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https://www.readbyqxmd.com/read/29331600/a-real-world-study-on-the-genetic-cognitive-and-psychopathological-differences-of-obese-patients-clustered-according-to-eating-behaviours
#1
Mariarita Caroleo, Amedeo Primerano, Marianna Rania, Matteo Aloi, Valentina Pugliese, Fabio Magliocco, Gilda Fazia, Andrea Filippo, Flora Sinopoli, Marco Ricchio, Franco Arturi, Susana Jimenez-Murcia, Fernando Fernandez-Aranda, Pasquale De Fazio, Cristina Segura-Garcia
BACKGROUND: Considering that specific genetic profiles, psychopathological conditions and neurobiological systems underlie human behaviours, the phenotypic differentiation of obese patients according to eating behaviours should be investigated. The aim of this study was to classify obese patients according to their eating behaviours and to compare these clusters in regard to psychopathology, personality traits, neurocognitive patterns and genetic profiles. METHODS: A total of 201 obese outpatients seeking weight reduction treatment underwent a dietetic visit, psychological and psychiatric assessment and genotyping for SCL6A2 polymorphisms...
February 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29218451/the-trajectory-from-mood-to-obesity
#2
REVIEW
Judith Wurtman, Richard Wurtman
PURPOSE OF REVIEW: To describe and explain the relationships between mood disturbances and the development of obesity. RECENT FINDINGS: That depression, anxiety, PTSD, or severe stresses can promote obesity as a side-effect of the drugs used to treat them, or through "carbohydrate craving" to enhance brain serotonin synthesis and alleviate dysphoria by consuming foods that are rich in both carbohydrates and fats. That seasonal affective disorder and severe PMS can independently cause patients to overconsume foods rich in both carbohydrates and fats...
March 2018: Current Obesity Reports
https://www.readbyqxmd.com/read/29218021/the-effects-of-different-isocaloric-oral-nutrient-solutions-on-psychophysical-metabolic-cognitive-and-olfactory-function-in-young-male-subjects
#3
Stephan Bachlechner, Melanie Y Denzer-Lippmann, Jan Wielopolski, Marie Fischer, Andrea Buettner, Arndt Doerfler, Christof Schöfl, Gerald Münch, Johannes Kornhuber, Norbert Thürauf
Food intake influences human cognition, olfaction, hunger, and food craving. However, little research has been done in this field to elucidate the effects of different nutrients. Thus, the goal of our study was to investigate the effects of oral ingestion of different nutrient solutions on olfactory, cognitive, metabolic and psychophysical function. Twenty healthy men participated in our study employing a double-blind, cross-over, repeated measurement design. Participants were tested on four different study days...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29202335/sweet-taste-preference-in-binge-eating-disorder-a-preliminary-investigation
#4
Erica L Goodman, Lauren Breithaupt, Hunna J Watson, Christine M Peat, Jessica H Baker, Cynthia M Bulik, Kimberly A Brownley
Research suggests that individuals with high liking for sweets are at increased risk for binge eating, which has been minimally investigated in individuals with binge-eating disorder (BED). Forty-one adults (85% female, 83% white) with binge eating concerns completed a sweet taste test and measures of eating disorder behaviors and food cravings. A subset of participants with BED completed an oral glucose tolerance test (OGTT; N=21) and a 24-hour dietary recall (N=26). Regression models were used to compare highest sweet preferers (HSP [N=18]) to other sweet preferers (OSP [N=23]) and were used to assess associations between sweet taste preference and outcome variables...
