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https://www.readbyqxmd.com/read/29773245/validation-of-an-open-source-tool-for-measuring-carotid-lumen-diameter-and-intima-media-thickness
#1
Hugo Luis Manterola, Lucas Lo Vercio, Alejandro Díaz, Mariana Del Fresno, Ignacio Larrabide
In low- and middle-income regions, a relatively large number of deaths occur from cardiovascular disease or stroke. Carotid intima-media thickness (cIMT) and carotid lumen diameter (cLD) are strong indicators of cardiovascular event risk and stenosis severity, respectively. The interactive open-source software described here, Cimtool, is based on active contours for measuring these indicators in clinical practice and thus helping in preventive diagnosis and treatment. Cimtool was validated using carotid phantoms and real images obtained using ultrasound...
May 14, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29772872/spatial-analysis-for-the-epidemiological-study-of-cardiovascular-diseases-a-systematic-literature-search
#2
Carlos Mena, Cesar Sepúlveda, Eduardo Fuentes, Yony Ormazábal, Iván Palomo
Cardiovascular diseases (CVDs) are the primary cause of death and disability in de world, and the detection of populations at risk as well as localization of vulnerable areas is essential for adequate epidemiological management. Techniques developed for spatial analysis, among them geographical information systems and spatial statistics, such as cluster detection and spatial correlation, are useful for the study of the distribution of the CVDs. These techniques, enabling recognition of events at different geographical levels of study (e...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29770445/cost-effectiveness-of-a-community-based-diabetes-prevention-program-with-participation-incentives-for-medicaid-beneficiaries
#3
Todd Gilmer, Patrick J O'Connor, Jeffrey S Schiff, Gretchen Taylor, Gabriela Vazquez-Benitez, Joyce E Garrett, Houa Vue-Her, Sarah Rinn, Julie Anderson, Jay Desai
OBJECTIVE: To examine the cost-effectiveness of a community-based Diabetes Prevention Program (DPP) for Medicaid beneficiaries from the perspective of the health care sector. DATA SOURCES/STUDY SETTING: A total of 847 Medicaid enrollees at high risk for type 2 diabetes participating in a community-based DPP. STUDY DESIGN: Pre- and post clinical outcome and cost data were used as inputs into a validated diabetes simulation model. The model was used to evaluate quality-adjusted life years (QALYs) and health care costs over a 40-year time horizon from the perspective of the health care sector...
May 16, 2018: Health Services Research
https://www.readbyqxmd.com/read/29765104/falls-and-recurrent-falls-among-adults-in-a-multi-ethnic-asian-population-the-singapore-epidemiology-of-eye-diseases-study
#4
Wei Dai, Yih-Chung Tham, Miao-Li Chee, Nicholas Y Q Tan, Kah-Hie Wong, Shivani Majithia, Charumathi Sabanayagam, Ecosse Lamoureux, Tien-Yin Wong, Ching-Yu Cheng
We evaluated the rate and risk factors associated with falls and recurrent falls in a multi-ethnic Asian population. 10,009 participants aged ≥40 years (mean[SD] age = 58.9[10.4] years) underwent clinical examinations and completed interviewer-administered questionnaires. Participants who self-reported at least one fall or ≥2 falls in past 12 months were defined as fallers and recurrent fallers, respectively. Age-standardized rates for falls and recurrent falls were 13.8% (95%CI, 13.1-14.6%) and 4.6% (95%CI, 4...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29760227/socioeconomic-status-and-cardiovascular-outcomes-challenges-and-interventions
#5
REVIEW
William M Schultz, Heval M Kelli, John C Lisko, Tina Varghese, Jia Shen, Pratik Sandesara, Arshed A Quyyumi, Herman A Taylor, Martha Gulati, John G Harold, Jennifer H Mieres, Keith C Ferdinand, George A Mensah, Laurence S Sperling
Socioeconomic status (SES) has a measurable and significant effect on cardiovascular health. Biological, behavioral, and psychosocial risk factors prevalent in disadvantaged individuals accentuate the link between SES and cardiovascular disease (CVD). Four measures have been consistently associated with CVD in high-income countries: income level, educational attainment, employment status, and neighborhood socioeconomic factors. In addition, disparities based on sex have been shown in several studies. Interventions targeting patients with low SES have predominantly focused on modification of traditional CVD risk factors...
