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Anish Bhuva

Heerajnarain Bulluck, Stefania Rosmini, Amna Abdel-Gadir, Steven K White, Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Esther Gonzalez-Lopez, Patricia Reant, Manish Ramlall, Ashraf Hamarneh, Alex Sirker, Anna S Herrey, Charlotte Manisty, Derek M Yellon, Peter Kellman, James C Moon, Derek J Hausenloy
BACKGROUND: Whether the remote myocardium of reperfused ST-segment elevation myocardial infarction (STEMI) patients plays a part in adverse left ventricular (LV) remodeling remains unclear. We aimed to use automated extracellular volume fraction (ECV) mapping to investigate whether changes in the ECV of the remote (ECVR emote) and infarcted myocardium (ECVI nfarct) impacted LV remodeling. METHODS AND RESULTS: Forty-eight of 50 prospectively recruited reperfused STEMI patients completed a cardiovascular magnetic resonance at 4±2 days and 40 had a follow-up scan at 5±2 months...
July 2016: Journal of the American Heart Association
Thomas A Treibel, Marianna Fontana, Viviana Maestrini, Silvia Castelletti, Stefania Rosmini, Joanne Simpson, Arthur Nasis, Anish N Bhuva, Heerajnarain Bulluck, Amna Abdel-Gadir, Steven K White, Charlotte Manisty, Bruce S Spottiswoode, Timothy C Wong, Stefan K Piechnik, Peter Kellman, Matthew D Robson, Erik B Schelbert, James C Moon
OBJECTIVES: The authors sought to generate a synthetic extracellular volume fraction (ECV) from the relationship between hematocrit and longitudinal relaxation rate of blood. BACKGROUND: ECV quantification by cardiac magnetic resonance (CMR) measures diagnostically and prognostically relevant changes in the extracellular space. Current methodologies require blood hematocrit (Hct) measurement-a complication to easy clinical application. We hypothesized that the relationship between Hct and longitudinal relaxation rate of blood (R1 = 1/T1blood) could be calibrated and used to generate a synthetic ECV without Hct that was valid, user-friendly, and prognostic...
January 2016: JACC. Cardiovascular Imaging
Heerajnarain Bulluck, Steven K White, Stefania Rosmini, Anish Bhuva, Thomas A Treibel, Marianna Fontana, Amna Abdel-Gadir, Anna Herrey, Charlotte Manisty, Simon M Y Wan, Ashley Groves, Leon Menezes, James C Moon, Derek J Hausenloy
BACKGROUND: Whether T1-mapping cardiovascular magnetic resonance (CMR) can accurately quantify the area-at-risk (AAR) as delineated by T2 mapping and assess myocardial salvage at 3T in reperfused ST-segment elevation myocardial infarction (STEMI) patients is not known and was investigated in this study. METHODS: 18 STEMI patients underwent CMR at 3T (Siemens Bio-graph mMR) at a median of 5 (4-6) days post primary percutaneous coronary intervention using native T1 (MOLLI) and T2 mapping (WIP #699; Siemens Healthcare, UK)...
2015: Journal of Cardiovascular Magnetic Resonance
Anish N Bhuva, Thomas A Treibel, Marianna Fontana, Anna S Herrey, Charlotte H Manisty, James C Moon
Cardiovascular magnetic resonance is an important tool for patient care and is the best test for myocardial structure and function. Ischemia and scar imaging also provide key insights and focus attention on heart muscle - the site of most cardiac diseases. New ways of measuring abnormal muscle have been developed, including T1 mapping. Abnormal signal can be distinguished either without contrast (native T1), or post-contrast (extracellular volume measurement). Large changes occur in rare diseases (cardiac amyloidosis, Anderson-Fabry disease and iron overload) even at an early stage, while more subtle changes are seen in diffuse fibrosis where a robust test would be of major impact...
December 2014: Expert Review of Cardiovascular Therapy
Anish N Bhuva, Harpreet K Lota
No abstract text is available yet for this article.
2011: BMJ: British Medical Journal
Marco Matteo Ciccone, Stefano Favale, Anish Bhuva, Pietro Scicchitano, Vito Caragnano, Cristina Lavopa, Giovanni De Pergola, Giuseppe Loverro
BACKGROUND: Women affected by polycystic ovary syndrome (PCOS) are known to be at higher risk of cardiovascular disease. The aim of this study was to identify the artery that first is affected by early pre-atherosclerotic changes in PCOS. METHODS: Twenty-nine women with PCOS aged 17 to 27 years and 26 healthy nonhyperandrogenic volunteers with regular menses (control women) aged 16 to 28 years were enrolled. All PCOS patients were overweight or obese (body mass index [BMI] > or = 25)...
2009: Vascular Health and Risk Management
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