keyword
MENU ▼
Read by QxMD icon Read
search

microbiota newborn

keyword
https://www.readbyqxmd.com/read/29333864/non-digestible-carbohydrates-in-infant-formula-as-substitution-for-human-milk-oligosaccharide-functions-effects-on-microbiota-and-gut-maturation
#1
Renate Akkerman, Marijke M Faas, Paul de Vos
Human milk (HM) is the golden standard for nutrition of newborn infants. Human milk oligosaccharides (HMOs) are abundantly present in HM and exert multiple beneficial functions, such as support of colonization of the gut microbiota, reduction of pathogenic infections and support of immune development. HMO-composition is during lactation continuously adapted by the mother to accommodate the needs of the neonate. Unfortunately, for many valid reasons not all neonates can be fed with HM and are either totally or partly fed with cow-milk derived infant formulas, which do not contain HMOs...
January 15, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29327435/impact-of-dietary-induced-precocious-gut-maturation-on-cecal-microbiota-and-its-relation-to-the-blood-brain-barrier-during-the-postnatal-period-in-rats
#2
N Marungruang, E Arévalo Sureda, A Lefrançoise, B Weström, M Nyman, O Prykhodko, F Fåk Hållenius
BACKGROUND: Precocious maturation of the gastrointestinal barrier (GIB) in newborn mammals can be induced by dietary provocation, but how this affects the gut microbiota and the gut-brain axis remains unknown. The objective of this study was to investigate effects of induced GIB maturation on gut microbiota composition and blood-brain barrier (BBB) permeability. METHODS: Suckling rats were studied at 72 h after gavage with phytohemagglutinin (PHA) or microbial protease (PT) to induce maturation of GIB...
January 12, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29325007/rifampicin-treatment-of-blattella-germanica-evidences-a-fecal-transmission-route-of-their-gut-microbiota
#3
Tania Rosas, Carlos García-Ferris, Rebeca Domínguez-Santos, Pablo Llop, Amparo Latorre, Andrés Moya
Eukaryotes have established symbiotic relationship with microorganisms, which enables them to accomplish functions that they cannot perform alone. In the German cockroach Blattella germanica, the obligate endosymbiont Blattabacterium coexists with a rich gut microbiota. The transmission of Blattabacterium is vertical but little is known about how the gut microbiota colonizes newborn individuals. In this study, we treated B. germanica populations with rifampicin, a broad-spectrum antibiotic, during two generations and analyzed gut bacterial composition and the Blattabacterium load in control and rifampicin-treated populations...
January 9, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29242550/diversity-of-vaginal-microbiota-increases-by-the-time-of-labor-onset
#4
Ekaterina Avershina, Silje Slangsvold, Melanie Rae Simpson, Ola Storrø, Roar Johnsen, Torbjørn Øien, Knut Rudi
Vaginal microbiota is an important early source of bacterial colonization for newborns. However, only a few small studies have investigated the composition of vaginal microbiota during labor. In this work, we analyzed vaginal swabs collected at 36 weeks gestation and at the onset of labor from 256 women participating in a randomized placebo-controlled study of probiotic supplementation for the prevention of atopic dermatitis in offspring. Although individuals' vaginal microbiota was stable over time, several bacterial families, which are characteristic of mixed community state type (CST) IV, were overrepresented in vaginal swabs sampled at labor...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29223548/co-occurrence-of-early-gut-colonization-in-neonatal-piglets-with-microbiota-in-the-maternal-and-surrounding-delivery-environments
#5
Xue Chen, Jumei Xu, Erdou Ren, Yong Su, Weiyun Zhu
The early development of gut microbiota plays a fundamental role in host health; so far, the main origins of the first colonization in newborn piglets are largely unclear. This study aimed to investigate the early development of gut microbiota in newborn piglets during lactation and their co-occurrence with microbes in the maternal and surrounding environments by Illumina MiSeq sequencing of 16S ribosomal RNA genes. The results showed that the microbial richness and diversity in piglets' feces (PF) significantly increased from birth to weaning (21 d)...
