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Maged Ragab, Mohamed G Soliman, Ahmed Tawfik, Ali Abdel Raheem, Hassan El-Tatawy, Mohamed Abo Farha, Michael Magdy, Osama Elashry
PURPOSE: To investigate the role of pregabalin in relieving USRS in patients with an indwelling double-J (DJ) stents. PATIENTS AND METHODS: A total of 500 adult patients with a unilateral single ureteral stone who underwent ureteroscopic stone management and required DJ stent insertion were prospectively included in our study. Patients were blindly assigned into four groups A, B, C and D. Those in group A were managed with combination of solifenacin 5-mg tablets and pregabalin 75-mg capsules bid...
March 4, 2017: International Urology and Nephrology
Yu-Ming Zhang, Pei Chu, Wen-Jin Wang
BACKGROUND: As a monotherpay, a-blockers and anti-muscarinics are both efficacy for ureteral stent-related symptoms (SRS). The aim of the study was to systematically evaluate their efficacy of a combination therapy for SRS. METHODS: Relevant studies investigating α-blockers and/or anti-muscarinics for SRS were identified though searching online databases including PubMed, EMBASE, Cochrane Library, and other sources up to March 2016. The RevMan software was used for data analysis, and senesitivity analysis and inverted funnel plot were also adopted...
February 2017: Medicine (Baltimore)
Athanasios E Dellis, Athanasios G Papatsoris, Francis X Keeley, Aristotelis Bamias, Charalambos Deliveliotis, Andreas A Skolarikos
PURPOSE: To properly use the Ureteric Symptom Score Questionnaire (USSQ) to evaluate, in a randomized control study, the effect of tamsulosin, solifenacin, and their combination in improving symptoms and quality of life in patients with indwelling ureteral stents. MATERIALS AND METHODS: After institutional review board approval, 260 patients with a ureteral stent were randomly assigned to receive tamsulosin 0.4 mg, solifenacin 5 mg, or placebo and further randomized to receive their combination...
January 2017: Journal of Endourology
Yiloren Tanidir, Naside Mangir, Ahmet Sahan, Muhammed Sulukaya
PURPOSE: Ureteric stents are frequently used in urology practice and can cause significant impairment in quality of life (QoL). The aim of this study was to validate the Ureteral Stent Symptoms Questionnaire (USSQ) to be used in the evaluation of stent-related symptoms and impairment in QoL in Turkish-speaking patients. METHODS: After linguistic validation of the original USSQ into Turkish language, the Turkish version of the USSQ (T-USSQ) was self-administered to all participants at week 1 and 4 after stent placement for test-retest reliability and internal consistency and at week 8 (4 weeks after stent removal) for sensitivity to change analysis...
October 20, 2016: World Journal of Urology
Huilei Yan, Yunhui Wang, Rong Sun, Yuanshan Cui
INTRODUCTION AND AIM: The purpose of this meta-analysis was to evaluate the efficacy of antimuscarinics alone or in combination with alpha-blockers for the treatment of ureteral stent-related symptoms. METHODS: The databases MEDLINE, EMBASE, PubMed, the Cochrane Controlled Trial Register of Controlled Trials from 2000 to February 2016 were searched to identify randomized controlled trials that referred to the use of a combination of antimuscarinics and alpha-blockers for the treatment of ureteral stent-related symptoms...
October 20, 2016: Urologia Internationalis
G Ordaz-Jurado, A Budía-Alba, P Bahilo-Mateu, J D López-Acón, M Trassierra-Villa, F Boronat-Tormo
OBJECTIVE: Double J ureteral stents are frequently used to allow free diuresis from the kidney to the bladder, but their presence has a major impact on patient's quality of life (QoL). Our aim is to describe such impact, and to describe possible solutions that can alleviate the symptoms associated with their use. METHODS: Systematic search in bibliographic sources including Cochrane library, UpToDate, Pubmed, Tripdatabase, selecting publications between 2000- 2015, and also the EAU European guidelines (2016)...
October 2016: Archivos Españoles de Urología
Franklin C Lee, Sarah K Holt, Ryan S Hsi, Brandon M Haynes, Jonathan D Harper
OBJECTIVE: To investigate whether the use of a belladonna and opium (B&O) rectal suppository administered immediately before ureteroscopy (URS) and stent placement could reduce stent-related discomfort. METHODS: A randomized, double-blinded, placebo-controlled study was performed from August 2013 to December 2014. Seventy-one subjects were enrolled and randomized to receive a B&O (15 mg/30 mg) or a placebo suppository after induction of general anesthesia immediately before URS and stent placement...
