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https://www.readbyqxmd.com/read/27914320/biochemical-precursor-effects-on-the-fatty-acid-production-in-cell-suspension-cultures-of-theobroma-cacao-l
#1
O Parra, A M Gallego, A Urrea, L F Rojas, C Correa, L Atehortúa
Cocoa butter (CB) is composed of 96% palmitic, stearic, oleic, linoleic and linolenic fatty acids that are responsible for the hardness, texture and fusion properties of chocolate. Through in vitro plant cell culture it is possible to modify CB lipid profiles and to study the fatty acid biosynthesis pathway on a subcellular level, evaluating fundamental aspects to enhance in vitro fatty acid production in a specific and controlled way. In this research, culture media was supplemented with acetate, biotin, pyruvate, bicarbonate and glycerol at three different concentrations and the effects on the biomass production (g/L), cell viability, and fatty acids profile and production was evaluated in in vitro cell suspensions culture...
November 25, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27904388/content-of-total-phenolics-flavan-3-ols-and-proanthocyanidins-oxidative-stability-and-antioxidant-capacity-of-chocolate-during-storage
#2
Jovanka Laličić-Petronijević, Draženka Komes, Stanislava Gorjanović, Ana Belščak-Cvitanović, Lato Pezo, Ferenc Pastor, Sanja Ostojić, Jovanka Popov-Raljić, Desanka Sužnjević
Antioxidant (AO) capacity of chocolates with 27, 44 and 75% cocoa was assessed after production and during twelve months of storage by direct current (DC) polarographic assay, based on the decrease of anodic current caused by the formation of hydroxo-perhydroxyl mercury(II) complex (HPMC) in alkaline solutions of hydrogen peroxide at potentials of mercury oxidation, and two spectrophotometric assays. Relative antioxidant capacity index (RACI) was calculated by taking the average value of the AO assay (the sample mass in all assays was identical)...
March 2016: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/27892582/lubrication-of-chocolate-during-oral-processing
#3
S A Rodrigues, N Selway, M P Morgenstern, L Motoi, J R Stokes, B J James
The structure of chocolate is drastically transformed during oral processing from a composite solid to an oil/water fluid emulsion. Using two commercial dark chocolates varying in cocoa solids content, this study develops a method to identify the factors that govern lubrication in molten chocolate and saliva's contribution to lubrication following oral processing. In addition to chocolate and its individual components, simulated boluses (molten chocolate and phosphate buffered saline), in vitro boluses (molten chocolate and whole human saliva) and ex vivo boluses (chocolate expectorated after chewing till the point of swallow) were tested...
November 28, 2016: Food & Function
https://www.readbyqxmd.com/read/27885388/recovery-of-forest-and-phylogenetic-structure-in-abandoned-cocoa-agroforestry-in-the-atlantic-forest-of-brazil
#4
Samir Gonçalves Rolim, Regina Helena Rosa Sambuichi, Götz Schroth, Marcelo Trindade Nascimento, José Manoel Lucio Gomes
Cocoa agroforests like the cabrucas of Brazil's Atlantic forest are among the agro-ecosystems with greatest potential for biodiversity conservation. Despite a global trend for their intensification, cocoa agroforests are also being abandoned for socioeconomic reasons especially on marginal sites, because they are incorporated in public or private protected areas, or are part of mandatory set-asides under Brazilian environmental legislation. However, little is known about phylogenetic structure, the processes of forest regeneration after abandonment and the conservation value of former cabruca sites...
