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https://www.readbyqxmd.com/read/29214488/electron-microscopic-observations-of-prokaryotic-surface-appendages
#1
REVIEW
Ki Woo Kim
Prokaryotic microbes possess a variety of appendages on their cell surfaces. The most commonly known surface appendages of bacteria include flagella, pili, curli, and spinae. Although archaea have archaella (archaeal flagella) and various types of pili that resemble those in bacteria, cannulae, and hami are unique to archaea. Typically involved in cell motility, flagella, the thickest appendages, are 20-26 nm and 10-14 nm wide in bacteria and archaea, respectively. Bacterial and archaeal pili are distinguished by their thin, short, hair-like structures...
December 2017: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/29207679/italian-real-life-experience-with-brentuximab-vedotin-results-of-a-large-observational-study-on-234-relapsed-refractory-hodgkin-s-lymphoma
#2
Cinzia Pellegrini, Alessandro Broccoli, Alessandro Pulsoni, Luigi Rigacci, Caterina Patti, Guido Gini, Donato Mannina, Monica Tani, Chiara Rusconi, Alessandra Romano, Anna Vanazzi, Barbara Botto, Armando Santoro, Stefan Hoaus, Gian Matteo Rigolin, Pellegrino Musto, Patrizio Mazza, Stefano Molica, Paolo Corradini, Angelo Fama, Francesco Gaudio, Michele Merli, Fioravante Ronconi, Giuseppe Gritti, Daniele Vallisa, Patrizia Tosi, Anna Marina Liberati, Antonello Pinto, Vincenzo Pavone, Filippo Gherlinzoni, Maria Paola Bianchi, Stefano Volpetti, Livio Trentin, Maria Cecilia Goldaniga, Maurizio Bonfichi, Amalia De Renzo, Corrado Schiavotto, Michele Spina, Angelo Michele Carella, Vittorio Stefoni, Lisa Argnani, Pier Luigi Zinzani
A large Italian multicenter observational retrospective study was conducted on the use of brentuximab vedotin (BV) for patients with relapsed Hodgkin's lymphoma (HL) to check if clinical trial results are confirmed even in a real life context. 234 CD30+ HL patients were enrolled. Best response was observed after a median of 4 cycles in 140 patients (59.8%): 74 (31.6%) patients obtained a complete response (CR) and 66 (28.2%) achieved a partial response (PR); overall response rate at the end of the treatment was 48...
October 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/29201819/asymmetric-atrophy-of-paraspinal-muscles-in-patients-with-chronic-unilateral-lumbar-radiculopathy
#3
Jinmann Chon, Hee-Sang Kim, Jong Ha Lee, Seung Don Yoo, Dong Hwan Yun, Dong Hwan Kim, Seung Ah Lee, Yoo Jin Han, Hyun Seok Lee, Young Rok Han, Seonyoung Han, Yong Kim
Objective: To assess the cross-sectional area (CSA) of the muscles for investigating the occurrence of asymmetry of the paraspinal (multifidus and erector spinae) and psoas muscles and its relation to the chronicity of unilateral lumbar radiculopathy using magnetic resonance imaging (MRI). Methods: This retrospective study was conducted between January 2012 to December 2014. Sixty one patients with unilateral L5 radiculopathy were enrolled: 30 patients had a symptom duration less than 3 months (group A) and 31 patients had a symptom duration of 3 months or more (group B)...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29194473/esmo-consensus-conference-on-malignant-lymphoma-general-perspectives-and-recommendations-for-the-clinical-management-of-the-elderly-patient-with-malignant-lymphoma
#4
C Buske, M Hutchings, M Ladetto, V Goede, U Mey, P Soubeyran, M Spina, R Stauder, M Trnený, U Wedding, P Fields
The European Society for Medical Oncology (ESMO) consensus conference on mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June 2015 in Lugano, Switzerland, and included a multidisciplinary panel of 25 leading experts. The aim of the conference was to develop recommendations on critical subjects difficult to consider in detail in the ESMO Clinical Practice Guidelines. The following areas were identified: (1) the elderly patient, (2) prognostic factors suitable for clinical use, and (3) the 'ultra-high-risk' group...
