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stent implantation

Brian H Morray, Thomas K Jones, James Y Coe, Roland Gitter, Jose Zunzunegui Martinez, Daniel R Turner, Robert G Gray, Te-Hsin Lung, Darren P Berman, Daniel S Levi
OBJECTIVES: This study describes procedural and 1-year outcomes of the 16 mm Melody PB1016 valve in patients with dysfunctional RVOT conduits. BACKGROUND: The Melody PB1016 is a standard Melody valve produced from a 16 mm bovine jugular vein and is intended for deployment up to 20 mm. METHODS: This is a prospective, non-randomized, multicenter study of the procedural and short-term outcomes of Melody PB1016 TPV replacement within dysfunctional RVOT conduits...
November 12, 2018: Catheterization and Cardiovascular Interventions
Andrea Buono, Alessandro Maloberti, Irene M Bossi, Emanuela Piccaluga, Giacomo Piccalò, Jacopo A Oreglia, Antonella Moreo, Claudio F Russo, Fabrizio Oliva, Cristina Giannattasio
: Mycotic coronary aneurysm is a rare infective disease of arterial vessel walls. Their development could be linked to the presence of an infective endocarditis or could represent a primary infection at the site of an implanted intracoronary stent. Bacterial agents, particularly Staphylococcus aureus, are the most common etiological agents. Due to an aspecific clinical presentation and examination, diagnosis could be challenging. Multiple imaging techniques (both invasive and noninvasive) are often required to reach the final diagnosis...
November 9, 2018: Journal of Cardiovascular Medicine
Sebastien Hascoet, Robert Dalla Pozza, Jamie Bentham, Ronald Giacomo Carere, Majed Kanaan, Peter Ewert, Elzbieta Katarzyna Biernacka, Oliver Kretschmar, Cornelia Deutsch, Florence Lecerf, Anja Lehner, Marinos Kantzis, Jana Kurucova, Martin Thoenes, Peter Bramlage, Nikolaus A Haas
AIMS: Multiple surgical revisions are often necessary in individuals with congenital heart defects affecting the RVOT or pulmonary valve. There are no multicentre data on the feasibility and safety of percutaneous pulmonary valve implantation using the SAPIEN 3 (S3) transcatheter heart valve. METHODS AND RESULTS: Pulmonic S3 is an observational registry of patients undergoing PPVI with the S3 valve across centres in Europe and Canada. Data for 82 patients (mean age 27...
November 13, 2018: EuroIntervention
E Tautz, D Wagner, S Wiesemann, A Jonaszik, C Bode, T Wengenmayer, D Staudacher, P Biever, J Hoeppner, D Duerschmied
INTRODUCTION: Broncho-esophageal fistula formation is a rare complication of tuberculosis, most often seen in immunocompromised patients. METHODS AND RESULTS: In this paper, we report the case of a young non-immunocompromised refugee from Somalia diagnosed with open pulmonary tuberculosis complicated by extensive osseous involvement and a broncho-esophageal fistula with consecutive aspiration of gastric contents. The patient rapidly developed a severe acute respiratory distress syndrome (ARDS) requiring venovenous extracorporeal membrane oxygenation (ECMO) therapy for nearly 2 months...
November 11, 2018: Infection
George Kassimis, Tushar Raina
No abstract text is available yet for this article.
October 2018: Journal of Geriatric Cardiology: JGC
Adeline Schwein, Yannick Georg, Anne Lejay, Philippe Nicolini, Olivier Hartung, David Contassot, Fabien Thaveau, Frédéric Heim, Nabil Chakfe
There is a growing need for dedicated endovascular devices to treat pathologies affecting the venous system. However, because of a lack of research into venous diseases and treatments, the optimal design, material, and mechanical properties of venous stents remain unknown. Development of the ideal venous stent should be based on a thorough understanding of the underlying venous pathology. There are multiple venous diseases that differ from each other depending on their location (iliocaval, superior vena cava), mechanism (thrombotic versus nonthrombotic lesions), and chronicity...
July 2018: Methodist DeBakey Cardiovascular Journal
Yerin Kim, Jun Kyu Park, Jun-Hyuk Seo, Hyun-Seung Ryu, Kyung Seob Lim, Myung Ho Jeong, Dong Hoon Kang, Sang Won Kang
Although rapamycin is a well-known conformational inhibitor of mTORC1, it is now widely used for treating arterial restenosis. Various rapamycin analogues (rapalogue) have been made for applying to drug-eluting stents. Here we show that two major rapalogues, everolimus and biolimus, exert a differential effect on the mTORC1-mediated signaling pathways in vascular smooth muscle cells. In balloon-injured carotid arteries, both rapalogues strongly inhibit neointimal hyperplasia. Signaling pathway analyses reveal that everolimus exert cytotoxicity by increasing cellular reactive oxygen species and consequently reduce energy metabolism...
