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Cervical cancer prevention

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https://www.readbyqxmd.com/read/29034685/improving-performance-on-preventive-health-quality-measures-using-clinical-decision-support-to-capture-care-done-elsewhere-and-patient-exceptions
#1
Michael E Bowen, Deepa Bhat, Jason Fish, Brett Moran, Temple Howell-Stampley, Lynne Kirk, Stephen D Persell, Ethan A Halm
Preventive services required for performance measurement often are completed in outside health systems and not captured in electronic medical records (EMRs). A before-after study was conducted to examine the ability of clinical decision support (CDS) to improve performance on preventive quality measures, capture clinician-reported services completed elsewhere, and patient/medical exceptions and to describe their impact on quality measurement. CDS improved performance on colorectal cancer screening, osteoporosis screening, and pneumococcal vaccination measures ( P < ...
October 1, 2017: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/29034117/correlates-of-cervical-cancer-screening-among-adult-latino-women-a-5-year-follow-up
#2
Patria Rojas, Tan Li, Gira J Ravelo, Christyl Dawson, Mariana Sanchez, Alicia Sneij, Weize Wang, Mariano Kanamori, Elena Cyrus, Mario R De La Rosa
BACKGROUND: Latinas have the highest incidence rates of cervical cancer in the United States, and Latinas in the United States are less likely to utilize cervical cancer screening. METHOD: We used secondary data analysis of a non-clinical convenience sample (n=316 women at baseline; n=285 at five-year follow-up) to examine correlates of cervical cancer screening among adult Latina women. Univariate and multiple logistic regression models using Generalized Estimated Equations (GEE) algorithm were utilized to assess the influence of the independent variables...
June 2017: World Medical & Health Policy
https://www.readbyqxmd.com/read/29031425/contents-of-japanese-pro-and-anti-hpv-vaccination-websites-a-text-mining-analysis
#3
Tsuyoshi Okuhara, Hirono Ishikawa, Masahumi Okada, Mio Kato, Takahiro Kiuchi
OBJECTIVE: In Japan, the human papillomavirus (HPV) vaccination rate has sharply fallen to nearly 0% due to sensational media reports of adverse events. Online anti-HPV-vaccination activists often warn readers of the vaccine's dangers. Here, we aimed to examine frequently appearing contents on pro- and anti-HPV vaccination websites. METHODS: We conducted online searches via two major search engines (Google Japan and Yahoo! Japan). Targeted websites were classified as "pro," "anti," or "neutral" according to their claims, with the author(s) classified as "health professionals," "mass media," or "laypersons...
September 23, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29029626/higher-educational-attainment-associated-with-reduced-likelihood-of-abnormal-cervical-lesions-among-zambian-women-a-cross-sectional-study
#4
Twaambo Euphemia Hamoonga, Rosemary Ndonyo Likwa, Patrick Musonda, Charles Michelo
BACKGROUND: The high burden of cervical cancer in Zambia prompted the Ministry of Health and partners to develop the cervical cancer prevention program in Zambia (CCPPZ) in 2006. Despite this intervention more women continue to die from the disease and there is little understanding of factors that may be linked with abnormal cervical lesions in the general population. We therefore examined if educational attainment is associated with abnormal cervical lesions among Zambian women aged 15 to 49 years...
October 13, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29027811/prevention-of-human-papillomavirus-hpv-related-tumors-in-people-living-with-human-immunodeficiency-virus-hiv
#5
Mario Poljak, Anja Šterbenc, Maja M Lunar
In comparison to their HIV-negative counterparts, people living with HIV (PLWH) have a higher prevalence of human papillomavirus (HPV) infection in various anatomical sites coupled with increased HPV persistence, higher risk of HPV-related tumors, and faster disease progression. Areas covered: Gender-neutral prevention strategies for HPV-related cancers in PLWH discussed: ABC approach, HPV vaccination, antiretroviral treatment (ART), anal cancer screening, and smoking cessation. Gender specific strategies: cervical cancer screening reduces the incidence and mortality of cervical cancer and circumcision might reduce the risk of HPV infections in men...
