Ryan S Huang, Kelly R McMahon, Stella Wang, Hayton Chui, Asaf Lebel, Jasmine Lee, Vedran Cockovski, Shahrad Rod Rassekh, Kirk R Schultz, Tom D Blydt-Hansen, Geoffrey D E Cuvelier, Cherry Mammen, Maury Pinsk, Bruce C Carleton, Ross T Tsuyuki, Colin J D Ross, Ana Palijan, Michael Zappitelli
BACKGROUND: Urine kidney injury biomarkers measured during cisplatin therapy may identify patients at risk for adverse subsequent kidney outcomes. We examined relationships between tubular injury biomarkers collected early (early visit [EV]: first or second cisplatin cycle) and late (late visit [LV]: last or second-last cisplatin cycle) during cisplatin therapy, with 3-month post-cisplatin chronic kidney disease (CKD) and hypertension. METHODS: We analyzed data from the Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment Nephrotoxicity Study: twelve-center prospective cohort study of 159 children receiving cisplatin...
April 26, 2024: Kidney360