keyword
MENU ▼
Read by QxMD icon Read
search

Nocturnal asthma

keyword
https://www.readbyqxmd.com/read/29237390/chronopharmacokinetic-evaluation-of-budesonide-multiparticulate-systems
#1
Sowjanya Battu, Prasanna Raju Yalavarthi, G V Subbareddy, Uma Maheswara Rao, Jyothshna Devi Katamreddy, Harini Cowdary Vadlamudi
Poor oral absorption of budesonide limits design of its solid oral dosage form. With this context, multiparticulate pulsatile system of budesonide for chronotherapy of nocturnal asthma was aimed in this study. Initially, solid dispersions of budesonide (BD) using sodium starch glycolate (SSG) and guar gum (GG) were developed and characterized. Uniform sized non-pariel seeds (~400 µm) were coated with solid dispersions to obtain immediate (BMP) and controlled release pellets by solution layering technique. Pulsatile drug release pellets (BMPP) were obtained by coating the controlled release pellets with Eudragit L100 and RS 100...
December 12, 2017: Recent Patents on Drug Delivery & Formulation
https://www.readbyqxmd.com/read/29227026/the-prevalence-of-asthma-in-iranian-adults-the-first-national-survey-and-the-most-recent-updates
#2
Mohammad Reza Fazlollahi, Mehdi Najmi, Mojtaba Fallahnezhad, Nastaran Sabetkish, Anoushiravan Kazemnejad, Katayoon Bidad, Raheleh Shokouhi Shoormasti, Maryam Mahloujirad, Zahra Pourpak, Mostafa Moin
BACKGROUND: The worldwide increase in the prevalence of asthma has made it a major public-health concern. We aimed to identify the prevalence of asthma and asthma symptoms in adults living in urban and rural areas of Iran as a populated country with about 80 millions of residents. METHODS: This cross-sectional study was conducted to estimate the prevalence of asthma in adults between 20 to 44 years old in all provinces of Iran. Data were collected by personal interview via a standardized questionnaire (European Community Respiratory Health Survey (ECRHS)) between November 2015 and February 2016...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29196001/allium-tuberosum-antidiabetic-and-hepatoprotective-activities
#3
Xingli Tang, Opeyemi J Olatunji, Yifeng Zhou, Xilin Hou
Allium tuberosum (AT) is traditionally used for treating nocturnal emissions, abdominal pain, diarrhea, sexual dysfunction and asthma. This study aimed at investigating the antidiabetic and hepatoprotective activities of the butyl alcohol fraction from the methanolic extract of A. tuberosum. For the antidiabetic activity, rats were induced with diabetes by intraperitoneal injection of 150mg/kg alloxan and treated for 30days with AT extract (100, 200 and 400mg/kg). Animals were sacrificed after the study and the fasting blood glucose (FBG), triglyceride (TG), total cholesterol (TC), HDL, malondialdehyde (MDA) catalase, superoxide dismutase and glutathione levels were determined...
December 2017: Food Research International
https://www.readbyqxmd.com/read/29193245/review-article-gastro-oesophageal-reflux-disease-in-asthma-and-chronic-obstructive-pulmonary-disease
#4
REVIEW
C Broers, J Tack, A Pauwels
BACKGROUND: When gastro-oesophageal reflux is causing symptoms or lesions in the oesophagus, this is referred to as gastro-oesophageal reflux disease (GERD). GERD can manifest itself through typical symptoms (heartburn, regurgitation) or may lead to extra-oesophageal symptoms. Extra-oesophageal manifestations of GERD gained increasing attention over the last decade, especially respiratory disorders, because of the prevalent co-occurrence with GERD. The role of GERD in the pathogenesis of respiratory disorders has become a topic of intense discussion...
November 29, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29178682/real-life-clinical-use-of-symbicort%C3%A2-maintenance-and-reliever-therapy-for-asthmatic-patients-in-korea
#5
Sang Hoon Kim, Tae Bum Kim, Sang Heon Kim, Heung Woo Park, Sook Hee Song, Jae Won Jeong, Young Koo Jee, Sang Won Park, Mi Sun Kim, Ho Joo Yoon
The aim of this study was to examine the daily practice patterns of Symbicort® Maintenance and Reliever Therapy (SMART) in Korean asthmatic patients and to analyze clinical signs related to overuse. This study used an observational, multicenter, noninterventional, prospective, uncontrolled design for examining asthmatic patients prescribed SMART to assess the frequency and pattern of Symbicort® usage as a maintenance and reliever medication. The characteristics of patients showing signs of overuse (frequency of inhalation: 8 or more times per day) were also analyzed...