November 29, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29189284/the-use-of-liposomal-bupivacaine-in-erector-spinae-plane-block-to-minimize-opioid-consumption-for-breast-surgery-a-case-report
#5
Amanda Kumar, Alina Hulsey, Hector Martinez-Wilson, James Kim, Jeff Gadsden
The erector spinae plane block is a novel interfascial plane block that can provide thoracic and abdominal analgesia. We describe a patient with opioid intolerance scheduled for breast surgery who received an erector spinae plane block with liposomal bupivacaine as well as a supplemental T1 paravertebral block resulting in profound analgesia throughout her postoperative course. This case report demonstrates that use of liposomal bupivacaine in the erector spinae plane block can be successful in providing extended duration postoperative analgesia and minimizing systemic opioid requirements...
November 16, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29188074/heads-up-3d-vision-system-for-retinal-detachment-surgery
#6
Michele Coppola, Carlo La Spina, Alessandro Rabiolo, Giuseppe Querques, Francesco Bandello
Here we present procedural and safety results from our initial experience using 3D heads-up vitrectomy for retinal detachment surgery. The comparison with our outcomes from previous standard surgery shows how the new 3D system seems safe and effective.
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29187306/contribution-of-load-expectations-to-neuromechanical-adaptations-during-a-freestyle-lifting-task-a-pilot-study
#7
Anne Courbalay, Charles Tétreau, Arnaud Lardon, Thomas Deroche, Vincent Cantin, Martin Descarreaux
OBJECTIVES: The main goal of this study was to determine to what extent load expectations modulate neuromechanical adaptations in individuals with and without chronic low back pain (cLBP) when lifting and lowering various loads. The second goal was to assess the feasibility of a simple lifting protocol during which expectations about loads were manipulated. METHODS: Seventeen participants with cLBP and 18 participants without low back pain were asked to lift and lower boxes of mild to moderate loads...
October 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29187168/spasm-and-flexion-relaxation-phenomenon-response-to-large-lifting-load-during-the-performance-of-a-trunk-flexion-extension-exercise
#8
Yanjun Ma, Xinhai Shan
BACKGROUND: The flexion relaxation phenomenon (FRP) has been widely investigated. Nevertheless, no study has been reported on the FRP as well as spasm response to large lifting load. The aim of this study was to evaluate the effect of large lifting load on the FRP response and spasm during execution of a flexion-extension exercise. METHODS: Twenty-two healthy male university students without low back pain history participated this study. Subjects randomly performed three trials of trunk flexion-extension cycles of 5 s flexion and 5 s extension in each of 4 conditions (three large lifting loads of 15, 20 and 25 kg and one lifting load of 0 kg for comparison)...
November 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29186778/comparative-analysis-of-the-complete-chloroplast-genome-of-four-known-ziziphus-species
#9
(no author information available yet)
Ziziphus Mill. (Rhamnaceae) is comprised of about 170 species that are mainly distributed in tropical to subtropical regions, with few in the temperate zone. Several Ziziphus fruit tree species are important energy, nutrient, and medicinal resources for human populations, particularly for those living in rural regions. To date, limited genomic information is available for this genus. Here, we assembled the complete chloroplast genomes of four best known Ziziphus species, i.e., Ziziphus jujuba, Ziziphus acidojujuba, Ziziphus mauritiana, and Ziziphus spina-christi, based on the Illumina Paired-end sequencing method...
November 24, 2017: Genes
https://www.readbyqxmd.com/read/29184528/psychometric-properties-of-the-german-version-of-the-health-regulatory-focus-scale
#10
Bjarne Schmalbach, Roy Spina, Ileana Steffens-Guerra, Gabriele H Franke, Sören Kliem, Michalis P Michaelides, Andreas Hinz, Markus Zenger
The Health Regulatory Focus Scale (HRFS) is a short scale which measures an individual's prevention and promotion focus in a health-specific context. The main objective of this study was to examine the psychometric properties of the newly translated German version of the HRFS. Reliability and item characteristics were found to be satisfactory. Validity of both subscales toward other psychological constructs including behavioral approach and avoidance, core self-evaluations, optimism, pessimism, neuroticism, as well as several measures of physical and mental health was shown...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29176816/a-large-outbreak-of-hepatitis-e-virus-genotype-1-infection-in-an-urban-setting-in-chad-likely-linked-to-household-level-transmission-factors-2016-2017
#11
Alexander Spina, Annick Lenglet, David Beversluis, Marja de Jong, Larissa Vernier, Craig Spencer, Fred Andayi, Charity Kamau, Simone Vollmer, Boris Hogema, Andrea Irwin, Roger Ngueremi Yary, Açyl Mahamat Ali, Ali Moussa, Prince Alfani, Sibylle Sang
BACKGROUND: In September 2016, three acutely jaundiced (AJS) pregnant women were admitted to Am Timan Hospital, eastern Chad. We described the outbreak and conducted a case test-negative study to identify risk factors for this genotype of HEV in an acute outbreak setting. METHODS: Active case finding using a community based surveillance network identified suspected AJS cases. Pregnant or visibly ill AJS cases presenting at hospital were tested with Assure® IgM HEV rapid diagnostic tests (RDTs) and some with Polymerase Chain Reaction (PCR) in Amsterdam; confirmed cases were RDT-positive and controls were RDT-negative...
