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https://www.readbyqxmd.com/read/28742406/the-efficacy-of-low-dose-tadalafil-in-patients-undergoing-hemodialysis-with-end-stage-renal-disease
#1
Mustafa Suat Bolat, İsmail Özer, Onder Cinar, Ekrem Akdeniz, Ramazan Aşcı
BACKGROUND: Erectile dysfunction (ED) is a disorder that is frequently observed in people with chronic kidney disease who undergo hemodialysis (HD). In the context of evidence-based medicine, we aimed to investigate the effect of low-dose tadalafil on sexual function in patients undergoing HD. METHODS: The medical records of 30 males (aged 29-65 years) with end-stage renal disease (ESRD) on a HD program, and who had received 5 mg tadalafil twice weekly, were retrospectively evaluated...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28736428/penile-doppler-ultrasonography-revisited
#2
Dae Chul Jung, Sung Yoon Park, Joo Yong Lee
Penile Doppler ultrasonography is a high-performing, noninvasive or minimally-invasive imaging modality that allows the depiction of the normal anatomy and macroscopic pathologic changes in real time. Moreover, functional changes in penile blood flow, as seen in erectile dysfunction (ED), can be analyzed using color Doppler ultrasonography (CDUS). This review article describes the normal sonographic anatomy of the penis, the sonographic technique for evaluating ED, the normal phases of erection, and the various causes of ED...
June 10, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28710184/diagnostic-value-of-four-dimensional-ct-angiography-in-arterial-erectile-dysfunction-using-320-detector-row-dynamic-volume-ct
#3
Cheng-Cheng Xu, Xin-Zhong Ruan, Yi-Fan Tang, Jiao-Hai Pan, Guo-Yao Wang, Qiu-Li Huang
The study aims to evaluate the diagnostic value of four-dimensional CT angiography (4D-CTA) in the diagnosis of arterial erectile dysfunction (ED) using 320-detector row dynamic volume CT. Arterial ED patients attributed to arterial insufficiency were enrolled. To induce penile erection, an intracavernous injection of corpus cavernosum with a vasoactive drug was administered. Patients were assigned into the erection hardness score (EHS) 1/2 group or EHS 3/4 group. Color duplex Doppler ultrasound (CDDU) was used to analyze blood flow spectrum...
July 14, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28703286/effect-of-quercetin-on-cadmium-chloride-induced-impairments-in-sexual-behaviour-and-steroidogenesis-in-male-wistar-rats
#4
G A Ujah, V U Nna, M I Agah, L O Omue, C B Leku, E E Osim
Cadmium chloride (CdCl2 ) has been reported to cause reproductive toxicity in male rats, mainly through oxidative stress. This study examined its effect on sexual behaviour, as one of the mechanisms of reproductive dysfunction, as well as the possible ameliorative effect of quercetin (QE) on same. Thirty male Wistar rats (10 weeks old), weighing 270-300 g, were used for this study. They were either orally administered 2% DMSO, CdCl2 (5 mg/kg b.w.), QE (20 mg/kg b.w.) or CdCl2 +QE, once daily for 4 weeks, before sexual behavioural studies...
July 13, 2017: Andrologia
https://www.readbyqxmd.com/read/28686363/-%C3%A2-doctor-i-have-a-little-erection-problem-%C3%A2
#5
Jean Dupraz, Julien Zumkehr, Grégoire Mayor
Erectile dysfunction (ED) is a common condition that affects nearly one in three men age 50 and more than one in two after 70 years. It is often multifactorial and shares risk factors with coronary heart disease, which is an early marker. Its management involves an etiological research, a modifiable risk factors correction and often a treatment with phosphodiesterase type 5 inhibitors (IPDE-5). Follow-up should ensure the effectiveness of treatment and the presence of side effects that could affect medication compliance...