January 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29153413/an-objective-evaluation-of-nocturnal-cough-count-and-cough-pattern-in-children-with-psychogenic-cough
#6
Eri Imai, Kota Hirai, Yoshiko Mikami, Mariko Nukaga, Mayumi Enseki, Hideyuki Tabata, Masahiko Kato, Hiroyuki Mochizuki
Two patients with a chronic, barking cough were diagnosed with psychogenic cough. Using an original cough counter we studied the nocturnal cough count and pattern. While the number of coughs when awake was extremely high for both patients, the number of coughs was remarkably reduced during sleep, similar to an exacerbation of asthma. Moreover, the properties of the coughs when awake were clearly different from those of coughs during sleep. In conclusion, an objective examination using a cough counter was useful for the diagnosis, treatment and management of psychogenic cough...
November 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/29066920/study-of-the-clinical-and-functional-characteristics-of-asthmatic-children-with-obstructive-sleep-apnea
#7
Yen Nguyen-Hoang, Thuy Nguyen-Thi-Dieu, Sy Duong-Quy
BACKGROUND AND OBJECTIVE: The obstructive sleep apnea (OSA) is a common respiratory disorder in children, especially those at preschool and school ages. This study aimed to describe the characteristics of asthmatic children with OSA and the symptoms for a high risk of OSA. SUBJECTS AND METHODS: It was a prospective and descriptive study. The data of asthmatic children including medical history, clinical examination, blood tests, spirometry, exhaled nitric oxide (NO), and respiratory polygraphy were registered for analyses...
2017: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/29037301/asthma-symptoms-among-chinese-children-the-role-of-ventilation-and-pm10-exposure-at-school-and-home
#8
X-J Fan, C Yang, L Zhang, Q Fan, T Li, X Bai, Z-H Zhao, X Zhang, D Norback
SETTING: Respiratory symptoms in relation to environment in Taiyuan, China. OBJECTIVE: To study associations between school/home exposure and prevalence of respiratory symptoms and self-reported respiratory infections (RIs) among students. DESIGN: A total of 2134 pupils from 10 schools answered a questionnaire; air pollution at school was measured. RESULTS: The prevalence of current wheeze, daytime attacks of breathlessness, nocturnal cough, nocturnal respiratory symptoms and RI was respectively 4...
November 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28987691/pharyngeal-airspace-of-asthmatic-individuals-and-those-suffering-from-obstructive-sleep-apnea-syndrome-study-by-cbct
#9
Fátima Karoline Araújo Alves Dultra, Alana Tavares, Joaquim de Almeida Dultra, Cristina Salles, Iêda Margarida Crusoé-Rebelo, Inessa Barbosa, Adelmir Souza-Machado
PURPOSE: The objective of the present study was to comparatively evaluate the oropharyngeal space of patients with obstructive sleep apnea syndrome (OSA) and asthma by means of Cone Beam Computed Tomography (CBCT) images. MATERIAL AND METHODS: The study included individuals with OSA and asthma (n=10), with OSA and without asthma (n=6), asthmatics without OSA (n=6) and healthy individuals (n=25). All patients were evaluated by a pneumologist and submitted to a nocturnal polysomnogram...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28914352/impact-of-physical-activity-on-reporting-of-childhood-asthma-symptoms
#10
Benedicta Nneoma Nnodum, Meredith C McCormack, Nirupama Putcha, Seungyoung Hwang, Laura M Paulin, Emily P Brigham, Ashraf Fawzy, Karina Romero, Gregory B Diette, Nadia N Hansel
This study aims to determine the impact of physical activity on asthma symptom reporting among children living in an inner city. Among 147 children aged 5-12 years with physician-diagnosed asthma, we assessed asthma symptoms using twice-daily diaries and physical activity using the physical activity questionnaire for children during three 8-day periods (baseline, 3 and 6 months). Linear, logistic, and quasi-poisson regression models were used to determine the association between physical activity and asthma symptoms; adjusting for age, sex, race, BMI, caregiver's education, asthma severity, medication use, and season...
