keyword
MENU ▼
Read by QxMD icon Read
search

sotirchos

keyword
https://www.readbyqxmd.com/read/27672169/safety-and-immunologic-effects-of-high-vs-low-dose-cholecalciferol-in-multiple-sclerosis
#1
Daniel Kantor, Elias S Sotirchos, Peter A Calabresi
No abstract text is available yet for this article.
September 27, 2016: Neurology
https://www.readbyqxmd.com/read/27468837/erratum-to-pharmacokinetics-safety-and-efficacy-of-chemoembolization-with-doxorubicin-loaded-tightly-calibrated-small-microspheres-in-patients-with-hepatocellular-carcinoma
#2
Katerina Malagari, Theodoros Kiakidis, Maria Pomoni, Hippokratis Moschouris, Emmanouil Emmanouil, Themis Spiridopoulos, Vlasios Sotirchos, Savvas Tandeles, Dimitrios Koundouras, Alexios Kelekis, Dimitrios Filippiadis, Angelos Charokopakis, Evanthia Bouma, Achilles Chatziioannou, Spyridon Dourakis, John Koskinas, Theodoros Karampelas, Konstantinos Tamvakopoulos, Nikolaos Kelekis, Dimitrios Kelekis
No abstract text is available yet for this article.
July 28, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27462040/safety-and-immunologic-effects-of-high-vs-low-dose-cholecalciferol-in-multiple-sclerosis
#3
Daniel Golan, Ariel Miller, Elias S Sotirchos, Pavan Bhargava, Peter A Calabresi
No abstract text is available yet for this article.
July 26, 2016: Neurology
https://www.readbyqxmd.com/read/27462039/safety-and-immunologic-effects-of-high-vs-low-dose-cholecalciferol-in-multiple-sclerosis
#4
Jagannadha Avasarala, Elias S Sotirchos, Pavan Bhargava, Peter A Calabresi
No abstract text is available yet for this article.
July 26, 2016: Neurology
https://www.readbyqxmd.com/read/27393274/pharmacokinetics-safety-and-efficacy-of-chemoembolization-with-doxorubicin-loaded-tightly-calibrated-small-microspheres-in-patients-with-hepatocellular-carcinoma
#5
Katerina Malagari, Theodoros Kiakidis, Maria Pomoni, Hippokratis Moschouris, Emmanouil Emmanouil, Themis Spiridopoulos, Vlasios Sotirchos, Savvas Tandeles, Dimitrios Koundouras, Alexios Kelekis, Dimitrios Filippiadis, Angelos Charokopakis, Evanthia Bouma, Achilles Chatziioannou, Spyridon Dourakis, John Koskinas, Theodoros Karampelas, Konstantinos Tamvakopoulos, Nikolaos Kelekis, Dimitrios Kelekis
PURPOSE: This study examines safety, efficacy, and pharmacokinetics of chemoembolization with loadable microspheres ≤100 μm for hepatocellular carcinoma. MATERIALS AND METHODS: A pilot safety study was performed in 19 patients with size and dose escalation and then 52 patients were enrolled prospectively and randomly assigned to chemoembolization with TANDEM™ loaded with 150 or 100 mg of doxorubicin. RESULTS: The mean diameter of the tumors was 7...
October 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27384594/surrogate-imaging-biomarkers-of-response-of-colorectal-liver-metastases-after-salvage-radioembolization-using-90y-loaded-resin-microspheres
#6
Waleed Shady, Vlasios S Sotirchos, Richard K Do, Neeta Pandit-Taskar, Jorge A Carrasquillo, Mithat Gonen, Constantinos T Sofocleous
OBJECTIVE: The purpose of the present study is to evaluate Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1, tumor attenuation criteria, Choi criteria, and European Organization for Research and Treatment of Cancer (EORTC) PET criteria as measures of response and subsequent predictors of liver progression-free survival (PFS) after radioembolization (RE) of colorectal liver metastases (CLM). The study also assesses interobserver variability for measuring tumor attenuation using a single 2D ROI on a simple PACS workstation...
September 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27228089/intestinal-perforation-in-renal-transplant-recipients-a-single-center-experience-of-2123-recipients
#7
Kyriaki Kakavia, Demetrios Moris, Elli Karatza, John Bokos, Spiridon Vernadakis, Alexandros Barlas, Georgios Sotirchos, Konstantinos Diles, Spyridon Drakopoulos, Georgios Zavos
OBJECTIVES: Intestinal perforation remains a clinical challenge and potentially lethal complication in renal transplant recipients. Immunosuppression not only places the patient at risk for intestinal perforation but also masks classic clinical symptoms and signs of acute abdominal pain, leading to delayed diagnosis and proper treatment. The aim of our study is to present the experience of our center on the treatment of intestinal perforation in renal transplant recipients. MATERIALS AND METHODS: This study reported 11 patients (0...
May 26, 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27010254/colorectal-cancer-liver-metastases-biopsy-of-the-ablation-zone-and-margins-can-be-used-to-predict-oncologic-outcome
#8
Vlasios S Sotirchos, Lydia M Petrovic, Mithat Gönen, David S Klimstra, Richard K G Do, Elena N Petre, Alessandra R Garcia, Afsar Barlas, Joseph P Erinjeri, Karen T Brown, Anne M Covey, William Alago, Lynn A Brody, Ronald P DeMatteo, Nancy E Kemeny, Stephen B Solomon, Katia O Manova-Todorova, Constantinos T Sofocleous
Purpose To establish the prognostic value of biopsy of the central and marginal ablation zones for time to local tumor progression (LTP) after radiofrequency (RF) ablation of colorectal cancer liver metastasis (CLM). Materials and Methods A total of 47 patients with 67 CLMs were enrolled in this prospective institutional review board-approved and HIPAA-compliant study between November 2009 and August 2012. Mean tumor size was 2.1 cm (range, 0.6-4.3 cm). Biopsy of the center and margin of the ablation zone was performed immediately after RF ablation (mean number of biopsy samples per ablation zone, 1...
September 2016: Radiology
https://www.readbyqxmd.com/read/26912433/18f-fdg-pet-ct-is-an-immediate-imaging-biomarker-of-treatment-success-after-liver-metastasis-ablation
#9
Francois Cornelis, Vlasios Storchios, Elena Violari, Constantinos T Sofocleous, Heiko Schoder, Jeremy C Durack, Robert H Siegelbaum, Majid Maybody, John Humm, Stephen B Solomon
UNLABELLED: The rationale of this study was to examine whether (18)F-FDG PET/CT and contrast-enhanced CT performed immediately after percutaneous ablation of liver metastases are predictors of local treatment failure at 1 y. METHODS: This Health Insurance Portability and Accountability Act-compliant, Institutional Review Board-approved retrospective study reviewed 25 PET/CT-guided thermal ablations performed from September 2011 to March 2013 on 21 patients (11 women and 10 men; mean age, 56...
July 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/26718578/safety-and-immunologic-effects-of-high-vs-low-dose-cholecalciferol-in-multiple-sclerosis
#10
RANDOMIZED CONTROLLED TRIAL
Elias S Sotirchos, Pavan Bhargava, Christopher Eckstein, Keith Van Haren, Moira Baynes, Achilles Ntranos, Anne Gocke, Lawrence Steinman, Ellen M Mowry, Peter A Calabresi
OBJECTIVE: To study the safety profile and characterize the immunologic effects of high- vs low-dose cholecalciferol supplementation in patients with multiple sclerosis (MS). METHODS: In this double-blind, single-center randomized pilot study, 40 patients with relapsing-remitting MS were randomized to receive 10,400 IU or 800 IU cholecalciferol daily for 6 months. Assessments were performed at baseline and 3 and 6 months. RESULTS: Mean increase of 25-hydroxyvitamin D levels from baseline to final visit was larger in the high-dose group (34...
January 26, 2016: Neurology
https://www.readbyqxmd.com/read/26277696/radioembolization-as-a-salvage-therapy-for-heavily-pretreated-patients-with-colorectal-cancer-liver-metastases-factors-that-affect%C3%A2-outcomes
#11
Constantinos T Sofocleous, Elena G Violari, Vlasios S Sotirchos, Waleed Shady, Mithat Gonen, Neeta Pandit-Taskar, Elena N Petre, Lynn A Brody, William Alago, Richard K Do, Michael I D'Angelica, Joseph R Osborne, Neil H Segal, Jorge A Carrasquillo, Nancy E Kemeny
BACKGROUND: In this study we assessed the efficacy and factors that affect outcomes of radioembolization (RE) using yttrium-90 resin microspheres in patients with unresectable and chemorefractory colorectal cancer liver metastases (CLM). PATIENTS AND METHODS: After an institutional review board waiver of approval, a review of a Health Insurance Portability and Accountability Act-registered, prospectively created and maintained database was performed. Data on patient demographic and disease characteristics, RE treatment parameters, and additional treatments were evaluated for significance in predicting overall survival (OS) and liver progression-free survival (LPFS)...
December 2015: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/25609766/relationships-between-quantitative-spinal-cord-mri-and-retinal-layers-in-multiple-sclerosis
#12
Jiwon Oh, Elias S Sotirchos, Shiv Saidha, Anna Whetstone, Min Chen, Scott D Newsome, Kathy Zackowski, Laura J Balcer, Elliot Frohman, Jerry Prince, Marie Diener-West, Daniel S Reich, Peter A Calabresi
OBJECTIVE: To assess relationships between spinal cord MRI (SC-MRI) and retinal measures, and to evaluate whether these measures independently relate to clinical disability in multiple sclerosis (MS). METHODS: One hundred two patients with MS and 11 healthy controls underwent 3-tesla brain and cervical SC-MRI, which included standard T1- and T2-based sequences and diffusion-tensor and magnetization-transfer imaging, and optical coherence tomography with automated segmentation...
February 17, 2015: Neurology
https://www.readbyqxmd.com/read/25580316/safe-and-successful-yttrium-90-resin-microsphere-radioembolization-in-a-heavily-pretreated-patient-with-chemorefractory-colorectal-liver-metastases-after-biliary-stent-placement-above-the-papilla
#13
Vlasios S Sotirchos, Elena N Petre, Karen T Brown, Lynn A Brody, Michael I D'Angelica, Ronald P DeMatteo, Nancy E Kemeny, Constantinos T Sofocleous
We report a case of safe and successful yttrium-90 resin microsphere radioembolization in a patient with a long history of multiple recurrent colon cancer hepatic metastases progressing after hepatic resections, hepatic arterial chemotherapy, and multiple regimens of systemic chemotherapy. One month prior to radioembolization, a biliary stent was placed above the level of the ampulla to relieve tumor-related biliary obstruction and normalize bilirubin levels.
2014: Case Reports in Hepatology
https://www.readbyqxmd.com/read/25382184/retinal-damage-and-vision-loss-in-african-american-multiple-sclerosis-patients
#14
MULTICENTER STUDY
Dorlan J Kimbrough, Elias S Sotirchos, James A Wilson, Omar Al-Louzi, Amy Conger, Darrel Conger, Teresa C Frohman, Shiv Saidha, Ari J Green, Elliot M Frohman, Laura J Balcer, Peter A Calabresi
OBJECTIVE: To determine whether African American (AA) multiple sclerosis (MS) patients exhibit more retinal damage and visual impairment compared to Caucasian American (CA) MS patients. METHODS: A total of 687 MS patients (81 AAs) and 110 healthy control (HC) subjects (14 AAs) were recruited at 3 academic hospitals between 2008 and 2012. Using mixed effects regression models, we compared high- and low-contrast visual acuity (HCVA and LCVA) and high-definition spectral domain optical coherence tomography measures of retinal architecture between MS patients of self-identified AA and CA ancestry...
February 2015: Annals of Neurology
https://www.readbyqxmd.com/read/24893707/cerebrospinal-fluid-ceramides-from-patients-with-multiple-sclerosis-impair-neuronal-bioenergetics
#15
MULTICENTER STUDY
Oscar G Vidaurre, Jeffery D Haines, Ilana Katz Sand, Kadidia P Adula, Jimmy L Huynh, Corey A McGraw, Fan Zhang, Merina Varghese, Elias Sotirchos, Pavan Bhargava, Veera Venkata Ratnam Bandaru, Giulio Pasinetti, Weijia Zhang, Matilde Inglese, Peter A Calabresi, Gang Wu, Aaron E Miller, Norman J Haughey, Fred D Lublin, Patrizia Casaccia
Axonal damage is a prominent cause of disability and yet its pathogenesis is incompletely understood. Using a xenogeneic system, here we define the bioenergetic changes induced in rat neurons by exposure to cerebrospinal fluid samples from patients with multiple sclerosis compared to control subjects. A first discovery cohort of cerebrospinal fluid from 13 patients with multiple sclerosis and 10 control subjects showed that acute exposure to cerebrospinal fluid from patients with multiple sclerosis induced oxidative stress and decreased expression of neuroprotective genes, while increasing expression of genes involved in lipid signalling and in the response to oxidative stress...
August 2014: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/24593281/spinal-cord-normalization-in-multiple-sclerosis
#16
Jiwon Oh, Michaela Seigo, Shiv Saidha, Elias Sotirchos, Kathy Zackowski, Min Chen, Jerry Prince, Marie Diener-West, Peter A Calabresi, Daniel S Reich
BACKGROUND: Spinal cord (SC) pathology is common in multiple sclerosis (MS), and measures of SC-atrophy are increasingly utilized. Normalization reduces biological variation of structural measurements unrelated to disease, but optimal parameters for SC volume (SCV)-normalization remain unclear. Using a variety of normalization factors and clinical measures, we assessed the effect of SCV normalization on detecting group differences and clarifying clinical-radiological correlations in MS...
November 2014: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/24443687/deformable-registration-of-macular-oct-using-a-mode-scan-similarity
#17
Min Chen, Andrew Lang, Elias Sotirchos, Howard S Ying, Peter A Calabresi, Jerry L Prince, Aaron Carass
Optical coherence tomography (OCT) of the macular cube has become an increasingly important tool for investigating and managing retinal pathology. One important new area of investigation is the analysis of anatomic variably across a population. Such an analysis on the retina requires the construction of a normalized space, which is generally created through deformable registration of each subject into a common template. Unfortunately, state-of-the-art 3D registration tools fail to adequately spatially normalize retinal OCT images...
December 31, 2013: Proceedings of the IEEE International Symposium on Biomedical Imaging: from Nano to Macro
https://www.readbyqxmd.com/read/24263774/chemoembolization-of-hepatocellular-carcinoma-with-hepasphere-30-60-%C3%AE-m-safety-and-efficacy-study
#18
Katerina Malagari, Maria Pomoni, Hippokratis Moschouris, Alexios Kelekis, Angelos Charokopakis, Evanthia Bouma, Themistoklis Spyridopoulos, Achilles Chatziioannou, Vlasios Sotirchos, Theodoros Karampelas, Constantin Tamvakopoulos, Dimitrios Filippiadis, Enangelos Karagiannis, Athanasios Marinis, John Koskinas, Dimitrios A Kelekis
BACKGROUND: This study examined the safety, pharmacokinetics, and efficacy of transarterial chemoembolization of hepatocellular carcinoma (HCC) using a newly developed size of a superabsorbent polymer drug-eluting embolic material. METHODS: Forty-five patients with documented HCC (Child-Pugh score A/B: 55.5 %/44.5 %) were embolized with HepaSphere microspheres 30-60 μm with escalation of lesion, dose, and frequency of re-embolization. Local response was evaluated with modified response evaluation criteria in solid tumors (mRECIST)...
February 2014: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/23933933/long-term-recurrence-analysis-post-drug-eluting-bead-deb-chemoembolization-for-hepatocellular-carcinoma-hcc
#19
Katerina Malagari, Mary Pomoni, Vlasis S Sotirchos, Hippokratis Moschouris, Evanthia Bouma, Angelos Charokopakis, Alexios D Kelekis, Dimitrios Koundouras, Dimitris Filippiadis, Achilles Chatziioannou, Evangelos Karagiannis, Loukas Thanos, Efthymia Alexopoulou, Anastasia Pomoni, Spyridon Dourakis, Dimitrios A Kelekis
UNLABELLED: BACKROUND-AIMS: To determine long term outcomes, regarding recurrence and survival, in patients with HCC that achieved complete response after initial treatment with drug eluting beads (DEB) using DC Bead loaded with doxorubicin (DEB-DOX). METHODOLOGY: Forty-five patients with HCC, not suitable for curative treatments that exhibited complete response (EASL criteria) to initial DEB-DOX treatment were retrospectively analyzed after a median follow up period of 63 months...
September 2013: Hepato-gastroenterology
https://www.readbyqxmd.com/read/23847738/retinal-layer-segmentation-of-macular-oct-images-using-boundary-classification
#20
Andrew Lang, Aaron Carass, Matthew Hauser, Elias S Sotirchos, Peter A Calabresi, Howard S Ying, Jerry L Prince
Optical coherence tomography (OCT) has proven to be an essential imaging modality for ophthalmology and is proving to be very important in neurology. OCT enables high resolution imaging of the retina, both at the optic nerve head and the macula. Macular retinal layer thicknesses provide useful diagnostic information and have been shown to correlate well with measures of disease severity in several diseases. Since manual segmentation of these layers is time consuming and prone to bias, automatic segmentation methods are critical for full utilization of this technology...
July 1, 2013: Biomedical Optics Express
keyword
keyword
110146
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"