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Smart pumps

Andrew A M Ibey, Derek Andrews, Barb Ferreira
The authors present a case in which a physical anomaly with an infusion pump resulted in an unforeseen fault that the nurse's attempts to resolve unknowingly exacerbated. This case study presents the first report in the literature to detail the difficulty in recreating a patient safety event using smart pump logs, support server continuous quality improvement (CQI) data, and the drug order entry system to elucidate the clinical scenario. A 75-year-old male patient presented to a major teaching hospital and was admitted to the intensive care unit (ICU) with a massive gastrointestinal bleed and myocardial infarction, then stabilized...
December 2016: Drug Saf Case Rep
Simon A Bello, Sharad Malavade, Christopher L Passaglia
Animal models of ocular hypertension are important for glaucoma research but come with experimental costs. Available methods of intraocular pressure (IOP) elevation are not always successful, the amplitude and time course of IOP changes are unpredictable and irreversible, and IOP measurement by tonometry is laborious. Here we present a novel system for monitoring and controlling IOP without these limitations. It consists of a cannula implanted in the anterior chamber of the eye, a pressure sensor that continually measures IOP, and a bidirectional pump driven by control circuitry that can infuse or withdraw fluid to hold IOP at user-desired levels...
September 27, 2016: Annals of Biomedical Engineering
Fazil E Uslu, Kerem Pekkan
Hydrodynamic performance of the marine mussel, Mytilus galloprovincialis, is studied with time-resolved particle image velocimetry. We evaluated inhalant flow, exhalant jet flow, suction performance and flow control capabilities of the mussels quantitatively. Inhalant flow structures of mussels are measured at the coronal plane for the first time in literature. Nutrient fluid is convected into the mussel by three-dimensional sink flow. Inhalant velocity reaches its highest magnitude inside the mussel mantle while it is accelerating outward from the mussels...
October 15, 2016: Biology Open
C E Morris, B Joos
Sick excitable cells (ie, Nav channel-expressing cells injured by trauma, ischemia, inflammatory, and other conditions) typically exhibit "acquired sodium channelopathies" which, we argue, reflect bleb-damaged membranes rendering their Nav channels "leaky." The situation is excitotoxic because untreated Nav leak exacerbates bleb damage. Fast Nav inactivation (a voltage-independent process) is so tightly coupled, kinetically speaking, to the inherently voltage-dependent process of fast activation that when bleb damage accelerates and thus left-shifts macroscopic fast activation, fast inactivation accelerates to the same extent...
2016: Current Topics in Membranes
Gudrun Dieberg, Neil A Smart, Nicola King
BACKGROUND: To reduce complications during coronary artery bypass grafting (CABG) off-pump CABG was introduced; however, results have been mixed. The aim of this work was to conduct a systematic review and meta-analysis of off-pump vs. on-pump CABG. METHODS: To identify potential studies systematic searches were carried out using various databases. The search strategy included the key concepts of "cardiopulmonary bypass" AND "coronary artery bypass grafting" AND "off pump"...
November 15, 2016: International Journal of Cardiology
Moninne Howlett, Michael Curtin, Dermot Doherty, Paula Gleeson, Michelle Sheerin, Cormac Breatnach
AIM: Wide scale implementation of paediatric standardised concentration infusions (SCIs) and the use of smart pump technology has been slow despite international safety agency recommendations. Implementation rates in European hospitals fall far below those in the United States, where for the last decade accreditation has been linked to implementation.1 2 Multidisciplinary collaboration is essential, with pharmacy input and the creation of a smart pump drug library recognised as often being limiting, yet crucial factors, to implementation...
September 2016: Archives of Disease in Childhood
Byeongyeon Kim, Young Ki Hahn, Dongwon You, Sein Oh, Sungyoung Choi
A smart multi-pipette for hand-held operation of microfluidic devices is presented and applied to cytotoxicity assays and micro-droplet generation. This method enables a continuous-flow and accurate pumping simply by pushing the plunger of the smart multi-pipette, thereby obviating the need for auxiliary equipment and special expertise in microfluidics. We applied the smart multi-pipette to a cytotoxicity assay using a gradient-generating device and water droplet generation using a T-junction device. In combination with general microfluidic devices, the smart multi-pipette enables the devices to successfully perform their own functions...