September 28, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28679188/alprostadil-plus-vacuum-vitarum-in-severe-erectile-dysfunction-ed
#6
Franco Mantovani
OBJECTIVES: Severe erectile dysfunction (ED) is not uncommon, as can be seen from the epidemiological literature, and there are several possible causes, which are not always known, or leastways evident. Having ascertained the ineffectiveness, intolerance to or rejection of pharmacological aids, the option of prosthetic surgery remains, but before this, it may be wise when feasible to use Alprostadil cream in association with Vacuum device. MATERIAL AND METHODS: 12 patients, aged between 55 and 65 years, with severe erectile dysfunction without palpable cavernous fibrosis, were instructed to self-insert into the urethral meatus, 3 mg of Alprostadil cream, sufficient to make it easy to place the Vacuum device over the penis...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28656928/dynamic-and-morphologic-evaluation-of-erectile-dysfunction-on-penile-doppler-sonography-and-contrast-cavernosography
#7
A Ismail, A M Tabari, S U Alhasan, A Abdullahi
BACKGROUND: Penile erection is a complex phenomenon that involves coordinated interaction of the psychologic, hormonal, nervous, arterial, venous, and sinusoidal systems. Erectile dysfunction (ED) is the persistent inability to attain or maintain penile erection sufficient for sexual intercourse. This study aims to determine the real-time morphologic vascular abnormalities in men with ED using penile Doppler sonography in Kano, Nigeria. MATERIALS AND METHODS: Twenty-one patients who were referred from urology clinics on account of suspected vasculogenic ED were reviewed...
June 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28642047/erectile-dysfunction-in-young-men-a-review-of-the-prevalence-and-risk-factors
#8
REVIEW
Hoang Minh Tue Nguyen, Andrew T Gabrielson, Wayne J G Hellstrom
INTRODUCTION: Erectile dysfunction (ED) is an important health concern that can significantly affect a man's psychosocial well-being. ED has traditionally been considered a disease of old age; however, contemporary evidence suggests a growing incidence of ED in men younger than 40 years. The process of achieving an erection is multifaceted; there are many potential mechanisms that can be disrupted. It is critical to identify the specific causes of ED before proceeding with potentially costly and invasive therapeutic options...
June 19, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28632146/physiological-interrelationships-between-the-venous-shunts-of-penile-corpus-spongiosum-and-cavernous-compartments-during-erection-used-in-the-pharmacotherapy-of-erectile-dysfunction
#9
Fabio Pezzoni
AIM OF THE STUDY: Alprostadil (A) induces smooth-muscle relaxation by stimulating the increasing of intracellular cAMP. Intra-urethral administration is an alternative to its intra-cavernose injection in inducing erection. In order to understand the functional and anatomical basis for drug transfer, the possible communications of the corpus spongiosum with the corpora cavernosa were studied. MATERIAL OF STUDY: A "Spongiogram" (SP) was performed in 44patients (pt...
April 7, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28624321/does-any-association-exist-between-chronic-obstructive-pulmonary-disease-and-erectile-dysfunction-the-decoded-study
#10
M Dias, M J Oliveira, P Oliveira, I Ladeira, R Lima, M Guimarães
INTRODUCTION: Erectile dysfunction (ED) is the inability to achieve or maintain an erection for satisfactory sexual activity. Recent studies have shown an association between ED and chronic obstructive pulmonary disease (COPD). However, this issue is often ignored. We aimed to evaluate the ED prevalence in COPD patients and its risk factors and to study the impact of dyspnea in sexual activity. METHODS: Cross-sectional study that included sexually active male patients with COPD...