November 25, 2016: Environmental Management
https://www.readbyqxmd.com/read/27881914/habitual-cocoa-intake-reduces-arterial-stiffness-in-postmenopausal-women-regardless-of-intake-frequency-a-randomized-parallel-group-study
#5
Takanobu Okamoto, Ryota Kobayashi, Midori Natsume, Koichi Nakazato
Arterial stiffness is substantially higher in postmenopausal than in premenopausal women. Daily cocoa intake has been shown to reduce central arterial stiffness in health adults, regardless of age; however, the effect of cocoa-intake frequency on arterial stiffness in postmenopausal women remains unclear. Therefore, the purpose of this study was to investigate the effects of cocoa-intake frequency on arterial stiffness in postmenopausal women. A total of 26 postmenopausal women (mean age ± standard deviation 64±12 years) were randomly assigned to two groups with different cocoa-intake frequencies: one group ingested 17 g of cocoa once daily except on Sundays (every-day group, n=13), and the other ingested 17 g of cocoa twice daily every other day (every-other-day group, n=13)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27881064/functional-foods-for-health-the-interrelated-antioxidant-and-anti-inflammatory-role-of-fruits-vegetables-herbs-spices-and-cocoa-in-humans
#6
Mauro Serafini, Ilaria Peluso
The health benefits of plant food-based diets could be related to both integrated antioxidant and anti-inflammatory mechanisms exerted by a wide array of phytochemicals present in fruit, vegetables, herbs and spices. Therefore, there is mounting interest in identifying foods, food extracts and phytochemicals formulations from plant sources which are able to efficiently modulate oxidative and inflammatory stress to prevent diet-related diseases. This paper reviews available evidence about the effect of supplementation with selected fruits, vegetables, herbs, spices and their extracts or galenic formulation on combined markers of redox and inflammatory status in humans...
November 22, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27864733/-epicatechin-a-natural-flavonoid-compound-protects-astrocytes-against-hemoglobin-toxicity-via-nrf2-and-ap-1-signaling-pathways
#7
Xi Lan, Xiaoning Han, Qian Li, Jian Wang
(-)-Epicatechin is a brain-permeable, natural product found at high concentrations in green tea and cocoa. Our previous research has shown that (-)-epicatechin treatment reduces hemorrhagic stroke injury via nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway in vivo. However, the mechanism of action of this compound in modulation of oxidant stress and in protection against hemoglobin-induced astrocyte injury is unclear. Therefore, we explored the cellular and molecular mechanisms that underlie these protective effects in vitro...
November 18, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27849355/acute-cocoa-flavanol-improves-cerebral-oxygenation-without-enhancing-executive-function-at-rest-or-after-exercise
#8
Lieselot Decroix, Cajsa Tonoli, Danusa D Soares, Semah Tagougui, Elsa Heyman, Romain Meeusen
Acute exercise-induced improvements in cognitive function are accompanied by increased (cerebral) blood flow and increased brain-derived neurotrophic factor (BDNF) levels. Acute cocoa flavanol (CF) intake may improve cognitive function, cerebral blood flow (in humans), and BNDF levels (in animals). This study investigated (i) the effect of CF intake in combination with exercise on cognitive function and (ii) cerebral hemodynamics and BDNF in response to CF intake and exercise. Twelve healthy men participated in this randomized, double-blind, crossover study...
December 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27830580/effect-of-prenatal-antioxidant-intake-on-infants-respiratory-infection-is-modified-by-a-cd14-polymorphism
#9
Seo Ah Hong, Eun Lee, Sung Ok Kwon, Kyung Won Kim, Youn Ho Shin, Kang Mo Ahn, Eun-Jin Kim, Jeom-Gyu Lee, Se-Young Oh, Soo-Jong Hong
BACKGROUND: Prenatal maternal diet may influence disease susceptibility in offspring with specific genetic backgrounds. We hypothesized that interactions between prenatal antioxidant intake and polymorphisms in immunity genes infl uence respiratory tract infection (RTI) susceptibility in infants at 12 months of age. METHODS: This study included 550 infants. In the Cohort for Childhood Origin of Asthma and Allergic Diseases (COCOA) birth cohort study, prenatal maternal diet was assessed by administering a food frequency questionnaire...
