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https://www.readbyqxmd.com/read/28719762/a-million-steps-developing-a-health-promotion-program-at-the-workplace-to-enhance-physical-activity
#1
María Eugenia González-Dominguez, José Manuel Romero-Sánchez, Antonio Ares-Camerino, Jose Carlos Marchena-Aparicio, Manuel Flores-Muñoz, Inés Infantes-Guzmán, José Manuel León-Asuero, Fernando Casals-Martín
The workplace is a key setting for the prevention of occupational risks and for promoting healthy activities such as physical activity. Developing a physically active lifestyle results in many health benefits, improving both well-being and quality of life. This article details the experience of two Spanish companies that implemented a program to promote physical exercise in the workplace, called "A Million Steps." This program aimed to increase the physical activity of participants, challenging them to reach at least a million steps in a month through group walks...
July 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28719222/how-drug-life-cycle-management-patent-strategies-may-impact-formulary-management
#2
Jan Berger, Jeffrey D Dunn, Margaret M Johnson, Kurt R Karst, W Chad Shear
Drug manufacturers may employ various life-cycle management patent strategies, which may impact managed care decision making regarding formulary planning and management strategies when single-source, branded oral pharmaceutical products move to generic status. Passage of the Hatch-Waxman Act enabled more rapid access to generic medications through the abbreviated new drug application process. Patent expirations of small-molecule medications and approvals of generic versions have led to substantial cost savings for health plans, government programs, insurers, pharmacy benefits managers, and their customers...
October 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/28718907/usb-storage-device-forensics-for-windows-10
#3
Ayesha Arshad, Waseem Iqbal, Haider Abbas
Significantly increased use of USB devices due to their user-friendliness and large storage capacities poses various threats for many users/companies in terms of data theft that becomes easier due to their efficient mobility. Investigations for such data theft activities would require gathering critical digital information capable of recovering digital forensics artifacts like date, time, and device information. This research gathers three sets of registry and logs data: first, before insertion; second, during insertion; and the third, after removal of a USB device...
July 18, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28718706/public-policy-and-the-next-generation-of-farmers-ranchers-producers-and-agribusiness-leaders
#4
Frank A Gasperini
The emerging, next generation of people engaged as managers in agriculture differs from the "baby boomer" farm generation that relishes certain traditions and an agrarian lifestyle. These futuristic producers and managers have been raised in a society that promulgates safety environment rules. They have witnessed lives saved by automobile seatbelts and lives improved from clean air and water. They know the basic cost of effective safety compliance is relatively fixed, regardless of the number of employees, and they are willing to invest resources that ensure a culture of safety, because it is economically beneficial, socially responsible, and probably required by the companies to whom they need to market their products...
July 18, 2017: Journal of Agromedicine
https://www.readbyqxmd.com/read/28718523/error-rate-of-automated-calculation-for-wound-surface-area-using-a-digital-photography
#5
S Yang, J Park, H Lee, J B Lee, B U Lee, B H Oh
BACKGROUND: Although measuring would size using digital photography is a quick and simple method to evaluate the skin wound, the possible compatibility of it has not been fully validated. PURPOSE: To investigate the error rate of our newly developed wound surface area calculation using digital photography. METHODS: Using a smartphone and a digital single lens reflex (DSLR) camera, four photographs of various sized wounds (diameter: 0.5-3.5 cm) were taken from the facial skin model in company with color patches...
July 17, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28718326/cns-anticancer-drug-discovery-and-development-2016-conference-insights
#6
Victor A Levin, Lauren E Abrey, Timothy P Heffron, Peter J Tonge, Arvin C Dar, William A Weiss, James M Gallo
CNS Anticancer Drug Discovery and Development November 2016, AZ, USA The 2016 second CNS Anticancer Drug Discovery and Development Conference addressed diverse viewpoints about why new drug discovery/development focused on CNS cancers has been sorely lacking. Despite more than 70,000 individuals in the USA being diagnosed with a primary brain malignancy and 151,669-286,486 suffering from metastatic CNS cancer, in 1999, temozolomide was the last drug approved by the US FDA as an anticancer agent for high-grade gliomas...
July 18, 2017: CNS Oncology
https://www.readbyqxmd.com/read/28718062/update-on-biosimilars-in-asia
#7
REVIEW
Wen-Chan Tsai
PURPOSE OF REVIEW: This review provides an update on the evolution of, manufacturing of, and regulations for biosimilars in Asian countries. RECENT FINDINGS: The use of biologics revolutionized the treatment of various diseases. However, the high cost of biologics remained unaffordable for most Asian patients and increases the financial burden of Asian governments. The development of biosimilars provides the best solution for this predicament. A great boom of biosimilars is developing in Asia...