December 6, 2017: Anaerobe
https://www.readbyqxmd.com/read/29207565/delivery-mode-and-the-transition-of-pioneering-gut-microbiota-structure-composition-and-predicted-metabolic-function
#6
Noel T Mueller, Hakdong Shin, Aline Pizoni, Isabel C Werlang, Ursula Matte, Marcelo Z Goldani, Helena A S Goldani, Maria G Dominguez-Bello
Cesarean (C-section) delivery, recently shown to cause excess weight gain in mice, perturbs human neonatal gut microbiota development due to the lack of natural mother-to-newborn transfer of microbes. Neonates excrete first the in-utero intestinal content (referred to as meconium) hours after birth, followed by intestinal contents reflective of extra-uterine exposure (referred to as transition stool) 2 to 3 days after birth. It is not clear when the effect of C-section on the neonatal gut microbiota emerges...
December 4, 2017: Genes
https://www.readbyqxmd.com/read/29204137/microbial-mechanistic-insight-into-the-role-of-inulin-in-improving-maternal-health-in-a-pregnant-sow-model
#7
Pan Zhou, Yang Zhao, Pan Zhang, Yan Li, Taotao Gui, Jun Wang, Chao Jin, Lianqiang Che, Jian Li, Yan Lin, Shengyu Xu, Bin Feng, Zhengfeng Fang, De Wu
General consumption of "western diet" characterized by high refined carbohydrates, fat and energy intake has resulted in a global obesity epidemics and related metabolic disturbance even for pregnant women. Pregnancy process is accompanied by substantial hormonal, metabolic and immunological changes during which gut microbiota is also remarkably remodeled. Dietary fiber has been demonstrated to have a striking role in shifting the microbial composition so as to improve host metabolism and health in non-pregnant individuals...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29190745/colonization-with-escherichia-coli-ec-25-protects-neonatal-rats-from-necrotizing-enterocolitis
#8
Debi M Thomas, Brandon Bell, Stephanie Papillon, Patrick Delaplain, Joanna Lim, Jamie Golden, Jordan Bowling, Jin Wang, Larry Wang, Anatoly V Grishin, Henri R Ford
Necrotizing enterocolitis (NEC) is a significant cause of morbidity and mortality in premature infants; yet its pathogenesis remains poorly understood. To evaluate the role of intestinal bacteria in protection against NEC, we assessed the ability of naturally occurring intestinal colonizer E. coli EC25 to influence composition of intestinal microbiota and NEC pathology in the neonatal rat model. Experimental NEC was induced in neonatal rats by formula feeding/hypoxia, and graded histologically. Bacterial populations were characterized by plating on blood agar, scoring colony classes, and identifying each class by sequencing 16S rDNA...
2017: PloS One
https://www.readbyqxmd.com/read/29187842/low-microbial-diversity-and-abnormal-microbial-succession-is-associated-with-necrotizing-enterocolitis-in-preterm-infants
#9
Priscila T Dobbler, Renato S Procianoy, Volker Mai, Rita C Silveira, Andréa L Corso, Bruna S Rojas, Luiz F W Roesch
Despite increased efforts, the diverse etiologies of Necrotizing Enterocolitis (NEC) have remained largely elusive. Clinical predictors of NEC remain ill-defined and currently lack sufficient specificity. The development of a thorough understanding of initial gut microbiota colonization pattern in preterm infants might help to improve early detection or prediction of NEC and its associated morbidities. Here we compared the fecal microbiota successions, microbial diversity, abundance and structure of newborns that developed NEC with preterm controls...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29163938/understanding-biological-mechanisms-underlying-adverse-birth-outcomes-in-developing-countries-protocol-for-a-prospective-cohort-amanhi-bio-banking-study
#10
Abdullah H Baqui, Rasheda Khanam, Mohammad Sayedur Rahman, Aziz Ahmed, Hasna Hena Rahman, Mamun Ibne Moin, Salahuddin Ahmed, Fyezah Jehan, Imran Nisar, Atiya Hussain, Muhammad Ilyas, Aneeta Hotwani, Muhammad Sajid, Shahida Qureshi, Anita Zaidi, Sunil Sazawal, Said M Ali, Saikat Deb, Mohammed Hamad Juma, Usha Dhingra, Arup Dutta, Shaali Makame Ame, Caroline Hayward, Igor Rudan, Mike Zangenberg, Donna Russell, Sachiyo Yoshida, Ozren Polašek, Alexander Manu, Rajiv Bahl
Objectives: The AMANHI study aims to seek for biomarkers as predictors of important pregnancy-related outcomes, and establish a biobank in developing countries for future research as new methods and technologies become available. Methods: AMANHI is using harmonised protocols to enrol 3000 women in early pregnancies (8-19 weeks of gestation) for population-based follow-up in pregnancy up to 42 days postpartum in Bangladesh, Pakistan and Tanzania, with collection taking place between August 2014 and June 2016...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29137266/correlation-of-placental-microbiota-with-fetal-macrosomia-and-clinical-characteristics-in-mothers-and-newborns
