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https://www.readbyqxmd.com/read/29049632/an-engineering-model-to-test-for-sensory-reweighting-in-non-human-primate-posture
#1
Lara A Thompson, Csilla Haburcakova, Adam D Goodworth, Richard F Lewis
Quantitative animal models are critically needed to provide proof-of-concept for the investigation of rehabilitative balance therapies (e.g., invasive vestibular prostheses) and treatment response prior to, or in conjunction with, human clinical trials. This paper describes a novel approach to modeling the non-human primate postural control system. Our observation that rhesus macaques and humans have even remotely similar postural control motivates the further application of the rhesus macaque as a model for studying the effects of vestibular dysfunction, as well as vestibular prosthesis-assisted states, on human postural control...
October 10, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29048181/an-open-label-pilot-study-of-an-intervention-using-mobile-phones-to-deliver-contingency-management-of-tobacco-abstinence-to-high-school-students
#2
Grace Kong, Alissa L Goldberg, Jesse Dallery, Suchitra Krishnan-Sarin
This pilot study assessed the feasibility, acceptability, and preliminary efficacy of a smoking cessation intervention that used mobile phones to remotely deliver reinforcements contingent on tobacco abstinence (contingency management [CM]) and weekly in-person cognitive-behavioral therapy to adolescent smokers. Daily adolescent smokers (N = 15; 12 completed study procedures, 3 dropped out) were recruited to participate in a 4-week study. During the first 2 weeks, daily text messages sent at random times prompted participants to transmit a video of themselves providing a carbon monoxide (CO) sample...
October 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29044455/use-of-an-app-controlled-neuromuscular-electrical-stimulation-system-for-improved-self-management-of-knee-conditions-and-reduced-costs
#3
Morad Chughtai, Nicholas Piuzzi, George Yakubek, Anton Khlopas, Nipun Sodhi, Assem A Sultan, Salahuddin Nasir, Benjamin S T Yates, Anil Bhave, Michael A Mont
Patients suffering from quadriceps muscle weakness secondary to osteoarthritis or after surgeries, such as total knee arthroplasty, appear to benefit from the use of neuromuscular electrical stimulation (NMES), which can improve muscle strength and function, range of motion, exercise capacity, and quality of life. Several modalities exist that deliver this therapy. However, with the ever-increasing demand to improve clinical efficiency and costs, digitalize healthcare, optimize data collection, improve care coordination, and increase patient compliance and engagement, newer devices incorporating technologies that facilitate these demands are emerging...
October 12, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29041889/-multifactorial-prognostication-of-remote-outcomes-in-patients-with-non-st-elevation-acute-coronary-syndrome
#4
V O Tsygankova, G N Lozhkina, H M Khasanova, D A Kuimov, I Y Ragino, N V Maksimov, I M Voevoda
AIM: Creation of a mathematical nonlinear regression model for prognostication of 1 year outcomes after non-ST elevation acute coronary syndrome (NSTE ACS) for optimization of rehabilitation, secondary prevention, and personalized approach to treatment. MATERIAL AND METHODS: We included in this study 135 patients with confirmed NSTE ACS (mean age 59.1±6.1 years, 94 men and 41 women) admitted to hospital No 1 in Novosibirsk during 2010. During hospitalization and 1 year after discharge these patients received standard medical therapy...
August 2017: Kardiologiia
https://www.readbyqxmd.com/read/29036292/association-between-implantable-cardioverter-defibrillator-therapy-and-different-lead-positions-in-patients-with-cardiac-resynchronization-therapy
#5
Mads Brix Kronborg, Jens Brock Johansen, Jens Haarbo, Sam Riahi, Berit Thornvig Philbert, Ole Dan Jørgensen, Jens Cosedis Nielsen
Aims: To evaluate the impact of different right and left ventricular lead positions (RV-LP and LV-LP) on the risk of therapy for ventricular tachycardia/ventricular fibrillation in patients with a cardiac resynchronization therapy device (CRT-D). Methods and results: We performed a large nationwide cohort study on patients in Denmark receiving a CRT-D device from 2008 to 2012 from the Danish Pacemaker and implantable cardioverter defibrillator (ICD) registry. Lead positions were registered during the implantation and categorized as anterior/lateral/posterior and basal/mid-ventricular/apical for the LV-LP, and as apical/non-apical for the RV-LP...
