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https://www.readbyqxmd.com/read/28816554/vaginal-axis-on-mri-after-unilateral-and-bilateral-sacral-hysteropexy-a-controlled-study
#1
Mehmet B Senturk, Cetin Kilicci, Sibel Aydin, Mesut Polat, Cigdem Abide Yayla, Ates Karateke
The objective of this study was to evaluate the vaginal position on magnetic resonance imaging (MRI) after bilateral abdominal sacral hysteropexy (BASH) and classical abdominal sacral hysteropexy (ASH) and to investigate which method keeps the vagina the most proximate to its original anatomical position. Ten patients, with 10 having BASH, 10 ASH and 10 being nulliparous, were compared. The angle between the vagina and the pubococcygeal plate, the angle between the upper and lower vaginal segments, the distance between the posterior fornix and the 2nd vertebra and the distances between the lateral fornices and spina ischiadica were measured on MRI...
August 17, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28807777/bilateral-temporal-myofascial-flap-for-the-reconstruction-of-frontal-sinus-defects
#2
Filippo Gagliardi, Michele Bailo, Alfio Spina, Nicola Boari, Carmine A Donofrio, Martina Piloni, Cristian Gragnaniello, Anthony J Caputy, Pietro Mortini
BACKGROUND: A frontal sinus infection, following a trans-sinus skull base procedure, portends potentially life-threatening complications, making surgical revision mandatory in refractory infections. The authors describe the application of the bilateral temporal myofascial flap (BTMF) as a valuable option for frontal sinus reconstruction, when pericranial or galeal-frontalis myofascial flap (GFMF) is no longer available. METHODS: A microanatomical laboratory investigation on cadaver was conducted to obtain anthropometric measurements...
August 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28804634/muscle-mri-findings-in-a-one-year-old-girl-with-merosin-deficient-congenital-muscular-dystrophy-type-1a-due-to-lama2-mutation-a-case-report
#3
Yingyin Liang, Guidian Li, Songlin Chen, Rongxing He, Xiangxue Zhou, Yingming Chen, Xue Xu, Ronglan Zhu, Cheng Zhang
The objective of the present study was to characterize the muscle magnetic resonance imaging (MRI) features of a 1-year-old girl with merosin-deficient congenital muscular dystrophy type 1A (MDC1A). Beginning as an infant, this patient exhibited severe hypotonia and proximal weakness, as well as delays in developmental milestones. Her serum creatine kinase levels at 3 months, 8 months and 1 year were 2,959, 1,621 and 1,659 U/l, respectively. Brain MRI indicated symmetric, mild T1WI low, mild T2WI and FLAIR high radial patterns in the white matter of the Cornu posterius of the ventricular lateral...
August 2017: Biomedical Reports
https://www.readbyqxmd.com/read/28799514/potentially-clinically-relevant-pharmacodynamic-interactions-between-antiepileptic-drugs-and-psychotropic-drugs-an-update
#4
Edoardo Spina, Jose de Leon
BACKGROUND: Prior articles paid little attention to pharmacodynamic drug interactions (DIs) between antiepileptic drugs (AEDs) and the most important psychotropic medications (antidepressants, antipsychotics, benzodiazepines and lithium) which have potential to be clinically relevant. OBJECTIVE: This article aims to provide an updated review of the potentially clinically relevant pharmacodynamic DIs between AEDs and psychotropic medications. Pharmacodynamic DIs take place directly at the site of action of a drug or indirectly by interfering with another physiological mechanism...
August 9, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28792793/effect-of-cricoarytenoid-joint-preservation-and-suture-tension-on-arytenoid-lateralization
#5
Elizabeth Davis, Brenda Salinardi, Jason Spina, Claire Sharp
The objective of this experimental study was to evaluate the effects of cricoarytenoid (CA) joint preservation versus disarticulation on rima glottidis (RG) area with the epiglottis open and closed under both low and high suture tension. Canine cadaver larynges were used. A unilateral arytenoid lateralization (UAL) was performed with low or high suture tension and with the CA joint preserved or disarticulated. Rima glottidis area was measured with the epiglottis in an open and closed position. Results indicated that RG area was increased over baseline when UAL was performed with both low and high suture tension when the epiglottis was in an open position...