November 8, 2018: Scientific Reports
K Aydin, S Men, M Barburoglu, S Sencer, S Akpek
BACKGROUND AND PURPOSE: Coiling complex intracranial bifurcation aneurysms often necessitates the implantation of double stents in various configurations, such as Y-stent placement. Low-profile braided stents have been introduced recently to facilitate the endovascular treatment of wide-neck aneurysms. We aimed to investigate the feasibility, safety, efficacy, and durability of Y-stent-assisted coiling with double low-profile braided stents for the treatment of complex bifurcation aneurysms...
November 8, 2018: AJNR. American Journal of Neuroradiology
Song Lin, Xiaolin Ran, Xinhao Yan, Wenhua Yan, Qilong Wang, Tieying Yin, Jack G Zhou, Tingzhang Hu, Guixue Wang
Zinc (Zn) and its alloys have been proved to be promising candidate materials for biodegradable cardiovascular stents. In this study, a novel extruded Zn-0.02 Mg-0.02Cu alloy was prepared. Compared with pure Zn, the Zn-based alloy showed higher mechanical properties, and the Zn-based alloy could significantly accelerate Zn2+ release, reaching 0.61 ± 0.11 μg/mL at 15 days of immersion. In vitro biocompatibility studies demonstrated that the Zn-based alloy had excellent cytocompatibility and hemocompatibility, including low hemolysis rate (0...
November 8, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Guang Ming Tan, Ken Wai Kin Chi, Bryan Ping Yen Yan
OBJECTIVES: Endovascular treatment is indicated for the treatment of symptomatic thoracic central vein obstruction (TCVO) but is limited by high rates of restenosis and the need for re-intervention. The aim was to assess the safety and mid-term patency of a novel dedicated venous stent for the treatment of TCVO of benign aetiology. METHODS: This was a prospective single centre observational study of 20 patients (median age 65 years, 50% male) referred for the treatment of symptomatic chronic (>three months duration) TCVO between May 2016 and January 2018...
November 4, 2018: European Journal of Vascular and Endovascular Surgery
Babikir Kheiri, Mohammed Osman, Ahmed Abdalla, Tarek Haykal, Pranay V Pandrangi, Adam Chahine, Sahar Ahmed, Khansa Osman, Ghassan Bachuwa, Mustafa Hassan, Deepak L Bhatt
OBJECTIVES: This study aimed to evaluate the efficacy and safety of personalized genotype-guided selection of antiplatelet therapy versus standard of care in patients undergoing percutaneous coronary intervention (PCI). BACKGROUND: Clopidogrel is the most frequently used P2Y12 receptor antagonist in patients with coronary artery disease. However, genetic variations of clopidogrel are associated with inter-individual response variability which could limit its efficacy...
November 7, 2018: Catheterization and Cardiovascular Interventions
Magdalena Wawrzyńska, Iwona Bil-Lula, Anna Krzywonos-Zawadzka, Jacek Arkowski, Mikołaj Łukaszewicz, Dariusz Hreniak, Wiesław Stręk, Grzegorz Sawicki, Mieczysław Woźniak, Marek Drab, Kaja Frączkowska, Maciej Duda, Marta Kopaczyńska, Halina Podbielska, Dariusz Biały
Stainless steel 316L is a material commonly used in cardiovascular medicine. Despite the various methods applied in stent production, the rates of in-stent restenosis and thrombosis remain high. In this study graphene was used to coat the surface of 316L substrate for enhanced bio- and hemocompatibility of the substrate. The presence of graphene layers applied to the substrate was investigated using cutting-edge imaging technology: energy-filtered low-voltage FE-SEM approach, scanning electron microscopy (SEM), Raman spectroscopy, and atomic force microscopy (AFM)...
2018: BioMed Research International
Bongyeon Sohn, Jae Woong Choi, Ho Young Hwang, Kyung Hwan Kim, Ki-Bong Kim
Background: This study evaluated the early and long-term outcomes of surgical aortic valve replacement (AVR) in elderly patients in the era of transcatheter aortic valve implantation. Methods: Between 2001 and 2018, 94 patients aged ≥75 years underwent isolated AVR with stented bioprosthetic valves for aortic valve stenosis (AS). The main etiologies of AS were degenerative (n=63) and bicuspid (n=21). The median follow-up duration was 40.7 months (range, 0.6-174 months)...
