keyword
https://read.qxmd.com/read/38494163/resection-arthroplasty-is-a-valuable-strategy-for-humeroradial-synostosis-a-case-report
#1
JOURNAL ARTICLE
Mariana Almeida, Takehiko Takagi, Akiko Torii, Shinichiro Takayama
A 15-year-old girl with humeroradial synostosis since birth underwent a resection arthroplasty. A trapezoidal resection osteotomy of approximately 2 cm was performed at the anterior part of the bone flexure. This resulted at 18 months in an elbow arc of motion of 60°-110° and forearm pronation/supination of 40° and 60° without postoperative complications and improved disabilities of the arm, shoulder and hand and Hand 20 scores. Radiographic analysis revealed a humeroradial joint with a maintained pseudarthrosis and hinged motion at the humeroulnar joint...
March 15, 2024: Journal of Hand Surgery Asian-Pacific Volume
https://read.qxmd.com/read/38021615/congenital-pseudoarthrosis-of-tibia-with-anterolateral-bowing-treated-with-ilizarov-ring-fixator-a-case-report
#2
Amit Kale, Vishal S Patil, Parminder Singh, Harsh Raithatha, Meet Shah, Rishabh Aggarwal
Congenital pseudarthrosis of the tibia (CPT) is a rare, dysplastic condition that is characterized by a "false joint" in the tibia, leading to potential disability. We present a rare case report of a 12-year-old male from India with a history of neurofibromatosis type 1 (NF1) and anterolateral bowing of the tibia since birth. He sustained a tibial fracture during play. X-ray evaluation confirmed the fracture, and a clinical diagnosis of CPT was established. The treatment involved corticotomy for deformity correction and stabilization using Ilizarov's ring fixation...
October 2023: Curēus
https://read.qxmd.com/read/37994127/-analysis-of-clinical-features-and-variants-of-nf1-gene-in-12-patients-with-neurofibromatosis-type-1
#3
JOURNAL ARTICLE
Yuxin Zhang, Lulu Yan, Min Xie, Jiangyang Xue, Danyan Zhuang, Haibo Li
OBJECTIVE: To explore the types of NF1 gene variants and clinical characteristics among patients with Neurofibromatosis type I (NF1). METHODS: Clinical data of 12 patients diagnosed at Ningbo Women and Children's Hospital between December 2019 and May 2022 were retrospectively analyzed. The probands and their family members were subjected to high-throughput sequencing, and candidate variants were verified by Sanger sequencing and chromosome microarray analysis. RESULTS: The 12 patients had ranged from 4 months to 27 years old, with a male-to-female ratio of 2 : 1...
December 10, 2023: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://read.qxmd.com/read/37947855/-corrective-osteotomies-around-the-knee-joint-using-hexapods
#4
REVIEW
Jörg Dickschas
OBJECTIVE: Correction of deformities around the knee joint in the frontal and sagittal axis, torsion, length and translation. INDICATIONS: Complex deformities of the proximal tibia, and to a lesser extent of the distal femur, which cannot be treated with acute correction using plate or nail osteosynthesis. CONTRAINDICATIONS: Nicotine abuse, soft tissue problems, lack of patient compliance. SURGICAL TECHNIQUE: First, mounting of the proximal ring of the ring fixator strictly parallel to the joint line in 2 planes, fixation with 3 or 4 pins or wires...
November 10, 2023: Operative Orthopädie und Traumatologie
https://read.qxmd.com/read/37889407/postoperative-ct-imaging-to-characterize-fusion-in-pediatric-and-adolescent-vertebral-column-resection
#5
JOURNAL ARTICLE
K Aaron Shaw, Kendall Anigian, Daniel J Sucato
BACKGROUND: Vertebral column resection (VCR) is a powerful corrective technique for the management severe, rigid spinal deformities but does carry a relatively high complications rate. One of the feared complications is pseudarthrosis which places the patient at risk for implant failure. We present a single-center experience with post-operative computed tomography (CT) imaging at the osteotomy site to screen for impending pseudarthrosis. METHODS: A retrospective review of a single surgeon series of posterior-only VCR performed for severe pediatric and adolescent spinal deformities was performed...
