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psycho pharmacology

Anna M Aloisi, Vanna Berlincioni, Riccardo Torta, Rossella E Nappi, Cristina Tassorelli, Francesco Barale, Valentina Ieraci, Emanuele M Giusti, Giada Pietrabissa, Stefano Tamburin, Gian M Manzoni, Gianluca Castelnuovo
Pain is frequent in patients undergoing neurorehabilitation, but there is a number of still unanswered questions on this topic. The Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) was constituted with the purpose to identify the best practices that can be used in this context. In this article we summarize the existing evidence and recommendations provided by the ICCPN about the role of gender, psycho-social factors and anthropological-cultural dimensions on pain in neurorehabilitation. Sex, gender, psycho-social variables, anthropological and cultural features may influence pain expression, and its pharmacological and non-pharmacological outcome, but the role of these factors has not been consistently explored in neurorehabilitation...
September 16, 2016: European Journal of Physical and Rehabilitation Medicine
A Stansal, I Lazareth, M D'Ussel, P Priollet
Chronic vascular wounds are often painful. Pain can develop whatever the cause of the ulceration. It is well known during wound care but can occur at any time. The pain is often a complex phenomenon involving nociceptive pain, neuropathic pain, anxiety and emotional suffering, all directly related to the chronic disease. Care for the patient suffering from pain must take into consideration all of these aspects of the disease. The therapeutic strategy should rely on the use of different pharmacological agents, well-adapted local care using the different available analgesic tools and include psycho-affective care...
September 2016: Journal des Maladies Vasculaires
Agnès Weill-Chounlamountry, Jorge Alves, Pascale Pradat-Diehl
Posterior cortical atrophy (PCA) is a rare neurodegenerative condition characterized by progressive visual-perceptual deficits. Although the neurocognitive profile of PCA is a growing and relatively well-established field, non-pharmacological care remains understudied and to be widely established in clinical practice. In the present work we review the available literature on non-pharmacological approaches for PCA, such as cognitive rehabilitation including individual cognitive exercises and compensatory techniques to improve autonomy in daily life, and psycho-education aiming to inform people with PCA about the nature of their visual deficits and limits of cognitive rehabilitation...
August 16, 2016: World Journal of Clinical Cases
Manju Aswath, Lakshmi V Pandit, Karthik Kashyap, Raguram Ramnath
Persistent genital arousal disorder (PGAD) is a phenomenon, in which afflicted women experience spontaneous genital arousal, unresolved by orgasms and triggered by sexual or nonsexual stimuli, eliciting stress. The current case is a 40-year-old female who experienced such orgasms for about a month. Physical examination, investigations, and psychological testing were noncontributory. Carbamazepine (600 mg) was discontinued due to a lack of response. She improved significantly with supportive therapy. Various neuropsychological conditions, pelvic pathology, medications, etc...
July 2016: Indian Journal of Psychological Medicine
Maria S Vuorilehto, Tarja K Melartin, Kirsi Riihimäki, Erkki T Isometsä
BACKGROUND: Primary health care bears the main responsibility for treating depression in most countries. However, few studies have comprehensively investigated provision of pharmacological and psychosocial treatments, their continuity, or patient attitudes and adherence to treatment in primary care. METHODS: In the Vantaa Primary Care Depression Study, 1111 consecutive primary care patients in the City of Vantaa, Finland, were screened for depression with Prime-MD, and 137 were diagnosed with DSM-IV depressive disorders via SCID-I/P and SCID-II interviews...
September 15, 2016: Journal of Affective Disorders
Lieke J A Hassink-Franke, Mijnke M M Janssen, Guy Oehlen, Patricia A M van Deurzen, Jan K Buitelaar, Michel Wensing, Peter L B J Lucassen
BACKGROUND: Most general practitioners (GPs) do not feel comfortable with diagnosing and treating children with attention deficit hyperactivity disorder (ADHD). This is problematic since ADHD is a prevalent disorder and an active role of GPs is desired. In the Netherlands a collaborative ADHD programme was established, comprising of shortened diagnostic assessment in specialized mental healthcare followed by psycho-education in mental healthcare and pharmacological treatment by pre-trained GPs...