May 15, 2018: Circulation
https://www.readbyqxmd.com/read/29757315/a-multi-center-prospective-cohort-study-to-evaluate-the-effect-of-differential-pricing-and-health-systems-strengthening-on-access-to-medicines-and-management-of-hypertension-and-diabetes-in-ghana-a-study-protocol
#6
Linda Meta Mobula, Stephen Sarfo, Lynda Arthur, Gilbert Burnham, Jacob Plange-Rhule, Daniel Ansong, Edith Gavor, David Ofori-Adjei
Background: There is evidence to suggest that the prevalence of non-communicable diseases (NCDs), in particular cardiovascular diseases and diabetes, are being recognized as forming a substantial proportion of the burden of disease among populations in Low- and Middle-Income Countries (LMICs).  Access to treatment is likely a key barrier to the control and prevention of NCD outcomes.  Differential pricing, an approach used to price drugs based on the purchasing power of patients in different socioeconomic segments, has been shown to be beneficial and leads to improved access and affordability...
February 7, 2018: Gates open research
https://www.readbyqxmd.com/read/29752699/hiv-and-cardiovascular-disease-update-on-clinical-events-special-populations-and-novel-biomarkers
#7
REVIEW
Kaku So-Armah, Matthew S Freiberg
PURPOSE OF REVIEW: The objective of this review is to provide an update on the link between HIV infection and cardiovascular disease (CVD). We will focus our review mainly on literature describing clinical CVD events and understudied topics of importance. RECENT FINDINGS: Heart failure, peripheral artery disease, and stroke are CVD modalities deserving more attention in the context of HIV infection in the highly active antiretroviral therapy era. Incidence data on clinical CVD from HIV populations in low- and middle-income countries are limited...
May 11, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29742584/predictive-validity-of-sepsis-3-definitions-and-sepsis-outcomes-in-critically-ill-patients-a-cohort-study-in-49-icus-in-argentina
#8
Elisa Estenssoro, Vanina S Kanoore Edul, Cecilia I Loudet, Javier Osatnik, Fernando G Ríos, Daniela N Vázquez, Mario O Pozo, Bernardo Lattanzio, Fernando Pálizas, Francisco Klein, Damián Piezny, Paolo N Rubatto Birri, Graciela Tuhay, Anatilde Díaz, Analía Santamaría, Graciela Zakalik, Arnaldo Dubin
OBJECTIVES: The new Sepsis-3 definitions have been scarcely assessed in low- and middle-income countries; besides, regional information of sepsis outcomes is sparse. Our objective was to evaluate Sepsis-3 definition performance in Argentina. DESIGN: Cohort study of 3-month duration beginning on July 1, 2016. SETTINGS: Forty-nine ICUs. PATIENTS: Consecutive patients admitted to the ICU with suspected infection that triggered blood cultures and antibiotic administration...
May 8, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29731441/out-of-pocket-oop-cost-of-treating-hypertension-in-karachi-pakistan
#9
Nousheen Aslam, Muhammad Harris Shoaib, Rabia Bushra, Faraz Ahmed Farooqi, Farya Zafar, Huma Ali, Saima Saleem
Pakistan is categorized to below to middle income countries where two third of the national annual health expenditure is in the form of out of pocket (OOP) cost. A prevalence based study was conducted to determine the OOP cost treatment of hypertension in Karachi by interviewing 350 hypertensive patients aged >30 years through a validated questionnaire. Hypertension (HTN) was classified into stage 1 and stage 2 and was found to be common in females (53.42%) than males (46.57%). The total costs of stage 1and stage 2 HTN were calculated to be 217869...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29731256/antiretroviral-therapy-potentiates-high-fat-diet-induced-obesity-and-glucose-intolerance
#10
Mark E Pepin, Lindsey E Padgett, Ruth E McDowell, Ashley R Burg, Manoja K Brahma, Cassie Holleman, Teayoun Kim, David Crossman, Olaf Kutsch, Hubert M Tse, Adam R Wende, Kirk M Habegger
OBJECTIVE: Breakthroughs in HIV treatment, especially combination antiretroviral therapy (ART), have massively reduced AIDS-associated mortality. However, ART administration amplifies the risk of non-AIDS defining illnesses including obesity, diabetes, and cardiovascular disease, collectively known as metabolic syndrome. Initial reports suggest that ART-associated risk of metabolic syndrome correlates with socioeconomic status, a multifaceted finding that encompasses income, race, education, and diet...