October 13, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/29025633/association-between-male-circumcision-and-women-s-biomedical-health-outcomes-a-systematic-review
#6
Jonathan M Grund, Tyler S Bryant, Inimfon Jackson, Kelly Curran, Naomi Bock, Carlos Toledo, Joanna Taliano, Sheng Zhou, Jorge Martin Del Campo, Ling Yang, Apollo Kivumbi, Peizi Li, Sherri Pals, Stephanie M Davis
BACKGROUND: Male circumcision reduces men's risk of acquiring HIV and some sexually transmitted infections from heterosexual exposure, and is essential for HIV prevention in sub-Saharan Africa. Studies have also investigated associations between male circumcision and risk of acquisition of HIV and sexually transmitted infections in women. We aimed to review all evidence on associations between male circumcision and women's health outcomes to benefit women's health programmes. METHODS: In this systematic review we searched for peer-reviewed and grey literature publications reporting associations between male circumcision and women's health outcomes up to April 11, 2016...
November 2017: Lancet Global Health
https://www.readbyqxmd.com/read/29025500/the-influence-of-self-efficacy-in-medical-drama-television-programming-on-behaviors-and-emotions-that-promote-cervical-cancer-prevention
#7
Sungsu Kim, Jay D Hmielowski
OBJECTIVES: We explored the influences of medical drama viewing on health behaviors and emotions, and examined the role of self-efficacy in medical drama programming. METHODS: A single-factor, 2-condition experimental design that manipulated self-efficacy levels was adopted. A total of 131 female undergraduate students who were likely involved with the issues of HPV vaccination and cervical cancer participated in this experiment. RESULTS: In line with social cognitive theory, the results indicated that participants in the high self-efficacy condition showed greater behavioral intention to receive a Pap smear (F (1, 126) = 4...
November 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29023986/evaluation-of-short-and-long-term-efficacy-of-chemoradiotherapy-for-advanced-cervical-cancer-using-hsp70-protein-combined-with-multimodal-mri
#8
Yun-Xiang Qi, Kun Liu, Jun Yin, Lu Li
This study aims to evaluate the efficacy of chemoradiotherapy for advanced cervical cancer using heat shock protein 70 (HSP70) combined with multimodal MRI. The protein expressions of HSP70 in biopsy specimens obtained from 101 patients with cervical cancer were detected by immunohistochemistry. Plain MRI scan, DWI, DCE-MR and MRS were performed before and after a period of six months of chemoradiotherapy. All patients were assigned into the complete response (CR) and partial response (PR) groups. HSP70 protein expression, tumor diameter and tumor volume were lower in the CR group than in the PR group...
October 11, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29023748/what-cervical-screening-is-appropriate-for-women-who-have-been-vaccinated-against-high-risk-hpv-a-simulation-study
#9
Rebecca Landy, Peter Windridge, Matthew S Gillman, Peter D Sasieni
Women vaccinated against HPV16/18 are approaching the age for cervical screening, however an updated screening algorithm has not been agreed. We use a microsimulation model calibrated to real published data to determine the appropriate screening intensity for vaccinated women. Natural histories in the absence of vaccination were simulated for 300,000 women using 10,000 sets of transition probabilities. Vaccination with i) 100% efficacy against HPV16/18, ii) 15% cross-protection, iii) waning vaccine efficacy, and iv) 100% efficacy against HPV16/18/31/33/45/52/58 was added, as were a range of screening scenarios appropriate to the UK...
October 11, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29020396/perception-and-use-of-pap-smear-screening-among-rural-and-urban-women-in-romania
#10
Mihaela Grigore, Razvan Popovici, Anda Pristavu, Ana Maria Grigore, Mioara Matei, Dumitru Gafitanu
Background: In 2012 the National Screening Program for all women between 25 and 64 years of age was launched in Romania. Public awareness is an important factor in the success of a screening program. For this reason, we intended to assess the perception and the level of awareness of Romanian women regarding the Pap test in the prevention of cervical cancer. Methods: A cross-sectional study was conducted among 454 women from rural and urban areas. For our study, we used a questionnaire covering general characteristics, awareness, knowledge and practices regarding cervical cancer and Pap smear...
