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https://www.readbyqxmd.com/read/28635374/sepsis-favors-high-on-clopidogrel-platelet-reactivity
#1
Karolina Akinosoglou, Angelos Perperis, Spyridoula Theodoraki, Dimitrios Alexopoulos, Charalambos Gogos
High-on-treatment platelet reactivity (HPR) is associated with ischemic events in patients on antiplatelet therapy with a history of cardiovascular disease. On the other hand, recent data have associated sepsis with adverse cardiovascular events in patients admitted with bacteremia or respiratory infection. We aimed to assess P2Y12-mediated platelet reactivity (PR) during sepsis and recovery in patients under clopidogrel. This was a prospective observational study. Incoming patients presenting with signs/symptoms of sepsis already on a maintenance dose of clopidogrel of 75 mg qd for cardiovascular events were included in this study...
June 21, 2017: Platelets
https://www.readbyqxmd.com/read/28633392/can-estimation-of-sodium-intake-be-improved-by-borrowing-information-from-other-variables
#2
Lawrence J Appel, David R Jacobs
Estimation of dietary sodium intake is problematic. The most accurate measure is average sodium excretion from multiple 24 hour urine collections, but such an approach is impractical. Using data from the Women's Health Initiative, Prentice and colleagues assessed the relationship of calibrated estimates of sodium and potassium excretion with cardiovascular outcomes. The calibrated estimates are a function of self-reported sodium/potassium ratio from a food frequency questionnaire, age, body mass index, race, supplement use, smoking status, education, income, and aspirin use...
June 14, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28629640/is-physical-activity-a-modifier-of-the-association-between-air-pollution-and-arterial-stiffness-in-older-adults-the-sapaldia-cohort-study
#3
Simon Endes, Emmanuel Schaffner, Seraina Caviezel, Julia Dratva, Daiana Stolz, Christian Schindler, Nino Künzli, Arno Schmidt-Trucksäss, Nicole Probst-Hensch
INTRODUCTION AND OBJECTIVES: Air pollution and insufficient physical activity have been associated with inflammation and oxidative stress, molecular mechanisms linked to arterial stiffness and cardiovascular disease. There are no studies on how physical activity modifies the association between air pollution and arterial stiffness. We examined whether the adverse cardiovascular effects of air pollution were modified by individual physical activity levels in 2823 adults aged 50-81 years from the well-characterized Swiss Cohort Study on Air Pollution and Lung and Heart Diseases (SAPALDIA)...
June 13, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28629279/understanding-determinants-of-cardiovascular-health-in-a-mexican-american-community
#4
Karen A Larimer, Meg Gulanick, Sue Penckofer
Cardiovascular disease (CVD) is the leading cause of death in Hispanic Americans. Social and physical determinants of health unique to this community must be understood before interventions can be designed and implemented. This article describes a CVD risk assessment conducted in a primarily Mexican American community, using Healthy People 2020 as a model. Social (language, culture, awareness of CVD, and socio-economic status) and physical (presence and use of recreation areas, presence of grocery stores, public transportation, and environmental pollution) determinants of health as well as access to health services were assessed...
July 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28625084/objectively-assessed-physical-activity-and-associated-factors-of-sedentary-behavior-among-survivors-of-stroke-living-in-cape-town-south-africa
#5
Conran Joseph, David Conradsson, Maria Hagströmer, Isa Lawal, Anthea Rhoda
PURPOSE: To investigate objectively measured physical activity in stroke survivors living in low-income areas of Cape Town, South Africa, specifically to: (a) describe the volume of daily physical activity and time spent in different intensity levels and (b) investigate the association of factors covering the International Classification of Functioning, Disability and Health with sedentary behavior. MATERIALS AND METHODS: A cross-sectional design was used, where forty-five ambulatory community-dwelling stroke survivors participated...