April 20, 2018: Molecular Metabolism
https://www.readbyqxmd.com/read/29720359/diffusion-of-the-digital-health-self-tracking-movement-in-canada-results-of-a-national-survey
#11
Guy Paré, Chad Leaver, Claire Bourget
BACKGROUND: With the ever-increasing availability of mobile apps, consumer wearables, and smart medical devices, more and more individuals are self-tracking and managing their personal health data. OBJECTIVE: The aim of this study was to investigate the diffusion of the digital self-tracking movement in Canada. It provides a comprehensive, yet detailed account of this phenomenon. It examines the profile of digital self-trackers, traditional self-trackers, and nontrackers, further investigating the primary motivations for self-tracking and reasons for nontracking; barriers to adoption of connected care technologies; users' appreciation of their self-tracking devices, including what they perceive to be the main benefits; factors that influence people's intention to continue using connected care technologies in the future; and the reasons for usage discontinuance...
May 2, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29719966/external-validity-of-a-cardiovascular-screening-including-a-coronary-artery-calcium-examination-in-middle-aged-individuals-from-the-general-population
#12
Mette H Grønhøj, Oke Gerke, Hans Mickley, Flemming H Steffensen, Jess Lambrechtsen, Niels Peter R Sand, Lars M Rasmussen, Michael H Olsen, Jesper Hallas, Axel Cp Diederichsen
Background Coronary artery calcium is important in cardiovascular risk stratification, but this knowledge is based on studies with a significant selection bias. This study aims to evaluate the external validity of a screening programme including coronary artery calcium examination, and the association between coronary artery calcium and cardiovascular events. Design Multi-centre population based study. Methods Randomly selected middle-aged men and women ( N = 1751) free of cardiovascular disease were invited to the examination during 2009-2010...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29713618/relationship-between-nutrition-intake-and-estimated-glomerular-filtration-rate-in-korean-adults-30-65-years-from-the-korea-national-health-and-nutrition-examination-survey-2013-2014
#13
Jihye Ryu, So Ra Yoon, Won Suk An, Oh Yoen Kim
This study aimed to examine the relationship between nutrition intake and estimated glomerular filtration rate (eGFR) indicating kidney function in Korean individuals without diabetes or cardiovascular disease. Study participants from the Korea National Health and Nutrition Examination Survey 2013-2014 (n = 4,378, 30-65 years) were classified by their eGFR levels (mL/min/1.732 m2 ): ≥ 120 (n = 299), 119-105 (n = 789), 104-90 (n = 1,578), 89-60 (n = 1,685), < 60 (n = 27). After adjusted for confounding factors (age, sex, cigarette smoking, alcohol drinking, total caloric intake [TCI], income status, education level, body mass index, and physical activity), blood pressure, low-density lipoprotein (LDL) cholesterol, aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen, creatinine, fasting glucose, and glycated hemoglobin were higher, and high density lipoprotein cholesterol levels were lower in participants with lower eGFR levels than those with higher eGFR levels...
April 2018: Clinical Nutrition Research
https://www.readbyqxmd.com/read/29712712/impact-of-healthy-lifestyle-factors-on-life-expectancies-in-the-us-population
#14
Yanping Li, An Pan, Dong D Wang, Xiaoran Liu, Klodian Dhana, Oscar H Franco, Stephen Kaptoge, Emanuele Di Angelantonio, Meir Stampfer, Walter C Willett, Frank B Hu
Background -Americans have a shorter life expectancy compared with residents of almost all other high-income countries. We aim to estimate the impact of lifestyle factors on premature mortality and life expectancy in the US population. Methods -Using data from the Nurses' Health Study (1980-2014; n=78 865) and the Health Professionals Follow-up Study (1986-2014, n=44 354), we defined 5 low-risk lifestyle factors as never smoking, body mass index of 18.5 to 24.9 kg/m2 , ≥30 min/d of moderate to vigorous physical activity, moderate alcohol intake, and a high diet quality score (upper 40%), and estimated hazard ratios for the association of total lifestyle score (0-5 scale) with mortality...
April 30, 2018: Circulation
https://www.readbyqxmd.com/read/29706397/cardiovascular-risk-goes-up-as-your-mood-goes-down-interaction-of-depression-and-socioeconomic-status-in-determination-of-cardiovascular-risk-in-the-constances-cohort
#15
Emmanuel Wiernik, Pierre Meneton, Jean-Philippe Empana, Jack Siemiatycki, Nicolas Hoertel, Hélène Vulser, Hermann Nabi, Frédéric Limosin, Sébastien Czernichow, Marcel Goldberg, Anna Ozguler, Marie Zins, Cédric Lemogne
BACKGROUND: Recent evidence suggests that the association of psychological variables with the risk of coronary heart disease (CHD) might depend upon socioeconomic status (SES). However, it is unclear whether the association between depressive symptoms and CHD risk might differ according to three SES indicators (education, occupational status and household monthly income). METHODS: Among 34,836 working participants of the French CONSTANCES cohort (16,221 men, mean age [SD]: 44...