2017: PloS One
https://www.readbyqxmd.com/read/29175615/characterization-of-tissue-stiffness-of-the-infraspinatus-erector-spinae-and-gastrocnemius-muscle-using-ultrasound-shear-wave-elastography-and-superficial-mechanical-deformation
#12
Joseph P Kelly, Shane L Koppenhaver, Lori A Michener, Laurel Proulx, Francis Bisagni, Joshua A Cleland
The aim of this study was to compare measurement methods of tissue stiffness using ultrasound shear wave elastography (SWE) and superficial mechanical deformation (MyotonPRO) in the infraspinatus, erector spinae, and gastrocnemius muscles. Thirty healthy volunteers were assessed during rest, 40% and 80% maximum voluntary isometric contraction (MVIC). Correlation of the two methods in the three muscle regions was significant (r = 0.23-0.71, p < .05), and strongest in the gastrocnemius. MyotonPRO reliability was excellent (ICC > 0...
November 11, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29174233/effectiveness-of-gamma-knife-radiosurgery-in-improving-psychophysical-performance-and-patient-s-quality-of-life-in-idiopathic-trigeminal-neuralgia
#13
Filippo Gagliardi, Alfio Spina, Michele Bailo, Nicola Boari, Andrea Cavalli, Alberto Franzin, Arianna Fava, Antonella Del Vecchio, Angelo Bolognesi, Pietro Mortini
OBJECTIVE: To assess effectiveness of Gamma Knife Radiosurgery (GKRS) in improving quality of life (QoL) in patients with idiopathic trigeminal neuralgia (TN). METHODS: Between January 2001 and October 2013, 166 patients with medically resistant TN were treated at our Institution with GKRS. Patients were divided into two groups: TTN (typical trigeminal neuralgia) and ATN (atypical trigeminal neuralgia) patients. All patients underwent clinical evaluation using Marseille, BNI (Barrow Neurological Institute) pain and numbness scores, moreover they completed the Short Form (36) Health Survey (SF-36), ADL (Activity Daily Living) and EGFP (Excellent Good Fair Poor) questionnaires, and underwent psychological and neurological examination...
November 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29171789/accuracy-of-identification-of-low-or-high-risk-lifting-during-standardized-lifting-situations
#14
Mikkel Brandt, Pascal Madeleine, Afshin Samani, Markus Due Jakobsen, Sebastian Skals, Jonas Vinstrup, Lars Louis Andersen
The aim was to classify lifting activities into low and high risk categories (according to The Danish Working Environment Authority guidelines) based on surface electromyography (sEMG) and trunk inclination (tri-axial accelerometer) measurements. Lifting tasks with different weights, horizontal distance and technique were performed. The lifting tasks were characterized by a feature vector composed of either the 90(th), 95(th) or 99(th) percentile of sEMG activity level and trunk inclinations during the task...
November 24, 2017: Ergonomics
https://www.readbyqxmd.com/read/29171445/the-epidemiology-of-tuberculous-dactylitis-a-case-report-and-review-of-literature
#15
REVIEW
Hana Sahli, Leila Roueched, Mohamed Ali Sbai, Asma Bachali, Rawdha Tekaya
The literature on tuberculous dactylitis is poor, and most literature consists of isolated case reports. The aim of this case series is to study the particularities and the epidemiological aspects of tuberculous dactylitis in Tunisian patients. Google and Medline search was done using key words "tuberculous dactylitis" and "spina ventosa." Only Tunisian reports in adult patients were included. Eleven cases including this mentioned case were included in this review. There was a female predominance, high frequency of trauma before disease installation, rarity of predisposing factors, and less inflammation in blood tests when comparing with other cases in literature...
