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Scrambler therapy

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https://www.readbyqxmd.com/read/27756587/effects-of-pain-scrambler-therapy-for-management-of-burn-scar-pruritus-a-pilot-study
#1
So Young Joo, Yoon Soo Cho, Sung-Rae Cho, Dohern Kym, Cheong Hoon Seo
PURPOSE: Pain Scrambler therapy is a patient-specific electrocutaneous nerve stimulation device. Burn pruritus is a common form of chronic and disabling neuropathic pain that is often difficult to treat effectively. Pruritus is mediated by histamines, which are effector molecules stored in mast cells and released locally during injury or inflammation. Burn pruritus may be accompanied by peripheral neuropathic pain, which may result from injury to sensory nerves that hampers conductance of neuronal messages along the large A and small C afferent fibers to the spinal cord...
October 15, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27512291/effect-of-pain-scrambler-therapy-on-shoulder-joint-pain-and-range-of-motion-in-patients-who-had-undergone-arthroscopic-rotator-cuff-repair-for-the-first-time
#2
Dong-Kyu Lee, Eun-Kyung Kim
[Purpose] This study aimed to determine the effect of pain scrambler therapy on shoulder joint pain and range of motion in patients who had undergone arthroscopic rotator cuff repair for the first time. [Subjects and Methods] Pain scrambler therapy was administered once a day every 40 minutes for 10 days to patients that had undergone arthroscopic rotator cuff repair for the first time. The visual analog scale was used to measure pain, and a goniometer was used to measure shoulder range of motion. [Results] After 10 sessions of pain scrambler therapy, pain was significantly reduced from that before the treatment...
July 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27370908/scrambler-therapy-%C3%A2-mc-5a-for-complex-regional-pain-syndrome-case-reports
#3
Umberto Raucci, Caterina Tomasello, Marcello Marri, Marco Salzano, Augusto Gasparini, Elena Conicella
BACKGROUND: Complex regional pain syndrome (CRPS) is a disorder that is often challenging to treat and can be associated with a prolonged course of severe pain. Therapy of CRPS remains controversial; the pain often can be very difficult to control, and treatment includes medications, physical therapy, regional anesthesia, and neuromodulation. AIM: We evaluated Scrambler Therapy(®) (ST) in terms of efficacy, safety, and durability of treatment effect in patients suffering from CRPS...
September 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27330020/treatment-of-human-immunodeficiency-virus-related-peripheral-neuropathy-with-scrambler-therapy-a-case-report
#4
Thomas J Smith, Paul Auwaerter, Amy Knowlton, Deanna Saylor, Justin McArthur
Peripheral neuropathy is one of the most common neurological complications of HIV infection with a 30-60% lifetime prevalence. Newer HIV drugs cause less peripheral neuropathy, but patients are now living long enough to develop concomitant diabetes-related, vascular-related, and chemotherapy-related neuropathy so it continues as a major debilitating issue. Recent national CDC guidelines have stressed the importance of non-opioid therapies, especially in this population that may have had drug abuse problems...
June 21, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27041741/scrambler-therapy-for-the-management-of-chronic-pain
#5
REVIEW
Neil Majithia, Thomas J Smith, Patrick J Coyne, Salahadin Abdi, Deirdre R Pachman, Daniel Lachance, Randy Shelerud, Andrea Cheville, Jeffrey R Basford, David Farley, Carrie O'Neill, Kathryn J Ruddy, Frank Sparadeo, Andreas Beutler, Charles L Loprinzi
PURPOSE: Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and behavioral strategies exist for the management of this condition, treatment is often unsatisfactory. Scrambler Therapy is a novel, non-invasive pain modifying technique that utilizes trans-cutaneous electrical stimulation of pain fibers with the intent of re-organizing maladaptive signaling pathways. This review was conducted to further evaluate what is known regarding the mechanisms and mechanics of Scrambler Therapy and to investigate the preliminary data pertaining to the efficacy of this treatment modality...
June 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/26977329/use-of-scrambler-therapy-in-acute-paediatric-pain-a-case-report-and-review-of-the-literature
#6
Sabrina Congedi, Silvia Spadini, Chiara Di Pede, Martina Ometto, Tatiana Franceschi, Valentina De Tommasi, Caterina Agosto, Pierina Lazzarin, Franca Benini
We report our clinical experience on the effect of Scrambler Therapy (ST) for a child with acute mixed pain refractory to pharmacological treatment. ST, recently proposed as an alternative treatment for chronic neuropathic pain in adults, is a noninvasive approach to relieve pain, by changing pain perception at brain level. It is safe and has no side effects. Further research is needed to assess its efficacy for acute pain and for paediatric population.