July 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29704370/evaluation-of-healthy-fit-a-community-health-worker-model-to-address-hispanic-health-disparities
#16
Louis D Brown, Denise Vasquez, Jennifer J Salinas, Xiaohui Tang, Hector Balcázar
INTRODUCTION: Hispanics in the United States have disproportionately high rates of obesity, hypertension, and diabetes and poorer access to preventive health services. Healthy Fit uses community health workers to extend public health department infrastructure and address Hispanic health disparities related to cardiovascular disease and access to preventive health services. We evaluated the effectiveness of Healthy Fit in 1) reaching Hispanic Americans facing health disparities, and 2) helping participants access preventive health services and make behavior changes to improve heart health...
April 26, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29700071/defining-the-human-envirome-an-omics-approach-for-assessing-the-environmental-risk-of-cardiovascular-disease
#17
REVIEW
Daniel W Riggs, Ray A Yeager, Aruni Bhatnagar
Both genetic and environmental factors contribute to the development of cardiovascular disease, but in comparison with genetics, environmental factors have received less attention. Evaluation of environmental determinants of cardiovascular disease is limited by the lack of comprehensive omics approaches for integrating multiple environmental exposures. Hence, to understand the effects of the environment as a whole (envirome), it is important to delineate specific domains of the environment and to assess how, individually and collectively; these domains affect cardiovascular health...
April 27, 2018: Circulation Research
https://www.readbyqxmd.com/read/29688759/relations-between-the-residential-fast-food-environment-and-the-individual-risk-of-cardiovascular-diseases-in-the-netherlands-a-nationwide-follow-up-study
#18
Maartje Poelman, Maciej Strak, Oliver Schmitz, Gerard Hoek, Derek Karssenberg, Marco Helbich, Anna-Maria Ntarladima, Michiel Bots, Bert Brunekreef, Rick Grobbee, Martin Dijst, Ilonca Vaartjes
Background The food environment has been hypothesized to influence cardiovascular diseases such as hypertension and coronary heart disease. This study determines the relation between fast-food outlet density (FFD) and the individual risk for cardiovascular disease, among a nationwide Dutch sample. Methods After linkage of three national registers, a cohort of 2,472,004 adults (≥35 years), free from cardiovascular disease at January 1st 2009 and living at the same address for ≥15 years was constructed. Participants were followed for one year to determine incidence of cardiovascular disease, including coronary heart disease, stroke and heart failure...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29688733/drug-use-for-secondary-prevention-of-cardiovascular-diseases-in-golestan-iran-results-from-the-golestan-cohort-study
#19
Mahdi Nalini, Sadaf G Sepanlou, Akram Pourshams, Hossein Poustchi, Maryam Sharafkhah, Hossein Bahrami, Farin Kamangar, Reza Malekzadeh
BACKGROUND: Little is known about secondary prevention of cardiovascular diseases, using cardio-protective drugs, in the community-level, especially in low- and middle-income countries. We aimed to assess main drug use and its predictors in Northeast of Iran. METHODS: This is a cross-sectional analysis on the Golestan Cohort Study data (2004-2008) with 50 045 participants. We assessed drug use in those with a history of ischemic heart disease (IHD) or stroke, recorded by face-to-face interviews...
March 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29688297/ten-year-association-of-coronary-artery-calcium-with-atherosclerotic-cardiovascular-disease-ascvd-events-the-multi-ethnic-study-of-atherosclerosis-mesa
#20
Matthew J Budoff, Rebekah Young, Gregory Burke, J Jeffrey Carr, Robert C Detrano, Aaron R Folsom, Richard Kronmal, Joao A C Lima, Kiang J Liu, Robyn L McClelland, Erin Michos, Wendy S Post, Steven Shea, Karol E Watson, Nathan D Wong
Aims: While coronary artery calcium (CAC) has been extensively validated for predicting clinical events, most outcome studies of CAC have evaluated coronary heart disease (CHD) rather than atherosclerotic cardiovascular disease (ASCVD) events (including stroke). Also, virtually all CAC studies are of short- or intermediate-term follow-up, so studies across multi-ethnic cohorts with long-term follow-up are warranted prior to widespread clinical use. We sought to evaluate the contribution of CAC using the population-based MESA cohort with over 10 years of follow-up for ASCVD events, and whether the association of CAC with events varied by sex, race/ethnicity, or age category...
April 23, 2018: European Heart Journal
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