September 27, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29034307/uterine-clostridium-perfringens-infection-related-to-gynecologic-malignancy
#6
Kevin M Kremer, Megan E McDonald, Michael J Goodheart
Uterine gas gangrene caused by Clostridium perfringens is a serious, often life-threatening infection that is rarely encountered in the practice of gynecologic oncology. However, the hypoxic nature of gynecologic cancers due to necrosis and/or prior radiation therapy creates a microenvironment optimal for proliferation of anaerobic bacteria such as the Clostridium species. Early recognition and aggressive treatment with IV antibiotics and surgical debridement remain the cornerstones of management in order to decrease morbidity and mortality...
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29027812/use-of-a-novel-remotely-connected-diabetes-management-system-is-associated-with-increased-treatment-satisfaction-reduced-diabetes-distress-and-improved-glycemic-control-in-individuals-with-insulin-treated-diabetes-first-results-from-the-personal-diabetes-management
#7
Pablo Mora, Ann Buskirk, Maureen Lyden, Christopher G Parkin, Lena Borsa, Bettina Petersen
BACKGROUND: The ability to automatically transfer data to clinicians and receive timely guidance in therapy adjustments through remote and in-office consults can positively impact patients' perceptions about quality of care, which is positively associated with clinical outcomes. We assessed the impact of using the Accu-Chek Connect diabetes management system on treatment satisfaction, diabetes distress, and glycemic control in adults with type 1 diabetes and insulin-treated type 2 diabetes...
October 13, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29024613/remote-monitoring-of-automated-peritoneal-dialysis-patients-assessing-clinical-and-economic-value
#8
Dilip Makhija, Mark Dominik Alscher, Stefan Becker, Silvia D'Alonzo, Raj Mehrotra, Leslie Wong, Kim McLeod, Judy Danek, Mary Gellens, Todd Kudelka, James A Sloand, Suzanne Laplante
BACKGROUND: For chronic kidney disease patients who progress to end-stage renal disease, survival is dependent on renal replacement therapy in the form of kidney transplantation or chronic dialysis. Peritoneal dialysis (PD), which can be performed at home, is both more convenient and less costly than hemodialysis that requires three 4-h visits per week to the dialysis facility and complicated equipment. Remote therapy management (RTM), technologies that collect medical information and transmit it to healthcare providers for patient management, has the potential to improve the outcomes of patients receiving automated peritoneal dialysis (APD) at home...
October 12, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28993117/getting-to-the-heart-of-the-matter-what-is-the-landscape-of-exercise-rehabilitation-for-people-with-heart-failure-in-australia
#9
Simon Miller, Allison Mandrusiak, Julie Adsett
BACKGROUND: The benefits of exercise rehabilitation for people with heart failure (HF) are well established. In Australia, little is known about how the guidelines around exercise rehabilitation for people with HF are being implemented in clinical practice. Furthermore, it is unknown what organisational barriers are faced in providing exercise rehabilitation programs for this population. The aim of this study is to provide an updated review of exercise rehabilitation services for people with HF in Australia and to identify perceived organisational barriers to providing these services...
September 25, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28990455/remote-consulting-with-telemonitoring-of-continuous-positive-airway-pressure-usage-data-for-the-routine-review-of-people-with-obstructive-sleep-apnoea-hypopnoea-syndrome-a-systematic-review
#10
Phyllis Murphie, Stuart Little, Brian McKinstry, Hilary Pinnock
Introduction Telehealth has the potential to offer more convenient care and reduce travel. We aimed to systematically review studies that assessed the effectiveness of teleconsultation plus telemonitoring in the review of people with obstructive sleep apnoea hypopnoea syndrome receiving continuous positive airway pressure therapy versus face-to-face care. Methods Following Cochrane methodology, we searched 10 electronic databases (November 2015), trial registries, and reference lists of included studies, for trials testing interventions that combined remote consultations with telemonitoring of usage/continuous positive airway pressure data...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28982501/pulmonary-artery-pressure-guided-management-of-patients-with-heart-failure-and-reduced-ejection-fraction
#11
RANDOMIZED CONTROLLED TRIAL
Michael M Givertz, Lynne W Stevenson, Maria R Costanzo, Robert C Bourge, Jordan G Bauman, Gregg Ginn, William T Abraham
BACKGROUND: Despite increased use of guideline-directed medical therapy (GDMT), some patients with heart failure and reduced ejection fraction (HFrEF) remain at high risk for hospitalization and mortality. Remote monitoring of pulmonary artery (PA) pressures provides clinicians with actionable information to help further optimize medications and improve outcomes. OBJECTIVES: CHAMPION (CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure Patients trial) analyzed PA pressure-guided heart failure (HF) management in patients with HFrEF based on their ability to tolerate GDMT...