September 2016: European Journal of General Practice
E J M Pearson, M E Morris, M di Stefano, C E McKinstry
Cancer-related fatigue (CRF) is common and can be distressing for some survivors. There is increasing interest in measuring levels of CRF, highlighting its impact on quality of life. This review describes the nature and scope of evidence relating to interventions for CRF. Scoping review methodology was used to identify studies, extract data, collate and summarise results. Data were collated according to cancer tumour streams, stage of illness and the types of trial interventions. A total of 447 trials and 37 systematic reviews met the inclusion criteria...
June 2, 2016: European Journal of Cancer Care
E D Bazhanova, Yu O Kozlova, V N Anisimov, D S Sukhanov, D L Teply
Neurodegenerative changes and neuronal death are the basis for development of the nervous system aging. We investigated the mechanism of apoptosis of the sensorimotor cortex neurons of transgenic mice HER2/neu during aging, changes in the cortex function and the participation of exogenous neurometabolites (cytoflavin, piracetam) in regulation of neuronal death and locomotor and psycho-emotional status of mice. The level of apoptosis and expression of apoptosis markers (TUNEL, immunohistochemistry, Western blotting) in HER2/neu transgenic mice as compared to wild type mice (FBV line) were determined...
January 2016: Zhurnal Evoliutsionnoĭ Biokhimii i Fiziologii
Oded Hammerman, David Mostofsky, Yona Louria, Gal Ifergane, Yacov Ezra
BACKGROUND: Behavioral Medicine is an inter-disciplinary field concerned with the integration of behavioral and biomedical knowledge for the purposes of diagnosis, prevention, treatment and rehabilitation of conditions pertaining to health and illness. Behavioral treatments (such as: hypnosis, relaxation training, meditation, biofeedback and cognitive-behavioral therapy) have been shown to be effective in reducing physical symptoms as well as improving health-related behaviors and quality of life across a wide variety of illnesses, such as: chronic pain, somatic symptoms, diabetes, inflammatory bowel diseases, coronary heart disease and more...
February 2016: Harefuah
Ramon F Abarquez, Paul Ferdinand M Reganit, Carmen N Chungunco, Jean Alcover, Felix Eduardo R Punzalan, Eugenio B Reyes, Elleen L Cunanan
BACKGROUND: Chronic heart failure (HF) disease as an emerging epidemic has a high economic-psycho-social burden, hospitalization, readmission, morbidity and mortality rates despite many clinical practice guidelines' evidenced-based and consensus driven recommendations that include trials' initial-baseline data. OBJECTIVE: To show that the survival and hospitalization-free event rates in the reviewed chronic HF clinical practice guidelines' class I-A recommendations as initial HF drug therapy (IDT) is possibly a combination and 'start-to-end' synergistic effect of the add-on ('end') HF drug therapy (ADT) to the baseline ('start') HF drug therapy (BDT)...
March 2016: ASEAN Heart Journal: Official Journal of the ASEAN Federation of Cardiology
Stefano Porcelli, Oriana Bianchini, Giovanni De Girolamo, Eugenio Aguglia, Luciana Crea, Alessandro Serretti
OBJECTIVE: Relapses represent one of the main problems of schizophrenia management. This article reviews the clinical factors associated with schizophrenia relapse. METHODS: A research of the last 22 years of literature data was performed. Two-hundred nineteen studies have been included. RESULTS: Three main groups of factors are related to relapse: factors associated with pharmacological treatment, add-on psychotherapeutic treatments and general risk factors...
2016: International Journal of Psychiatry in Clinical Practice
Robert T M van Dongen, Han Samwel, Inge J J Arnts, Monique A H Steegers, Elbert A Joosten, Maarten van Kleef
Pain relief in patients with chronic neuropathic pain can be difficult to accomplish. If pharmacological treatment combined with a form of physical therapy and psychological support does not lead to improvement, nerve blocks and rehabilitation can be considered. Appropriately screened patients with persistent incapacitating pain may respond to neuromodulation. A specific form of this technique - spinal cord stimulation - delivers electric pulses via an implanted electrode connected to a battery in the epidural space around the spinal cord...
2015: Nederlands Tijdschrift Voor Geneeskunde
J B Noten, W M Verhoeven, S Tuinier, D Touw
The cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, including psychotropics. Its activity is determined by both genetic and environmental factors. The most important iso-enzymes for psychiatry in general are P450 IID6, 3A4 and 1A2. Knowledge about the involvement of these enzymes and biotransformation processes is mandatory because of the individual variability in their metabolic capacity. Regular measurement of plasmaconcentrations of (psycho)pharmacological compounds is therefore essential...