August 4, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29020099/experiences-of-cervical-cancer-patients-in-rural-ghana-an-exploratory-study
#11
Charity Binka, David Teye Doku, Kofi Awusabo-Asare
Even though cervical cancer is quite a prevalent disease in Ghana, there is hardly any study on this disease. This paper sought to explore the experiences of cervical cancer patients living with the disease with emphasis on their knowledge about the disease before and after the diagnosis. Qualitative data were collected through in-depth interviews with cervical cancer patients undergoing treatment in a specialised cancer treatment health facility in rural Ghana. Cervical cancer patients had inadequate knowledge about the disease, its symptoms, risk factors, treatment and prevention prior to being diagnosed of the disease...
2017: PloS One
https://www.readbyqxmd.com/read/29016596/experiences-of-operational-costs-of-hpv-vaccine-delivery-strategies-in-gavi-supported-demonstration-projects
#12
Siobhan Botwright, Taylor Holroyd, Shreya Nanda, Paul Bloem, Ulla K Griffiths, Anissa Sidibe, Raymond C W Hutubessy
From 2012 to 2016, Gavi, the Vaccine Alliance, provided support for countries to conduct small-scale demonstration projects for the introduction of the human papillomavirus vaccine, with the aim of determining which human papillomavirus vaccine delivery strategies might be effective and sustainable upon national scale-up. This study reports on the operational costs and cost determinants of different vaccination delivery strategies within these projects across twelve countries using a standardized micro-costing tool...
2017: PloS One
https://www.readbyqxmd.com/read/28990460/amplification-of-specific-chromosomal-regions-assessed-by-fluorescent-in-situ-hybridization-on-pap-smears-to-be-added-as-screening-tool-for-identifying-women-at-risk-of-progressing-to-cervical-cancer
#13
Pavani Upendram, Shubhi Sahni, Khaliq Mohiuddin, Subhadra Poornima, Bhanumathy Gourishankar, Kiran Kumar Vattam, Pavani Boddala, E Jayashankar, Shakera Mohiuddin, Vasundhara Kamineni, Vasavi Mohan, Jane Houldsworth, Qurratulain Hasan
Cervical carcinoma is a frequent malignancy in developing countries despite being a preventable disease. For the first time, four screening tests were used simultaneously for identifying women with a risk of developing cervical cancer, to help clinicians and policy makers to implement the best strategy for reducing the burden of this disease. Women visiting a hospital in India were enrolled after institutional ethics clearance and informed consent. Visual inspection using acetic acid and Pap smear tests were performed on 2683 women, and 104 had abnormal cytology: atypical squamous cells of undetermined significance (n = 29), low-grade squamous intraepithelial lesion (n = 41), high-grade squamous intraepithelial lesion (n = 17), and squamous cell carcinoma (n = 17)...
October 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28989018/optimization-of-a-vaginal-suppository-formulation-to-deliver-sheta2-as-a-novel-treatment-for-cervical-dysplasia
#14
Sanjida Mahjabeen, Manolya K Hatipoglu, Vishal Chandra, Doris M Benbrook, Lucila Garcia-Contreras
Cervical dysplasia induced by the human papilloma virus (HPV) unpredictably progresses to cervical cancer. Therapeutic options are invasive and affect the patient's quality of life. SHetA2 has demonstrated therapeutic efficacy against human and murine HPV- induced tumors, but its oral bioavailability is <1%. An optimized vaginal suppository formulation can deliver SHetA2 in sufficient doses to prevent cervical dysplasia. The quality by design (QbD) approach was employed to optimize the suppository formulation consisting of cocoa butter as base with 5% Kolliphor and 40% SHetA2...