November 3, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/27827474/the-prothrombotic-state-associated-with-obesity-induced-hypertension-is-reduced-by-cocoa-and-its-main-flavanols
#10
G M Rabadán-Chávez, E Reyes-Maldonado, L Quevedo-Corona, N Paniagua-Castro, G Escalona-Cardoso, M E Jaramillo-Flores
BACKGROUND: Little is known about the effects of cocoa and its main flavanols on the prothrombotic state associated with the development of hypertension in diet-induced obesity models. PURPOSE: To evaluate the effects of cocoa powder, cocoa extract and their main flavanols on plasma biomarkers related to impaired coagulation and fibrinolysis and its association with hypertension and obesity-related metabolic disorders in rats fed a hypercaloric diet. METHODS: Male Wistar rats were randomly assigned to 7 treatment groups (n = 7): normal diet (ND); hypercaloric diet control group (HCD); HCD + cocoa powder (CO); HCD + cocoa extract (CO-EX); HCD + (-)-epicatechin (EPI); HCD + (+)-catechin (CAT); and HCD + procyanidin B2 (PB2)...
November 9, 2016: Food & Function
https://www.readbyqxmd.com/read/27816760/high-molecular-weight-cocoa-procyanidins-possess-enhanced-insulin-enhancing-and-insulin-mimetic-activities-in-human-primary-skeletal-muscle-cells-compared-to-smaller-procyanidins
#11
Suzanne M Bowser, William T Moore, Ryan P McMillan, Melanie R Dorenkott, Katheryn M Goodrich, Liyun Ye, Sean F O'Keefe, Matthew W Hulver, Andrew P Neilson
Dysregulation of glucose metabolism is a primary hallmark of metabolic disease (i.e., diabetes, obesity, etc.). Complementary nonpharmaceutical strategies are needed to prevent and/or ameliorate dysregulation of glucose metabolism and prevent progression from normoglycemia to prediabetes and type 2 diabetes across the lifespan. Cocoa compounds, particularly the procyanidins, have shown promise for improving insulin sensitivity and blood glucose homeostasis. However, the molecular mechanisms by which cocoa procyanidins exert these functions remain poorly understood...
January 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27804893/phenolic-enriched-foods-sources-and-processing-for-enhanced-health-benefits
#12
Gordon J McDougall
Polyphenols are ubiquitous secondary products present in many plant foods. Their intake has been associated with health benefits ranging from reduced incidence of CVD, diabetes and cancers to improved neurodegenerative outcomes. Major dietary sources include beverages such as coffee, teas and foods such as chocolate. Fruits are also major sources and berries in particular are a palatable source of a diverse range of polyphenol components. There are a number of ways that polyphenol uptake could be increased and healthier polyphenol-rich foods could be produced with specific compositions to target-specific health effects...
November 2, 2016: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/27793096/inhibition-of-staphylococcus-aureus-biofilm-by-lactobacillus-isolated-from-fine-cocoa
#13
Tauá Alves Melo, Thalis Ferreira Dos Santos, Milena Evangelista de Almeida, Luiz Alberto Gusmão Fontes Junior, Ewerton Ferraz Andrade, Rachel Passos Rezende, Lucas Miranda Marques, Carla Cristina Romano
BACKGROUND: Biofilm production represents an important virulence and pathogenesis factor for Staphylococcus aureus. The formation of biofilms on medical devices is a major concern in hospital environments, as they can become a constant source of infection. Probiotic bacteria, such as Lactobacillus fermentum and L. plantarum, have been found to inhibit biofilm formation; however little is known about the underlying mechanism. In this study, we tested the activity of supernatants produced by L...