December 2017: Lung
https://www.readbyqxmd.com/read/28890019/allergic-sensitization-and-objective-measures-of-sleep-in-urban-school-aged-children-with-asthma
#11
Cynthia A Esteban, Robin S Everhart, Sheryl J Kopel, Robert B Klein, Daphne Koinis-Mitchell
BACKGROUND: Allergic sensitization is associated with increased child asthma morbidity and decreased pulmonary function. Nocturnal symptoms and/or awakenings typically are measured by self-report from diary data, whereas objective assessments of sleep in child asthma studies are lacking. OBJECTIVE: To investigate the association between increased allergic sensitization (number of positive allergy test results measured by skin prick test or specific immunoglobulin E) and sleep outcomes (sleep efficiency, sleep duration, and mean number of awakenings measured by actigraphy) in urban schoolchildren with persistent asthma...
September 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28831262/predictive-value-of-respiratory-symptoms-for-the-diagnosis-of-pollen-induced-seasonal-asthma-among-children-and-adults-in-inner-mongolia
#12
Ting Ting Ma, Yan Zhuang, Hai Ying Gong, Anthony Chauang Yii, Xue Yan Wang, Huan Zhong Shi
BACKGROUND: The diagnosis of asthma is made on the basis of variable respiratory symptoms and supported by objective evidence of variable airflow limitation. However, spirometry and bronchoprovocation tests may not be routinely available in resource-scarce settings or in the context of large-scale epidemiological studies. There is a gap in knowledge about the predictive value of respiratory symptoms for the diagnosis of pollen-induced asthma. OBJECTIVE: The aim of this study was to investigate the predictive value of self-reported respiratory symptoms for diagnosing pollen-induced asthma...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28814959/poor-sleep-is-highly-associated-with-house-dust-mite-allergic-rhinitis-in-adults-and-children
#13
Damien Leger, Bénédicte Bonnefoy, Bernard Pigearias, Bertrand de La Giclais, Antoine Chartier
BACKGROUND: Sleep disorders are often underreported to physicians by patients with allergies. This study aimed to characterize the sleep disorders associated with respiratory allergy to house dust mites (HDM) at the time of initiation of sublingual allergen immunotherapy (SLIT) in routine clinical practice. METHODS: This prospective, cross-sectional, observational study was conducted between November 2014 and March 2015 at 189 French trial sites and included 1750 participants suffering from HDM allergy who were initiating SLIT...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28799485/monoclonal-antibodies-a-review
#14
Surjit Singh, Nitish Kumar, Pradeep Dwiwedi, Jaykaran Charan, Rimplejeet Kaur, Preeti Sidhu, Vinay Kumar Chugh
Over the last three decades, monoclonal antibodies (MAbs) have made a striking transformation from scientific tools to powerful human therapeutics. Muromonab CD3 a murine MAb, was first FDA approved therapeutic MAb for prevention of kidney transplant rejection. Since its approval in 1986, there has been decline in the further application and approvals until the late 1990s when the first chimeric Mab, Rituximab was approved for the treatment of low grade B cell lymphoma in 1997. With the approval by licensing authorities of chimeric, followed by humanized and then fully human monoclonal antibodies, rate of approval and monoclonal antibodies available in the market for the treatment of various diseases has increased dramatically...
August 9, 2017: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/28759271/medication-use-sleep-and-caregiver-smoking-status-among-urban-children-with-asthma
#15
Samantha A Miadich, Robin S Everhart, Kristin E Heron, Caroline O Cobb
OBJECTIVE: Children living in urban settings from low-income, minority families are at a high risk for experiencing asthma morbidity. Environmental tobacco smoke (ETS, i.e., secondhand) exposure, typically from caregiver smoking, has been associated with increased quick-relief medication use and child nocturnal awakenings due to increased asthma symptoms as well as worse sleep quality in children with asthma. This study investigated the moderating role of caregiver smoking status on the association between quick-relief medication use and child's sleep quality in urban children with persistent asthma...
