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https://www.readbyqxmd.com/read/29217675/ten-year-mortality-in-the-wise-study-women-s-ischemia-syndrome-evaluation
#1
Tanya S Kenkre, Pankaj Malhotra, B Delia Johnson, Eileen M Handberg, Diane V Thompson, Oscar C Marroquin, William J Rogers, Carl J Pepine, C Noel Bairey Merz, Sheryl F Kelsey
BACKGROUND: The WISE study (Women's Ischemia Syndrome Evaluation) was a prospective cohort study of 936 clinically stable symptomatic women who underwent coronary angiography to evaluate symptoms and signs of ischemia. Long-term mortality data for such women are limited. METHODS AND RESULTS: Obstructive coronary artery disease (CAD) was defined as ≥50% stenosis on angiography by core laboratory. We conducted a National Death Index search to assess the mortality of women who were alive at their final WISE contact date...
December 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29202104/a-health-profile-of-senior-aged-women-veterans-a-latent-class-analysis-of-condition-clusters
#2
Margaret E Gonsoulin, Ramon A Durazo-Arvizu, Karen M Goldstein, Guichan Cao, Qiuying Zhang, Dharani Ramanathan, Denise M Hynes
Background and Objectives: This study characterizes the multiple morbidities experienced by senior-aged women Veterans so that the Veterans Health Administration (VHA) and other healthcare systems may be better prepared to meet the healthcare needs of this growing cohort. Research Design and Methods: Using the VHA's Corporate Data Warehouse (CDW), we conducted a retrospective observational study of the 38,597 female veteran patients who were at least sixty-five years old and received care in the VHA during 2013 and 2014...
September 1, 2017: Innovation in Aging
https://www.readbyqxmd.com/read/29132221/2009-iom-guidelines-for-gestational-weight-gain-how-well-do-they-predict-outcomes-across-ethnic-groups
#3
Amal R Khanolkar, Gillian E Hanley, Ilona Koupil, Patricia A Janssen
OBJECTIVE: To determine whether the Institute Of Medicine's (IOM) 2009 guidelines for weight-gain during pregnancy are predictive of maternal and infant outcomes in ethnic minority populations. METHODS: We designed a population-based study using administrative data on 181,948 women who delivered live singleton births in Washington State between 2006-2008. We examined risks of gestational hypertension, preeclampsia/eclampsia, cesarean delivery, and extended hospital stay in White, Black, Native-American, East-Asian, Hispanic, South-Asian and Hawaiian/Pacific islander women according to whether they gained more or less weight during pregnancy than recommended by IOM guidelines...
November 13, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29081008/hypertension-in-african-americans
#4
REVIEW
Nomsa Musemwa, Crystal A Gadegbeku
PURPOSE OF REVIEW: African Americans are over-burdened with hypertension resulting in excess morbidity and mortality. We highlight the health impact of hypertension in this population, review important observations regarding disease pathogenesis, and outline evidence-based treatment, current treatment guidelines, and management approaches. RECENT FINDINGS: Hypertension accounts for 50% of the racial differences in mortality between Blacks and Whites in the USA. Genome-wide association studies have not clearly identified distinct genetic causes for the excess burden in this population as yet...
October 28, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28911306/management-of-blood-pressure-and-heart-rate-in-patients-with-diabetes-mellitus
#5
Ioanna Gouni-Berthold, Ruth Hanssen, Lisa Ravarani, Heiner K Berthold
BACKGROUND: In patients with diabetes mellitus (DM) there is a clear association between blood pressure (BP) levels and macrovascular and microvascular complications. However, the BP targets that need to be achieved for optimal outcomes remain controversial. METHODS: The purpose of this narrative review is to discuss BP targets and management in patients with DM. The subject of elevated heart rate, which has been associated with mortality in many populations, and which is observed in some patients with DM will also be addressed...
June 8, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28828478/association-of-jnc-8-and-sprint-systolic-blood-pressure-levels-with-cognitive-function-and-related-racial-disparity
#6
Ihab Hajjar, Kristine J Rosenberger, Ambar Kulshreshtha, Hilsa N Ayonayon, Kristine Yaffe, Felicia C Goldstein
Importance: The Eighth Joint National Committee (JNC-8) recommended treating systolic blood pressure (SBP) to a target below 150 mm Hg in older adults, whereas data from the Systolic Blood Pressure Intervention Trial (SPRINT) suggested that a SBP level of lower than 120 mm Hg decreases cardiovascular event rates. Target SBP guidelines have not addressed the potential that black patients may have greater morbidity and mortality from hypertension, especially with regard to cognitive outcomes...