January 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29163018/brain-networks-implicated-in-seasonal-affective-disorder-a-neuroimaging-pet-study-of-the-serotonin-transporter
#5
Martin Nørgaard, Melanie Ganz, Claus Svarer, Patrick M Fisher, Nathan W Churchill, Vincent Beliveau, Cheryl Grady, Stephen C Strother, Gitte M Knudsen
Background: Seasonal Affective Disorder (SAD) is a subtype of Major Depressive Disorder characterized by seasonally occurring depression that often presents with atypical vegetative symptoms such as hypersomnia and carbohydrate craving. It has recently been shown that unlike healthy people, patients with SAD fail to globally downregulate their cerebral serotonin transporter (5-HTT) in winter, and that this effect seemed to be particularly pronounced in female S-carriers of the 5-HTTLPR genotype. The purpose of this study was to identify a 5-HTT brain network that accounts for the adaption to the environmental stressor of winter in females with the short 5-HTTLPR genotype, a specific subgroup previously reported to be at increased risk for developing SAD...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29158252/food-addiction-high-glycemic-index-carbohydrates-and-obesity
#6
REVIEW
Belinda Lennerz, Jochen K Lennerz
BACKGROUND: Treatment success in obesity remains low, and recently food addiction has been delineated as an underlying etiologic factor with therapeutic relevance. Specifically, current treatment focuses on reduced food intake and increase of physical activity, whereas interventions for addiction encompass behavioral therapy, abstinence, and environmental interventions such as taxation, restrictions on advertising, and regulation of school menus. CONTENT: Here, we reviewed the pertinent literature on food addiction with a specific focus on the role of high-glycemic-index carbohydrates in triggering addictive symptoms...
January 2018: Clinical Chemistry
https://www.readbyqxmd.com/read/29145077/stability-of-the-diagnosis-of-seasonal-affective-disorder-in-a-long-term-prospective-study
#7
Marie-Laure Cléry-Melin, Philip Gorwood, Serge Friedman, Christian Even
BACKGROUND: Seasonal affective disorder (SAD) is mainly characterized by a seasonal pattern of depressive recurrences over the years. However, few studies have been conducted on the long-term course of patients with SAD, whose findings raised questions about the diagnosis stability over time. This study aimed to better characterize the diagnosis evolution, and determine prognosis markers. METHODS: An initial cohort of 225 outpatients diagnosed as having a SAD, was assessed at baseline (T1) for clinical symptoms and response to bright light therapy...
February 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29070709/increased-protein-consumption-during-the-day-from-an-energy-restricted-diet-augments-satiety-but-does-not-reduce-daily-fat-or-carbohydrate-intake-on-a-free-living-test-day-in-overweight-women
#8
Jess A Gwin, Kevin C Maki, Heather J Leidy
Background: Higher-protein (HP) energy-restriction diets improve weight management to a greater extent than normal-protein (NP) versions. Potential mechanisms of action with regard to assessment of eating behaviors across the day have not been widely examined during energy restriction. Objectives: The objectives of this study were to test whether the consumption of an HP energy-restriction diet reduces carbohydrate and fat intakes through improvements in daily appetite, satiety, and food cravings compared with NP versions and to test whether protein type within the NP diets alters protein-related satiety...
December 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28984747/thirty-versus-ten-day-diazepam-treatment-for-alcohol-detoxification-and-a-comparison-of-drinking-patterns-craving-and-anxiety-for-up-to-12-weeks-a-proof-of-concept-open-label-randomized-controlled-trial
#9
Nicolas Simioni, Julien Labreuche, Hélène Behal, Olivier Cottencin, Benjamin Rolland
PURPOSE: The aim of this study was to evaluate whether a prolonged detoxification treatment could decrease the relapse rate at 3 months after alcohol cessation in alcohol-dependent individuals through decreasing the levels of postdetoxification craving and anxiety. METHODS: Twenty-six adult patients with alcohol dependence (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision) who began an outpatient alcohol cessation program with an initial drinking goal of abstinence were enrolled in a 3-month, parallel, randomized (1:1 ratio), controlled, open-label, pilot trial...
October 3, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28901656/the-effects-of-seasonal-affective-disorder-and-alcohol-abuse-on-sleep-and-snoring-functions-in-a-population-based-study-in-finland
#10
Isabel Morales-Muñoz, Seppo Koskinen, Timo Partonen
Seasonal affective disorder (SAD) is a recurrent depressive disorder with a seasonal pattern. In addition to some specific symptoms such as sad mood, low energy or carbohydrate craving, this mood disorder is also characterized by the presence of sleeping problems and alcohol disorders. Interestingly, there is a strong link between alcohol use and sleeping deficits. Although previous studies have focused extensively on the sleep patterns in SAD patients and patients with alcohol use disorder (AUD), no research has yet been conducted on subjects with comorbid SAD and AUD...