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/26422429/chronic-pain-treatment-and-scrambler-therapy-a-multicenter-retrospective-analysis
#7
Christian Compagnone, Fernanda Tagliaferri
BACKGROUND AND AIM: Scrambler Therapy is a novel neuromodulation that works by electrocutaneous stimulation in a non-invasive manner through C fibers surface receptors. It substitutes pain information with synthetic "non pain" information. The primary aim of this study was to analyze the efficacy and safety of Scrambler Therapy after ten sessions related to different usage conditions and different learning curves that occur in a multi-center study. METHODS: 201 patients have been treated with Scrambler Therapy...
2015: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/26408323/pilot-evaluation-of-scrambler-therapy-for-pain-induced-by-bone-and-visceral-metastases-and-refractory-to-standard-therapies
#8
Paolo Notaro, Carlo Alberto Dell'Agnola, Alessandro J Dell'Agnola, Alessio Amatu, Katia Bruna Bencardino, Salvatore Siena
PURPOSE: Scrambler therapy is a non-invasive neurocutaneous electrical pain intervention, effective for the treatment of neuropathic pain. Currently, few data about the efficacy of this treatment in cancer pain induced by skeletal and visceral metastases are available. The aim of this single-center case series is to evaluate the efficacy of scrambler therapy in reducing this kind of cancer pain after failure of standard treatments, including pharmacological therapies and radiation therapy...
April 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/25245776/pilot-evaluation-of-scrambler-therapy-for-the-treatment-of-chemotherapy-induced-peripheral-neuropathy
#9
RANDOMIZED CONTROLLED TRIAL
Deirdre R Pachman, Breanna L Weisbrod, Drew K Seisler, Debra L Barton, Kelliann C Fee-Schroeder, Thomas J Smith, Daniel H Lachance, Heshan Liu, Randy A Shelerud, Andrea L Cheville, Charles L Loprinzi
PURPOSE: Chemotherapy-induced peripheral neuropathy (CIPN), a common side effect of chemotherapy, needs better effective treatments. Preliminary data support the use of Scrambler therapy, a device which treats pain via noninvasive cutaneous electrostimulation, for the treatment of CIPN. The current manuscript reports data from a pilot trial, performed to investigate the effect of Scrambler therapy for the treatment of established CIPN. METHODS: Eligible patients had CIPN symptoms of ≥1 month duration with tingling and/or pain ≥4/10 during the prior week...
April 2015: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/25232861/predictive-factors-associated-with-success-and-failure-for-calmare-scrambler-therapy-a-multicenter-analysis
#10
MULTICENTER STUDY
Jee Youn Moon, Connie Kurihara, Judith P Beckles, Karen E Williams, David E Jamison, Steven P Cohen
OBJECTIVE: Calmare (Scrambler) therapy is a novel therapeutic modality that purports to provide pain relief by "scrambling" afferent pain signals and replacing them with "non-pain" information through conventional lines of neural transmission. The goal of this study is to identify which factors are associated with treatment outcome for Calmare therapy. METHODS: Data were garnered from 3 medical centers on 147 patients with various pain conditions who underwent a minimum of either 3 Calmare therapies on consecutive days or 5 therapies overall...
August 2015: Clinical Journal of Pain
https://www.readbyqxmd.com/read/25119581/therapeutic-strategies-for-cancer-treatment-related-peripheral-neuropathies
#11
REVIEW
Deirdre R Pachman, James C Watson, Charles L Loprinzi
Chemotherapy-induced peripheral neuropathy (CIPN) is a common toxicity associated with multiple chemotherapeutic agents. CIPN may have a detrimental impact on patients' quality of life and functional ability, as well as result in chemotherapy dose reductions. Although symptoms of CIPN can improve with treatment completion, symptoms may persist. Currently, the treatment options for CIPN are quite limited. Duloxetine, a serotonin-norepinephrine reuptake inhibitor, has the most evidence supporting its use in the treatment of CIPN...
December 2014: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/24143893/a-trial-of-scrambler-therapy-in-the-treatment-of-cancer-pain-syndromes-and-chronic-chemotherapy-induced-peripheral-neuropathy
#12
Patrick J Coyne, Wen Wan, Patricia Dodson, Craig Swainey, Thomas J Smith
Neuropathic pain is common among cancer patients and often difficult to treat. This study used Scrambler therapy, a patient-specific electrocutaneous nerve stimulation device, to treat cancer patients with pain. Patients received Scrambler therapy for 10 sessions (one daily) over a two-week period. The primary outcome was changed in pain numerical rating scale (NRS) at one month; secondary outcomes were changes in the Brief Pain Inventory and European Organization for Treatment and Cancer QLC-CIPN-20(EORTC CIPN-20), over time...
December 2013: Journal of Pain & Palliative Care Pharmacotherapy
https://www.readbyqxmd.com/read/23838448/treatment-of-postherpetic-pain-with-scrambler-therapy-a-patient-specific-neurocutaneous-electrical-stimulation-device
#13
Thomas J Smith, Giuseppe Marineo
: Objectives:Postherpetic neuropathy (PHN) is common, severe, and often refractory to treatment. We treated 10 patients with refractory PHN using Scrambler therapy, a neurocutaneous stimulation device that delivers "nonpain" information with surface electrodes. METHODS: Scrambler therapy was given as 30-minute sessions daily for 10 days. Pain was recorded before and after treatment. Two centers.Result:The average pain score rapidly diminished from 7.64 ± 1.46 at baseline to 0...