October 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28770596/high-rates-of-viral-suppression-in-adults-and-children-with-high-cd4-counts-using-a-streamlined-art-delivery-model-in-the-search-trial-in-rural-uganda-and-kenya
#7
Dalsone Kwarisiima, Moses R Kamya, Asiphas Owaraganise, Florence Mwangwa, Dathan M Byonanebye, James Ayieko, Albert Plenty, Doug Black, Tamara D Clark, Bridget Nzarubara, Katherine Snyman, Lillian Brown, Elizabeth Bukusi, Craig R Cohen, Elvin H Geng, Edwin D Charlebois, Theodore D Ruel, Maya L Petersen, Diane Havlir, Vivek Jain
INTRODUCTION: The 2015 WHO recommendation of antiretroviral therapy (ART) for all HIV-positive persons calls for treatment initiation in millions of persons newly eligible with high CD4+ counts. Efficient and effective care models are urgently needed for this population. We evaluated clinical outcomes of asymptomatic HIV-positive adults and children starting ART with high CD4+ counts using a novel streamlined care model in rural Uganda and Kenya. METHODS: In the 16 intervention communities of the HIV test-and-treat Sustainable East Africa Research for Community Health Study (NCT01864603), all HIV-positive individuals irrespective of CD4 were offered ART (efavirenz [EFV]/tenofovir disoproxil fumarate + emtricitabine (FTC) or lamivudine (3TC)...
July 21, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28480530/opportunities-for-improving-cardiovascular-health-outcomes-in-adults-younger-than-65%C3%A2-years-with-guideline-recommended-statin-therapy
#8
Sara M Sarasua, Jiexiang Li, German T Hernandez, Keith C Ferdinand, Jonathan N Tobin, Kevin A Fiscella, Daniel W Jones, Angelo Sinopoli, Brent M Egan
The impact of age, race/ethnicity, healthcare insurance, and selected clinical variables on statin-preventable ASCVD were quantified in adults aged 21 to 79 years from National Health and Nutrition Examination Surveys 2007-2012 using the 2013 American College of Cardiology/American Heart Association guideline on the treatment of cholesterol. Among ≈42.4 million statin-eligible, untreated adults, 52.6% were hypertensive and 71% were younger than 65 years. Of ≈232 000 statin-preventable ASCVD events annually, most occur in individuals younger than 65 years, with higher proportions in blacks and Hispanics than whites (73...
May 7, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28346156/association-of-sleep-characteristics-with-cardiovascular-and-metabolic-risk-factors-in-a-population-sample-the-chicago-area-sleep-study
#9
Samantha E Montag, Kristen L Knutson, Phyllis C Zee, Jeffrey J Goldberger, Jason Ng, Kwang-Youn A Kim, Mercedes R Carnethon
OBJECTIVES: To investigate the association of sleep characteristics with prevalent hypertension, diabetes, and obesity in a multiethnic cohort. DESIGN: This study used a population-based cross-sectional study design. SETTING: Participants were recruited between 2009 and 2011 from Chicago, Illinois, and the surrounding suburbs. PARTICIPANTS: Participants were 492 adults aged 35 to 64years who self-reported as white, black, Hispanic, or Asian and who had a low likelihood of sleep apnea based on the apnea screening questionnaires and 1 night of apnea screening using an in-home device (apnea hypopnea index <15 or oxygen desaturation index <10)...
April 2017: Sleep Health
https://www.readbyqxmd.com/read/28237284/comparison-of-delay-times-from-symptom-onset-to-medical-contact-in-blacks-versus-whites-with-acute-myocardial-infarction
#10
COMPARATIVE STUDY
Amy Leigh Miller, DaJuanicia Simon, Matthew T Roe, Michael C Kontos, Deborah Diercks, Ezra Amsterdam, Deepak L Bhatt
Clinical outcomes in acute myocardial infarction (AMI) worsen with increasing delay between symptom onset and clinical presentation. Previous studies have shown that black patients with AMI have longer presentation delays. The objective of this analysis is to explore the potential contribution of community factors to presentation delays in black patients with AMI. We linked clinical data for 346,499 consecutive patients with AMI from Acute Coronary Treatment Intervention Outcomes Network Registry-Get With the Guidelines™ (2007-2014) to socioeconomic and community information from the American Community Survey...
