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https://www.readbyqxmd.com/read/29351259/dietary-fatty-acids-alter-lipid-profiles-and-induce-myocardial-dysfunction-without-causing-metabolic-disorders-in-mice
#1
Bainian Chen, Yifan Huang, Dong Zheng, Rui Ni, Mark A Bernards
Oversupply of bulk saturated fatty acids (SFA) induces metabolic disorders and myocardial dysfunction. We investigated whether, without causing metabolic disorders, the uptake of individual dietary SFA species alters lipid profiles and induces myocardial dysfunction. C57BL/6 mice were fed various customized long-chain SFA diets (40% caloric intake from SFA), including a beef tallow (HBD), cocoa butter (HCD), milk fat (HMD) and palm oil diet (HPD), for 6 months. An isocaloric fat diet, containing medium-chain triglycerides, served as a control (CHD)...
January 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29343956/essential-oil-loaded-lipid-nanoparticles-for-wound-healing
#2
Francesca Saporito, Giuseppina Sandri, Maria Cristina Bonferoni, Silvia Rossi, Cinzia Boselli, Antonia Icaro Cornaglia, Barbara Mannucci, Pietro Grisoli, Barbara Vigani, Franca Ferrari
Chronic wounds and severe burns are diseases responsible for severe morbidity and even death. Wound repair is a crucial process and tissue regeneration enhancement and infection prevention are key factors to minimize pain, discomfort, and scar formation. The aim of this work was the development of lipid nanoparticles (solid lipid nanoparticles and nanostructured lipid carriers [NLC]), to be loaded with eucalyptus or rosemary essential oils and to be used, as medical devices, to enhance healing of skin wounds...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29337601/mango-kernel-fat-fractions-as-potential-healthy-food-ingredients-a-review
#3
Jun Jin, Qingzhe Jin, Casimir C Akoh, Xingguo Wang
Mango kernel fat (MKF) has been reported to have high functional and nutritional potential. However, its application in food industry has not been fully explored or developed. In this review, the chemical compositions, physical properties and potential health benefits of MKF are described. MKF is a unique fat consisting of 28.9-65.0% of 1,3-distearoyl-2-oleoyl-glycerol with excellent oxidative stability index (58.8-85.2 h at 110 °C), making the fat and its fractions suitable for use as high-value added food ingredients such as cocoa butter alternatives, trans-free shortenings, and a source of natural antioxidants (e...
January 16, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29331224/centrifugal-partition-chromatography-enables-selective-enrichment-of-trimeric-and-tetrameric-proanthocyanidins-for-biomaterial-development
#4
Rasika S Phansalkar, Joo-Won Nam, Shao-Nong Chen, James B McAlpine, Ariene A Leme, Berdan Aydin, Ana-Karina Bedran-Russo, Guido F Pauli
Proanthocyanidins (PACs) find wide applications for human use including food, cosmetics, dietary supplements, and pharmaceuticals. The chemical complexity associated with PACs has triggered the development of various chromatographic techniques, with countercurrent separation (CCS) gaining in popularity. This study applied the recently developed DESIGNER (Depletion and Enrichment of Select Ingredients Generating Normalized Extract Resources) approach for the selective enrichment of trimeric and tetrameric PACs using centrifugal partition chromatography (CPC)...
December 21, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29330660/theobromine-consumption-does-not-improve-fasting-and-postprandial-vascular-function-in-overweight-and-obese-subjects
#5
Lotte Smolders, Ronald P Mensink, Jose J van den Driessche, Peter J Joris, Jogchum Plat
BACKGOUND: Theobromine, a component of cocoa, may favorably affect conventional lipid-related cardiovascular risk markers, but effects on flow-mediated dilation (FMD) and other vascular function markers are not known. OBJECTIVE: To evaluate the effects of 4-week theobromine consumption (500 mg/day) on fasting and postprandial vascular function markers. DESIGN: In a randomized, double-blind crossover study, 44 apparently healthy overweight (N = 30) and obese (N = 14) men and women with low HDL-C concentrations, consumed daily 500 mg theobromine or placebo for 4 weeks...