September 13, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28859162/foods-are-differentially-associated-with-subjective-effect-report-questions-of-abuse-liability
#11
Erica M Schulte, Julia K Smeal, Ashley N Gearhardt
OBJECTIVES: The current study investigates which foods may be most implicated in addictive-like eating by examining how nutritionally diverse foods relate to loss of control consumption and various subjective effect reports. Subjective effect reports assess the abuse liabilities of substances and may similarly provide insight into which foods may be reinforcing in a manner that triggers an addictive-like response for some individuals. DESIGN: Cross-sectional. SETTING: Online community...
2017: PloS One
https://www.readbyqxmd.com/read/28712531/the-role-of-tryptophan-metabolism-and-food-craving-in-the-relationship-between-obesity-and-bipolar-disorder
#12
N Dalkner, M Platzer, S A Bengesser, A Birner, F T Fellendorf, R Queissner, A Painold, H Mangge, D Fuchs, B Reininghaus, H P Kapfhammer, S J Holasek, E Z Reininghaus
BACKGROUND & AIMS: Individuals with bipolar disorder (BD) have a significantly increased risk of obesity-related conditions. The imbalance between food intake and energy expenditure is assumed to be a major risk factor for obesity in BD. This study analyzed food craving in relation to anthropometric, metabolic, and neurobiological parameters in a well-characterized cohort of euthymic individuals with BD. METHODS: One-hundred-thirty-five patients completed the Food-Craving Inventory assessing four categories of food craving (fat, fast-food, sweets and carbohydrate craving)...
July 4, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28701972/the-effects-of-a-normal-rate-versus-a-slow-intervalled-rate-of-oral-nutrient-intake-and-intravenous-low-rate-macronutrient-application-on-psychophysical-function-two-pilot-studies
#13
Melanie Y Denzer-Lippmann, Stephan Bachlechner, Jan Wielopolski, Marie Fischer, Andrea Buettner, Arndt Doerfler, Christof Schöfl, Gerald Münch, Johannes Kornhuber, Norbert Thürauf
Stomach distension and energy per time are factors influencing satiety. Moreover, different rates of nutrient intake induce different stomach distension. The goal of our studies was to elucidate the influence of different oral rates of nutrient intake (normal rate versus slow intervalled rate; study I) and intravenous low rate macronutrient application (protein, carbohydrate, fat) or placebo (study II) on psychophysical function. The pilot studies investigated the effects of 1) study I: a mixed nutrient solution (1/3 protein, 1/3 fat, 1/3 carbohydrates) 2) study II: intravenous macronutrient infusions (protein, carbohydrate, fat) or placebo on psychophysical function (mood, hunger, food craving, alertness, smell intensity ratings and hedonic ratings) in human subjects...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28537802/seasonal-pattern-in-bipolar-disorders-and-cardio-vascular-risk-factors-a-study-from-the-face-bd-cohort
#14
MULTICENTER STUDY
Pierre A Geoffroy, Ophelia Godin, Diane Mahee, Chantal Henry, Valérie Aubin, Jean-Michel Azorin, Thierry Bougerol, Philippe Courtet, Sébastien Gard, Jean-Pierre Kahn, Christine Passerieux, Marion Leboyer, Frank Bellivier, Bruno Etain
Seasonal pattern (SP) and metabolic syndrome (MetS) are major contributors to poor outcome in bipolar disorders (BD). Patients with seasonal bipolar depression present increased appetite, carbohydrate cravings, weight gain, and hypersomnia, which can increase the development of MetS. MetS also appears to be associated with seasonal mood changes in the general population. This study examines whether a SP in BD is associated with an increased risk of MetS and its sub-components. One thousand four hundred and seventy-one outpatients with BD were systematically enrolled from 2009 to 2016...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28375878/carbohydrate-craving-not-everything-is-sweet
#15
REVIEW
Yue Ma, Risheka Ratnasabapathy, James Gardiner
PURPOSE OF REVIEW: Cravings for carbohydrates have been known about for hundreds of years but the mechanisms behind it were unclear. This review will highlight recent advances in our knowledge of mechanisms to detect carbohydrates in the diet. RECENT FINDINGS: Recent work has begun to identify the physiological mechanisms by which carbohydrates and glucose are detected and how this drives their intake. Recently, evidence has been found for systems that regulate carbohydrate and glucose intake via taste, hedonic, and homeostatic pathways...