October 21, 2016: Analyst
Sara Arenas-López, Isabel M Stanley, Paul Tunstell, Virginia Aguado-Lorenzo, Jo Philip, Joanne Perkins, Andrew Durward, Miguel Angel Calleja-Hernández, Shane M Tibby
OBJECTIVE: To evaluate safety, following introduction of standard concentrations of morphine infusions in paediatric critical care. METHODS: Implementation: A multidisciplinary team was convened, and several workstreams designated, including derivation of concentrations, manufacturing, supply, prescribing, administration using smart pump technology, training and evaluation. Safety Evaluation: Retrieval of all existing data on medication errors linked to morphine use using our hospital incident reporting system and risk assessment of errors in relation to standard concentration implementation...
June 23, 2016: Journal of Pharmacy and Pharmacology
Dongliang Tian, Na Zhang, Xi Zheng, Guanglei Hou, Ye Tian, Yi Du, Lei Jiang, Shi Xue Dou
Controllable liquid transport on surface is expected to occur by manipulating the gradient of surface tension/Laplace pressure and external stimuli, which has been intensively studied on solid or liquid interface. However, it still faces challenges of slow response rate, and uncontrollable transport speed and direction. Here, we demonstrate fast responsive and controllable liquid transport on a smart magnetic fluid/nanoarray interface, i.e., a composite interface, via modulation of an external magnetic field...
June 28, 2016: ACS Nano
Hanna M Seidling, David W Bates
Health IT is becoming an increasingly powerful tool for improving medication safety. While errors may happen at all stages of the medication process, different tools have been developed to support the prescribing process (e.g. computerized prescribing with decision support), the dispensing process (e.g. barcoding or automated dispensing and unit-dose systems), or the administration process (e.g. electronic medication administration records and smart pumps). Health IT can reduce medication error and preventable adverse drug event rates by increasing documentation quality and transparency, enhancing accuracy and correctness of the medication process, and supporting information exchange and interlinking different stages of the medication process...
2016: Studies in Health Technology and Informatics
Amelia A Peters, Michael J G Milevskiy, Wei C Lee, Merril C Curry, Chanel E Smart, Jodi M Saunus, Lynne Reid, Leonard da Silva, Daneth L Marcial, Eloise Dray, Melissa A Brown, Sunil R Lakhani, Sarah J Roberts-Thomson, Gregory R Monteith
Regulation of Ca(2+) transport is vital in physiological processes, including lactation, proliferation and apoptosis. The plasmalemmal Ca(2+) pump isoform 2 (PMCA2) a calcium ion efflux pump, was the first protein identified to be crucial in the transport of Ca(2+) ions into milk during lactation in mice. In these studies we show that PMCA2 is also expressed in human epithelia undergoing lactational remodeling and also report strong PMCA2 staining on apical membranes of luminal epithelia in approximately 9% of human breast cancers we assessed...
2016: Scientific Reports
Kazuhiro Hanazaki, Masaya Munekage, Hiroyuki Kitagawa, Tomoaki Yatabe, Eri Munekage, Mai Shiga, Hiromichi Maeda, Tsutomu Namikawa
The incidence of diabetes is increasing at an unprecedented pace and has become a serious health concern worldwide during the last two decades. Despite this, adequate glycemic control using an artificial pancreas has not been established, although the 21st century has seen rapid developments in this area. Herein, we review current topics in glycemic control for both the wearable artificial pancreas for type 1 and type 2 diabetic patients and the bedside artificial pancreas for surgical diabetic patients. In type 1 diabetic patients, nocturnal hypoglycemia associated with insulin therapy remains a serious problem that could be addressed by the recent development of a wearable artificial pancreas...
September 2016: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
Caixia Xu, Jingwen Zhang, Yingyin K Zou, Hua Zhao
The enhancement of green upconverted emission from the Er<sup>3+</sup>/Yb<sup>3+</sup> co-doped (Pb,La)(Zr,Ti)O<sub>3</sub> ceramic powder under a pumping light with a wavelength of 1480 nm was observed to be greater than 30 times that from the bulk of the same sample. Weak localization of light supported by the spatial profile of scattered light facilitated the three-photon process contributing to stronger green upconverted emission. Significant backward light amplification was also observed and studied in detail...