January 12, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29329924/effects-of-dark-chocolate-on-endothelial-function-in-patients-with-non-alcoholic-steatohepatitis
#6
L Loffredo, F Baratta, P Ludovica, S Battaglia, R Carnevale, C Nocella, M Novo, G Pannitteri, F Ceci, F Angelico, F Violi, M Del Ben
BACKGROUND AND AIM: Oxidative stress plays a pivotal role in inducing endothelial dysfunction and progression from simple fatty liver steatosis (FLD) to non-alcoholic steatohepatitis (NASH). Polyphenols could reduce oxidative stress and restore endothelial function by inhibiting the nicotinamide-adenine-dinucleotide-phosphate (NADPH) oxidase isoform Nox2. The aim of this study was to assess endothelial function and oxidative stress in a population affected by simple FLD and NASH. Furthermore, we analysed the effect of high vs low content of cocoa polyphenols on endothelial function and oxidative stress in patients with NASH...
November 13, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29322590/cocoa-agroforestry-is-less-resilient-to-sub-optimal-and-extreme-climate-than-cocoa-in-full-sun-reply-to-norgrove-2017
#7
Issaka Abdulai, Philippe Vaast, Munir P Hoffmann, Richard Asare, Laurence Jassogne, Piet Van Asten, Reimund P Rötter, Sophie Graefe
The critique of Norgrove, (2017) addresses two main points, which are discussed below (i) Resilience of cocoa agroforestry versus full sun under extreme climatic conditions In our study we covered extreme climatic events, a heat-wave combined with a severe dry season lasting longer than usual and killing cocoa trees under shade. These climatic conditions were not only observed at our study plots, but also in the larger cocoa cultivation region (Fig 1). In line with our observations, "certain cocoa cooperatives in Ivory Coast reported that shade trees in their cocoa fields accentuated the drought stress during the 2015 drought event" (1 Andrew Broosk, pers comm)...
January 11, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29313898/modulation-of-saturation-and-chain-length-of-fatty-acids-in-saccharomyces-cerevisiae-for-production-of-cocoa-butter-like-lipids
#8
David Bergenholm, Michael Gossing, Yongjun Wei, Verena Siewers, Jens Nielsen
Chain length and degree of saturation plays an important role for the characteristics of various products derived from fatty acids, such as fuels, cosmetics and food additives. The seeds of Theobroma cacao are the source of cocoa butter, a natural lipid of high interest for the food and cosmetics industry. Cocoa butter is rich in saturated fatty acids that are stored in the form of triacylglycerides (TAGs). One of the major TAG species of cocoa butter, consisting of two stearic acid molecules and one oleic acid molecule (stearic acid-oleic acid-stearic acid, sn-SOS), is particularly rare in nature as the saturated fatty acid stearic acid is typically found only in low abundance...
January 4, 2018: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29313749/the-potential-effects-of-caffeinated-beverages-on-insulin-sensitivity
#9
E Paul Cherniack, Natalie Buslach, Heather F Lee
Caffeinated beverages, most commonly tea and coffee, may have important effects on insulin regulation that may give their consumption an important role among nutritional factors in the development of diseases of glucose and insulin metabolism, such as diabetes and atherosclerotic vascular diseases. These beverages include compounds that may have contradictory effects on insulin and glucose: Caffeine impairs insulin sensitivity, but polyphenolic molecules within tea, coffee, and cocoa augment the effects of insulin...
January 9, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29310543/cadmium-and-lead-in-cocoa-powder-and-chocolate-products-in-the-u-s-market
#10
Eileen Abt, Jennifer Fong Sam, Patrick Gray, Lauren Posnick Robin
Cocoa powder and chocolate products are known to sometimes contain cadmium (Cd) and lead (Pb) from environmental origins. A convenience sample of cocoa powder, dark chocolate, milk chocolate, and cocoa nib products was purchased at retail in the U.S. and analyzed using Inductively Coupled Plasma Mass Spectrometry to assess Cd and Pb concentrations. Cd and Pb were evaluated in relation to the percent cocoa solids and to the reported origin of the cocoa powder and chocolate products. Cd ranged from 0.004-3.15 mg/kg and Pb ranged from <LOD-0...