October 28, 2016: BMC Microbiology
https://www.readbyqxmd.com/read/27774425/a-case-series-of-the-effects-of-a-novel-composition-of-a-traditional-natural-preparation-for-the-treatment-of-psoriasis
#14
A Michalsen, O Eddin, A Salama
The objective of this study was to assess the effectiveness of a specific composition of a traditional herbal preparation (DurrDerma) in adult patients with moderate to severe skin psoriasis. The preparation is a newly developed topical combination containing plant-based extracts traditionally used in skin disease as black cumin, olive oil, tea tree oil, cocoa butter completed by vitamin A and vitamin B12. We documented the effectiveness of the preparation in a first case series. A total of 12 patients (8 males and 4 females, 21-86 y) with manifest and treatment-resistant psoriasis were included and treated for 12 weeks...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27769412/prediction-of-fermentation-index-of-cocoa-beans-theobroma-cacao-l-based-on-color-measurement-and-artificial-neural-networks
#15
Noemí León-Roque, Mohamed Abderrahim, Luis Nuñez-Alejos, Silvia M Arribas, Luis Condezo-Hoyos
Several procedures are currently used to assess fermentation index (FI) of cocoa beans (Theobroma cacao L.) for quality control. However, all of them present several drawbacks. The aim of the present work was to develop and validate a simple image based quantitative procedure, using color measurement and artificial neural network (ANNs). ANN models based on color measurements were tested to predict fermentation index (FI) of fermented cocoa beans. The RGB values were measured from surface and center region of fermented beans in images obtained by camera and desktop scanner...
December 1, 2016: Talanta
https://www.readbyqxmd.com/read/27763364/standard-cocoa-transnational-networks-and-technoscientific-regimes-in-west-african-plantations
#16
Marta Macedo
In the early 1900s, an obscure Portuguese colony in the equatorial Atlantic rose as the world's leading cocoa producer. Cocoa from the island of São Tomé was grown on large plantations with indentured labor and high technological inputs. This technoscientific system, to control both plants and people, became the model for making an industry-suited cocoa, and the material evidence of the moral and economic virtues of the colonial plantation. Experts played a crucial role in building and putting into circulation such a system...
2016: Technology and Culture
https://www.readbyqxmd.com/read/27757264/hematological-changes-and-nitric-oxide-levels-accompanying-high-dose-artemether-lumefantrine-administration-in-male-guinea-pigs-effect-of-unsweetened-natural-cocoa-powder
#17
Isaac Julius Asiedu-Gyekye, Charles Antwi-Boasiako, Seth Oppong, Stella Arthur, Joseph Edusei Sarkodie
BACKGROUND: Unsweetened natural cocoa powder (UNCP), prepared after removal of the cocoa butter, is a common beverage in Ghana. It possesses antimalarial prophylactic property and has a beneficial effect on blood components. AIM: The aim of this study was to determine whether regular dietary supplement of UNCP mitigates high-dose (HD) artemether-lumefantrine (A-L)-induced hematological disorders and to determine the effect on nitric oxide (NO) levels. MATERIALS AND METHODS: Adult male guinea pigs (300 g - 350 g) were randomly divided into 5 groups of 6 guinea pigs each...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27725277/habitual-chocolate-intake-and-type-2-diabetes-mellitus-in-the-maine-syracuse-longitudinal-study-1975-2010-prospective-observations
#18
Georgina E Crichton, Merrill F Elias, Peter Dearborn, Michael Robbins
Compounds in cocoa and chocolate have established cardiovascular benefits, including beneficial effects on insulin resistance, a risk factor for type 2 diabetes mellitus. The aims of this study was to investigate relations between habitual chocolate intakes and diabetes mellitus. Cross-sectional and prospective analyses were undertaken on 953 community-dwelling participants (mean age 62 years, 59% women) from the Maine-Syracuse Longitudinal Study (MSLS). Habitual chocolate intakes, measured using a food frequency questionnaire, were related to prevalence of diabetes mellitus (cross-sectionally) and with risk of diabetes measured approximately five years later (prospectively)...