October 2018: Korean Journal of Thoracic and Cardiovascular Surgery
Kuniyasu Ikeoka, Keita Okayama, Tetsuya Watanabe, Shinsuke Nanto, Yasushi Sakata, Shiro Hoshida
It is unclear whether arterial healing occurs beyond 1 year following paclitaxel-coated stent implantation in peripheral artery disease. An 81-year-old woman with superficial femoral artery disease underwent endovascular therapy with a paclitaxel-coated stent. An angiography 21 months later revealed peri-stent contrast staining in the superficial femoral artery, and optical frequency domain imaging demonstrated incomplete stent apposition with significant positive vascular remodeling. High-resolution angioscopy detected positive vascular wall remodeling and in-stent yellow plaque more clearly than conventional angioscopy...
September 25, 2018: Annals of Vascular Diseases
Gengfan Ye, Xiaoliang Yin, Ximeng Yang, Junjie Wang, Peng Qi, Jun Lu, Lijun Wang, Daming Wang
Drug-eluting stent (DES) is a potential endovascular treatment for patients with symptomatic intracranial atherosclerotic disease (sICAD). However, evidence regarding the treatment of ICAD with DES is lacking. We systematically searched Pubmed, Embase, Cochrane database (before 2017-12-21) for literature reporting the application of DES in the treatment of sICAD. The main outcomes were as follows: the incidence of any stroke or death within 30 days (perioperative complications), ischemic stroke in the territory of the qualifying artery beyond 30 days (long-term complications), in-stent restenosis rate (ISR) and symptomatic ISR during follow-up...
November 3, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Fan Zhao, Laijun Liu, Yang Yang, Fujun Wang, Lu Wang
A bstract: Polymeric bioresorbable stents (PBRSs) are considered the most promising devices to treat cardiovascular diseases. However, the mechanical weakness still hampers their application. In general, PBRSs are crimped into small sheathes and re-expanded to support narrowed vessels during angioplasty. Accordingly, one of the most significant requirements of PBRSs is to maintain mechanical efficacy after implantation. Although a little research has focused on commercial balloon-expanding PBRSs, a near-total lack has appeared on self-expanding PBRSs and their deformation mechanisms...
November 4, 2018: Materials
Martin Griva, Jiri Stastny, Petr Kopriva, Martin Slabak, Zdenek Coufal, Jiri Jarkovsky, Michal Svoboda, Tomas Salek, Lucie Sukupova, Milos Taborsky
BACKGROUND: While there have been a number of studies reporting the incidence and implications of elevated troponin levels after percutaneous coronary intervention (PCI), the body of information about the incidence, associations, and implications of elevated troponin levels following coronary angiography (CAG) is limited. MATERIALS AND METHODS: A total of 220 consecutive patients with stable coronary artery disease or intermediate or low-risk acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) were included in our study...
November 6, 2018: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
Yuan Ding, Li Zhongyou, Jiang Wentao, Zhang Yinci, Wang Zhenze, Chen Yu
Treating an abdominal aortic aneurysm (AAA) with a stent graft (SG) and a multilayer stent (MS) is a key technology in isolating flow fields. Clinically, dual stents (an SG in the proximal and an MS in the distal of AAA) are used for treatment of AAA, but only a few studies have examined the relationship between SG coverage and treatment effects. Through numerical simulation of the hemodynamics after SG and MS implantation, the SG coverage and position were simulated at 0% (0 mm), 25% (13.75 mm), 50% (27...
November 5, 2018: Scientific Reports
Kevin P Jackson
With expanding indications for cardiac resynchronization therapy and increased survival of patients with cardiovascular disease, the need for lead addition or revision in the presence of an existing implantable electronic device is likely to increase. Partial or complete venous occlusion is frequently encountered and can be a significant barrier to successful procedural outcomes. Percutaneous options, including subclavian venoplasty, can reduce the need for significantly more invasive and morbid procedures and can readily be learned by the implanting physician...
December 2018: Cardiac Electrophysiology Clinics
Mario Martínez-Galdámez, Jorge Escartín, Boris Pabón, Carlos Diaz, Roberto Martín-Reyes, Antonio Hermosín, Eduardo Crespo, Claudio Rodríguez, Gonzalo Monedero, Krishna Joshi, Demetrius K Lopes
BACKGROUND: The new generation of flow diverters includes a surface modification with a synthetic biocompatible polymer, which makes the device more biocompatible and less thrombogenic. Optical coherence tomography (OCT) can be used to visualize perforators, stent wall apposition, and intra-stent thrombus. Unfortunately real world application of this technology has been limited because of the limited navigability of these devices in the intracranial vessels. In this report, we share our experience of using 3D-printed neurovascular anatomy models to simulate and test the navigability of a commercially available OCT system and to show the application of this device in a patient treated with the new generation of surface modified flow diverters...
November 5, 2018: Interventional Neuroradiology
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