August 9, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28776749/psychosocial-functioning-self-image-and-quality-of-life-in-children-and-adolescents-with-neurofibromatosis-type-1
#6
S Cipolletta, G Spina, A Spoto
BACKGROUND: Neurofibromatosis type 1 (NF1) is a genetic disorder associated with neurocutaneus manifestations, as well as attention and learning problems. The aim of this study was to examine the psychosocial functioning, quality of life, and self-image of children with NF1. METHOD: Two hundred forty participants were recruited, comprising 60 children and adolescents with NF1, 60 parents of children with NF1, 60 children and adolescents without NF1, and 60 parents of children without NF1...
August 3, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28775121/italian-real-life-experience-with-brentuximab-vedotin-results-of-a-large-observational-study-on-40-relapsed-refractory-systemic-anaplastic-large-cell-lymphoma
#7
Alessandro Broccoli, Cinzia Pellegrini, Alice Di Rocco, Benedetta Puccini, Caterina Patti, Guido Gini, Donato Mannina, Monica Tani, Chiara Rusconi, Alessandra Romano, Anna Vanazzi, Barbara Botto, Carmelo Carlo-Stella, Stefan Hohaus, Pellegrino Musto, Patrizio Mazza, Stefano Molica, Paolo Corradini, Angelo Fama, Francesco Gaudio, Michele Merli, Angela Gravetti, Giuseppe Gritti, Annalisa Arcari, Patrizia Tosi, Anna Marina Liberati, Antonello Pinto, Vincenzo Pavone, Filippo Gherlinzoni, Virginia Naso, Stefano Volpetti, Livio Trentin, Maria Cecilia Goldaniga, Maurizio Bonfichi, Amalia De Renzo, Corrado Schiavotto, Michele Spina, Sergio Storti, Angelo Michele Carella, Vittorio Stefoni, Lisa Argnani, Pier Luigi Zinzani
From November 2012 to July 2014, brentuximab vedotin was available in Italy for patients with relapsed systemic anaplastic large cell lymphoma outside a clinical trial context according to the national law 648/96. A large Italian observational retrospective study was conducted on the use of brentuximab vedotin in the everyday clinical practice to check if clinical trial results are confirmed even in a real life context. Primary endpoint was the best response; secondary endpoints were the overall response rate at the end of the treatment, duration of response, survival and the safety profile...
August 3, 2017: Haematologica
https://www.readbyqxmd.com/read/28774199/physical-activity-patterns-and-clusters-in-1001-patients-with-copd
#8
Rafael Mesquita, Gabriele Spina, Fabio Pitta, David Donaire-Gonzalez, Brenda M Deering, Mehul S Patel, Katy E Mitchell, Jennifer Alison, Arnoldus Jr van Gestel, Stefanie Zogg, Philippe Gagnon, Beatriz Abascal-Bolado, Barbara Vagaggini, Judith Garcia-Aymerich, Sue C Jenkins, Elisabeth Apm Romme, Samantha Sc Kon, Paul S Albert, Benjamin Waschki, Dinesh Shrikrishna, Sally J Singh, Nicholas S Hopkinson, David Miedinger, Roberto P Benzo, François Maltais, Pierluigi Paggiaro, Zoe J McKeough, Michael I Polkey, Kylie Hill, William D-C Man, Christian F Clarenbach, Nidia A Hernandes, Daniela Savi, Sally Wootton, Karina C Furlanetto, Li W Cindy Ng, Anouk W Vaes, Christine Jenkins, Peter R Eastwood, Diana Jarreta, Anne Kirsten, Dina Brooks, David R Hillman, Thaís Sant'Anna, Kenneth Meijer, Selina Dürr, Erica Pa Rutten, Malcolm Kohler, Vanessa S Probst, Ruth Tal-Singer, Esther Garcia Gil, Albertus C den Brinker, Jörg D Leuppi, Peter Ma Calverley, Frank Wjm Smeenk, Richard W Costello, Marco Gramm, Roger Goldstein, Miriam Tj Groenen, Helgo Magnussen, Emiel Fm Wouters, Richard L ZuWallack, Oliver Amft, Henrik Watz, Martijn A Spruit
We described physical activity measures and hourly patterns in patients with chronic obstructive pulmonary disease (COPD) after stratification for generic and COPD-specific characteristics and, based on multiple physical activity measures, we identified clusters of patients. In total, 1001 patients with COPD (65% men; age, 67 years; forced expiratory volume in the first second [FEV1], 49% predicted) were studied cross-sectionally. Demographics, anthropometrics, lung function and clinical data were assessed...