April 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28179220/modifiable-risk-factors-versus-age-on-developing-high-predicted-cardiovascular-disease-risk-in-blacks
#11
Adam P Bress, Lisandro D Colantonio, John N Booth, Tanya M Spruill, Joseph Ravenell, Mark Butler, Amanda J Shallcross, Samantha R Seals, Kristi Reynolds, Gbenga Ogedegbe, Daichi Shimbo, Paul Muntner
BACKGROUND: Clinical guidelines recommend using predicted atherosclerotic cardiovascular disease (ASCVD) risk to inform treatment decisions. The objective was to compare the contribution of changes in modifiable risk factors versus aging to the development of high 10-year predicted ASCVD risk. METHODS AND RESULTS: A prospective follow-up was done of the Jackson Heart Study, an exclusively black cohort at visit 1 (2000-2004) and visit 3 (2009-2012). Analyses included 1115 black participants without high 10-year predicted ASCVD risk (<7...
February 8, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27984005/treatment-resistant-hypertension-and-outcomes-based-on-randomized-treatment-group-in-allhat
#12
RANDOMIZED CONTROLLED TRIAL
Sripal Bangalore, Barry R Davis, William C Cushman, Sara L Pressel, Paul M Muntner, David A Calhoun, John B Kostis, Paul K Whelton, Jeffrey L Probstfield, Mahboob Rahman, Henry R Black
BACKGROUND: Although hypertension guidelines define treatment-resistant hypertension as blood pressure uncontrolled by ≥3 antihypertensive medications, including a diuretic, it is unknown whether patient prognosis differs when a diuretic is included. METHODS: Participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) were randomly assigned to first-step therapy with chlorthalidone, amlodipine, or lisinopril. At a Year 2 follow-up visit, those with average blood pressure ≥140 mm Hg systolic or ≥90 mm Hg diastolic on ≥3 antihypertensive medications, or blood pressure <140/90 mm Hg on ≥4 antihypertensive medications were identified as having apparent treatment-resistant hypertension...
April 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/27927632/associations-between-blood-pressure-and-outcomes-among-blacks-in-the-jackson-heart-study
#13
Tiffany C Randolph, Melissa A Greiner, Chidiebube Egwim, Adrian F Hernandez, Kevin L Thomas, Lesley H Curtis, Paul Muntner, Wei Wang, Robert J Mentz, Emily C O'Brien
BACKGROUND: In 2014, new hypertension guidelines liberalized blood pressure goals for persons 60 years and older. Little is known about the implications for blacks. METHODS AND RESULTS: Using data from 2000 through 2011 for 5280 participants in the Jackson Heart Study, a community-based black cohort in Jackson, Mississippi, we examined whether higher blood pressure was associated with greater risk of mortality and heart failure hospitalization, and whether the risk was the same across age groups...
December 7, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27787891/a-brief-dietary-assessment-predicts-executive-dysfunction-in-an-elderly-cohort-results-from-the-einstein-aging-study
#14
Erin E Sundermann, Mindy J Katz, Richard B Lipton, Alice H Lichtenstein, Carol A Derby
OBJECTIVES: To examine the association between diet and executive function, episodic memory and global verbal cognition in the Einstein Aging Study (EAS) cohort and determine whether race modifies this relationship. DESIGN: Cross-sectional. SETTING: Community. PARTICIPANTS: EAS participants without dementia who completed the Rapid Eating and Activity Assessment for Patients (REAP) (N = 492). MEASUREMENTS: The previously validated REAP is based on the 2000 U...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27756796/few-disparities-in-baseline-laboratory-testing-after-the-diuretic-or-digoxin-initiation-by-medicare-fee-for-service-beneficiaries
#15
MULTICENTER STUDY
Matthew L Maciejewski, Xiaojuan Mi, Lesley H Curtis, Judy Ng, Samuel C Haffer, Bradley G Hammill
BACKGROUND: Despite the persistence of significant disparities, few evaluations examine disparities in laboratory testing by race/ethnicity, age, sex, Medicaid eligibility, and number of chronic conditions for Medicare fee-for-service beneficiaries' newly prescribed medications. In Medicare beneficiaries initiating diuretics or digoxin, this study examined disparities in guideline-appropriate baseline laboratory testing and abnormal laboratory values. METHODS AND RESULTS: To evaluate guideline-concordant testing for serum creatinine and serum potassium within 180 days before or 14 days after the index prescription fill date, we constructed retrospective cohorts from 10 states of 99 711 beneficiaries who had heart failure or hypertension initiating diuretic in 2011 and 8683 beneficiaries who had heart failure or atrial fibrillation initiating digoxin...