October 10, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28971826/the-implementation-of-the-plan-esperanza-and-response-to-the-impact-review
#12
REVIEW
Tatiana Vidaurre, Carlos Santos, Henry Gómez, Gustavo Sarria, Edgar Amorin, Marga López, Roxana Regalado, Javier Manrique, Duniska Tarco, Carlos Ayestas, Mónica Calderón, Luis Mas, Silvia Neciosup, Miriam Salazar, Juan Carlos Chávez, Milward Ubillus, Abel Limache, José Carlos Ubillus, Jeannie Navarro, Kavita Sarwal, Simon Sutcliffe, Alfonso Gutiérrez-Aguado, Marianela Silva, Amalia Mena, María Eugenia Guillén, Carlos Castañeda, Julio Abugattas
Following the implementation of the National Cancer Prevention and Control Results-based Budget Programme (PpR Cancer-024) in 2011, the Peruvian Government approved the Plan Esperanza-a population-based national cancer control plan-in 2012. Legislation that ensured full government-supported funding for people who were otherwise unable to access or afford care and treatment accompanied the Plan. In 2013, the Ministry of Health requested an integrated mission of the Programme of Action for Cancer Therapy (imPACT) report to strengthen cancer control in Peru...
October 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28971063/nanoparticle-drones-to-target-lung-cancer-with-radiosensitizers-and-cannabinoids
#13
Wilfred Ngwa, Rajiv Kumar, Michele Moreau, Raymond Dabney, Allen Herman
Nanotechnology has opened up a new, previously unimaginable world in cancer diagnosis and therapy, leading to the emergence of cancer nanomedicine and nanoparticle-aided radiotherapy. Smart nanomaterials (nanoparticle drones) can now be constructed with capability to precisely target cancer cells and be remotely activated with radiation to emit micrometer-range missile-like electrons to destroy the tumor cells. These nanoparticle drones can also be programmed to deliver therapeutic payloads to tumor sites to achieve optimal therapeutic efficacy...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28970365/early-peritonitis-and-its-outcome-in-incident-peritoneal-dialysis-patients
#14
Emily J See, David W Johnson, Carmel M Hawley, Elaine M Pascoe, Darsy Darssan, Philip A Clayton, Monique Borlace, Sunil V Badve, Kamal Sud, Neil C Boudville, Yeoungjee Cho
BACKGROUND: Early-onset peritonitis is a serious complication of peritoneal dialysis (PD) and is associated with heightened risks of technique failure and death. The risk factors for early peritonitis and its outcomes are unknown. METHODS: This registry study examined all incident Australian PD patients between 2003 and 2014. The primary outcome was early peritonitis, defined as onset within 12 months of starting therapy. Secondary outcomes were medical cure, relapse/recurrence, catheter removal, peritonitis-associated technique failure, and peritonitis-associated death...
September 28, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28969980/ventricular-arrhythmia-occurrence-and-compliance-in-patients-treated-with-the-wearable-cardioverter-defibrillator-following-percutaneous-coronary-intervention
#15
Jérémie Barraud, Pauline Pinon, Marc Laine, Jennifer Cautela, Morgane Orabona, Linda Koutbi, Johan Pinto, Franck Thuny, Frederic Franceschi, Franck Paganelli, Laurent Bonello, Michaël Peyrol
BACKGROUND: The wearable cardioverter defibrillator (WCD) is a life-saving therapy in patients with high risk of arrhythmic death. We aimed to evaluate ventricular arrhythmia (VA) occurrence rate and compliance with the WCD during the first 90 days following myocardial revascularisation with percutaneous coronary intervention (PCI) in patients with left ventricular ejection fraction (LVEF) <30%. METHODS: From September 2015 to November 2016, clinical characteristics, WCD recordings and compliance data of the aforementioned subset of patients were prospectively collected...
September 25, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28968031/-effect-of-combined-application-of-ozone-therapy-and-gravitational-therapy-on-the-remote-results-of-complex-treatment-of-geriatric-patients
#16
I V Makarov, Yu V Shchukin, A V Lukashova
The article presents the remote results of treatment of an obliterating atherosclerosis of arteries of the lower extremities of the II stage at patients of advanced and senile age after the combined use of ozone therapy and gravitational therapy. We performed a prospective randomized study in three parallel groups (139 patients). The 1st group (n=57) received standard medical therapy in combination with ozone therapy; the group was divided into two subgroups: for patients of subgroup 1a (n=28) - intravenous ozonized physiological solution was performed, for patients of subgroup 1b (n=29) - major ozonized autohemotherapy...
2017: Advances in Gerontology, Uspekhi Gerontologii
https://www.readbyqxmd.com/read/28965980/remote-regulation-of-magnetic-particle-targeted-wnt-signaling-for-bone-tissue-engineering
#17
Michael Rotherham, James R Henstock, Omar Qutachi, Alicia J El Haj
Wnt signaling is critically involved in the differentiation of human Mesenchymal Stem Cells (hMSC). Wnt proteins therefore have considerable therapeutic value, but are expensive and difficult to produce. UM206 is a synthetic peptide and ligand for the Wnt receptor Frizzled. Attachment of UM206 to magnetic nanoparticles (MNP) enables the ligand-MNP complex to be manipulated using magnetic fields, allowing control of Frizzled stimulation. Using this approach, Wnt signaling was activated in hMSC which resulted in Frizzled clustering, β-catenin translocalization and activation of TCF/LEF responsive transcription...
September 29, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28959710/bilateral-control-of-functional-electrical-stimulation-and-robotics-based-telerehabilitation
#18
Naji Alibeji, Brad E Dicianno, Nitin Sharma
Currently a telerehabilitation system includes a therapist and a patient where the therapist interacts with the patient, typically via a verbal and visual communication, for assessment and supervision of rehabilitation interventions. This mechanism often fails to provide physical assistance, which is a modus operandi during physical therapy or occupational therapy. Incorporating an actuation modality such as functional electrical stimulation (FES) or a robot at the patient's end that can be controlled by a therapist remotely, to provide therapy or to assess and measure rehabilitation outcomes can significantly transform current telerehabilitation technology...
February 2017: International journal of intelligent robotics and applications
https://www.readbyqxmd.com/read/28958885/pathophysiology-screening-and-treatment-of-rop-a-multi-disciplinary-perspective
#19
REVIEW
Tailoi Chan-Ling, Glen A Gole, Graham E Quinn, Samuel J Adamson, Brian A Darlow
The population of infants at risk for retinopathy of prematurity (ROP) varies by world region; in countries with well developed neonatal intensive care services, the highest risk infants are those born at less than 28 weeks gestational age (GA) and less than 1 kg at birth, while, in regions where many aspects of neonatal intensive and ophthalmological care are not routinely available, more mature infants up to 2000 g at birth and 37 weeks GA are also at risk for severe ROP. Treatment options for both groups of patients include standard retinal laser photocoagulation or, more recently, intravitreal anti-VEGF drugs...
September 25, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28953045/perioperative-acute-kidney-injury-an-under-recognized-problem
#20
Melanie Meersch, Christoph Schmidt, Alexander Zarbock
The incidence of perioperative acute kidney injury (AKI) is more common than previously recognized, especially in high-risk patients undergoing higher risk procedures. The growing number of patients who develop perioperative AKI is related, in part, to the aging population and increase in the number of individuals with chronic comorbidities, particularly those with premorbid chronic kidney disease. Despite the acceptance of standardization in the definition of AKI, clinicians routinely underdiagnose it and fail to appreciate that it is associated with considerable morbidity and mortality...
August 4, 2017: Anesthesia and Analgesia
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