October 27, 2023: Spine Deformity
https://read.qxmd.com/read/37858520/fast-track-surgery-for-children-with-congenital-pseudarthrosis-of-the-tibia-a-prospective-interventional-study
#6
JOURNAL ARTICLE
Yinzhi Yi, Lin Dong, Ni Zhang, Shasha Mo, Yonghong Xie, Xiongke Hu
OBJECTIVE: The purpose of this study was to explore the effect of fast-track surgery combined with a clinical nursing pathway on the recovery and complications of congenital pseudarthrosis of tibia. METHODS: 82 children with congenital pseudarthrosis of tibia admitted from January 2019 to December 2020 were selected as the study subjects. The control group received routine clinical nursing pathway while the intervention group received a fast-track surgery combined with a clinical nursing pathway...
September 27, 2023: International Journal of Orthopaedic and Trauma Nursing
https://read.qxmd.com/read/37810257/circ_0000888-regulates-osteogenic-differentiation-of-periosteal-mesenchymal-stem-cells-in-congenital-pseudarthrosis-of-the-tibia
#7
JOURNAL ARTICLE
Zhuoyang Li, Yaoxi Liu, Yiyong Huang, Qian Tan, Haibo Mei, Guanghui Zhu, Kun Liu, Ge Yang
Congenital pseudarthrosis of the tibia (CPT) is a refractory condition characterized by the decreased osteogenic ability in tibial pseudarthrosis repair. Periosteal mesenchymal stem cells (PMSCs) are multipotent cells involved in bone formation regulation. However, the mechanisms underlying its role in CPT remain unclear. In this study, we observed downregulation of circ_0000888 and pleiotrophin (PTN), as well as upregulation of miR-338-3p in CPT derived PMSCs (CPT-dPMSCs). Our results demonstrated that circ_0000888 and PTN likely enhanced the viability, proliferation, and osteogenic ability of PMSCs, while miR-338-3p had the opposite effect...
October 20, 2023: IScience
https://read.qxmd.com/read/37767661/-comparison-of-two-different-intramedullary-rods-combined-with-ilizarov-external-fixation-and-wrapped-autologous-iliac-bone-grafting-for-the-treatment-of-congenital-tibial-pseudarthrosis-in-children
#8
JOURNAL ARTICLE
X P Liu, K Liu
Objective: To compare the initial clinical efficacy of extensible intramedullary rod fixation and Williams intramedullary rod fixation combined with Ilizarov external fixation and wrapped autologous iliac bone grafting in the treatment of congenital tibial pseudarthrosis in children. Methods: A retrospective analysis was conducted on the clinical data of 60 children with Crawford Ⅳtype congenital pseudarthrosis of the tibia treated with combined surgery at the Orthopedics Department of Hunan Children's Hospital from January 2013 to December 2020...
September 27, 2023: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://read.qxmd.com/read/37568383/vascularized-growth-plate-transfer-in-paediatric-ulna-non-union-operative-technique-and-review-of-the-literature
#9
Nisha M Grünberger, Amelie Klein, Marina Barandun, Dirk J Schaefer, Andreas H Krieg, Alexandre Kaempfen
Congenital pseudarthrosis of forearm fractures is rare and is strongly associated with neurofibromatosis type 1 (NF1). Our case report illustrates the progression of a non-union of the ulna after minor trauma in a twelve-year-old boy, newly diagnosed with NF1, and presents the technique of microsurgical bone reconstruction, including the growth plate. More than seven years after the first operation, follow-up presents a favorable outcome with a pain-free patient and unrestricted function of the forearm after a secondary correction of the remaining radial bowing...
July 28, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37508581/questions-about-using-the-induced-membrane-technique-to-manage-cases-of-congenital-tibial-pseudarthrosis
#10
EDITORIAL
Céline Klein, Florelle Gindraux, Alain-Charles Masquelet, Romuald Mentaverri, Richard Gouron
The induced membrane technique is an innovative approach for repairing critical bone defects and has been applied recently in patients with congenital pseudarthrosis of the tibia (CPT). CPT is frequently associated with neurofibromatosis type 1 (NF1). Here, we briefly describe the clinical results of the induced membrane technique in NF1-deficient patients with CPT and in an animal model of CPT. Furthermore, we discuss the hypotheses used to explain inconsistent outcomes for the induced membrane technique in CPT-especially when associated with NF1...
