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Pelvic dysfunction

Stephen F Murphy, Jonathan F Anker, Daniel J Mazur, Christel Hall, Anthony J Schaeffer, Praveen Thumbikat
INTRODUCTION: Chronic pelvic pain syndrome (CPPS) is a complex disorder that affects a large proportion of all men. A limited understanding of its etiology and pathogenesis is reflected by the absence of effective therapies. Although CPPS is deemed clinically non-infectious with no well-defined etiological role for microbes, bacteria is readily isolated from both healthy and patient prostate secretion and urine samples. Our laboratory has previously demonstrated that a specific gram-negative bacterial isolate can induce CPPS-like symptoms in mice...
September 21, 2018: Prostate
Jiang-Lei Zhang, Yu Hui, Feng Zhou, Jian-Quan Hou
PURPOSE: To explore the neuroprotective effects and its possible mechanisms of melatonin (MT) on erectile dysfunction in streptozotocin-induced diabetic rats. METHODS: Twenty-eight Sprague-Dawley rats received intraperitoneal injection of streptozotocin and 8 weeks later, the determined diabetic rats randomly got intraperitoneal injection of phosphate buffer solution (PBS) or MT. Another 12 normal rats received PBS treatment. Four weeks later, intracavernous pressure, mean arterial pressure, pathological changes in penis, and major pelvic ganglion (MPG) were measured...
September 21, 2018: International Urology and Nephrology
Sheng-Der Hsu, Cheng-Jueng Chen, I-Duo Wang, Kuen-Tze Lin, Chia-Chi Wang, Wu-Chien Chien, Chi-Hsiang Chung, Wei-Kuo Chang
BACKGROUND: Pelvic fracture with hypovolemic shock is a known crucial injury in trauma patients. Pelvic fracture with vessel injury often leads to hemodynamic complications; in a trauma scenario, evidence of other systems being affected is often absent. Bleeding cessation and resuscitation are important for these types of trauma patients. For this purpose, pelvic angiographic embolization is frequently used. Multiple studies have reported that angiographic embolization may cause erectile dysfunction (ED) in hemodynamically stable patients with pelvic fracture...
September 21, 2018: World Journal of Surgery
Francisco Castelán, Kenia López-García, Suelem Moreno-Pérez, René Zempoalteca, Dora L Corona-Quintanilla, Mario I Romero-Ortega, Ismael Jiménez-Estrada, Margarita Martínez-Gómez
INTRODUCTION: Women often develop pelvic floor dysfunction due to damage to the pelvic musculature during childbirth; however, the effect on pelvic floor nerves function is less understood. This study used adult rabbits to evaluate the electrophysiological and histological characteristics of the bulbospongiosus (Bsn) and pubococcygeus nerves (Pcn) in multiparity. METHODS: Compound nerve action potentials (CNAP) were compared between age-matched nulliparous and multiparous animals and associated to the histological characteristics of myelinated axons from the Bsn and Pcn nerves...
September 21, 2018: Brain and Behavior
Rebecca Deans, Thierry Vancaillie, William Ledger, Jinzhu Liu, Jason A Abbott
STUDY QUESTION: What are the live birth rate and risks of obstetric complications following the surgical management of intrauterine adhesions (IUA) such as Asherman syndrome (AS)? SUMMARY ANSWER: The live birth rate is 63.7%, and obstetric complications including placentation issues, prematurity and postpartum hysterectomy require that pregnancies in women after treatment for IUA should be considered moderate to high risk. WHAT IS KNOWN ALREADY: Studies reviewing short-term surgical, menstrual and fertility outcomes following hysteroscopic management are reassuring, with success correlated to the severity of IUA...
September 18, 2018: Human Reproduction
Hong Pan, Yong Bao, Honghao Cao, Rongjiang Jin, Pu Wang, Junmei Zhang
AIMS: To evaluate the value of magnetic stimulation (MS) in patients with pelvic floor dysfunction (PFD). METHODS: The Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement was followed. We searched five databases for articles published until November 2017. Included studies investigated the effects of MS on PFD. Meta-analysis of RCTs was performed using a random effects model, and narrative analysis was undertaken where meta-analysis was not possible...
September 17, 2018: Neurourology and Urodynamics
Tiago Antunes-Lopes, Alice Vasconcelos, Daniel Costa, Ana Charrua, João Neves, João Silva, Francisco Cruz, Carlos Silva
OBJECTIVE: To investigate LUTS and urinary levels of neuro-inflammatory, inflammatory and oxidative stress markers in elderly men with chronic pelvic ischemia (CPI) caused by significant aorto-iliac disease. METHODS: Thirteen men aged over 60 years, with aorta, unilateral or bilateral common/internal iliac artery occlusion documented by computed tomography angiography or angiography, were enrolled from the vascular surgery department. Twelve sex and age-matched controls, without significant aorto-iliac disease were used for comparison...