March 1999: Acta Neuropsychiatrica
Sujata Satapathy, Rajanikanta Swain, Vidhi Pandey, Chittaranjan Behera
Bestiality is a serious but less commonly reported form of animal cruelty occurring in a society. It is a punishable sexual offence in India. Bestiality has received little attention in recent psychiatric literature, and even though case reports have been published, an elaborate psychological assessment is often missing. This case report of 18 year old male presented here highlighted the importance of psychological assessment to emphasize on its implications for the further risk assessment of the person, family psycho-education and non-pharmacological intervention for bestialists...
January 2016: Indian Journal of Community Medicine
Oren Rom, Abraham Z Reznick
The history of stress research - milestones and people. Definitions and modern concepts of stress as well as the conflict between Hans Selye and the psychologists are described in this review. The molecular and physiological mechanisms of stress and their possible pharmacological intervention are introduced. The cycle of stress is presented as a new concept of the stress reaction, trying to bridge the gap between physiology and psychology. The cycle is a circular event in life, composed of 4 phases: (1) the resting ground phase, (2) the tension phase, (3) the response phase, and (4) the relief phase...
2016: Advances in Experimental Medicine and Biology
Carolina Inostroza Quezada, María Loreto Correa Venegas, Carolina Besoain Arrau, Alejandro Reinoso Medinelli, Macarena Velarde Lizama, María Teresa Valenzuela Mujica, Paula Bedregal García, Tamara Zubarew Gurtchin
INTRODUCTION: Chronic illnesses during adolescence are a big challenge for the patient, his or her family, and health care providers. The transition from paediatric health services to adult health services involves a programmed and planned transfer process of adolescent sufferers of chronic illnesses, in order to maintain a high quality of life and bio-psycho-social development. There is currently no transition model. The objective of the study is to understand the transition process from the perspective of hospitalised adolescents to collaborate towards the design of a model that meets the needs studied...
March 2016: Revista Chilena de Pediatría
Olga Sukhenko
BACKGROUND: Excessive alcohol consumption, a major health problem worldwide, affects about 6% of the United States population. Caring for patients with alcohol withdrawal syndrome in a hospital ward presents complex physiologic and psycho-social challenges which are best met with evidence-based practices. An academic medical center in the United States has been experiencing an increase in patients with alcohol withdrawal syndrome. However, gaps in clinician knowledge and infrastructure supporting the management of these patients still existed...
December 2015: JBI Database of Systematic Reviews and Implementation Reports
Philippe de Timary, Sophie Leclercq, Peter Stärkel, Nathalie Delzenne
The vast majority of studies that assessed the importance of biological factors for the development of psychiatric disorders focused on processes occurring at the brain level. Alcohol-dependence is a very frequent psychiatric disorder where psycho-pharmacological interventions are only of moderate efficacy. Our laboratory has recently described that a subpopulation of alcohol-dependent subjects, that accounted for approximately 40% of individuals tested, presented with an increased intestinal permeability, with a dysbiosis, with alterations in the metabolomic content of faeces--that could play a role in the increased permeability--and finally with a more severe profile of alcohol-dependence than the other non-dysbiotic subpopulation...
2015: Gut Microbes
Carla Perrone-Capano, Walter Adriani
No abstract text is available yet for this article.
2015: Frontiers in Behavioral Neuroscience
Amy T Peters, Leah W Shesler, Louisa Sylvia, Pedro Vieira da Silva Magalhaes, David J Miklowitz, Michael W Otto, Ellen Frank, Michael Berk, Darin D Dougherty, Andrew A Nierenberg, Thilo Deckersbach
OBJECTIVE: Individuals with bipolar disorder experience a disproportionately high incidence of medical co-morbidity and obesity. These health-related problems are a barrier to recovery from mood episodes and have been linked with unfavorable responses to pharmacological treatment. However, little is known about whether and how these characteristics affect responses to adjunctive psychotherapy. METHOD: Embedded in the Systematic Treatment Enhancement Program for Bipolar Disorder was a randomized controlled trial of psychotherapy for bipolar depression comparing the efficacy of intensive psychotherapy plus pharmacotherapy with collaborative care (a three-session psycho-educational intervention) plus pharmacotherapy...
July 2016: Australian and New Zealand Journal of Psychiatry
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