January 8, 2018: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/29309470/the-evidence-for-herbal-and-botanical-remedies-part-2
#11
Michael Malone, Gary Tsai
In part one of this series, we discussed the studies that have been done on capsaicin, butterbur, green tea, and peppermint. In this installment, we outline the research on 5 additional remedies: turmeric/curcumin, which may be of benefit in ulcerative colitis; chamomile, which appears to offer relief to patients with anxiety; rosemary, which may help treat alopecia; as well as coffee and cocoa, which may have some cardiovascular benefits.
January 2018: Journal of Family Practice
https://www.readbyqxmd.com/read/29299877/cocoa-flavanol-supplementation-and-exercise-a-systematic-review
#12
REVIEW
Lieselot Decroix, Danusa Dias Soares, Romain Meeusen, Elsa Heyman, Cajsa Tonoli
BACKGROUND: Cocoa flavanols (CFs) have antioxidant and anti-inflammatory capacities and can improve vascular function. It has recently been suggested that CF intake may improve exercise performance and recovery. This systematic review aimed to evaluate the literature on the effects of CF intake on exercise performance and recovery and exercise-induced changes in vascular function, cognitive function, oxidative stress, inflammation, and metabolic parameters. METHODS: Two electronic databases (Pubmed and Web of Science) were searched for studies examining the combination of CF intake and exercise in humans (up to 28 March 2017)...
January 3, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29290363/flavanol-rich-cocoa-consumption-enhances-exercise-induced-executive-function-improvements-in-humans
#13
Hayato Tsukamoto, Tadashi Suga, Aya Ishibashi, Saki Takenaka, Daichi Tanaka, Yoshitaka Hirano, Takafumi Hamaoka, Kazushige Goto, Kumiko Ebi, Tadao Isaka, Takeshi Hashimoto
OBJECTIVE: Aerobic exercise is known to acutely improve cognitive functions, such as executive function (EF) and memory function (MF). Additionally, consumption of flavanol-rich cocoa has been reported to acutely improve cognitive function. The aim of this study was to determine whether high cocoa flavanol (CF; HCF) consumption would enhance exercise-induced improvement in cognitive function. To test this hypothesis, we examined the combined effects of HCF consumption and moderate-intensity exercise on EF and MF during postexercise recovery...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29287336/toxic-metal-levels-in-cocoa-powder-and-chocolate-by-icp-ms-method-after-microwave-assisted-digestion
#14
Gianluigi Maria Lo Dico, Fabio Galvano, Giacomo Dugo, Carlo D'ascenzi, Andrea Macaluso, Antonio Vella, Giuseppe Giangrosso, Gaetano Cammilleri, Vincenzo Ferrantelli
The Commission Regulation (EC) Regulation N. 488/2014, established the concentration limits for cadmium in specific products based on cocoa and chocolate products as from January 2019. Based on this information there is a need to determine ultratrace levels of elements that might be presents in cocoa and chocolate products. In this work, the concentrations of Arsenic, Antimony, Cadmium, Chromium, Lead, Selenium and Vanadium were evaluated in cocoa powder and chocolate by the validation of an ICP-MS method. Good selectivity/specificity, recovery, repeatability and within-laboratory reproducibility, LOD, LOQ, range of linearity, standard measurement uncertainty parameters for method validation were achieved, in accordance with Commission Regulation...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29280563/characterization-of-the-proteome-of-theobroma-cacao-beans-by-nanouhplc-esi-ms-ms
#15
Emanuele Scollo, David Neville, M Jose Oruna-Concha, Martine Trotin, Rainer Cramer
Cocoa seed storage proteins play an important role in flavour development as aroma precursors are formed from their degradation during fermentation. Major proteins in the beans of Theobroma cacao are the storage proteins belonging to the vicilin and albumin classes. Although both these classes of proteins have been extensively characterized, there is still limited information on the expression and abundance of other proteins present in cocoa beans. This work is the first attempt to characterize the whole cocoa bean proteome by nanoUHPLC-ESI MS/MS analysis using tryptic digests of cocoa bean protein extracts...