August 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28770373/early-predictive-factors-of-disability-in-cidp
#9
Emanuele Spina, Antonietta Topa, Rosa Iodice, Stefano Tozza, Lucia Ruggiero, Raffaele Dubbioso, Marcello Esposito, Dario Bruzzese, Lucio Santoro, Fiore Manganelli
The objective of this study was to identify early clinical, biochemical and electrophysiological prognostic factors of disability in CIDP. We evaluated a dataset from 60 CIDP patients that included sex, age of onset, type of onset, phenotype, disease duration, response to treatment, disability at the time of diagnosis assessed using the modified Rankin Scale (baseline mRS), cerebrospinal fluid protein levels and electrophysiological data. All patients had clinical assessment of disability through the mRS within the last 6 months (last mRS) before enrollment in the study...
August 2, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28768757/optimized-screening-of-coronary-artery-disease-with-invasive-coronary-angiography-and-ad-hoc-percutaneous-coronary-intervention-during-transcatheter-aortic-valve-replacement
#10
Marco Barbanti, Denise Todaro, Giuliano Costa, Gerlando Pilato, Andrea Picci, Simona Gulino, Piera Capranzano, Ketty La Spina, Emanuela Di Simone, Paolo D'Arrigo, Wanda Deste, Antonino Indelicato, Stefano Cannata, Daniela Giannazzo, Sebastiano Immè, Claudia Tamburino, Martina Patanè, Sergio Buccheri, Davide Capodanno, Carmelo Sgroi, Corrado Tamburino
BACKGROUND: We sought to describe an optimized approach to coronary artery disease (CAD) screening and management in patients undergoing transcatheter aortic valve replacement (TAVR). METHODS AND RESULTS: When invasive coronary angiography showed CAD, the treatment strategy and completeness of revascularization was determined based on coronary anatomy. TAVR was performed in the same setting if percutaneous coronary intervention (PCI) was uncomplicated; otherwise TAVR was postponed...
August 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28765064/treatment-of-epilepsy-in-patients-with-myasthenia-gravis-is-really-harder-than-it-looks
#11
Paulo José Lorenzoni, Renata Dal-Prá Ducci, Tallulah Spina Tensini, Giuliano Dalledone, Claudia Suemi Kamoi Kay, Luciano de Paola, Lineu Cesar Werneck, Rosana Herminia Scola, Carlos Silvado
The relationship between myasthenia gravis (MG) and epilepsy has been rarely reported. As consequence, there are no specific guidelines for the management of these conditions when they mutually occur. We reported on three patients in whom epilepsy and MG are coexisting, but in different clinical settings. Two patients were treated with antiepileptic drugs which improved their symptoms. One patient has controlled the seizures after a successful anterior temporal lobectomy with no appreciable consequences to her MG...