July 24, 2023: Cells
https://read.qxmd.com/read/37400210/-long-term-follow-up-evaluation-of-combined-surgery-for-congenital-tibial-pseudarthrosis-in-children
#11
JOURNAL ARTICLE
Y X Liu, G Yang, X K Hu, Q Tan, H Pan, K Liu, Y Y Huang, A Yan, G H Zhu, H B Mei
Objective: To explore the long-term effect of combined surgery for the treatment of congenital tibial pseudarthrosis in children. Methods: The clinical data of 44 children with congenital tibial pseudarthrosis who underwent combined surgery (tibial pseudarthrosis tissue resection, intramedullary rod fixation, wrapped autologous iliac bone graft, Ilizarov external fixator fixation) from August 2007 to October 2011 at the Department of Pediatric Orthopedics, Hunan Children's Hospital were collected. There were 33 males and 11 females...
June 30, 2023: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://read.qxmd.com/read/37311312/treatment-of-concomitant-congenital-pseudarthrosis-of-the-fibula-with-propeller-periosteal-flap
#12
JOURNAL ARTICLE
Tarek Abdalla El-Gammal, Amr El-Sayed Ali, Mohamed Mostafa Kotb, Waleed Riad Saleh, Yasser Farouk Ragheb, Omar Ahmed Refai, Mohamed Mohamed Morsy, Yousif Tarek El-Gammal
INTRODUCTION: Congenital pseudarthrosis of the fibula is not an uncommon condition to accompany congenital pseudarthrosis of the tibia. Persistence of the fibular pseudarthrosis has been linked to inferior outcomes including tibial union and alignment, refractures, and ankle alignment. In this report, we present the results of a pedicled periosteal propeller flap technique for the treatment of fibular pseudarthrosis. METHODS: Ten children with an average age at surgery of 5...
June 1, 2023: Annals of Plastic Surgery
https://read.qxmd.com/read/37307403/refracture-a-potential-complication-of-the-periosteal-flap-technique-without-bone-graft-for-isolated-congenital-pseudarthrosis-of-the-fibula-a-report-of-two-cases-and-literature-review
#13
REVIEW
Ramin Zargarbashi, Mazaher Ebrahimian, Salar Baghbabi, Alireza Moharrami, Younes Basti
BACKGROUND: It is a rare condition defined by congenital pseudarthrosis of the fibula (CPF), which may be associated with neurofibromatosis (NF) and congenital pseudarthrosis of the tibia. A condition such as this may be symptomatic or asymptomatic, but it requires treatment because of the progression of signs such as ankle valgus and pseudarthrosis of the tibia. There are a number of surgical techniques that can be used to treat this condition, such as tibiofibular fusion, internal fixation, the Ilizarov method, and periosteal flap...
June 1, 2023: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/37279298/thoracic-outlet-syndrome-secondary-to-vascular-insufficiency-from-congenital-pseudarthrosis-of-the-clavicle-a-case-report
#14
JOURNAL ARTICLE
Alexander A Hysong, Sahitya K Denduluri, Frank R Arko, Peter M Waters, Bryan J Loeffler
CASE: An 18-year-old woman with a history of congenital pseudarthrosis of the clavicle (CPC) presented with episodes of right upper extremity ischemia. Vascular studies demonstrated an extensive thrombus with complete occlusion of the brachial artery. She underwent urgent thrombectomy. Subsequently, she underwent first rib resection and scalenectomy as well as pseudarthrosis takedown and fixation. Postoperatively, she returned to Division I collegiate soccer with complete symptomatic resolution...