#11
Jia Zheng, Xin-Hua Xiao, Qian Zhang, Li-Li Mao, Miao Yu, Jian-Ping Xu, Tong Wang
Substantial studies indicated that fetal macrosomia was associated with detrimental pregnancy outcomes, and increased susceptibility to metabolic diseases in later life. However, investigations into the association between placental microbiota and fetal macrosomia are limited. We aimed to profile the placental microbiota of fetal macrosomia and study whether they relate to clinical characteristics. Placenta samples were collected from fetal macrosomias and newborns with normal birth weight. The clinical characteristics, umbilical cord blood parameters were measured, and placental microbiota were sequenced and further analysed...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29133078/enteric-delivery-of-regenerating-family-member-3-alpha-alters-the-intestinal-microbiota-and-controls-inflammation-in-mice-with-colitis
#12
Marion Darnaud, Alexandre Dos Santos, Patrick Gonzalez, Sandrine Augui, Claire Lacoste, Christophe Desterke, Gert De Hertogh, Emma Valentino, Emilie Braun, Jinzi Zheng, Raphael Boisgard, Christel Neut, Laurent Dubuquoy, Franck Chiappini, Didier Samuel, Patricia Lepage, Francesca Guerrieri, Joel Doré, Christian Bréchot, Nicolas Moniaux, Jamila Faivre
BACKGROUND & AIMS: Paneth cell dysfunction causes deficiencies in intestinal C-type lectins and antimicrobial peptides, which leads to dysbiosis of the intestinal microbiota, alters the mucosal barrier, and promotes development of inflammatory bowel diseases. We investigated whether transgenic expression of the human regenerating family member 3 alpha gene (REG3A) alters the fecal microbiota and affects development of colitis in mice. METHODS: We performed studies with C57BL/6 mice that express human regenerating family member 3 alpha (hREG3A) in hepatocytes, via the albumin gene promoter...
November 10, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29118752/role-of-the-human-breast-milk-associated-microbiota-on-the-newborns-immune-system-a-mini-review
#13
REVIEW
Marco Toscano, Roberta De Grandi, Enzo Grossi, Lorenzo Drago
The human milk is fundamental for a correct development of newborns, as it is a source not only of vitamins and nutrients, but also of commensal bacteria. The microbiota associated to the human breast milk contributes to create the "initial" intestinal microbiota of infants, having also a pivotal role in modulating and influencing the newborns' immune system. Indeed, the transient gut microbiota is responsible for the initial change from an intrauterine Th2 prevailing response to a Th1/Th2 balanced one. Bacteria located in both colostrum and mature milk can stimulate the anti-inflammatory response, by stimulating the production of specific cytokines, reducing the risk of developing a broad range of inflammatory diseases and preventing the expression of immune-mediated pathologies, such as asthma and atopic dermatitis...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29029763/serotype-virulence-profile-antimicrobial-resistance-and-macrolide-resistance-determinants-in-streptococcus-agalactiae-isolates-in-pregnant-women-and-neonates-in-catalonia-spain
#14
Yuly López, Elena Parra, Virginio Cepas, Isabel Sanfeliú, Teresa Juncosa, Antonia Andreu, Mariona Xercavins, Josefa Pérez, Sergi Sanz, Andrea Vergara, Jordi Bosch, Sara Maria Soto
INTRODUCTION: Streptococcus agalactiae, or group B streptococci (GBS), is the main aetiological agent of early neonatal sepsis in developed countries. This microorganism belongs to the gastrointestinal tract microbiota wherefrom it can colonize the vagina and be vertically transmitted to the child either before or at birth, and subsequently cause infection in the newborn. Approximately, 50% of newborns born to women with GBS become colonized, with 1-2% developing early neonatal infection if no preventive intervention is performed...
October 10, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28990221/growth-performance-of-piglets-during-the-first-two-weeks-of-lactation-affects-the-development-of-the-intestinal-microbiota
#15
B Morissette, G Talbot, C Beaulieu, M Lessard
The aim of this study was to evaluate the effect of newborn piglet weight gain during the first 2 weeks of lactation on the luminal and mucosal microbiota of the ileum and colon. The microbiota from high-weight-gain (HWG) and low-weight-gain (LWG) 2-week-old piglets was characterized by amplicon length heterogeneity PCR (LH-PCR) and compared using diversity indices and multivariate statistical analyses. At birth, LWG piglets weighted in average 0.26 kg less than HWG piglets (p = .002). The weight difference between LWG and HWG piglets increased with time and reached 2...