July 29, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28762464/the-mid-point-transverse-process-to-pleura-mtp-block-a-new-end-point-for-thoracic-paravertebral-block
#12
I Costache, L de Neumann, C J Ramnanan, S L Goodwin, A Pawa, F W Abdallah, C J L McCartney
Current descriptions of thoracic paravertebral block techniques require the needle tip to be anterior to the superior costotransverse ligament. We hypothesised that an injection point midway between the posterior border of the transverse process and the pleura would result in spread to the paravertebral space. We completed bilateral injections of 5 ml methylene blue 0.2% midway between the posterior border of the transverse process and the pleura at T2, T4, T6, T8 and T10 in three unembalmed cadavers. The presence of methylene blue dye at the nerve root in the paravertebral space, the corresponding intercostal nerve and sympathetic chain at the level of injection, and at additional levels, was examined...
August 1, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28761914/kinematic-and-emg-data-during-underwater-dolphin-kick-change-while-synchronizing-with-or-without-synchronization-of-kick-frequency-with-the-beat-of-a-metronome
#13
Keisuke Kobayashi Yamakawa, Hirofumi Shimojo, Hideki Takagi, Shozo Tsubakimoto, Yasuo Sengoku
We investigated the effects of synchronizing kick frequency with the beat of a metronome on kinematic and electromyographic (EMG) parameters during the underwater dolphin kick as a pilot study related to the research that entitled "Effect of increased kick frequency on propelling efficiency and muscular co-activation during underwater dolphin kick" (Yamakawa et al., 2017) [1]. Seven collegiate female swimmers participated in this experiment. The participants conducted two underwater dolphin kick trials: swimming freely at maximum effort, and swimming while synchronizing the kick frequency of maximum effort with the beat of a metronome...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28756299/is-the-size-and-composition-of-the-paraspinal-muscles-associated-with-low-back-pain-a-systematic-review
#14
REVIEW
Tom A Ranger, Flavia M Cicuttini, Tue Secher Jensen, Waruna L Peiris, Sultana Monira Hussain, Jessica Fairley, Donna M Urquhart
Background Context Although previous studies have investigated the association between paraspinal muscle morphology and low back pain (LBP), the results are conflicting. Purpose This systematic review examined the relationship between size and composition of the paraspinal muscles and LBP. Study design/ setting: Systematic review Patient sample: N/A Outcome measures: N/A Methods A systematic search of electronic databases was conducted to identify studies investigating the association between the cross-sectional area and/or fatty infiltration of the paraspinal muscles (erector spinae, multifidus, psoas and quadratus lumborum) and LBP...
July 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28751560/mutational-status-of-ighv-is-the-most-reliable-prognostic-marker-in-trisomy-12-chronic-lymphocytic-leukemia
#15
Pietro Bulian, Riccardo Bomben, Michele Dal Bo, Antonella Zucchetto, Francesca Maria Rossi, Massimo Degan, Federico Pozzo, Tamara Bittolo, Vanessa Bravin, Tiziana D'Agaro, Michaela Cerri, Annalisa Chiarenza, Kari G Chaffee, Adalgisa Condoluci, Giovanni D'Arena, Michele Spina, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, Davide Rossi, Giovanni Del Poeta, Gianluca Gaidano, Tait D Shanafelt, Valter Gattei
No abstract text is available yet for this article.
July 27, 2017: Haematologica
https://www.readbyqxmd.com/read/28750541/influence-of-different-cleaning-processes-on-the-surface-chemistry-of-gold-nanoparticles
#16
Rita La Spina, Valentina Spampinato, Douglas Gilliland, Isaac Ojea-Jimenez, Giacomo Ceccone
In this paper, the authors have investigated the effects of different cleaning methods (centrifugation and dialysis) on the surface chemistry and composition of 15 nm sodium citrate stabilized gold nanoparticles. The nuclear magnetic resonance (NMR) results indicate that three centrifugation cycles are sufficient to remove most of the citrate molecules, while centrifuged liquid sedimentation and dynamic light scattering data reveal some degree of nanoparticle aggregation when three centrifugation cycles are exceeded...