October 5, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28988647/secondary-prevention-of-cervical-cancer
#15
REVIEW
Partha Basu, Srabani Mittal, Diama Bhadra Vale, Youssef Chami Kharaji
Cervical cancer affects women in their reproductive ages. Screening is an important secondary prevention strategy. The long process of carcinogenic transformation from human papillomavirus (HPV) infection to invasive cancer provides ample opportunities to detect the disease at a stage when treatment is highly effective. Suitable screening tests are cytology, visual inspection after acetic acid application and HPV detection tests. Evidence of effectiveness of the tests to reduce cervical cancer mortality and the cost-effectiveness of screening programs have been demonstrated...
September 6, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28986659/hpv-vaccination-in-japan-results-of-a-3-year-follow-up-survey-of-obstetricians-and-gynecologists-regarding-their-opinions-toward-the-vaccine
#16
Masaaki Sawada, Yutaka Ueda, Asami Yagi, Akiko Morimoto, Ruriko Nakae, Reisa Kakubari, Hazuki Abe, Tomomi Egawa-Takata, Tadashi Iwamiya, Shinya Matsuzaki, Eiji Kobayashi, Kiyoshi Yoshino, Tadashi Kimura
BACKGROUND: In Japan, the cervical cancer preventative HPV vaccination rate has dramatically declined, directly as a result of repeated broadcasts of so-called adverse events and the resulting suspension of the government's recommendation. Our previous survey of obstetricians and gynecologists in Japan regarding their opinions toward HPV vaccination revealed that these key specialists were as negatively influenced by the reports of purported negative events as were the general population...
October 6, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28986092/population-based-hpv-vaccination-programmes-are-safe-and-effective-2017-update-and-the-impetus-for-achieving-better-global-coverage
#17
REVIEW
Julia M L Brotherton, Paul N Bloem
Persistent oncogenic human papillomavirus (HPV) is the cause of cervical cancer, as well as cancers of the anus, penis, vulva, vagina and oropharynx. There is good evidence that prophylactic HPV vaccines are immunogenic and effective against targeted-type HPV infections and type-specific genital lesions, including high-grade cervical intraepithelial neoplasia (CIN), when administered prior to HPV infection. There is good evidence that HPV vaccines are safe in population usage, with the most frequent adverse event being injection-site reactions...
September 6, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28985169/cervical-cancer-in-african-american-women-optimizing-prevention-to-reduce-disparities
#18
EDITORIAL
Anita D Misra-Hebert
No abstract text is available yet for this article.
October 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28983579/cost-effectiveness-of-two-dose-human-papillomavirus-vaccination-in-singapore
#19
Sun Kuie Tay, Bee-Wah Lee, Woo Yun Sohn, I-Heng Lee, Gaurav Mathur, Melvin Sanicas, Georges Van Kriekinge
INTRODUCTION: Cervical cancer is the tenth most common cancer and the eighth most frequent cause of death among women in Singapore. Human papillomavirus (HPV) infection is the necessary cause of cervical cancer and therefore the risk of cervical cancer can be substantially reduced through vaccination. This study was conducted to evaluate the cost-effectiveness of two-dose HPV vaccination, as part of a national vaccination programme for 12-year-old girls in Singapore, from the perspective of the healthcare payer...
October 6, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28983400/human-papillomavirus-vaccination-uptake-in-canada-a-systematic-review-and-meta-analysis
#20
REVIEW
Yelena Bird, Olatunji Obidiya, Razi Mahmood, Chijioke Nwankwo, John Moraros
Human papillomavirus (HPV) is the most commonly sexually transmitted infection in the world and the primary cause of cervical cancer. Canada introduced publicly funded HPV vaccination programs in 2006. The objectives of this study are twofold and aim to (1) determine the levels and (2) examine the various factors influencing vaccine uptake among the general Canadian population. A literature search was conducted on seven databases, followed by screening, methodological quality review (using modified Newcastle-Ottawa Scale), and data extraction...
2017: International Journal of Preventive Medicine
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