March 21, 2016: Optics Express
Martin Cour, Thomas Bénet, Romain Hernu, Marie Simon, Thomas Baudry, Philippe Vanhems, Laurent Argaud
BACKGROUND: Changeovers of norepinephrine infusion pumps (CNIPs) frequently lead to haemodynamic instability. The aim of this study was to identify risk factors for haemodynamic instability associated with CNIP, independent of the method used to perform the relay. METHODS: We performed a prospective study, in a university-affiliated intensive care unit. Over a 1-year period, all adult patients who had at least one CNIP were included. CNIPs were automatically performed using smart pumps, in accordance with a standardised protocol...
December 2016: Annals of Intensive Care
Bryony Dean Franklin
No abstract text is available yet for this article.
April 7, 2016: BMJ Quality & Safety
Saad Abdel-Sayed, Ludwig-Karl von Segesser
Contribution of venovenous extracorporeal membrane oxygenation (v-v ECMO) to gas transfer is flow dependent. Catheter design is a key factor for optimal pressure/flow rate relationship. This study was designed for the assessment of a new self-expanding dual lumen catheter design versus the current standard. Outlet pressure/flow rate and inlet pressure/flow rate for a new Smart catheter with self-expanding dual lumen design constricted to 27 F with 5 mm long constrictor corresponding to the percutaneous path versus Avalon 27 F catheter (control) were compared on a flow bench with a Biomedicus centrifugal pump...
July 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
S Manrique-Rodríguez, A C Sánchez-Galindo, C M Fernández-Llamazares, M M Calvo-Calvo, Á Carrillo-Álvarez, M Sanjurjo-Sáez
OBJECTIVES: To estimate the impact of smart pump implementation in a pediatric intensive care unit in terms of number and type of administration errors intercepted. DESIGN: Observational, prospective study carried out from January 2010 to March 2015 with syringe and great volumen infusion pumps available in the hospital. SETTING: A tertiary level hospital pediatric intensive care unit. PARTICIPANTS: Infusions delivered with infusion pumps in all pediatric intensive care unit patients...
October 2016: Medicina Intensiva
Qi Zhang, Huiqiao Li, Lin Gan, Ying Ma, Dmitri Golberg, Tianyou Zhai
The widespread availability of nanostructures and nanodevices has placed strict requirements on their comprehensive characterization. Herein, in situ techniques are demonstrated to have created a rare opportunity to accurately analyze the intrinsic properties of individual nanostructures and to accomplish the smart design of nanodevices made from these nanostructures. This paper reviews recent developments in in situ fabrication and characterization technologies established within various types of microscopes and the rich information they may provide...
May 7, 2016: Chemical Society Reviews
Julie M McLaughlin, Brandi D Schimpf, Sylvia Park
PROBLEM: Although consensus exists among experts that early intravenous antibiotic therapy has an impact on patient mortality, the medical literature includes little information about ensuring that the patient receives the complete dose. At our emergency department, it had become standard clinical practice to administer antibiotics with primary pump tubing and an infusion pump. Clinical pharmacy staff identified this practice as a cause for concern, because at least 20 mL (up to 40%) of the dose volume remains in the tubing...
July 2016: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
Aamir Shahzad, Malrey Lee, Neal Naixue Xiong, Gisung Jeong, Young-Keun Lee, Jae-Young Choi, Abdul Wheed Mahesar, Iftikhar Ahmad
In Industrial systems, Supervisory control and data acquisition (SCADA) system, the pseudo-transport layer of the distributed network protocol (DNP3) performs the functions of the transport layer and network layer of the open systems interconnection (OSI) model. This study used a simulation design of water pumping system, in-which the network nodes are directly and wirelessly connected with sensors, and are monitored by the main controller, as part of the wireless SCADA system. This study also intends to focus on the security issues inherent in the pseudo-transport layer of the DNP3 protocol...
2016: Sensors
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