October 9, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28988527/how-fucose-of-blood-group-glycotopes-programs-human-gut-microbiota
#16
REVIEW
S V Kononova
Formation of appropriate gut microbiota is essential for human health. The first two years of life is the critical period for this process. Selection of mutualistic microorganisms of the intestinal microbiota is controlled by the FUT2 and FUT3 genes that encode fucosyltransferases, enzymes responsible for the synthesis of fucosylated glycan structures of mucins and milk oligosaccharides. In this review, the mechanisms of the selection and maintenance of intestinal microorganisms that involve fucosylated oligosaccharides of breast milk and mucins of the newborn's intestine are described...
September 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28985873/intestinal-alkaline-phosphatase-deficiency-leads-to-dysbiosis-and-bacterial-translocation-in-the-newborn-intestine
#17
Jason Fawley, Shannon Koehler, Susan Cabrera, Vy Lam, Katherine Fredrich, Martin Hessner, Nita Salzman, David Gourlay
BACKGROUND: Intestinal alkaline phosphatase (IAP) has been shown to help maintain intestinal homeostasis. Decreased expression of IAP has been linked with pediatric intestinal diseases associated with bacterial overgrowth and subsequent inflammation. We hypothesize that the absence of IAP leads to dysbiosis, with increased inflammation and permeability of the newborn intestine. METHODS: Sprague-Dawley heterozygote IAP cross-matches were bred. Pups were dam fed ad lib and euthanized at weaning...
October 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28968427/evolution-in-fecal-bacterial-viral-composition-in-infants-of-two-central-african-countries-gabon-and-republic-of-the-congo-during-their-first-month-of-life
#18
Lionel Brazier, Eric Elguero, Claudine Kombila Koumavor, Nicolas Renaud, Franck Prugnolle, Frédéric Thomas, Simon Ategbo, Moyen Engoba, Obengui, Eric M Leroy, Patrick Durand, François Renaud, Pierre Becquart
Few studies have analyzed the gut microbiota of child in unindustrialized countries, but none during the first month of life. Stool samples were collected from healthy newborns in hospitals of Gabon (n = 6) and Republic of the Congo (n = 9) at different time points during the first month of life: meconium, day 2 (D02), day 7 (D07) and day 28 (D28). In addition, one fecal sample was collected from each mother after delivery. Metagenomic sequencing was performed to determine the bacterial communities, and multiplex real-time PCR was used to detect the presence of seven enteric viruses (rotavirus a, adenovirus, norovirus I and II, sapovirus, astrovirus, enterovirus) in these samples...
2017: PloS One
https://www.readbyqxmd.com/read/28942491/modulation-of-type-1-diabetes-risk-by-the-intestinal-microbiome
#19
REVIEW
Mikael Knip, Jarno Honkanen
PURPOSE OF REVIEW: The purpose of this review is to summarize potential modulations of the intestinal microbiome aimed at preventing or delaying progression to overt type 1 diabetes in the light of recently identified perturbations of the gut microbiota associated with the development of type 1 diabetes. RECENT FINDINGS: Accumulated data suggest that the gut microbiota is involved at two different steps in the evolution of type 1 diabetes. At the first step, the intestinal tract is colonized by a microbial community unable to provide an adequate education of the immune system...
September 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28936424/acid-stress-response-mechanisms-of-group-b-streptococci
#20
REVIEW
Sarah Shabayek, Barbara Spellerberg
Group B streptococcus (GBS) is a leading cause of neonatal mortality and morbidity in the United States and Europe. It is part of the vaginal microbiota in up to 30% of pregnant women and can be passed on to the newborn through perinatal transmission. GBS has the ability to survive in multiple different host niches. The pathophysiology of this bacterium reveals an outstanding ability to withstand varying pH fluctuations of the surrounding environments inside the human host. GBS host pathogen interations include colonization of the acidic vaginal mucosa, invasion of the neutral human blood or amniotic fluid, breaching of the blood brain barrier as well as survival within the acidic phagolysosomal compartment of macrophages...
2017: Frontiers in Cellular and Infection Microbiology
keyword
keyword
110058
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"