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https://www.readbyqxmd.com/read/29785045/an-initial-study-on-the-effect-of-functional-electrical-stimulation-in-erectile-dysfunction-a-randomized-controlled-trial
#1
Cristiane Carboni, Alexandre Fornari, Karoline C Bragante, Marcio A Averbeck, Patrícia Vianna da Rosa, Rodrigo Della Mea Plentz
Erectile dysfunction (ED) affects approximately 150 million men worldwide. Functional electrical stimulation (FES) therapy has shown a high regenerative capacity for smooth muscle cells and, therefore, is being increasingly adopted. FES can be a beneficial treatment option when the cause of ED is related to degeneration of cavernous smooth muscle. To evaluate the impact of FES on erectile function in men with erectile dysfunction. Twenty-two patients with ED participated in this randomized clinical trial. Participants were randomly assigned to two groups: intervention (IG) or control (CG)...
May 22, 2018: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29768277/the-brief-sexual-symptom-checklist-as-a-screening-tool-for-sex-related-problems-in-the-primary-care-setting-focus-on-erectile-dysfunction
#2
Javier Romero Otero, Borja García Gómez, José Medina Polo, Esther García Rojo, Eduardo García Cruz, Francois Peinado, Raquel Sopeña Sutil, Giorgio Bozzini, Alfredo Rodríguez Antolín
PURPOSE: To assess the performance of the Brief Sexual Symptom Checklist for men (BSSC-M) questionnaire in General Practitioner's (GP) consults in Spain. METHODS: Multicenter, cross-sectional study conducted in Spain among men ≥50 years, visiting a GP for any reason, and being able to answer self-administered questionnaires. Patients receiving medicines for erectile dysfunction (ED) and those with poor functional status were excluded. Sexual satisfaction was assessed by the BSSC-M, ED by the Sexual Health Inventory for Men (SHIM), and quality of life (QoL) using a 5-point Likert scale...
May 16, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29751956/relation-of-postexercise-reduction-of-arterial-blood-pressure-and-erectile-dysfunction-in-patients-with-coronary-heart-disease
#3
Dariusz Kałka, Jana Gebala, Lesław Rusiecki, Ryszard Smoliński, Jakub Dulanowski, Małgorzata Rusiecka, Anna Biełous-Wilk, Witold Pilecki, Krzysztof Womperski, Romuald Zdrojowy
Penile erection is a hemodynamic process consisting of 2 synchronized components in which the first (active) requires proper vascular endothelium functioning, whereas the second one (passive) is based on a veno-occlusive mechanism. Antihypertensive treatment reduces the passive component, often leading to the development of erectile dysfunction (ED), but lifestyle modifications can improve the sexual functioning. The study aimed to evaluate the association between blood pressure (BP) reduction caused by cardiovascular training and the intensity of ED in men with coronary heart disease...
April 18, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29745276/prevalence-and-characteristics-of-priapism-in-sickle-cell-disease
#4
Giovanna A O Arduini, Alessandra B Trovó de Marqui
Priapism is a pathological condition of persistent penile erection in the absence of sexual arousal or desire. It is an urological emergency and its identification is important as lack of prompt treatment can result in erectile dysfunction. The aim of this study was to estimate and describe the characteristics (number of episodes, duration, time of occurrence and evolution) of priapism in patients with sickle cell disease. A bibliographical research was carried out in PubMed, searching for papers published in the last 5 years...
