Katsunori Takagi, Keitaro Matsumoto, Daisuke Taniguchi, Ryusuke Machino, Fumitake Uchida, Ryosuke Hara, Kaido Oishi, Yusuke Yamane, Mayumi Iwatake, Masamichi Eguchi, Yasushi Mochizuki, Koichi Nakayama, Takeshi Nagayasu
Ureteral strictures, which can be caused by ureteral injury, radiation therapy, ureterolithiasis, urinary tract infections, and ureteral endometriosis, typically require ureteral reconstruction. Although tissue engineering, autologous alternative tissue transplantation, and surgical techniques applying various flaps have been carried out for ureteral regeneration, all with some success, each method has its advantages and disadvantages. As an alternative, we created the first artificial ureter structures using only live cells and grafted them into healthy rat ureters...
October 12, 2022: Acta Biomaterialia