June 16, 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/28603514/cutaneous-autonomic-pilomotor-testing-to-unveil-the-role-of-neuropathy-progression-in-early-parkinson-s-disease-capture-pd-protocol-for-a-multicenter-study
#11
Timo Siepmann, Alexandra Pintér, Sylvia J Buchmann, Leonie Stibal, Martin Arndt, Anne Sophie Kubasch, Marie Luise Kubasch, Ana Isabel Penzlin, Elka Frenz, Wagner Zago, Tamás Horváth, Szabolcs Szatmári, Dániel Bereczki, Annamária Takáts, Tjalf Ziemssen, Axel Lipp, Roy Freeman, Heinz Reichmann, Kristian Barlinn, Ben Min-Woo Illigens
BACKGROUND: In Parkinson's disease (PD), alpha-synuclein accumulation in cutaneous autonomic pilomotor and sudomotor nerve fibers has been linked to autonomic nervous system disturbances even in the early stages of the disease. This study aims to assess the association between alpha-synuclein-mediated structural autonomic nerve fiber damage and function in PD, elucidate the role of neuropathy progression during the early disease stages, and test reproducibility and external validity of pilomotor function assessment using quantitative pilomotor axon-reflex test and sudomotor function via quantitative direct and indirect test of sudomotor function...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28603125/estimation-of-yohimbine-base-in-complex-mixtures-by-quantitative-hptlc-application
#12
Maged Saad Adel-Kader, Naif Wahebi Hamadan Alwahebi, Prawez Alam
The indole alkaloid Yohimbine has been used for over two centuries in the treatment of erectly dysfunction. Several formulations containing yohimbine salts, yohimbe bark power or extract are marketed worldwide. Determination of the amount of yohimbine in such formulation is a challenging task due to their complex nature. Extraction followed by acid-base purification resulted in a relatively pure alkaloids containing fractions. The exact amounts of yohimbine free base in different formulations were determined by densitometric HPTLC validated methods using silica gel TLC plates...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28595451/dependent-erythema-of-the-legs-associated-with-mild-autonomic-nervous-system-dysfunction
#13
Bahar Bahrani, Christopher S Sladden
INTRODUCTION: Dependent erythema or rubor is an erythematous discoloration of the limbs, most commonly associated with peripheral artery disease. We present a case of florid dependent erythema, associated with additional autonomic symptoms. METHODS: Examination and full workup of a 16-year-old healthy girl with an 8-year history of dependent erythema, chronic diarrhea, and mild hyperhidrosis. A literature search was performed to review any similar cases and generate a differential diagnosis...
June 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28593169/atherosclerosis-is-associated-with-erectile-function-and-lower-urinary-tract-symptoms-especially-nocturia-in-middle-aged-men
#14
Akira Tsujimura, Ippei Hiramatsu, Yusuke Aoki, Hirofumi Shimoyama, Taiki Mizuno, Taiji Nozaki, Masato Shirai, Kazuhiro Kobayashi, Yoshiaki Kumamoto, Shigeo Horie
BACKGROUND: Atherosclerosis is a systematic disease in which plaque builds up inside the arteries that can lead to serious problems related to quality of life (QOL). Lower urinary tract symptoms (LUTS), erectile dysfunction (ED), and late-onset hypogonadism (LOH) are highly prevalent in aging men and are significantly associated with a reduced QOL. However, few questionnaire-based studies have fully examined the relation between atherosclerosis and several urological symptoms. MATERIALS AND METHODS: The study comprised 303 outpatients who visited our clinic with symptoms of LOH...
June 2017: Prostate International
https://www.readbyqxmd.com/read/28584506/prognostic-factors-and-outcome-of-management-of-ischemic-priapism-in-zaria-nigeria
#15
Muhammed Ahmed, Benjamin Augustine, Messi Matthew, Mudi Awaisu, Abdullahi Sudi, Kolapo B Hamza, Ahmad Bello, Hussaini Yusuf Maitama
OBJECTIVES: The objective of this study was to determine the nuances of management, prognostic factors, and outcome of ischemic priapism in patients seen at Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. PATIENTS AND METHODS: We retrospectively studied the case notes of all patients managed for ischemic priapism in the Ahmadu Bello University Teaching Hospital, Zaria, over a period of 10 years (2006-2015). The data extracted included patients' age, occupation, duration of painful penile erection, and previous episodes...