February 2017: Urology
Long Zhang, Junping Li, Minjie Pan, Weiwei Han, Shucheng Liu, Yajun Xiao
OBJECTIVE: To assess the impact of Doxazosin Oral Intake Therapy on urinary symptoms and pain in patients with indwelling ureteral stents Patients and Methods: A total of 239 patients with ureteral stone-related hydronephrosis who underwent a double-J stent insertion after ureteroscopic lithotripsy were enrolled. Patients were randomized to receive doxazosin cotrolled release 4 mg once daily for 4 weeks or matching placebo. Patients completed the brief-form Chinese version Ureteric Stent Symptom Questionnaire (USSQ) and quality of life (QoL) score 2 weeks and 4 weeks after stent placement and 4 weeks after stent withdrawal...
July 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Ashraf M Abdelaal, Ahmed M Al-Adl, Shabieb A Abdelbaki, Mohamed M Al Azab, Khaled A Al Gamal
OBJECTIVES: To evaluate the efficacy of solifenacin, tamsulosin oral-controlled absorption system (OCAS), and the combination of both drugs on JJ stent-related symptoms using the validated Arabic version of the ureteric stent symptom questionnaire (USSQ). PATIENTS AND METHODS: In all, 260 patients who had undergone JJ stenting of the ureter for different endoscopic urological procedures were postoperatively randomly assigned into four equal groups. Patients in Group I received no treatment and served as the control group, Group II patients received tamsulosin OCAS 0...
June 2016: Arab Journal of Urology
Dominik Abt, Kristina Dötzer, Patrick Honek, Karolina Müller, Daniel Stephan Engeler, Maximilian Burger, Hans-Peter Schmid, Thomas Knoll, Francesco Sanguedolce, Hrishi B Joshi, Hans-Martin Fritsche
PURPOSE: We developed and validated the German version of the Ureteral Stent Symptoms Questionnaire (USSQ) for male and female patients with indwelling ureteral stents. METHODS: The German version of the USSQ was developed following a well-established multistep process. A total of 101 patients with indwelling ureteral stents completed the German USSQ as well as the validated questionnaires International Prostate Symptom Score (IPSS) or International Consultation on Incontinence Questionnaire (ICIQ) and the Short Form Health Survey (SF-36)...
June 23, 2016: World Journal of Urology
Feng He, Li-Bo Man, Gui-Zhong Li, Ning Liu
OBJECTIVE: To critically evaluate the efficacy of an α-blocker in improving ureteral-stent-related symptoms and preliminarily investigate the difference between different types of α-blockers. METHODS: Relevant randomized controlled trials were identified through searching PubMed, the Cochrane Library, Embase, and other sources. After quality assessment and data abstraction, direct comparison based on the Ureteral Stent-related Symptom Questionnaire (USSQ) between α-blockers and control was performed by RevMan 5...
2016: Drug Design, Development and Therapy
Miguel Maldonado-Avila, Leopoldo Garduno-Arteaga, Rene Jungfermann-Guzman, Hugo A Manzanilla-Garcia, Emmanuel Rosas-Nava, Nestor Procuna-Hernandez, Alejandro Vela-Mollinedo, Luis Almazan-Trevino, Jose Guzman-Esquivel
INTRODUCTION AND OBJECTIVE: Indwelling double J ureteral stents are used routinely in the resolution of ureteral obstruction caused by different etiologies. Evaluation of urinary symptoms related to double-J stent, indicate that these affect 73-90% of patients. We conducted a prospective, randomized study, to evaluate the efficacy of tamsulosin, oxybutinin and combination therapy in improving the urinary symptoms. METHODS: Patients who underwent ureteral stent placement after ureterolithotripsy (total 51), were randomized into three groups: Group I: Tamsulosin 0...
May 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Peng Zhang, Wan-Li Hu, Bei Cheng, Long Cheng, Yang-Jun Zeng, Gang Wang
The present meta-analysis aimed to evaluate the current evidence for the use of α1-blockers in relieving ureteric stent-related symptoms (USS). Electronic databases, including PubMed, Embase and Cochrane Library, were searched and two independent reviewers identified relevant parallel randomized controlled trials (RCTs), assessed trial quality and extracted data. Review Manager (version 5.2) was used to conduct a meta-analysis of the data. Significant advantages were demonstrated in the treatment group based on International Prostate Symptom Score (IPSS), voiding symptom sub-scores [mean difference (MD), -2...