June 18, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28619699/the-relationship-between-blood-pressure-and-sleep-duration-in-turkish-children-a-cross-sectional-study
#6
Cengiz Bal, Ahmet Öztürk, Betül Çiçek, Ahmet Özdemir, Gökmen Zararsız, Demet Ünalan, Gözde Ertürk Zararsız, Selçuk Korkmaz, Dinçer Göksülük, Vahap Eldem, Sevda İsmailoğulları, Emine Erdem, Mümtaz M Mazıcıoğlu, Selam Kurtoğlu
OBJECTIVE: As in adults, hypertension is also an important risk factor for cardiovascular disease in children. We aimed to evaluate the effect of sleep duration on blood pressure in normal weight Turkish children aged between 11-17 years. METHODS: This cross-sectional study was conducted in the primary and secondary schools of the two central and ten outlying districts of Kayseri/Turkey with 2860 (1385 boys, 1475 girls) children and adolescents. Systolic and diastolic blood pressures were measured according to the recommendations of the Fourth Report of the National High Blood Pressure Education Program (NHBPEP) Working Group on High Blood Pressure in Children and Adolescents...
June 16, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28618914/role-of-the-polypill-for-secondary-prevention-in-ischaemic-heart-disease
#7
José M Castellano, Valentín Fuster, Catriona Jennings, Eva Prescott, Héctor Bueno
In 2011, for the first time in the history of humankind, non-communicable diseases became the leading cause of death worldwide. This change in trend is obviously multifactorial and very complex, as it is the paradoxical result of social, economic and health system growth worldwide. Vaccination and infectious diseases control, changing dietary habits worldwide, sedentary behaviour, globalisation, industrialisation (resulting in a shift from manual to sedentary labour), tobacco and sugary beverage surges in low- and middle-income countries and rapid urbanisation have all played a role in this epidemic transition...
June 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28618906/quality-assurance-and-the-need-to-evaluate-interventions-and-audit-programme-outcomes
#8
Min Zhao, Ilonca Vaartjes, Kerstin Klipstein-Grobusch, Kornelia Kotseva, Catriona Jennings, Diederick E Grobbee, Ian Graham
Evidence-based clinical guidelines provide standards for the provision of healthcare. However, these guidelines have been poorly implemented in daily practice. Clinical audit is a quality improvement tool to promote quality of care in daily practice and to improve outcomes through the systematic review of care delivery and implementation of changes. A major priority in the management of subjects with cardiovascular disease (CVD) management is secondary prevention by controlling cardiovascular risk factors and providing appropriate medical treatment...
June 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28617662/telomere-length-and-accelerated-biological-aging-in-the-china-suboptimal-health-cohort-a-case-control-study
#9
Mohamed Ali Alzain, Collins Otieno Asweto, Jie Zhang, Honghong Fang, Zhongyao Zhao, Xiuhua Guo, Manshu Song, Yong Zhou, Naibai Chang, Youxin Wang, Wei Wang
Suboptimal health status (SHS) has been linked to cardiovascular risk factors, psychosocial stress, and unhealthy lifestyle. These factors also contribute to the shortening of telomere length (TL). A case-control study was conducted to examine the association between subjective health measures of SHS from the behavior perspective and also objective measures of TL at molecular level. SHS (cases = 294) was matched by age, sex, and body mass index with ideal health (controls = 294) using a propensity score matching method...
June 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28614469/assessing-the-feasibility-of-the-healthy-life-in-suriname-study-using-advanced-hemodynamics-to-evaluate-cardiovascular-risk
#10
Jet Q Aartman, Frederieke S Diemer, Fares A Karamat, Evelien Bohte, Sergio M Baldew, Ameerani V Jarbandhan, Gert A van Montfrans, Glenn P Oehlers, Lizzy M Brewster
Objectives: To determine the feasibility of assessing population cardiovascular risk with advanced hemodynamics in the Healthy Life in Suriname (HELISUR) study. Methods: This was a preliminary study conducted in May - June 2012 using the Technical-Economic-Legal-Operational-Scheduling (TELOS) method to assess the feasibility of the HELISUR-a large-scale, cross-sectional population study of cardiovascular risk factors and disease in Suriname. Suriname, a middle-income country in South America with a population of mostly African and Asian ethnicity, has a high risk of cardiovascular disease...