August 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28717418/a-novel-community-driven-software-for-functional-enrichment-analysis-of-extracellular-vesicles-data
#8
Mohashin Pathan, Shivakumar Keerthikumar, David Chisanga, Riccardo Alessandro, Ching-Seng Ang, Philip Askenase, Arsen O Batagov, Alberto Benito-Martin, Giovanni Camussi, Aled Clayton, Federica Collino, Dolores Di Vizio, Juan Manuel Falcon-Perez, Pedro Fonseca, Pamali Fonseka, Simona Fontana, Yong Song Gho, An Hendrix, Esther Nolte-'t Hoen, Nunzio Iraci, Kenneth Kastaniegaard, Thomas Kislinger, Joanna Kowal, Igor V Kurochkin, Tommaso Leonardi, Yaxuan Liang, Alicia Llorente, Taral R Lunavat, Sayantan Maji, Francesca Monteleone, Anders Øverbye, Theocharis Panaretakis, Tushar Patel, Héctor Peinado, Stefano Pluchino, Simona Principe, Goran Ronquist, Felix Royo, Susmita Sahoo, Cristiana Spinelli, Allan Stensballe, Clotilde Théry, Martijn J C van Herwijnen, Marca Wauben, Joanne L Welton, Kening Zhao, Suresh Mathivanan
Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes...
2017: Journal of Extracellular Vesicles
https://www.readbyqxmd.com/read/28717397/how-do-we-avoid-disaster-when-exiting-the-european-medicines-agency-making-the-most-of-brexit-in-pharmaceutical-regulation
#9
EDITORIAL
Anthony James Hatswell
As the UK prepares to leave the EU, it must decide what path it is to take with a large number of regulatory and technical agencies who provide collaboration at the European level. In the case of pharmaceuticals, the European Medicines Agency (EMA) provides pan-European licencing for novel pharmaceuticals. Should the UK depart from the EMA system, this article highlights the loss to patients immediately (slower access to novel treatments), and in the long term by having no access to some novel products as companies choose not to launch in the UK...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28716203/testing-of-milk-replacers-for-mycobacterium-avium-subsp-paratuberculosis-by-pcr-and-bacterial-culture-as-a-possible-source-for-johne-s-disease-paratuberculosis-in-calves
#10
Johannes Lorenz Khol, Anna Lena Braun, Iva Slana, Petr Kralik, Thomas Wittek
Johne's disease (paratuberculosis) is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and can lead to severe economic losses in the affected cattle herds. The transmission of the disease occurs mainly orally, by the ingestion of MAP, which is shed in the feces and milk of infected animals. Calves show a high susceptibility for the infection compared to adult animals. The use of milk replacers can, therefore, contribute to the prevention of the transmission of the disease to calves in MAP-positive herds by preventing the ingestion of the bacterium with milk from infected animals...
September 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28715624/-chickenpox-seroprevalence-among-healthcare-and-social-assistance-workers-in-catalonia-spain
#11
Joan Inglés Torruella, Rosa Gil Soto
AIMS: Chickenpox is a frequent and contagious disease in healthcare and social assistance settings, and there are limited data on seroprevalence among workers in this sector. We estimated susceptibility to chickenpox among workers, by demographic and occupational variables, and measured the rate of seroprotection after vaccination. METHODS: A retrospective seroprevalence study of chickenpox (varicella) and serological vaccine response. The earliest recorded varicella serology, analyzed by the ELISA method, was identified for each worker from a health surveillance database of a group of medical and healthcare companies in Catalonia, recorded between 2004 and 2013...
July 2017: Archivos de Prevención de Riesgos Laborales
https://www.readbyqxmd.com/read/28715314/optimizing-electric-field-delivery-for-tdcs-virtual-humans-help-to-design-efficient-noninvasive-brain-and-spinal-cord-electrical-stimulation
#12
Pedro C Miranda, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes
Noninvasive electrical stimulation of the central nervous system is attracting increasing interest from the clinical and academic communities as well as from high-tech companies. This interest was sparked by two landmark studies conducted in 2000 and 2001 at the University of G?ttingen, Germany. Michael Nitsche and Walter Paulus showed that by passing a weak, almost imperceptible electric current between two electrodes on the scalp, they could alter the way the human brain responds to stimuli and that the effect persisted for some time after the current was stopped...
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28715080/asymmetric-alkynylation-of-%C3%AE-ketoesters-and-naphthols-promoted-by-new-chiral-biphenylic-iodanes
#13
Simon Companys, Philippe Peixoto, Cyril Bosset, Stefan Chassaing, Karinne Miqueu, Jean-Marc Sotiropoulos, Laurent Pouységu, Stephane Quideau
The preparation of new chiral biphenylic λ3-iodane reagents bearing transferable alkynyl ligands is described. These reagents transfer their carbon-based ligands onto β-ketoesters with an enantiomeric excess (ee) up to 68%, and most remarkably, enable the dearomative alkynylation of naphthols in good to high yields up to 84% ee.