February 2016: Experimental and Therapeutic Medicine
Satinder Pal Aggarwal, Shivam Priyadarshi, Vinay Tomar, S S Yadav, Goto Gangkak, Nachiket Vyas, Neeraj Agarwal, Ujwal Kumar
Objectives. To evaluate the safety and efficacy of Tadalafil and Tamsulosin in treating Double J stent related symptoms. Methods. In a prospective study, 161 patients with DJ related symptoms were randomized into 3 groups: Group A patients (54), Group B patients (53), and Group C patients (54). They were given Tadalafil, Tamsulosin, and placebo, respectively, at 1st week till removal of DJ stent at 3rd week. All patients completed Ureteral Stent Symptom Questionnaire (USSQ) at 1st week and at 3rd week. The statistical significant difference among groups was determined by the t-test, Kruskal-Wallis test and multivariate analysis were used to assess association of the variables within the three groups, and the level of significance was set at P < 0...
2015: Advances in Urology
Ahmed R El-Nahas, Mohamed Tharwat, Mohamed Elsaadany, Ahmed Mosbah, Mohamed A Gaballah
PURPOSE: To compare the effectiveness of tamsulosin and solifenacin in relieving ureteral stents related symptoms. PATIENTS AND METHODS: A randomized controlled trial was conducted between January 2013 and July 2014. Inclusion criteria were patients aged 20-50 years who underwent temporary unilateral ureteral stent for drainage of calcular upper tract obstruction or after ureteroscopic lithotripsy. Patients with history of lower urinary tract symptoms before stent placement, stents that were fixed after open or laparoscopic procedures, and those who developed complications related to the primary procedure were not included...
July 2016: World Journal of Urology
Sri Sivalingam, Necole M Streeper, Priyanka D Sehgal, Brian C Sninsky, Sara L Best, Stephen Y Nakada
PURPOSE: Ureteral stent discomfort is a significant postoperative problem for many patients. Despite the use of narcotics and α-blockers patients often experience bothersome lower urinary tract symptoms and pain, which impair daily activities. We compared combination therapy with an α-blocker and an anticholinergic to monotherapy with an α-blocker. MATERIALS AND METHODS: A double-blind, randomized, controlled trial was performed from December 2012 to April 2014...
February 2016: Journal of Urology
Ahmed R El-Nahas, Mohamed M Elsaadany, Mohamed Tharwat, Ahmed Mosbah, Amr H Metwally, Amr Hawary, Francis X Keeley, Khaled Z Sheir
OBJECTIVE: To validate the Arabic version of the Ureteral Stent Symptoms Questionnaire (USSQ). PATIENTS AND METHODS: The English version of the USSQ was translated into Arabic using a multi-step process by three urologists and two independent translators. The Arabic version was validated by asking 37 patients with temporary unilateral ureteric stents to complete the questionnaire at 2 weeks after stent insertion. The second group included 53 healthy individuals who agreed to complete the Arabic version of the questionnaire...
December 2014: Arab Journal of Urology
Dominik Abt, Livio Mordasini, Elisabeth Warzinek, Hans-Peter Schmid, Sarah Roberta Haile, Daniel Stephan Engeler, Gautier Müllhaupt
PURPOSE: Temporary drainage of the upper urinary tract by use of internal ureteral stents is a common procedure that is often associated with a variety of symptoms. The role of intravesical stent position in associated morbidity is controversial. MATERIALS AND METHODS: The German version of the ureteral stent symptom questionnaire (USSQ) was completed by 73 patients with an indwelling ureteral stent the day before stent removal. Intravesical stent position was classified into 3 categories by x-ray before stent removal...
May 2015: Korean Journal of Urology
P Chiron, V Reslinger, R Haus, F-R Desfemmes, X Durand, Y Bayoud, B Molimard
OBJECTIVES: To evaluate the quality of life of the holders of a ureteral double J stent (US) using the USSQ questionnaire (Ureteral Stent Symptom Questionnaire), validated in French in 2010. METHODS: Between January 2009 and December 2011, 249 patients underwent flexible ureteroscopy for urolithiais in our service. Among them, 160 received a US in perioperative, and they were sent self-questionnaire USSQ-FR retrospectively. The questionnaire includes 38 questions, concerning the perioperative period with US, and 4 weeks after its removal, grouped into 6 sections: urinary symptoms, pain, general health, professional resounding, sexual resounding, and other problems...
June 2015: Progrès en Urologie
Jinsung Park, Changhee Yoo, Deok Hyun Han, Dong Wook Shin
OBJECTIVE: To assess the efficacy of tamsulosin, solifenacin, and combination therapy of both agents for the treatment of ureteral stent-related symptoms (SRSs). METHODS: An open-label, randomized controlled trial was conducted with 112 patients who underwent unilateral ureteral stent insertion following ureteroscopic stone surgery. Patients were randomized with a 2 × 2 factorial design to one of four groups, i.e., A (control), B (tamsulosin 0.2 mg once daily), C (solifenacin 5 mg once daily), and D (both active treatments)...
November 2015: World Journal of Urology
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