June 8, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28614461/-improved-blood-pressure-control-to-reduce-cardiovascular-disease-morbidity-and-mortality-the-standardized-hypertension-treatment-and-prevention-project
#11
Pragna Patel, Pedro Ordunez, Donald DiPette, María Cristina Escobar, Trevor Hassell, Fernando Wyss, Anselm Hennis, Samira Asma, Sonia Angell
Hypertension is the leading remediable risk factor for cardiovascular disease, affecting more than 1 billion people worldwide, and is responsible for more than 10 million preventable deaths globally each year. While hypertension can be successfully diagnosed and treated, only one in seven persons with hypertension have controlled blood pressure. To meet the challenge of improving the control of hypertension, particularly in low- and middle-income countries, the authors developed the Standardized Hypertension Treatment and Prevention Project, which involves a health systems-strengthening approach that advocates for standardized hypertension management using evidence-based interventions...
June 8, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28608758/a-systematic-narrative-review-of-the-effectiveness-of-behavioural-smoking-cessation-interventions-in-selected-disadvantaged-groups-2010-2017
#12
Amanda Wilson, Ashleigh Guillaumier, Johnson George, Alexandra Denham, Billie Bonevski
Tobacco remains the key modifiable risk factor for the development of a number of diseases, including cardiovascular disease, cerebrovascular disease, lower respiratory infections, chronic obstructive pulmonary disease, tuberculosis and cancer. Among priority populations, smoking prevalence remains high, smokers tend to relapse more often and earlier and fewer are able to sustain quit attempts. This systematic review provides an update on the literature. Areas covered: Twenty-four randomized controlled trials published from 2010-2017, in English language, were identified after searching on Medline, Ovid, Embase and PsycINFO databases...
June 21, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28606699/integrated-assessment-of-exposure-to-pm2-5-in-south-india-and-its-relation-with-cardiovascular-risk-design-of-the-chai-observational-cohort-study
#13
Cathryn Tonne, Maëlle Salmon, Margaux Sanchez, V Sreekanth, Santhi Bhogadi, Sankar Sambandam, Kalpana Balakrishnan, Sanjay Kinra, Julian D Marshall
While there is convincing evidence that fine particulate matter causes cardiovascular mortality and morbidity, little of the evidence is based on populations outside of high income countries, leaving large uncertainties at high exposures. India is an attractive setting for investigating the cardiovascular risk of particles across a wide concentration range, including concentrations for which there is the largest uncertainty in the exposure-response relationship. CHAI is a European Research Council funded project that investigates the relationship between particulate air pollution from outdoor and household sources with markers of atherosclerosis, an important cardiovascular pathology...
June 3, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28606184/multicomponent-intervention-versus-usual-care-for-management-of-hypertension-in-rural-bangladesh-pakistan-and-sri-lanka-study-protocol-for-a-cluster-randomized-controlled-trial
#14
Tazeen H Jafar, Imtiaz Jehan, H Asita de Silva, Aliya Naheed, Mihir Gandhi, Pryseley Assam, Eric A Finkelstein, Helena Legido Quigley, Marcel Bilger, Aamir Hameed Khan, John David Clemens, Shah Ebrahim, Elizabeth L Turner, Anuradhani Kasturiratne
BACKGROUND: High blood pressure (BP) is the leading attributable risk for cardiovascular disease (CVD). In rural South Asia, hypertension continues to be a significant public health issue with sub-optimal BP control rates. The goal of the trial is to compare a multicomponent intervention (MCI) to usual care to evaluate the effectiveness and cost-effectiveness of the MCI for lowering BP among adults with hypertension in rural communities in Bangladesh, Pakistan and Sri Lanka. METHODS/DESIGN: This study is a stratified, cluster randomized controlled trial with a qualitative component for evaluation of processes and stakeholder feedback...
June 12, 2017: Trials
https://www.readbyqxmd.com/read/28604921/association-of-educational-attainment-with-lifetime-risk-of-cardiovascular-disease-the-atherosclerosis-risk-in-communities-study
#15
Yasuhiko Kubota, Gerardo Heiss, Richard F MacLehose, Nicholas S Roetker, Aaron R Folsom
Importance: Estimates of lifetime risk may help raise awareness of the extent to which educational inequalities are associated with risk of cardiovascular disease (CVD). Objective: To estimate lifetime risks of CVD according to categories of educational attainment. Design, Setting, and Participants: Participants were followed from 1987 through December 31, 2013. All CVD events (coronary heart disease, heart failure, and stroke) were confirmed by physician review and International Classification of Diseases codes...