January 2017: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/28583341/exploring-the-optimal-erectile-function-domain-score-cutoff-that-defines-sexual-satisfaction-after-radical-prostatectomy
#16
Jean E Terrier, John P Mulhall, Christian J Nelson
INTRODUCTION: The International Index of Erectile Function (IIEF) is the gold standard validated instrument for defining erectile function (EF) and its response to treatment. The EF domain (EFD) contains six questions and is a sensitive and specific measurement of treatment-related changes in EF. The EFD score has been widely used as a primary assessment end point for clinical trials of EF recovery after radical prostatectomy (RP). Various EFD scores have been used to define functional erections...
June 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28583339/off-label-use-of-phosphodiesterase-type-5-inhibitor-erectile-dysfunction-medication-to-enhance-sex-among-gay-and-bisexual-men-in-australia-results-from-the-flux-study
#17
Mohamed A Hammoud, Fengyi Jin, Toby Lea, Lisa Maher, Jeffrey Grierson, Garrett Prestage
BACKGROUND: Gay and bisexual men (GBM) use oral erectile dysfunction medications (EDMs) often with little evidence of medical indication necessitating their use. AIM: To investigate the prevalence, contexts, and motivations for oral EDM use and its relation to sexual risk behavior. METHODS: A total of 2,250 Australian GBM completed an online survey of licit and illicit drug use and their associated behaviors. Multivariate logistic regression analysis identified factors associated with use of EDMs in the previous 6 months and, for those who had used EDMs, factors associated with use on a weekly basis...
June 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28577498/telomerase-reverse-transcriptase-genetically-modified-adipose-tissue-derived-stem-cells-improves-erectile-dysfunction-by-inhibiting-oxidative-stress-and-enhancing-proliferation-in-rat-model
#18
Xiao-Jun Wu, Wen-Hao Shen, Peng He, Xiao-Zhou Zhou, Yi Zhi, Qiang Dai, Zhi-Wen Chen, Zhan-Song Zhou
Erectile dysfunction (ED) is considered to be incapable of obtaining or/and keeping a sufficient erection function to receive the satisfactory during the sexual intercourse. This study aims to investigate the effects of telomerase reverse transcriptase (hTERT) modified adipose tissue derived stem cells (ADSCs) autologously injected into cavernosa of the ED rats on erectile function. The ADSCs were isolated form the rat subcutaneous adipose tissue sample, and identified by examining the CD29 and CD44 molecule...
August 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28571949/low-energy-shock-wave-therapy-a-novel-treatment-option-for-erectile-dysfunction-in-men-with-cardiovascular-disease
#19
REVIEW
Dariusz Kalka, Jana Gebala, Ryszard Smoliński, Lesław Rusiecki, Witold Pilecki, Romuald Zdrojowy
Patients with cardiovascular disease (CVD) are prone to developing erectile dysfunction (ED) due to the common risk factors and pathogenesis underlying ED and CVD. As a result, ED affects nearly 80% of male patients with CVD. The efficacy of phosphodiesterase type 5 inhibitors, vacuum erection devices or intracavernosal injection of vasodilating agents is well established in the treatment of ED; however, their use is limited. Low energy shock-wave therapy (LESWT) is a novel modality that may become a causative treatment for ED...
May 29, 2017: Urology
https://www.readbyqxmd.com/read/28559803/aberrant-insula-centered-functional-connectivity-in-psychogenic-erectile-dysfunction-patients-a-resting-state-fmri-study
#20
Yue Wang, Minghao Dong, Min Guan, Jia Wu, Zhen He, Zhi Zou, Xin Chen, Dapeng Shi, Jimin Liang, Xiangsheng Zhang
Most previous studies exploring the neural mechanism of psychogenic erectile dysfunction (pED) focused on brain activity under tasks. We suggest that the resting brain activity is equally important in pED studies, in that the patterns of spontaneous neural activities is independent of modalities of sensory input, therefore providing substantial information regarding the central mechanism of pED. Our previous study reported the altered baseline activity in right anterior insula (aINS) in pED patients. Also, the insula is a pivotal region in sexual behavior, which is suggested to be able to directly mediate erection...
2017: Frontiers in Human Neuroscience
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