May 10, 2018: Hemoglobin
https://www.readbyqxmd.com/read/29743519/transdermal-water-in-oil-nanocarriers-of-nitric-oxide-for-triggering-penile-erection
#5
Eunryel Nam, Saejong Yoo, Hwi-Yool Kim, Young-Rok Kim, Yun Jung Heo
Men's sexual health can have significant effects on a man's self-esteem, sexual relationship and male reproductive functions. Although commercially available drugs (e.g., VIAGRA and CIALIS) show effective treatment of erectile dysfunction (ED), patients with severe ED fail to respond to these medicines. Topical nitric-oxide (NO) delivery to penis can be a painless, alternative solution with severe ED because NO triggers erection and diffuses to the trabecular arteries and smooth muscles in the penis. We here develop water-in-oil (W/O) nanoemulsions (NEs) that contain NO and can directly spread on the penis...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29740301/impaired-prefrontal-amygdala-pathway-self-reported-emotion-and-erection-in-psychogenic-erectile-dysfunction-patients-with-normal-nocturnal-erection
#6
Jianhuai Chen, Yun Chen, Qingqiang Gao, Guotao Chen, Yutian Dai, Zhijian Yao, Qing Lu
Background: Neuroimaging studies have demonstrated that the prefrontal cortex and amygdala play an important role in sexual arousal (SA). However, little is known about the interactions between the prefrontal and cortex amygdala, which mediate the cognitive regulation of emotion and SA. Objective: We seek to determine whether nocturnal erection of psychogenic erectile dysfunction (pED) patients are normal and whether there are changes of topological organization in the prefrontal-amygdala pathway of brain network in pED...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29738168/-umbilicus-application-of-huobi-powder-for-ed-with-kidney-deficiency-dampness-a-randomized-controlled-clinical-trial
#7
Run-Biao Dong, Guang-Sen Li, De-Gui Chang, Jian Cai, Qu An
Objective: To prove the clinical efficacy of umbilicus application of Huobi Powder for the treatment of erectile dysfunction (ED) with the traditional Chinese medicine (TCM) syndrome of kidney deficiency dampness by related clinical indexes. METHODS: This randomized controlled double-blind clinical study included 72 ED patients with the TCM syndrome of kidney deficiency dampness treated by 12-hour application of Huobi Powder (the trial group, n = 36) or placebo (the control group, n = 36) to the umbilicus qd for 28 consecutive days...
November 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29736012/modified-16-dot-plication-technique-for-correction-of-penile-curvature-prevention-of-knot-related-complications
#8
Emad A Salem
Penile curvature is a common urological disease. Tunical plication for correction of penile curvature has been much popularized being simpler, adjustable to avoid overcorrection, less bleeding, and less postoperative erectile dysfunction. This study aims to assess the results of modified 16-dot plication technique for correction of congenital and acquired penile curvature and avoidance of knot-associated complications. Eighteen patients underwent correction of their penile curvature using the modified 16-dot plication technique between January 2014 and October 2015...
May 8, 2018: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29727543/-efficacy-and-safety-of-traditional-chinese-medicine-combined-with-sildenafil-in-the-treatment-of-ed-in-chinese-men%C3%AF-a-real-world-study
#9
Jun Guo, De-Gui Chang, Lei Chen, Bin Ou-Yang, Rui Zhang, Qiang Geng, Chao Yu, Fu Wang, Qing-He Gao, Guo-Jin Yu, Xiu-Ju Zhang
Objective: To make a real-world study on the efficacy and safety of traditional Chinese medicine (TCM) combined with sildenafil in the treatment of erectile dysfunction (ED) that failed to respond to TCM medication. METHODS: This study included 1 038 ED patients with the International Index of Erectile Function-5 (IIEF-5) scores ≤21 and improvement <30% after 4 weeks of TCM medication, differentially diagnosed with kidney-yang or kidney-yin deficiency syndrome...
October 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29726639/-value-of-non-sexual-penile-erection-for-penile-rehabilitation-in-men-with-erectile-dysfunction
#10
REVIEW
Bo-Dong Lü, Wen-Zhi Wang, Jun-Feng Yan, Gao-Yue Zhang
Erectile dysfunction (ED) is a common male disease. Some related studies show that the prevalence of ED is nearly 52% in men aged 40 to 70 years and is increasing among younger males. Hypoxia is now considered to be an independent risk factor for ED and the mechanisms of hypoxia inducing ED are varied and complicated. Recently, an idea in penile rehabilitation has attracted much attention, which aims at improving erectile function by increasing oxygen supply to the cavernosum and reducing tissue fibrosis and apoptosis...