June 12, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28602543/reduction-in-cardiovascular-risk-among-latino-participants-in-a-community-based-intervention-linked-with-clinical-care
#16
Mori J Krantz, Brenda Beaty, Stephanie Coronel-Mockler, Bonnie Leeman-Castillo, Kelly Fletcher, Raymond O Estacio
INTRODUCTION: Community Heart Health Actions for Latinos at Risk is a community health worker-led cardiovascular disease risk reduction program targeting low-income urban Latinos. The impact of community programs linked with clinical care has not been well characterized. METHODS: Community Heart Health Actions for Latinos at Risk provided 12 weeks of lifestyle education. Changes in risk factors were assessed before and after completion. Univariate, bivariate, and multivariate analyses were used to determine factors associated with changes in risk factors...
June 8, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28600490/treating-tobacco-dependence-guidance-for-primary-care-on-life-saving-interventions-position-statement-of-the-ipcrg
#17
O C P Van Schayck, S Williams, V Barchilon, N Baxter, M Jawad, P A Katsaounou, B J Kirenga, C Panaitescu, K W I G Tsiligianni, N Zwar, A Ostrem
Tobacco smoking is the world's leading cause of premature death and disability. Global targets to reduce premature deaths by 25% by 2025 will require a substantial increase in the number of smokers making a quit attempt, and a significant improvement in the success rates of those attempts in low, middle and high income countries. In many countries the only place where the majority of smokers can access support to quit is primary care. There is strong evidence of cost-effective interventions in primary care yet many opportunities to put these into practice are missed...
June 9, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28600362/social-epidemiology-of-hypertension-in-buffalo-city-metropolitan-municipality-bcmm-cross-sectional-study-of-determinants-of-prevalence-awareness-treatment-and-control-among-south-african-adults
#18
Eyitayo Omolara Owolabi, Daniel Ter Goon, Oladele Vincent Adeniyi, Eunice Seekoe
OBJECTIVES: This study examined hypertension prevalence, awareness, treatment and control and their determinants among adults attending health facilities in Buffalo City Metropolitan Municipality (BCMM) in the Eastern Cape. DESIGN: A cross-sectional analytical study. SETTINGS: The three largest outpatient clinics in BCMM. PARTICIPANTS: Ambulatory adults (aged 18 years and over) attending the study settings during the study period (n=998)...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28597853/depression-and-physical-noncommunicable-diseases-the-need-for-an-integrated-approach
#19
Nazneen Anwar, Pooja Patnaik Kuppili, Yatan Pal Singh Balhara
Depression is globally the third-leading cause of disability in terms of disability-adjusted life-years. Depression in patients with diseases such as cancer, diabetes mellitus, stroke or cardiovascular disease is 2-4-fold more prevalent than in people who do not have physical noncommunicable diseases, and may have a more prolonged course. The significant burden due to depression that is comorbid with chronic physical disease, coupled with limited resources, makes it a major public health challenge for low- and middle-income countries...
April 2017: WHO South-East Asia Journal of Public Health
https://www.readbyqxmd.com/read/28595698/marfan-syndrome-and-quality-of-life-in-the-gentac-registry
#20
Judith Z Goldfinger, Liliana R Preiss, Richard B Devereux, Mary J Roman, Tabitha P Hendershot, Barbara L Kroner, Kim A Eagle
BACKGROUND: Previous small studies suggested reduced quality of life (QOL) for people with Marfan syndrome (MFS) compared with those without MFS. The national registry of GenTAC (Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions) is a longitudinal observational cohort study of patients with conditions that predispose to thoracic aortic aneurysms and dissections, including MFS. At the time of registry enrollment, GenTAC study participants are asked to complete questionnaires about demographics, medical history, health habits, and QOL...
June 13, 2017: Journal of the American College of Cardiology
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