July 27, 2017: Biointerphases
https://www.readbyqxmd.com/read/28748328/potential-therapeutic-use-of-il-37-a-key-suppressor-of-innate-immunity-and-allergic-immune-responses-mediated-by-mast-cells
#17
REVIEW
Pio Conti, Francesco Carinci, Gianfranco Lessiani, Enrico Spinas, Spyridon K Kritas, Gianpaolo Ronconi, Alessandro Caraffa, Theoharis C Theoharides
The host response to either exogenous or endogenous insults produces a series of changes, characterized by alterations in immunological functions and generation of mediators called cytokines which include the interleukin-1 (IL-1) family members. IL-1 acts as a hormone mediating the host responses to infection and inflammation. Blocking inflammatory IL-1 family members can be effective against inflammatory disorders, including allergies. IL-37, (formerly IL-1 family member 7), emerges as an inhibitor of innate and adaptive immunity by reducing circulating and organ cytokine levels...
July 26, 2017: Immunologic Research
https://www.readbyqxmd.com/read/28748271/the-emerging-role-of-gamma-knife-radiosurgery-in-the-management-of-glossopharyngeal-neuralgia
#18
REVIEW
Alfio Spina, Nicola Boari, Filippo Gagliardi, Michele Bailo, Carlotta Morselli, Sandro Iannaccone, Pietro Mortini
Glossopharyngeal neuralgia (GPN) represents a rare craniofacial disorder accounting for about 1% of all craniofacial pain syndromes. GPN shares several pathophysiologic and clinical features with the more common trigeminal neuralgia. Medical therapy and microvascular decompression, in case of vascular nerve compression, represented the mainstay of GPN management. Other ablative therapies have been reported to date; however, few data are available because of the rarity of this pain syndrome. Among the ablative procedures, gamma knife radiosurgery (GKRS) has been recently introduced in the management of GPN with good pain control and low complication rates...
July 26, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28746947/-eccentric-training-after-a-traumatic-apophysis-fracture-at%C3%A2-the-spina-iliaca-anterior-inferior-case-study-of-a-junior-football-player
#19
Yvonne Landkammer, Florian Rieder, Robert Sassmann, Jürgen Herfert, Anton Wicker
Eccentric training is an established training method in competitive sports. It has been used effectively to improve muscle strength during rehabilitation after cruciate ligament reconstruction. However, it is still uncertain whether or not eccentric training contributes to successful rehabilitation after apophysis fractures. A fourteen-year-old soccer player, forward position, presents with an apophysis avulsion located at the right spina iliaca anterior inferior. After completing an early rehabilitation phase and isokinetic concentric strength development, the patient starts an eccentric training programme eight weeks after the injury, including training on an isokinetic dynamometer (Biodex) for four weeks, followed by a four-week eccentric ergometer training (Eccentron)...
July 26, 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/28743246/associations-between-national-viral-hepatitis-policies-programmes-and-country-level-socioeconomic-factors-a-sub-analysis-of-data-from-the-2013-who-viral-hepatitis-policy-report
#20
Jeffrey V Lazarus, Ida Sperle, Kelly Safreed-Harmon, Charles Gore, Beatriz Cebolla, Alexander Spina
BACKGROUND: As more countries worldwide develop national viral hepatitis strategies, it is important to ask whether context-specific factors affect their decision-making. This study aimed to determine whether country-level socioeconomic factors are associated with viral hepatitis programmes and policy responses across WHO Member States (MS). METHODS: WHO MS focal points completed a questionnaire on national viral hepatitis policies. This secondary analysis of data reported in the 2013 Global Policy Report on the Prevention and Control of Viral Hepatitis in WHO Member States used logistic regression to examine associations between four survey questions and four socioeconomic factors: country income level, Human Development Index (HDI), health expenditure and physician density...
July 26, 2017: BMC Public Health
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