August 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29723462/-prevention-and-treatment-of-erectile-dysfunction-after-prostatectomy-an-update
#11
REVIEW
Peng Xu, Yin-Huai Wang
Prostate cancer has the highest incidence among malignant tumors of the urinary system in China. Radical prostatectomy (RP) is the most effective treatment for localized prostate cancer with a good long-term prognosis. Erectile dysfunction (ED) is a common complication after RP, which seriously affects the patient's quality of life. With the rising incidence and early diagnosis of prostate cancer, the proportion of young cases of RP is increasing, and so is the importance of the treatment of post-RP ED. The restoration of erectile function after RP is closely related to the timing of penile rehabilitation as well as to pre- and intra-operative measures such as surgical strategies and methods...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29719326/prospective-study-to-evaluate-the-clinical-outcome-of-intralesional-interferon-%C3%AE-2b-in-the-management-of-peyronie-s-disease
#12
Ashok Kumar Sokhal, Nilesh Kumar Jain, Ankur Jhanwar, Kawaljit Singh, Durgesh Kumar Saini
Context: Interferon (IFN)-α2b in Peyronie's disease (PD). Aims: This study aims to evaluate clinical efficacy of the IFN-α2b in both subjective and objective manner for the treatment of PD and compared with previously used intralesional verapamil in terms of cost-benefit analysis. Settings and Design: Prospective study. Materials and Methods: A prospective study conducted from January 2013 to July 2016 in the Department of Urology, Government Medical College, Kota, Rajasthan, India...
April 2018: Urology Annals
https://www.readbyqxmd.com/read/29713098/successful-management-of-psychotropics-induced-stuttering-priapism-with-pseudoephedrine-in-a-patient-with-schizophrenia
#13
Srinagesh Mannekote Thippaiah, Soumya Nagaraja, Badari Birur, Ananda Pandurangi
Stuttering Priapism is a recurrent, persistent penile erection in the absence of sexual desire due to altered genital hemodynamics, affecting the arterial component (high flow, non-ischemic) or the veno-occlusive mechanism (low flow, ischemic). Both typical and atypical antipsychotics increase the risk for priapism with greater implications in typicals than atypicals. Prompt recognition and treatment are important as 40% to 50% of patients with stuttering priapism may develop an erectile dysfunction if left untreated...
February 5, 2018: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/29699756/predictive-factors-of-patients-and-their-partners-sexual-function-improvement-after-collagenase-clostridium-histolyticum-injection-for-peyronie-s-disease-results-from-a-multi-center-single-arm-study
#14
Andrea Cocci, Giorgio Ivan Russo, Andrea Salonia, Gianmartin Cito, Federica Regis, Gaia Polloni, Gianluca Giubilei, Giovanni Cacciamani, Marco Capece, Marco Falcone, Isabella Greco, Massimiliano Timpano, Andrea Minervini, Mauro Gacci, Tommaso Cai, Giulio Garaffa, Bruno Giammusso, Davide Arcaniolo, Vincenzo Mirone, Nicola Mondaini
BACKGROUND: Collagenase Clostridium histolyticum (CCH; Xiapex) injections represent the only licensed medical treatment for Peyronie's disease (PD). AIM: To evaluate the efficacy and safety of CCH injections in men with stable PD, using a modified treatment protocol and to assess partners' bother improvement in a large cohort of White-European sexually active heterosexual men treated in a single tertiary-referral center. METHODS: All the 135 patients enrolled underwent a thorough assessment, which included history taking, physical examination, and pharmacologically induced artificial erection test (intra-cavernous injection) to assess the degree of penile curvature (PC) at baseline and after the completion of the treatment...
May 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29687468/spontaneous-detumescence-and-full-restoration-of-erection-in-a-patient-with-high-flow-priapism-with-persistent-arterial-lacunar-fistula-after-repeated-selective-embolisation-a-case-report
#15
M Čechová, R Pádr, P Hanek, M Chocholatý
High-flow priapism is a rare condition mainly caused by perineal trauma. Laceration of cavernosal artery results in a formation of arterial-lacunar fistula with unregulated blood flow causing prolonged erection. We present a case of a 25-year-old man with high-flow priapism and concurrent erectile dysfunction treated with repeated selective embolisation with only a partial effect. When no further embolisation was possible, we assumed on conservative management even through the fistula was still present. Spontaneous detumescence occurred 9 months, and erectile function has fully restored 24 months after the injury...