July 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28714836/the-importance-of-the-evaluation-of-expectations-and-perceptions-to-improve-the-dental-service-quality
#14
Juliana Rocha, Andres Pinto, Marilia Batista, Janice Simpson de Paula, Glaucia Ambrosano
Purpose The purpose of this paper is to evaluate the use of SERVQUAL to assess service quality in Dentistry, by evaluating patients' expectations and perceptions of dental care and their association to patients' sociodemographic data. Design/methodology/approach The sample constituted of 379 subjects in the first assessment and 155 in the second phase. All employees of the companies that were clients of the dental insurance participated, a total of four companies in two states (São Paulo and Minas Gerais) of Brazil...
July 10, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28714819/an-institutional-repository-experience-at-a-large-health-care-system
#15
Brenda Fay, Jennifer Deal, Vicki Budzisz
Institutional repositories (IRs) collect, preserve, and disseminate the scholarly output of an organization. Though common in academic settings, they are less so in hospitals or health care systems. The librarians for Aurora Health Care decided to create a primarily citation-level IR to organize and promote the scholarly output of Aurora faculty, residents, and fellows using the proprietary software Digital Commons, a product of the company bepress. The repository also hosts a newly published peer-reviewed journal and includes digitized historical images and institutional memorabilia...
July 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/28714329/synthetic-sutures-clinical-evaluation-and-future-developments
#16
Roxanna E Abhari, Joana A Martins, Hayley L Morris, Pierre-Alexis Mouthuy, Andrew Carr
Today's sutures are the result of a 4000-year innovation process with regard to their materials and manufacturing techniques, yet little has been done to enhance the therapeutic value of the suture itself. In this review, we explore the historical development, regulatory database and clinical literature of sutures to gain a fuller picture of suture advances to date. First, we examine historical shifts in suture manufacturing companies and review suture regulatory databases to understand the forces driving suture development...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28713579/ring-trial-2016-for-bluetongue-virus-detection-by-real-time-rt-pcr-in-france
#17
Corinne Sailleau, Cyril Viarouge, Emmanuel Breard, Damien Vitour, Stephan Zientara
Since the unexpected emergence of BTV-8 in Northern Europe and the incursion of BTV-8 and 1 in France in 2006-2007, molecular diagnosis has considerably evolved. Several real-time RT-PCR (rtRT-PCR) methods have been developed and published, and are currently being used in many countries across Europe for BTV detection and typing. In France, the national reference laboratory (NRL) for orbiviruses develops and validates 'ready-to-use' kits with private companies for viral RNA detection. The regional laboratories network that was set up to deal with a heavy demand for analyses has used these available kits...
May 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/28713300/new-technologies-smart-or-harm-work-family-boundaries-management-gender-differences-in-conflict-and-enrichment-using-the-jd-r-theory
#18
Chiara Ghislieri, Federica Emanuel, Monica Molino, Claudio G Cortese, Lara Colombo
Background: The relationship between technology-assisted supplemental work and well-being outcomes is a recent issue in scientific literature. Whether the use of technology for work purpose in off-work time may have a positive or negative impact on work-family balance remains an open question and the role of gender in this relationship is poorly understood. Aim: According to the JD-R theory, this study aimed to investigate the relationship between off-work hours technology assisted job demand (off-TAJD) and both work-family conflict (WFC) and work-family enrichment (WFE)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28713147/to-enroll-or-not-to-enroll-a-researcher-struggles-with-the-decision-to-involve-study-participants-in-a-clinical-trial-that-could-save-their-lives
#19
Roberto Abadie
Hundreds of thousands of clinical trials are conducted annually around the world, working to further scientific knowledge and expand medical treatment. At the same time, clinical trials also present novel challenges to researchers who have access to large pools of research participants and are routinely approached by pharmaceutical companies seeking to recruit subjects for clinical trials. This case study discusses the ethical dilemmas faced by a community health investigator who received an invitation to enroll people who inject drugs (PWID) into a clinical trial of a drug that promised a new treatment option for Hepatitis C...
2017: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/28711894/-markers-of-dental-children-s-health-in-the-application-of-therapeutic-orthodontic-equipment
#20
Аліса В Пачевська, Аліна В Білошицька
INTRODUCTION: Treatment of teeth anomalies using removable and non-removable orthodontic devices in children leads to complications such as caries, gingivitis, periodontitis, oral mucosa hyperplasia. Etiopathogenetical of these diseases can be associated with biochemical changes in the composition of saliva. AIM: To determine the activity of lysozyme and amylase in oral fluid in children when using a fixed and removable orthodontic devices. MATERIALS AND METHODS: Amylase and lysozyme were studied in oral fluid...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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