April 1, 2023: JBJS Case Connector
https://read.qxmd.com/read/37181425/anterolateral-congenital-tibial-bowing-case-report
#15
Giuseppe Mastantuoni, Angelo Gabriele Aulisa, Marco Giordano, Pietro Savignoni, Renato Maria Toniolo, Francesco Falciglia
BACKGROUND: The treatment of congenital curvatures (bowing) of the tibia still represents a challenging problem for all pediatric orthopedic surgeons because of its unpredictable course, especially if pseudoarthrosis occurs after a pathologic fracture of the tibia. CASE PRESENTATION: We describe the case of a child affected by an isolated curvature of his left leg. The congenital malformation was discovered at birth and no other pathological clinical finding was present...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/36941117/congenital-pseudarthrosis-of-the-tibia-long-term-outcome-of-treatment-with-intramedullary-vascularized-fibular-graft-combined-with-ilizarov-dstraction
#16
JOURNAL ARTICLE
Tarek Abdalla El-Gammal, Amr El-Sayed Ali, Mohamed Mostafa Kotb, Waleed Riad Saleh, Yasser Farouk Ragheb, Omar Ahmed Refai, Mohamed Mohamed Morsy, Yousif Tarek El-Gammal
BACKGROUND: Late presenting cases of congenital pseudarthrosis of the tibia, are further complicated with severe shortening. Limb length discrepancy (LLD) cannot be corrected by vascularized fibular grafting and the use of Ilizarov distraction is associated with a high rate of complications. The aim of this study was to report the long-term follow-up of a combined technique previously published under the name "telescoping vascularized fibular graft". MATERIALS AND METHODS: Eleven patients operated at an average age of 10...
March 20, 2023: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/36912081/is-it-a-good-choice-for-physeal-distraction-osteogenesis-to-treat-cpt-patients-with-tibial-shortening
#17
JOURNAL ARTICLE
Yaoxi Liu, Qian Tan, Kun Liu, Ge Yang, Guanghui Zhu, Jiangyan Wu, Haibo Mei
OBJECTIVE: The purpose of this study was to evaluate the healing index and complications of distraction osteogenesis through the physis in children with Congenital pseudarthrosis of the tibia (CPT) using Ilizarov external fixation device. METHODS: Nine children with CPT who underwent distraction osteogenesis through the physis surgery with an Ilizarov external fixation device between June 2018 and August 2020 were included in the study. The average follow-up time was 36...
March 13, 2023: Journal of Pediatric Orthopedics. Part B
https://read.qxmd.com/read/36863762/association-between-preoperative-concurrent-fibular-pseudarthrosis-and-risk-of-postoperative-ankle-valgus-in-patients-with-congenital-pseudarthrosis-of-the-tibia
#18
JOURNAL ARTICLE
Hui Yu, Zhuoyang Li, Qian Tan, Kun Liu, Guanghui Zhu, Haibo Mei, Ge Yang
BACKGROUND: This study evaluated the correlation of preoperative concurrent fibular pseudarthrosis with the risk of ankle valgus deformity in patients with congenital pseudarthrosis of the tibia (CPT) who underwent successful surgical treatment. METHOD: The children with CPT who were treated at our institution between 1 January 2013 and 31 December 2020 were retrospectively reviewed. The independent variable was preoperative concurrent fibular pseudarthrosis, and the dependent variable was postoperative ankle valgus...
February 2023: BMJ Paediatrics Open
https://read.qxmd.com/read/36814904/differential-expression-and-effect-analysis-of-lncrna-mrna-in-congenital-pseudarthrosis-of-the-tibia
#19
JOURNAL ARTICLE
Zhuoyang Li, Haibo Mei, Kun Liu, Ge Yang
Background: To analyze the lncRNA-mRNA differential expression and co-expression network of periosteal stem cells (PSCs) from congenital pseudarthrosis of the tibia (CPT) and normal patients, and to explore the role of key lncRNAs. Methods: Differentially expressed lncRNAs and mRNAs in PSCs were obtained by sequencing, and biological functions of differentially expressed mRNAs were detected by gene ontology (GO), Kyoto encyclopedia of genes and genomes (KEGG) pathway and protein -protein interaction (PPI) analysis...
2023: Frontiers in Genetics
https://read.qxmd.com/read/36814736/traumatic-radius-pseudoarthrosis-in-neurofibromatosis-type-1-all-treatment-options-in-one-patient
#20
Çağdaş Pamuk, Ülker Moralar
Although congenital pseudoarthrosis of the radius is a rare case, it has been reported many times in the literature in the past and it has been shown that it can be associated with neurofibromatosis type 1. However, traumatic radius pseudoarthrosis has never been reported before. In this case report, all treatment options were applied to the same patient over a four-year period and the results were reported. A two-year-old boy had a left radius diaphysis fracture after a simple fall, and bone union could not be achieved despite the application of cast immobilization, internal fixation grafting, and electrical stimulation in an external center...
January 2023: Curēus
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