-of-the-anti-diarrheal-activity-of-the-aqueous-stem-extract-of-lantana-camara-linn-verbenaceae-in-mice
#16
Edlam Tadesse, Ephrem Engidawork, Teshome Nedi, Getnet Mengistu
BACKGROUND: Diarrheal disease remains a public health problem in developing countries, including Ethiopia. In order to alleviate this disease, Ethiopian traditional healers use a wide range of medicinal plants from which Lantana camara is one of them. The stem of this plant is traditionally used for the treatment of diarrhoea. In addition, this plant is scientifically evaluated to have an antispasmodic effect on in vitro study. The aim of this study was to evaluate the antidiarrheal activity of the aqueous stem extract of L...
April 4, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28375136/review-antiurolithiatic-plants-formulations-used-in-different-countries-and-cultures
#17
Salman Ahmed, Muhammad Mohtasheemul Hasan, Zafar Alam Mahmood
About 12% of world population is affected by different forms of urolithiasis in which the recurrence rate in female is 47-60% and in male is 70-80%. According to WHO 75% people rely on traditional medicines for the prevention and cure of different ailments. Similarly, the majority of the world population use a number of plants to treat problems related to the urinary tract system in which urolithiasis is the major cause. The aim of the review is to collect the data of the plants used in different parts and cultures of the world against urolithiasis with their parts, mode of preparation, dosage and administration...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28372259/medicinal-plants-and-phytochemicals-with-anti-obesogenic-potentials-a-review
#18
REVIEW
Ramgopal Mopuri, Md Shahidul Islam
Human mortality has been significantly increased in last few decades due to the increased prevalence of obesity and associated chronic disorders such as type 2 diabetes, non-alcoholic fatty liver disease, coronary heart disease and atherosclerosis. Apart from genetic and medicine or drug related side effects, nearly 90-95% people became obese due to the imbalanced calorie intake and lack of nutritional knowledge. The anti-obesogenic drugs, Orlistat and Sibutramine, which have been duly approved by Food and Drug Administration (FDA), USA, work very well on diet-induced obesity however they are not getting popular to the people with overweight/obesity due to the higher cost and severe side effects...
March 29, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28371943/bioassay-guided-isolation-of-iridoids-and-phenylpropanoids-from-aerial-parts-of-lamium-album-and-their-anti-inflammatory-activity-in-human-neutrophils
#19
Monika E Czerwińska, Anita Świerczewska, Marta Woźniak, Anna K Kiss
In traditional medicine, flowers and aerial parts of Lamium album are assigned by their anti-inflammatory, antiseptic, and mucolytic activities, and are used in chronic bronchitis and pharyngitis as well as skin, vaginal, and cervical inflammation.The aim of the present study was to compare effects of ethanolic extracts prepared from flowers and aerial parts of L. album on selected functions of human neutrophils, which are involved in an inflammatory response. In order to identify the compounds engaged in the anti-inflammatory activity of extracts, the bioassay-guided isolation of compounds was performed based on the inhibition of cytokine secretion by stimulated neutrophils...
April 3, 2017: Planta Medica
https://www.readbyqxmd.com/read/28363524/a-systematic-overview-of-leucosidea-sericea-a-multi-purpose-tree-with-great-potential-as-phytomedicine
#20
REVIEW
Tshepiso C Mafole, Adeyemi O Aremu, Thandekile Mthethwa, Mack Moyo
ETHNOPHARMACOLOGICAL RELEVANCE: Leucosidea sericea is a tree species found in southern Africa and possess several therapeutical effects against infectious diseases in humans and livestock. Increasing evidence on the efficacy of the species have demonstrated noteworthy biological potential. AIMS OF THE REVIEW: To comprehensively document and summarize the botany, biological and phytochemical properties of Leucosidea sericea, a monotypic species in the genus Leucosidea...
March 28, 2017: Journal of Ethnopharmacology
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