December 27, 2017: Proteomics
https://www.readbyqxmd.com/read/29232891/the-effect-of-polyphenol-rich-interventions-on-cardiovascular-risk-factors-in-haemodialysis-a-systematic-review-and-meta-analysis
#16
REVIEW
Wolfgang Marx, Jaimon Kelly, Skye Marshall, Stacey Nakos, Katrina Campbell, Catherine Itsiopoulos
End-stage kidney disease is a strong risk factor for cardiovascular-specific mortality. Polyphenol-rich interventions may attenuate cardiovascular disease risk factors; however, this has not been systematically evaluated in the hemodialysis population. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the following databases were searched: Cochrane Library (http://www.cochranelibrary.com/), MEDLINE (https://health.ebsco.com/products/medline-with-full-text), Embase (https://www...
December 11, 2017: Nutrients
https://www.readbyqxmd.com/read/29226130/in-vitro-activity-of-lactobacilli-with-probiotic-potential-isolated-from-cocoa-fermentation-against-gardnerella-vaginalis
#17
Wallace Felipe Blohem Pessoa, Ana Clara Correia Melgaço, Milena Evangelista de Almeida, Louise Pereira Ramos, Rachel Passos Rezende, Carla Cristina Romano
Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanisms involving probiotic and antagonistic action as well as their effect on human vaginal cells have not yet been fully elucidated. The aim of this study was to evaluate the functional and antagonistic properties of three strains of lactobacilli isolated from cocoa fermentation (Lactobacillus fermentum 5...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29222066/large-scale-randomized-clinical-trials-of-bioactives-and-nutrients-in-relation-to-human-health-and-disease-prevention-lessons-from-the-vital-and-cosmos-trials
#18
REVIEW
Susanne Rautiainen, Howard D Sesso, Joann E Manson
Several bioactive compounds and nutrients in foods have physiological properties that are beneficial for human health. While nutrients typically have clear definitions with established levels of recommended intakes, bioactive compounds often lack such a definition. Although a food-based approach is often the optimal approach to ensure adequate intake of bioactives and nutrients, these components are also often produced as dietary supplements. However, many of these supplements are not sufficiently studied and have an unclear role in chronic disease prevention...
December 5, 2017: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/29215784/neither-dark-nor-light-but-shades-in-between-cocoa-merits-a-finer-sampling
#19
Lindsey Norgrove
Abdulai et al. (2017), working in Akumadan in the forest-savannah transition zone of Ghana, compared three cocoa (Theobroma cacao) systems in periods of wet, dry and extremely dry weather. These were cocoa grown: (a) in an agroforestry system under a leguminous tree (Albizia ferruginea); (b) in an agroforestry system under one of the most common shade trees (Antiaris toxicaria) in the region; and, (c) under "full sun conditions". During the extremely dry period, the cocoa in agroforestry systems had massive stress, reduced sap flux and high mortality...
December 7, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29207204/cocoa-production-monocultures-are-not-the-solution-to-climate-adaptation-response-to-abdulai-et%C3%A2-al-2017
#20
Thomas Cherico Wanger, Dirk Hölscher, Edzo Veldkamp, Teja Tscharntke
Cocoa is a major trade commodity that is seeing increasing demand, but also climate-related yield declines1 . There has been an ongoing discussion whether both, the effective adaptation of plantations to climate change and a long term increase of cocoa yields, can only be achieved with shaded agroforestry or also with full-sun monocultures2 . Abdulai et al. 3 investigated the climate adaptation potential of full-sun cocoa monocultures and shaded agroforestry in Ghana West Africa. This article is protected by copyright...
December 5, 2017: Global Change Biology
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