Neil Majithia, Thomas J Smith, Patrick J Coyne, Salahadin Abdi, Deirdre R Pachman, Daniel Lachance, Randy Shelerud, Andrea Cheville, Jeffrey R Basford, David Farley, Carrie O'Neill, Kathryn J Ruddy, Frank Sparadeo, Andreas Beutler, Charles L Loprinzi
PURPOSE: Chronic pain is a widespread and debilitating condition, encountered by physicians in a variety of practice settings. Although many pharmacologic and behavioral strategies exist for the management of this condition, treatment is often unsatisfactory. Scrambler Therapy is a novel, non-invasive pain modifying technique that utilizes trans-cutaneous electrical stimulation of pain fibers with the intent of re-organizing maladaptive signaling pathways. This review was conducted to further evaluate what is known regarding the mechanisms and mechanics of Scrambler Therapy and to investigate the preliminary data pertaining to the efficacy of this treatment modality...
June 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer