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https://www.readbyqxmd.com/read/29161182/alcohol-biomarkers-associated-with-obstructive-sleep-apnea
#1
R Gregory Lande, Cynthia T Gragnani, Miriam Pourzand, Despina Hangemanole
The views expressed in this presentation are those of the author and do not reflect the official policy of the Department of the Army/Navy/Air Force or the Department of Defense The identification of specific products or scientific instrumentation does not constitute an endorsement or implied endorsement on the part of the authors, DoD, or any component agency. While we generally excise references to products, companies, manufacturers, organizations, etc. in government produced works, the abstracts produced and other similarly situated researchers presents a special circumstance when such product inclusions become an integral part of the scientific endeavor...
November 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29160410/fuzzy-computational-models-to-evaluate-the-effects-of-air-pollution-on-children
#2
Gleise Silva David, Paloma Maria Silva Rocha Rizol, Luiz Fernando Costa Nascimento
OBJECTIVE: To build a fuzzy computational model to estimate the number of hospitalizations of children aged up to 10 years due to respiratory conditions based on pollutants and climatic factors in the city of São José do Rio Preto, Brazil. METHODS: A computational model was constructed using the fuzzy logic. The model has 4 inputs, each with 2 membership functions generating 16 rules, and the output with 5 pertinence functions, based on the Mamdani's method, to estimate the association between the pollutants and the number of hospitalizations...
November 13, 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29160103/integration-site-analysis-in-gene-therapy-patients-expectations-and-reality
#3
Luca Biasco
Integration site analysis is one of the major tools for addressing the safety of gene therapy clinical protocols based on the use of integrating vectors. Over the past years, the study of viral insertions in gene therapy treated patients has allowed identifying insertional mutagenesis events, evaluating the safety of new viral vector platforms and tracking the in vivo clonal dynamics of genetically engineered cell products. While gene therapy is progressively expanding its impact on a broader area of clinical applications, increasingly more accessible, faster and more reliable safety readouts are required from integration site analysis...
November 21, 2017: Human Gene Therapy
https://www.readbyqxmd.com/read/29159876/work-related-injuries-in-the-alaska-logging-industry-1991-2014
#4
Yuri P Springer, Devin L Lucas, Louisa J Castrodale, Joseph B McLaughlin
BACKGROUND: Although loggers in Alaska are at high risk for occupational injury, no comprehensive review of such injuries has been performed since the mid-1990s. We investigated work-related injuries in the Alaska logging industry during 1991-2014. METHODS: Using data from the Alaska Trauma Registry and the Alaska Occupational Injury Surveillance System, we described fatal and nonfatal injuries by factors including worker sex and age, timing and geographic location of injuries, and four injury characteristics...
November 21, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29159857/methylphenidate-for-children-and-adolescents-with-autism-spectrum-disorder
#5
REVIEW
Nancy Sturman, Laura Deckx, Mieke L van Driel
BACKGROUND: Children with autistic spectrum disorder (ASD) frequently present with inattention, impulsivity and hyperactivity, which are the cardinal symptoms of attention deficit hyperactivity disorder (ADHD). The effectiveness of methylphenidate, a commonly used ADHD treatment, is therefore of interest in these children. OBJECTIVES: To assess the effects of methylphenidate for symptoms of ADHD (inattention, impulsivity and hyperactivity) and ASD (impairments in social interaction and communication, and repetitive, restricted or stereotypical behaviours) in children and adolescents aged 6 to 18 years with ASD...
November 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29159520/moral-dilemmas-of-community-pharmacists-a-narrative-study
#6
Martine Kruijtbosch, Wilma Göttgens-Jansen, Annemieke Floor-Schreudering, Evert van Leeuwen, Marcel L Bouvy
Background Pharmacists are increasingly involved in patient care. This new role in a complex healthcare system with demanding patients may lead to moral dilemmas. There has been little research into pharmacy ethics, and existing data are limited by their retrospective nature and small sample sizes. A thematic overview of the moral dilemmas experienced by community pharmacists is still missing. Objective To make a thematic overview of moral dilemmas experienced in daily pharmacy practice. Setting Dutch community pharmacy...
November 20, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29159243/data-on-people-s-interests-related-to-entry-into-the-chinese-market-based-on-internet-activity-corresponding-to-real-world-statistical-data-in-the-period-2004-2015-in-japan
#7
Weiren Fan, Tomohisa Ueda, Yoshimasa Sagane
This data article describes Internet activities in Japan related to entry into the Chinese market from 2004 to 2015 using data obtained from mining Google Trends. The search volumes were processed and correlated with statistical annual data on the number of Chinese companies founded by investment from Japanese companies. Relative search volumes generated by Google Trends reflect the increase and decrease in the number of Chinese companies founded by Japanese companies in the "real world." The correlation between relative search volumes generated by Google Trends and foundation of companies in the "real world" in the study period (2004-2015) was statistically significant...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29159242/data-on-spatiotemporal-patterns-of-the-foundation-of-japanese-companies-in-china-from-1980-2016
#8
Weiren Fan, Tomohisa Ueda, Yoshimasa Sagane
This data article provides spatiotemporal patterns of the foundation of Japanese companies in China. The data for companies in the food manufacturing, wholesaling, and service industries were collected from published lists of Chinese companies founded through the investment of Japanese companies. The data are provided in a matrix heatmap format, a two-dimensional visualization of data using color to represent the magnitude of two variables: year of foundation and area in China where the company is located.
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29158816/dual-targeting-theranostic-system-with-mimicking-apoptosis-to-promote-myocardial-infarction-repair-via-modulation-of-macrophages
#9
Jingli Chen, Jun Yang, Ruiyuan Liu, Chenmeng Qiao, Zhiguo Lu, Yuanjie Shi, Zhanming Fan, Zhenzhong Zhang, Xin Zhang
Currently unsatisfactory treatment of myocardial infarction (MI) is due to the unbridled inflammation and the delayed diagnosis at the early stage. To address these problems, firstly, phosphatidylserine (PS) was used to modulate the phenotypes of macrophages (MΦ) and resolve the early inflammation via binding to PS receptors (PSR) on macrophage surface. Secondly, highly-sensitive magnetic iron oxide nanocubes (MIONs) were adopted to realize the early visualization via magnetic resonance imaging (MRI). However, the major drawback for MIONs as contrast agents was their hydrophobic properties and insufficient delivery...
2017: Theranostics
https://www.readbyqxmd.com/read/29158209/shaping-an-effective-health-information-website-on-rare-diseases-using-a-group-decision-making-tool-inclusion-of-the-perspectives-of-patients-their-family-members-and-physicians
#10
Ana Babac, Svenja Litzkendorf, Katharina Schmidt, Frédéric Pauer, Kathrin Damm, Martin Frank, Johann-Matthias Graf von der Schulenburg
BACKGROUND: Despite diverging definitions on rare conditions, people suffering from rare diseases share similar difficulties. A lack of experience by health professionals, a long wait from first symptoms to diagnosis, scarce medical and scientific knowledge, and unsatisfactory treatment options all trigger the search for health information by patients, family members, and physicians. Examining and systematically integrating stakeholder needs can help design information platforms that effectively support this search...
November 20, 2017: Interactive Journal of Medical Research
https://www.readbyqxmd.com/read/29157624/language-specific-strategy-for-programming-hearing-aids-a-double-blind-randomized-controlled-crossover-study
#11
Nozomu Matsumoto, Nobuyoshi Suzuki, Satoshi Iwasaki, Kazuha Ishikawa, Hiroki Tsukiji, Yoshie Higashino, Tomoko Tabuki, Takashi Nakagawa
OBJECTIVE: Voice-aligned compression (VAC) is a method used in Oticon's hearing aids to provide more comfortable hearing without sacrificing speech discrimination. The complex, non-linear compression curve for the VAC strategy is designed based on the frequency profile of certain spoken Western languages. We hypothesized that hearing aids could be further customized for Japanese-speaking users by modifying the compression curve using the frequency profile of spoken Japanese. METHODS: A double-blind randomized controlled crossover study was performed to determine whether or not Oticon's modified amplification strategy (VAC-J) provides subjectively preferable hearing aids for Japanese-speaking hearing aid users compared to the same company's original amplification strategy (VAC)...
November 17, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29157507/public-attitudes-towards-involuntary-admission-and-treatment-by-mental-health-services-in-norway
#12
Inge Joa, Kjetil Hustoft, Liss Gøril Anda, Kolbjørn Brønnick, Olav Nielssen, Jan Olav Johannessen, Johannes H Langeveld
PURPOSE: The role of compulsory treatment of serious mental disorders has been the topic of ongoing public debate involving among others mental health professionals, service providers, service user advocates, relatives of service users, media commentators and politicians. However, relatively little is known about general public attitudes towards involuntary admission and compulsory treatment of people with various mental disorders. This article examines the attitudes in a representative sample of Norway's population towards the use of involuntary admission and treatment, and under which circumstances does the general public consider compulsory treatment to be justified in the Norwegian mental health care services...
November 2017: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/29155963/generating-modelling-data-from-repeat-dose-toxicity-reports
#13
Oriol López-Massaguer, Kevin Pinto-Gil, Ferran Sanz, Alexander Amberg, Lennart T Anger, Manuela Stolte, Carlo Ravagli, Philippe Marc, Manuel Pastor
Over the past decades, pharmaceutical companies have conducted a large number of high quality in vivo repeat-dose toxicity (RDT) studies for regulatory purposes. As part of the eTOX project, a high number of these studies have been compiled and integrated into a database. This valuable resource can be queried directly, but it can be further exploited to build predictive models. As the studies were originally conducted to investigate the properties of individual compounds, the experimental conditions across the studies are highly heterogeneous...
November 16, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29154306/primary-problems-associated-with-the-health-and-welfare-of-employees-observed-when-implementing-lean-manufacturing-projects
#14
Izabela Simon Rampasso, Rosley Anholon, Osvaldo Luiz Gonçalves Quelhas, Walter Leal Filho
BACKGROUND: Lean philosophy is used by companies to increase productivity and reduce costs. Although uncontested benefits are created, it is necessary to highlight the problems related to employees' health and welfare caused by implementing lean manufacturing projects. OBJECTIVE: The primary objective of this paper is to review the literature and identify the most relevant problems created by lean philosophy for employees. METHODS: Research about the theme was performed on many international databases over three months, and an initial sample of 77 papers was found...
2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29154150/exposure-to-tobacco-websites-associations-with-cigarette-and-e-cigarette-use-and-susceptibility-among-adolescents
#15
Jennifer B Unger, Lauren Bartsch
INTRODUCTION: Exposure to tobacco advertising is a risk factor for tobacco use and susceptibility among adolescents. Although tobacco company websites are ostensibly targeted to adults, some youth access these websites and are exposed to tobacco-related content. METHODS: This study analyzed data from the Population Assessment of Tobacco and Health (PATH) survey to estimate the prevalence of exposure to tobacco websites and the associations between website exposure and tobacco product use and susceptibility among adolescents in the United States...
November 10, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29153557/cardiovascular-risk-and-obesity-in-sleep-apnea-syndrome-assessed-with-the-stop-bang-questionnaire
#16
María Teófila Vicente-Herrero, Luisa Capdevila García, María Del Carmen Bellido Cambrón, María Victoria Ramírez Iñiguez de la Torre, Silvia Lladosa Marco
INTRODUCTION: Sleep disorders include a number of different processes, of which the most prevalent is the sleep apnea-hypopnea syndrome (SAHS). Prevalence of SAHS has increased worldwide, and has a significant social and health impact because of the increased cardiometabolic risk attributed to obesity and the associated metabolic syndrome. MATERIAL AND METHODS: A cross-sectional epidemiological study of 1110 workers from public service companies in the Spanish Mediterranean area (Balearic Islands and Valencian Community) was conducted between January and December 2015...
November 15, 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/29153257/pseudomonas-silesiensis-sp-nov-strain-a3-t-isolated-from-a-biological-pesticide-sewage-treatment-plant-and-analysis-of-the-complete-genome-sequence
#17
Michał A Kaminski, Ewa M Furmanczyk, Adam Sobczak, Andrzej Dziembowski, Leszek Lipinski
Microorganisms classified in to the Pseudomonas genus are a ubiquitous bacteria inhabiting variety of environmental niches and have been isolated from soil, sediment, water and different parts of higher organisms (plants and animals). Members of this genus are known for their metabolic versatility and are able to utilize different chemical compounds as a source of carbon, nitrogen or phosphorus, which makes them an interesting microorganism for bioremediation or bio-transformation. Moreover, Pseudomonas sp...
November 3, 2017: Systematic and Applied Microbiology
https://www.readbyqxmd.com/read/29153080/impact-of-social-media-for-the-hematologist-oncologist
#18
REVIEW
Nour Abuhadra, Navneet S Majhail, Aziz Nazha
In the era of modern communication, the physician and patient relationship has evolved to include an entirely new dimension-social media. This new dimension offers several opportunities for patient education, research and its dissemination, and professional development for health care providers; it can also serve as a platform for addressing important public health issues. However, these advantages come with challenges such as threats to patient and professional privacy. In this article, we dissect the benefits and drawbacks of this social evolution on the practicing hematologist-oncologist...
October 2017: Seminars in Hematology
https://www.readbyqxmd.com/read/29153077/twitter-101-and-beyond-introduction-to-social-media-platforms-available-to-practicing-hematologist-oncologists
#19
REVIEW
Michael A Thompson, Jenny Ahlstrom, Don S Dizon, Yash Gad, Greg Matthews, Howard J Luks, Andrew Schorr
Social media utilizes specific media platforms to allow increased interactivity between participants. These platforms serve diverse groups and purposes including participation from patients, family caregivers, research scientists, physicians, and pharmaceutical companies. Utilization of these information outlets has increased with integration at conferences and between conferences with the use of hashtags and "chats". In the realm of the "e-Patient" it is key to not underestimate your audience. Highly technical information is just as useful as a basic post...
October 2017: Seminars in Hematology
https://www.readbyqxmd.com/read/29152261/copd-management-as-a-model-for-all-chronic-respiratory-conditions-report-of-the-4-th-consensus-conference-in-respiratory-medicine
#20
Stefano Nardini, Fernando De Benedetto, Claudio M Sanguinetti, Salvatore Bellofiore, Stefano Carlone, Salvatore Privitera, Luciano Sagliocca, Emmanuele Tupputi, Claudio Baccarani, Gennaro Caiffa, Maria Consiglia Calabrese, Antonio Capuozzo, Salvatore Cauchi, Valentina Conio, Giuseppe Coratella, Franco Crismancich, Roberto W Dal Negro, Franco Dellarole, Maurizio Delucchi, Carlo Favaretti, Silvia Forte, Franca Matilde Gallo, Riccardo Giuliano, Marco Grandi, Antonino Grillo, Maria Rosaria Gualano, Enrico Guffanti, Salvatore Locicero, Francesco Paolo Lombardo, Marco Mantero, Roberto Marasso, Laura Martino, Michele Mastroberardino, Carlo Mereu, Roberto Messina, Margherita Neri, Bruno Franco Novelletto, Paolo Parente, Sergio Pasquinucci, Massimo Pistolesi, Mario Polverino, Agnese Posca, Luca Richeldi, Fernando Roccia, Ettore Saffi Giustini, Michelangelo Salemi, Salvatore Santacroce, Mario Schisano, Matteo Schisano, Eleonora Selvi, Andrea Silenzi, Patrizio Soverina, Claudio Taranto, Marta Ugolini, Piero Visaggi, Alessandro Zanasi
Background: Non-communicable diseases (NCDs) kill 40 million people each year. The management of chronic respiratory NCDs such as chronic obstructive pulmonary disease (COPD) is particularly critical in Italy, where they are widespread and represent a heavy burden on healthcare resources. It is thus important to redefine the role and responsibility of respiratory specialists and their scientific societies, together with that of the whole healthcare system, in order to create a sustainable management of COPD, which could become a model for other chronic respiratory conditions...
2017: Multidisciplinary Respiratory Medicine
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