October 8, 2016: Appetite
https://www.readbyqxmd.com/read/27683874/cocoa-flavanol-intake-and-biomarkers-for-cardiometabolic-health-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
Xiaochen Lin, Isabel Zhang, Alina Li, JoAnn E Manson, Howard D Sesso, Lu Wang, Simin Liu
BACKGROUND: Cocoa flavanols may improve cardiometabolic health. Evidence from small short-term randomized clinical trials (RCTs) remains inconsistent, and large long-term RCTs testing the efficacy of cocoa flavanols are still lacking. OBJECTIVE: We performed a systematic review and meta-analysis of RCTs to quantify the effect of cocoa flavanol intake on cardiometabolic biomarkers. METHODS: We searched PubMed, Web of Science, and the Cochrane Library for RCTs that evaluated the effects of cocoa flavanols on biomarkers relevant to vascular disease pathways among adults...
November 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27682602/association-of-environmental-markers-with-childhood-type-1-diabetes-mellitus-revealed-by-a-long-questionnaire-on-early-life-exposures-and-lifestyle-in-a-case-control-study
#20
F Balazard, S Le Fur, S Valtat, A J Valleron, P Bougnères, Dominique Thevenieau, Corinne Fourmy Chatel, Rachel Desailloud, Hélène Bony-Trifunovic, Pierre-Henri Ducluzeau, Régis Coutant, Sophie Caudrelier, Armelle Pambou, Emmanuelle Dubosclard, Florence Joubert, Philippe Jan, Estelle Marcoux, Anne-Marie Bertrand, Brigitte Mignot, Alfred Penformis, Chantal Stuckens, Régis Piquemal, Pascal Barat, Vincent Rigalleau, Chantal Stheneur, Sylviane Fournier, Véronique Kerlan, Chantal Metz, Anne Fargeot-Espaliat, Yves Reznic, Frédérique Olivier, Iva Gueorguieva, Arnaud Monier, Catherine Radet, Vincent Gajdos, Daniel Terral, Christine Vervel, Djamel Bendifallah, Candace Ben Signor, Daniel Dervaux, Abdelkader Benmahammed, Guy-André Loeuille, Françoise Popelard, Agnès Guillou, Pierre-Yves Benhamou, Jamil Khoury, Jean-Pierre Brossier, Joachim Bassil, Sylvaine Clavel, Bernard Le Luyer, Pierre Bougnères, Françoise Labay, Isabelle Guemas, Jacques Weill, Jean-Pierre Cappoen, Sylvie Nadalon, Anne Lienhardt-Roussie, Anne Paoli, Claudie Kerouedan, Edwige Yollin, Marc Nicolino, Gilbert Simonin, Jacques Cohen, Catherine Atlan, Agnès Tamboura, Hervé Dubourg, Marie-Laure Pignol, Philippe Talon, Stéphanie Jellimann, Lucy Chaillous, Sabine Baron, Marie-Noëlle Bortoluzzi, Elisabeth Baechler, Randa Salet, Ariane Zelinsky-Gurung, Fabienne Dallavale, Etienne Larger, Marie Laloi-Michelin, Jean-François Gautier, Bénédicte Guérin, Laure Oilleau, Laetitia Pantalone, Céline Lukas, Isabelle Guilhem, Marc De Kerdanet, Marie-Claire Wielickzo, Mélanie Priou-Guesdon, Odile Richard, François Kurtz, Norbert Laisney, Déborah Ancelle, Guilhem Parlier, Catherine Boniface, Dominique Paris Bockel, Denis Dufillot, Berthe Razafimahefa, Pierre Gourdy, Pierre Lecomte, Myriam Pepin-Donat, Marie-Emmanuelle Combes-Moukhovsky, Brigitte Zymmermann, Marina Raoulx, Anne Gourdin Et Catherine Dumont
BACKGROUND: The incidence of childhood type 1 diabetes (T1D) incidence is rising in many countries, supposedly because of changing environmental factors, which are yet largely unknown. The purpose of the study was to unravel environmental markers associated with T1D. METHODS: Cases were children with T1D from the French Isis-Diab cohort. Controls were schoolmates or friends of the patients. Parents were asked to fill a 845-item questionnaire investigating the child's environment before diagnosis...
September 29, 2016: BMC Public Health
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