October 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/29169197/sex-dependent-effect-of-metformin-on-serum-prolactin-levels-in-hyperprolactinemic-patients-with-type-2-diabetes-a-pilot-study
#16
Robert Krysiak, Witold Szkróbka, Bogusław Okopień
Background Metformin was found to reduce circulating levels of pituitary hormones. Objective The purpose of this study was to assess whether sex determines the effect of metformin on lactotroph secretory function. Methods The study population included 25 women and 12 men with mildly elevated serum prolactin levels (25-75 ng/mL). Because of concomitant type 2 diabetes, all participants were treated with metformin (3 g daily). Plasma levels of glucose and lipids, HOMA1-IR, serum levels of prolactin, thyrotropin and free thyroid hormones, as well as Jostel's, SPINA-GT and SPINA-GD indices were assessed at baseline and at the end of metformin treatment...
November 23, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29169096/neuromuscular-compensatory-strategies-at-the-trunk-and-lower-limb-are-not-resolved-following-an-acl-reconstruction
#17
Grant Boggess, Kristin Morgan, Darren Johnson, Mary Lloyd Ireland, Jeffrey A Reinbolt, Brian Noehren
BACKGROUND: Following anterior cruciate ligament reconstruction (ACLR), patients present with greater trunk ipsilateral lean, which may affect knee kinetics and increase re-injury risk. However, there has been little research into neuromuscular factors controlling the trunk and their relation to the knee between healthy and ACLR subjects. This is critical to establish in order to develop more directed and effective interventions. HYPOTHESIS: As compared to healthy control subjects, ACLR subjects will demonstrate increased erector spinae and rectus abdominis co-contraction, greater rectus abdominis force and greater hamstring force that is correlated to increased forward trunk lean...
November 13, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29154265/analysis-of-correlation-between-degeneration-of-lower-lumbar-paraspinal-muscles-and-spinopelvic-alignment-in-patients-with-osteoporotic-vertebral-compression-fracture
#18
Qiguang Li, Jianmin Sun, Xingang Cui, Zhensong Jiang, Tao Li
BACKGROUND: A few studies have pointed that trunk extensors may affect the spinopelvic alignment; however, little is known about the exact association between degeneration of lower lumbar paraspinal muscles and spinopelvic parameters. OBJECTIVE: The study aimed to analyze the relationship between degeneration of lower lumbar paraspinal muscles and spinopelvic alignment in patients with osteoporotic vertebral compression fracture (OVCF). METHODS: Thirty-nine OVCF patients were involved in this study...
November 6, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29153781/genetic-epidemiology-of-autosomal-recessive-hypercholesterolemia-in-sicily-identification-by-next-generation-sequencing-of-a-new-kindred
#19
Rossella Spina, Davide Noto, Carlo M Barbagallo, Roberto Monastero, Valeria Ingrassia, Vincenza Valenti, Roberta Baschi, Antonina Pipitone, Antonina Giammanco, Maria P La Spada, Gabriella Misiano, Chiara Scrimali, Angelo B Cefalù, Maurizio R Averna
BACKGROUND: Autosomal recessive hypercholesterolemia (ARH) is a rare inherited lipid disorder. In Sardinia, differently from other world regions, the mutated allele frequency is high. It is caused by mutations in the low-density lipoprotein receptor adaptor protein 1 gene. Fourteen different mutations have been reported so far; in Sardinia, 2 alleles (ARH1 and ARH2) explain most of the cases. Four ARH patients, all carriers of the ARH1 mutation, have been identified in mainland Italy and 2 in Sicily...
October 27, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29153707/the-influence-of-muscle-activation-on-impact-dynamics-during-lateral-falls-on-the-hip
#20
Daniel R Martel, Iris C Levine, Steven P Pretty, Andrew C Laing
Muscle activation has been demonstrated to influence impact dynamics during scenarios including running, automotive impacts, and head impacts. This study investigated the effects of targeted muscle activation magnitude on impact dynamics during low energy falls on the hip with human volunteers. Fifteen university-aged participants (eight females, seven males) underwent 12 lateral pelvis release trials. Half of the trials were muscle-'relaxed'; in the remaining 'contracted' trials participants isometrically contracted their gluteus medius to 20-30% of maximal voluntary contraction before the drop was initiated onto a force plate...
November 10, 2017: Journal of Biomechanics
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