July 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28364591/seasonal-affective-disorder-and-alcohol-abuse-disorder-in-a-population-based-study
#16
Isabel Morales-Muñoz, Seppo Koskinen, Timo Partonen
Seasonal affective disorder (SAD) is a recurrent major depressive disorder with a seasonal pattern, which is characterized by sad mood, low energy, longer sleep duration and carbohydrate craving. Furthermore, seasonal changes in mood and behavior may be closely related to alcohol use disorder (AUD). Nevertheless, there is scarce research on the study of cognitive impairments in SAD and AUD. We aimed to examine the relationship between the prevalence between SAD and AUD patients, and how cognitive functioning might be related to these variables...
July 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28364488/short-sleep-duration-is-associated-with-eating-more-carbohydrates-and-less-dietary-fat-in-mexican-american-children
#17
Suzanna M Martinez, Jeanne M Tschann, Nancy F Butte, Steve E Gregorich, Carlos Penilla, Elena Flores, Louise C Greenspan, Lauri A Pasch, Julianna Deardorff
Study Objective: Short sleep duration is a risk factor for childhood obesity. Mechanisms are unclear, but may involve selection of high carbohydrate foods. This study examined the association between estimated sleep duration and macronutrient intake as percentages of total energy among Mexican American (MA) 9-11 year olds. Methods: This cross-sectional study measured diet using two 24-hour recalls and estimated sleep duration using hip-worn accelerometry in MA children (n = 247) who were part of a cohort study...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28148682/dietary-protein-modifies-the-effect-of-the-mc4r-genotype-on-2-year-changes-in-appetite-and-food-craving-the-pounds-lost-trial
#18
RANDOMIZED CONTROLLED TRIAL
Tao Huang, Yan Zheng, Adela Hruby, Donald A Williamson, George A Bray, Yiru Shen, Frank M Sacks, Lu Qi
Background: The melanocortin-4 receptor (MC4R) plays a pivotal role in the regulation of appetite and eating behavior. Variants in the MC4R gene have been related to appetite and obesity. Objective: We aimed to examine whether weight-loss diets modified the effect of the "obesity-predisposing" MC4R genotype on appetite-related measures in a randomized controlled trial. Methods: A total of 811 overweight and obese subjects [25 ≤ body mass index (BMI; kg/m2 ) ≤ 40] aged 30-70 y were included in the 2-y POUNDS Lost (Preventing Overweight Using Novel Dietary Strategies) trial...
March 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28038436/examining-the-effects-of-cigarette-smoking-on-food-cravings-and-intake-depressive-symptoms-and-stress
#19
Ariana M Chao, Marney A White, Carlos M Grilo, Rajita Sinha
PURPOSE: This study examined the relationships among smoking status and total and specific types of food cravings (i.e., high-fats, sweets, fast-food fats, and complex carbohydrates/starches) and the influence of demographic, clinical, and psychological factors on this relationship. METHODS: Seven-hundred and twelve adults completed measures of food cravings, dietary intake, and smoking history. Heights and weights were measured. Data were analyzed using univariate and multivariate analyses while adjusting for demographic, clinical, and psychological covariates...
January 2017: Eating Behaviors
https://www.readbyqxmd.com/read/27855750/short-sleep-duration-is-associated-with-eating-more-carbohydrates-and-less-dietary-fat-in-mexican-american-children
#20
Suzanna M Martinez, Jeanne M Tschann, Nancy F Butte, Steve E Gregorich, Carlos Penilla, Elena Flores, Louise C Greenspan, Lauri A Pasch, Julianna Deardorff
STUDY OBJECTIVE: Short sleep duration is a risk factor for childhood obesity. Mechanisms are unclear, but may involve selection of high carbohydrate foods. This study examined the association between estimated sleep duration and macronutrient intake as percentages of total energy among Mexican American (MA) 9-11 year olds. METHODS: This cross-sectional study measured diet using two 24-hour recalls and estimated sleep duration using hip-worn accelerometry in MA children (n=247) who were part of a cohort study...
November 14, 2016: Sleep
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