September 13, 2018: Urology
Deenika R Benjamin, Helena J Frawley, Nora Shields, Alexander T M van de Water, Nicholas F Taylor
BACKGROUND: Diastasis of the rectus abdominis muscle (DRAM) is common during and after pregnancy. OBJECTIVES: To determine the association between: the presence of DRAM and low back pain, lumbo-pelvic pain, incontinence, pelvic organ prolapse, abdominal muscle performance or health-related quality of life; and between DRAM width and severity of these outcomes. DATA SOURCES: Six electronic databases (EMBASE, Medline, CINAHL, PUBMED, AMED and PEDro)...
July 24, 2018: Physiotherapy
Ashley N Dixon, Jack C Webb, Jessica L Wenzel, J Stuart Wolf, E Charles Osterberg
The acute management of pelvic fracture urethral injuries (PFUIs) remains a controversial topic. Currently, suprapubic tube (SPT) placement with delayed repair or primary realignment (PR) represents the strategies used to treat patients. While many will advocate the use of one technique over the other, the 2014 American Urological Association (AUA) Guidelines give providers the option for the management PFUI. Current literature evaluates these two interventions, focusing on the incidence of re-stricture formation, erectile dysfunction, and urinary incontinence...
August 2018: Translational Andrology and Urology
Rachel A Moses, John Patrick Selph, Bryan B Voelzke, Joshua Piotrowski, Jairam R Eswara, Bradley A Erickson, Shubham Gupta, Roger R Dmochowski, Niels V Johnsen, Anand Shridharani, Sarah D Blaschko, Sean P Elliott, Ian Schwartz, Catherine R Harris, Kristy Borawski, Bradley D Figler, E Charles Osterberg, Frank N Burks, William Bihrle, Brandi Miller, Richard A Santucci, Benjamin N Breyer, Brian Flynn, Ty Higuchi, Fernando J Kim, Joshua A Broghammer, Angela P Presson, Jeremy B Myers
Background: Pelvic fracture urethral injuries (PFUI) occur in up to 10% of pelvic fractures. It remains controversial whether initial primary urethral realignment (PR) after PFUI decreases the incidence of urethral obstruction and the need for subsequent urethral procedures. We present methodology for a prospective cohort study analyzing the outcomes of PR versus suprapubic cystostomy tube (SPT) after PFUI. Methods: A prospective cohort trial was designed to compare outcomes between PR (group 1) and SPT placement (group 2)...
August 2018: Translational Andrology and Urology
Shuai-Xi Yang, Zhen-Qiang Sun, Quan-Bo Zhou, Ji-Zhong Xu, Yuan Chang, Kun-Kun Xia, Gui-Xian Wang, Zhen Li, Jun-Min Song, Zhi-Yong Zhang, Wei-Tang Yuan, Jin-Bo Liu
PURPOSE: This retrospective study was designed to assess the safety and effectiveness of open, laparoscopic, robotic colorectal cancer surgery. METHODS: Three hundred patients with colorectal cancer who underwent curative resection in the First Affiliated Hospital of Zhengzhou University between February 2014 and May 2016 were included. Patients were classified into open surgery group, laparoscopic surgery group, and robot-assisted group. RESULTS: The blood loss in laparoscopic surgery group was less than that in open surgery group, and the blood loss in robot-assisted group less was than the open surgery group...
January 1, 2018: Technology in Cancer Research & Treatment
Marco M E Vogel, Kerstin A Kessel, Jürgen E Gschwend, Wilko Weichert, Jan J Wilkens, Stephanie E Combs
PURPOSE: The present study aims to evaluate both early and late toxicity profiles of patients receiving immediate postoperative radiotherapy (RT; adjuvant RT or additive RT) compared to salvage RT. METHODS: We evaluated 253 patients with prostate cancer treated with either immediate postoperative (adjuvant RT, n = 42; additive RT, n = 39) or salvage RT (n = 137). Thirty-five patients received salvage treatment but did not achieve a postoperative prostate specific antigen (PSA) level <0...
September 4, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Keyla M Dos Santos, Thuane H da Roza, Soraia C Tonon da Luz, Julia P Hort, Joyce M Kruger, Bruna Schevchenco
BACKGROUND: urinary incontinence (UI) is a pelvic floor dysfunction that can affect nulliparous female athletes due to the effect of sports modalities on the pelvic floor muscles (PFM). OBJECTIVES: To verify and quantify the loss of urine in nulliparous athletes during 1-hour of sports training using a modified pad test protocol. DESIGN: cross-sectional. SETTING: secondary, institutional practice. PARTICIPANTS: 104 nulliparous athletes...