July 8, 2013: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/23342218/clinical-experiences-on-the-effect-of-scrambler-therapy-for-patients-with-postherpetic-neuralgia
#14
Young Kwon Ko, Ho Young Lee, Wang Yong Lee
Postherpetic neuralgia (PHN) is a debilitating complication of herpes zoster, especially in elderly and comorbid patients. Unfortunately, the currently available treatments have shown limited efficacy and some adverse events that are poorly tolerated in elderly patients. Scrambler Therapy, proposed as an alternative treatment for chronic neuropathic pain recently, is a noninvasive approach to relieve pain by changing pain perception at the brain level. Here, we report our clinical experiences on the effect of Scrambler Therapy for three patients with PHN refractory to conventional treatment...
January 2013: Korean Journal of Pain
https://www.readbyqxmd.com/read/23342211/scrambler-therapy-for-patients-with-cancer-pain-case-series
#15
Hong Sik Park, Woo Kyung Sin, Hye Young Kim, Jee Youn Moon, Soo Young Park, Yong Chul Kim, Sang Chul Lee
More than 80% of cancer patients experience cancer pain. Among them, more than 50% experience moderate to severe pain. To control cancer pain, a variety of methods have been used, including medications and nerve blocks. In some patients, however, it is impossible to perform nerve blocks due to caner metastasis into the epidural space, while in other patients, opioid dose escalation is impossible due to opioid side effects; thus, cancer pain management is difficult. Scrambler therapy is a novel approach for pain control that uses EKG-like pads, which are applied above and below the site of pain...
January 2013: Korean Journal of Pain
https://www.readbyqxmd.com/read/23016475/prospective-study-of-application-of-biological-communication-cybernatics-in-management-of-chronic-low-back-pain-a-preliminary-report
#16
R K Ghatak, S N Nandi, A Bhakta, G C Mandal, M Bandyopadhyay, S Kumar
To observe the effects of application of cybernetics (theories of communication). This is an open level prospective study, involving patients with chronic low back pain of more than 3 months. Assessment were done before the start of therapy and after the completion of therapy every day for consecutive 6 days of treatment protocol. A total of 8 patients were enrolled (4 male, 4 female). The Visual Analogue Scale (VAS) was used to assess pain, Oswestry Disability Scale (ODI) was applied for scoring disability...
December 2011: Nepal Medical College Journal: NMCJ
https://www.readbyqxmd.com/read/21763099/scrambler-therapy-may-relieve-chronic-neuropathic-pain-more-effectively-than-guideline-based-drug-management-results-of-a-pilot-randomized-controlled-trial
#17
RANDOMIZED CONTROLLED TRIAL
Giuseppe Marineo, Vittorio Iorno, Cristiano Gandini, Vincenzo Moschini, Thomas J Smith
CONTEXT: Neuropathic pain is common, disabling, and often difficult to treat. OBJECTIVES: To compare guideline-based drug management with Scrambler therapy, a patient-specific electrocutaneous nerve stimulation device. METHODS: A clinical trial with patients randomized to either guideline-based pharmacological treatment or Scrambler therapy for a cycle of 10 daily sessions was performed. Patients were matched by type of pain including postsurgical neuropathic pain, postherpetic neuralgia, or spinal canal stenosis...
January 2012: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/16012423/scrambler-therapy
#18
A F Sabato, G Marineo, A Gatti
UNLABELLED: In neuropathies there are complex reactions that modify the homeostatic equilibrium of pain system. In such a context the Scrambler Therapy (ST5) interferes with pain signal transmission, by ''mixing'' a ''non-pain'' information into the nerve fibres. The aim of this study is to evaluate the effectiveness of ST5 in the treatment of neuropathic pain. The ST5 consists of a multiprocessor apparatus able to simulate 5 artificial neurons by the application of surface electrodes on skin pain areas...
July 2005: Minerva Anestesiologica
https://www.readbyqxmd.com/read/12555009/untreatable-pain-resulting-from-abdominal-cancer-new-hope-from-biophysics
#19
Giuseppe Marineo
CONTEXT: Visceral pain characterizing pancreatic cancer is the most difficult symptom of the disease to control and can significantly impair the quality of life which remains and increase the demand for euthanasia. AIM: To investigate a possible new method based on biophysical principles (scrambler therapy) to be used in the effective treatment of drug-resistant oncological pain of the visceral/neuropathic type. SETTING: Eleven terminal cancer patients (3 pancreas, 4 colon, 4 gastric) suffering from elevated drug resistant visceral pain...
January 2003: JOP: Journal of the Pancreas
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