July 31, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28735503/association-between-allergic-disease-sleep-disordered-breathing-and-childhood-nocturnal-enuresis-a-population-based-case-control-study
#16
Jeng-Dau Tsai, Hsuan-Ju Chen, Min-Sho Ku, Shan-Ming Chen, Chih-Chuan Hsu, Min-Che Tung, Che-Chen Lin, Hsing-Yi Chang, Ji-Nan Sheu
BACKGROUND: Little is known about the associations between allergic disease, sleep-disordered breathing (SDB), and childhood nocturnal enuresis (NE). We examined whether allergic disease and SDB were associated with childhood NE. METHODS: Data were assessed from the 2007-2012 Taiwan National Health Insurance Research Database. We enrolled 4308 children aged 5-18 years having NE diagnosis and age- and sex-matched 4308 children as the control group. The odds ratios of NE were calculated to determine an association with preexisting allergic disease and SDB...
December 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28705995/reproducibility-of-airway-luminal-size-in-asthma-measured-by-hrct
#17
Robert H Brown, Robert J Henderson, Elizabeth A Sugar, Janet T Holbrook, Robert A Wise
Brown RH, Henderson RJ, Sugar EA, Holbrook JT, Wise RA, on behalf of the American Lung Association Airways Clinical Research Centers. Reproducibility of airway luminal size in asthma measured by HRCT. J Appl Physiol 123: 876-883, 2017. First published July 13, 2017; doi:10.1152/japplphysiol.00307.2017.-High-resolution CT (HRCT) is a well-established imaging technology used to measure lung and airway morphology in vivo. However, there is a surprising lack of studies examining HRCT reproducibility. The CPAP Trial was a multicenter, randomized, three-parallel-arm, sham-controlled 12-wk clinical trial to assess the use of a nocturnal continuous positive airway pressure (CPAP) device on airway reactivity to methacholine...
October 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28702854/gastroesophageal-reflux-disease-and-pulmonary-diseases-associated-with-aspergillosis-is-there-a-connection
#18
Maria N Gamaletsou, David W Denning
INTRODUCTION: We studied the relationship between GORD and allergic bronchopulmonary aspergillosis (ABPA), chronic pulmonary aspergillosis (CPA), or Aspergillus bronchitis. BACKGROUND: Gastroesophageal reflux disease (GORD) is well known to initiate or exacerbate pulmonary inflammatory conditions, inducing bronchial asthma and chronic obstructive lung disease. METHODS: We reviewed four patients referred with elevated Aspergillus serology markers and marked pulmonary symptoms for ABPA, CPA, and Aspergillus bronchitis, and discussed the underlying pathophysiological relationship with GORD...
December 2017: Mycopathologia
https://www.readbyqxmd.com/read/28695715/patient-reported-signs-of-dampness-at-home-may-be-a-risk-factor-for-chronic-rhinosinusitis-a-cross-sectional-study
#19
C Ahlroth Pind, M Gunnbjörnsdottír, A Bjerg, B Järvholm, B Lundbäck, A Malinovschi, R Middelveld, J Nilsson Sommar, D Norbäck, C Janson
BACKGROUND: An association between dampness at home and respiratory conditions has been convincingly demonstrated in children. Fewer studies have been performed in adults, and data are lacking for chronic rhinosinusitis (CRS). With a prevalence of 10.9% in Europe, CRS imposes a significant burden on quality of life, as well as economy. OBJECTIVE: Our aim was to study CRS and other respiratory conditions in relation to dampness at home in a representative sample of adults...
November 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28677827/the-overlaps-of-asthma-or-copd-with-osa-a-focused-review
#20
REVIEW
Robert L Owens, Madalina M Macrea, Mihaela Teodorescu
Asthma, chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are the most common respiratory disorders worldwide. Given demographic and environmental changes, prevalence for each is likely to increase. Although exact numbers are not known, based on chance alone, many people will be affected by both lower airways obstruction and concomitant upper airway obstruction during sleep. Some recent studies suggest that there is a reciprocal interaction, with chronic lung disease predisposing to OSA, and OSA worsening control and outcomes from chronic lung disease...
August 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
keyword
keyword
110028
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"