April 23, 2018: Andrologia
https://www.readbyqxmd.com/read/29681053/diagnostic-value-of-plasma-pentraxin3-level-for-diagnosis-of-erectile-dysfunction
#16
Ali Erhan Eren, Ahmet Resit Ersay, Emrah Demirci, Cabir Alan, Gökhan Basturk
PURPOSE: Erectile dysfunction (ED) is a sexual dysfunction described as the inability to develop or maintain an erection of the penis adequate for sexual intercourse, and its prevalence increases with age. Seen as a common sexual disorder worldwide, organic causes are the underlying reason for 80 percent of ED cases, with the most characteristic pathology responsible for organic ED being atherosclerosis. This study investigates the diagnostic value of plasma PTX-3 levels in arterial ED...
April 19, 2018: Urology Journal
https://www.readbyqxmd.com/read/29675596/post-finasteride-syndrome-and-post-ssri-sexual-dysfunction-two-sides-of-the-same-coin
#17
REVIEW
Silvia Giatti, Silvia Diviccaro, Giancarlo Panzica, Roberto Cosimo Melcangi
Sexual dysfunction is a clinical condition due to different causes including the iatrogenic origin. For instance, it is well known that sexual dysfunction may occur in patients treated with antidepressants like selective serotonin reuptake inhibitors (SSRI). A similar side effect has been also reported during treatment with finasteride, an inhibitor of the enzyme 5alpha-reductase, for androgenetic alopecia. Interestingly, sexual dysfunction persists in both cases after drug discontinuation. These conditions have been named post-SSRI sexual dysfunction (PSSD) and post-finasteride syndrome (PFS)...
April 19, 2018: Endocrine
https://www.readbyqxmd.com/read/29667617/combination-of-stromal-vascular-fraction-and-ad-comp-ang1-gene-therapy-improves-long-term-therapeutic-efficacy-for-diabetes-induced-erectile-dysfunction
#18
Guo-Nan Yin, Lin Wang, Xiang-Nan Lin, Lei Shi, Zhen-Lin Gao, Feng-Chan Han, Ping Li, Yin-Chuan Jin, Jun-Kyu Suh, Ji-Kan Ryu, Xiong Wang, Hai-Rong Jin
Men with diabetic erectile dysfunction (ED) respond poorly to the currently available oral phosphodiesterase-5 inhibitors. Therefore, functional therapies for diabetic ED are needed. Stromal vascular fraction (SVF) and the adenovirus-mediated cartilage oligomeric matrix angiopoietin-1 (Ad-COMP-Ang1) gene are known to play critical roles in penile erection. We previously reported that SVF and Ad-COMP-Ang1 have only a short-term effect in restoring erectile function. Further improvements to ED therapy are needed for long-lasting effects...
April 17, 2018: Asian Journal of Andrology
https://www.readbyqxmd.com/read/29616224/the-relevance-of-sexual-dysfunction-related-to-groin-pain-after-inguinal-hernia-repair-the-sexihq-short-form-questionnaire-assessment
#19
Nihad Gutlic, Ulf Petersson, Peder Rogmark, Agneta Montgomery
Background: Chronic postoperative pain after inguinal hernia surgery can affect sexual function. A new short form questionnaire for inguinal hernia pain related sexual dysfunction (SexIHQ) was introduced and applied to a register based cohort of total extra-peritoneal hernioplasty (TEP) operated patients. Methods: Sexually active men, 30-60 years old, recorded in the Swedish Hernia Register for a primary inguinal hernia TEP operation were included. Two initial questions of the SexIHQ identify patients with pain at sexual activity...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29559788/the-relationship-between-hydration-status-male-sexual-dysfunction-and-depression-in-hemodialysis-patients
#20
Kamal Hassan, Yotam Elimeleh, Mona Shehadeh, Hassan Fadi, Irina Rubinchik
Background: Disturbances in sexual function are common among dialysis patients. Normal erections require a complex balance of physiological, psychological, emotional, hormonal, neurological and vascular factors. This study examined a possible association of overhydration (OH) with male sexual dysfunction and depression in hemodialysis (HD) patients. Patients and methods: This cross-sectional study assessed hydration status by whole-body bioimpedance spectroscopy in patients on maintenance HD for more than 12 months...
2018: Therapeutics and Clinical Risk Management
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