November 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/27753810/ssa-04-1-similarities-and-differences-in-latin-american-guidelines-from-others
#16
Agustin Ramirez
The presentation will focus on the different guidelines we have actually in hands (JNCHT 8, ESH / ESC, ISH) and compare them to the last Latin-American Society of Hypertension Guidelines to be published in this year.In this way, we will focus our attention in the socio-economic problem of the different countries in LA and the differences we have included in our Guidelines due to the actual needs in LA.Additionally we will specially mention the special populations from LA like andineans, people living over 500m from sea level, and the different black populations that are different from those described in North America...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27693861/hypertension-treatment-in-blacks-discussion-of-the-u-s-clinical-practice-guidelines
#17
REVIEW
Stephen K Williams, Joseph Ravenell, Sara Seyedali, Sam Nayef, Gbenga Ogedegbe
Blacks are especially susceptible to hypertension (HTN) and its associated organ damage leading to adverse cardiovascular, cerebrovascular and renal outcomes. Accordingly, HTN is particularly significant in contributing to the black-white racial differences in health outcomes in the US. As such, in order to address these health disparities, practical clinical practice guidelines (CPGs) on how to treat HTN, specifically in blacks, are needed. This review article is a timely addition to the literature because the most recent U...
November 2016: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/27643326/ssa-04-1-similarities-and-differences-in-latin-american-guidelines-from-others
#18
Agustin Ramirez
The presentation will focus on the different guidelines we have actually in hands (JNCHT 8, ESH / ESC, ISH) and compare them to the last Latin-American Society of Hypertension Guidelines to be published in this year.In this way, we will focus our attention in the socio-economic problem of the different countries in LA and the differences we have included in our Guidelines due to the actual needs in LA.Additionally we will specially mention the special populations from LA like andineans, people living over 500m from sea level, and the different black populations that are different from those described in North America...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27621092/a-comparison-of-the-use-of-clinical-guideline-recommended-antihypertensive-regimens-in-mexican-american-non-hispanic-black-and-non-hispanic-white-adults-with-type-2-diabetes-and-hypertension-in-the-united-states-nhanes-2003-2012
#19
Alexandra Perez, Andrea Levin, Nowrin Alam
PURPOSE: The purpose of this study was to determine the use of clinical-guideline-recommended antihypertensive regimens among Mexican Americans (MAs) and non-Hispanic blacks and whites with type 2 diabetes and hypertension. METHODS: A secondary data analysis based on National Health and Nutrition Examination Survey 2003-2012 cohort data included 1857 noninstitutionalized civilian MA, black, and white adults with type 2 diabetes and hypertension. Unadjusted and adjusted 2-way analysis of variance models evaluated whether there was a difference in the use of recommended antihypertensive regimens across race/ethnic group...
September 12, 2016: Diabetes Educator
https://www.readbyqxmd.com/read/27587277/influence-of-age-and-race-on-24-hour-ambulatory-blood-pressure-responses-to-valsartan-hydrochlorothiazide-and-their-combination-implications-for-clinical-practice
#20
MULTICENTER STUDY
Joseph L Izzo, Yan Jia, Dion H Zappe
The effects of race and age on 24-hour mean ambulatory systolic blood pressure (maSBP) responses to sequential 4-week periods of angiotensin receptor blocker therapy (valsartan [VAL] 160 mg/d then 320 mg/d and combination VAL/hydrochlorothiazide [HCTZ] 320/12.5 mg/d) were compared in 304 patients with stage 1 or 2 hypertension. There were lesser blood pressure (BP) responses from baseline with VAL monotherapy in black than Caucasian patients (-2.9 and -4.0 mm Hg vs -8.2 and -9.3 mm Hg, respectively; P<.001 each) but VAL/HCTZ BP responses were similar in both groups (-12 vs -15 mm Hg)...
February 2017: Journal of Clinical Hypertension
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