September 1, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
Wan-Mei Chen, Qi-Yun Yang, Jun Bian, Da-Yu Han, De-Hui Lai, Xiang-Zhou Sun, Chun-Hua Deng
Objective: To investigate the protective effect of human urine-derived stem cells (USCs) on erectile function and cavernous structure in rats with cavernous nerve injury (CNI). METHODS: Sixty adult male SD rats with normal sexual function were randomly divided into four groups of equal number: sham operation, bilateral CNI (BCNI) model control, phosphate buffered saline (PBS), and USC. The BCNI model was established in the latter three groups of rats by clamping the bilateral cavernous nerves...
June 2018: Zhonghua Nan Ke Xue, National Journal of Andrology
Seif Eid, Joe Iwanaga, Jens R Chapman, Rod J Oskouian, Marios Loukas, R Shane Tubbs
The superior hypogastric plexus (SHP) is a complex nervous collection located at the lumbosacral region below the level of the aortic bifurcation. As a part of the autonomic nervous system, it is an extension of the preaortic plexuses and continues bilaterally as the hypogastric nerves that ultimately contribute to the inferior hypogastric plexus. Although commonly described as a plexiform structure, several morphological variations exist. Damage to the SHP can occur during anterior and anterolateral approaches to the lumbosacral spine leading to dysfunction of the abdominopelvic viscera...
August 30, 2018: World Neurosurgery
M C P Vila Pouca, J P S Ferreira, D A Oliveira, M P L Parente, Teresa Mascarenhas, R M Natal Jorge
Injuries sustained by the pelvic floor muscles during childbirth are one of the major risk factors for the development of pelvic floor dysfunctions. The ability to predict the loss of the tissue integrity and the most affected regions prior to the childbirth would represent a compelling difference in choosing the appropriate management of labour. Previous biomechanical studies, using the finite element method, were able to simulate a vaginal delivery and analyse the mechanical effects on the pelvic floor muscles during the passage of the foetus...
August 11, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Toscane C Noordhoff, Jeroen R Scheepe, Lisette A 't Hoen, Tebbe A R Sluis, Bertil F M Blok
AIMS: The Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ-15) evaluates symptoms of sexual dysfunction in patients with multiple sclerosis (MS). The objective of this study was to provide and validate a Dutch version of the MSISQ-15 in patients with neurological disease such as MS and spinal cord injury (SCI). METHODS: The linguistic validation process of the original English MSISQ-15 into Dutch was performed according to standardized guidelines. Sexually active patients with MS or spinal cord disorders, including SCI and cauda equine syndrome, who visited a tertiary urology center or a rehabilitation center completed the MSISQ-15, Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) in women, or International Index of Erection Function (IIEF-15) in men at baseline (test) and 2 weeks later (retest)...
August 31, 2018: Neurourology and Urodynamics
Ye Zhang, Xiaochen Song, Meng Mao, Jia Kang, Fangfang Ai, Lan Zhu
OBJECTIVE: To evaluate the long-term safety and efficacy of tension-free vaginal tape (TVT). DESIGN: Prospective observational study (Canadian Task Force Classification II-2). SETTING: Tertiary referral center in China. PATIENTS: Between January 2004 and December 2005, 85 consecutive patients who underwent TVT procedure were included. Patients with mixed incontinence or pelvic organ prolapse requiring surgery were excluded...
August 27, 2018: Journal of Minimally Invasive Gynecology
Robert A Laird, Jennifer L Keating, Peter Kent
BACKGROUND: Movement dysfunctions have been associated with persistent low back pain (LBP) but optimal treatment remains unclear. One possibility is that subgroups of persistent LBP patients have differing movement characteristics and therefore different responses to interventions. This study examined if there were patterns of flexion-related lumbo-pelvic kinematic and EMG parameters that might define subgroups of movement. METHODS: This was a cross-sectional, observational study of 126 people without any history of significant LBP and 140 people with persistent LBP (n = 266)...
August 28, 2018: BMC Musculoskeletal Disorders
Angélica Mércia Pascon Barbosa, Nivaldo Antonio Parizotto, Cristiane Rodrigues Pedroni, Mariana Arias Avila, Richard Eloin Liebano, Patricia Driusso
Electrical stimulation is widely used for pelvic floor muscle dysfunctions (PFMDs), but studies are not always clear about the parameters used, jeopardizing their reproduction. As such, this study aimed to be a reference for researchers and clinicians when using electrical stimulation for PFMD. This report was designed by experts on electrophysical agents and PFMD who determined all basic parameters that should be described. The terms were selected from the Medical Subject Headings database of controlled vocabulary...
August 24, 2018: International Urogynecology Journal
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