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Doppler physics

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https://www.readbyqxmd.com/read/30242049/angiopoietin-tie2-axis-regulates-the-age-at-injury-cerebrovascular-response-to-traumatic-brain-injury
#1
Thomas R Brickler, Amanda Hazy, Fernanda Guilhaume Correa, Rujuan Dai, Elizabeth J A Kowalski, Ross Dickerson, John Chen, Xia Wang, Paul D Morton, Abby Whittington, Ansar Ahmed, Michelle H Theus
While age-at-injury influences chronic recovery from traumatic brain injury (TBI), the differential effects of age on early outcome remain understudied. Using a male murine model of moderate contusion injury, we investigated the underlying mechanism(s) regulating the distinct response between juvenile and adult TBI. We demonstrate similar biomechanical and physical properties of naïve juvenile and adult brains. However, following controlled cortical impact (CCI), juvenile mice displayed reduced cortical lesion formation, cell death and behavioral deficits at 4 and 14 days...
September 21, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/30236749/clinical-patient-reported-and-ultrasound-outcomes-from-an-open-label-12-week-observational-study-of-certolizumab-pegol-in-spanish-patients-with-rheumatoid-arthritis-with-or-without-prior-anti-tnf-exposure
#2
Francisco J Blanco, Esteban Rubio-Romero, Raimon Sanmartí, César Díaz-Torné, Pablo Talavera, Jochen Dunkel, Esperanza Naredo
OBJECTIVES: To assess the effectiveness and safety of certolizumab pegol (CZP) in Spanish patients with RA. MATERIALS AND METHODS: SONAR (NCT01526434), a 12-week, open-label, prospective, observational, multicenter study. Patients with active RA for ≥3 months, according to ACR criteria, were treated with CZP (400mg at Weeks 0, 2 and 4, then 200mg every 2 weeks). The primary effectiveness endpoint was change from baseline (CFB) in Health Assessment Questionnaire-Disability Index (HAQ-DI) at Week 12...
September 17, 2018: Reumatología Clinica
https://www.readbyqxmd.com/read/30222240/physical-examination-to-screen-for-peripheral-artery-disease-in-a-defined-primary-care-population-a-diagnostic-accuracy-study
#3
Ángel Herráiz-Adillo, Olga Piñar-Serrano, Julián Ángel Mariana-Herráiz, Vicente Martínez-Vizcaíno, Diana Patricia Pozuelo-Carrascosa, Blanca Notario-Pacheco
INTRODUCTION: Peripheral arterial disease (PAD) is an underdiagnosed prevalent disease which implies high cardiovascular risk. Professionals usually depend on physical examination to screen for PAD. OBJECTIVE: To assess the diagnostic accuracy of physical examination to screen for PAD in a rural Primary Care population and to evaluate the nurse-physician level of agreement in pedal pulse palpation. METHODS: Diagnostic accuracy study in which two experienced professionals (physician-nurse) prospectively performed pedal pulse palpation (grading as absent, reduced, normal, or bounding), femoral bruit auscultation and calf circumference (index tests) comparing with Doppler ABI (reference test, positive cut-off: 0...
September 17, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/30220181/-clinical-analysis-of-orbital-ectopic-meningiomas
#4
X M Huang, D Wang, J Y Lin, D R Tang, F Y Sun
Objective: To investigate the clinical features, imaging features, diagnoses and therapeutic regimens of orbital ectopic meningiomas. Methods: A retrospective study. All the clinical data of 10 patients (10 eyes) with orbital ectopic meningiomas were analyzed retrospectively from August 1999 to October 2016. They included imaging data such as color Doppler ultrasound, CT and MRI, and information of diagnosis, pathology, therapeutic regimen and prognosis. Results: The age of orbital ectopic meningiomas was 7 to 68 years old...
September 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/30213764/impact-of-hydrodynamics-on-ipsc-derived-cardiomyocyte-differentiation-processes
#5
Jasmin J Samaras, Bernardo Abecasis, Margarida Serra, Andrea Ducci, Martina Micheletti
Cardiomyocytes (CMs), derived from pluripotent stem cells (PSCs), have the potential to be used in cardiac repair. Addition of physical cues, such as electrical and mechanical stimulations, have proven to significantly effect morphology, density, cardiogenesis, maturity and functionality of differentiated CMs. This work combines rigorous fluid dynamics investigation and flow frequency analysis with iPSC differentiation experiments to identify and quantify the flow characteristics leading to a significant increase of differentiation yield...
September 10, 2018: Journal of Biotechnology
https://www.readbyqxmd.com/read/30213237/excessive-release-of-endogenous-neuropeptide-y-into-cerebrospinal-fluid-after-treatment-of-spontaneous-subarachnoid-haemorrhage-and-its-possible-impact-on-self-reported-neuropsychological-performance-results-of-a-prospective-clinical-pilot-study-on-good-grade
#6
Elisabeth Bründl, Martin Proescholdt, Petra Schödel, Sylvia Bele, Julius Höhne, Florian Zeman, Eva-Maria Stoerr, Alexander Brawanski, Karl-Michael Schebesch
OBJECTIVES: Neuropsychological dysfunction after treatment of spontaneous subarachnoid haemorrhage (sSAH) is common but underreported. The vasoconstrictor neuropeptide Y (NPY) is excessively released after sSAH and in psychiatric disorders. We prospectively analysed the treatment-specific differences in the secretion of endogenous cerebrospinal fluid (CSF) NPY during the acute stage after sSAH and its impact on cognitive processing. METHODS: A total of 26 consecutive patients (f:m = 13:8; mean age 50...
September 14, 2018: Neurological Research
https://www.readbyqxmd.com/read/30192614/thermal-temperature-measurements-of-inertial-fusion-implosions
#7
L C Jarrott, B Bachmann, T Ma, L R Benedetti, F E Field, E P Hartouni, R Hatarik, N Izumi, S F Khan, O L Landen, S R Nagel, R Nora, A Pak, J L Peterson, M B Schneider, P T Springer, P K Patel
Accurate measurement of the thermal temperature in inertially confined fusion plasmas is essential for characterizing ignition performance and validating the basic physics understanding of the stagnation conditions. We present experimental results from cryogenic deuterium-tritium implosions on the National Ignition Facility using a differential filter spectrometer designed to measure the thermal electron temperature from x-ray continuum emission from the stagnated plasma. Furthermore, electron temperature measurements, used in conjunction with the Doppler-broadened DT neutron spectra, allow one to infer the partition of energy in the hot spot between internal energy and unconverted kinetic energy...
August 24, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30184293/rate-of-left-ventricular-pressure-change-by-doppler-echocardiography-in-dogs-with-chronic-mitral-valve-disease-at-different-stages-of-congestive-heart-failure
#8
Yun-Hye Kim, Gum-Joo Choi, Chul Park
Although the major pathological feature of chronic mitral valve disease is mitral regurgitation, myocardial dysfunction has been suggested to be present in dogs with chronic mitral valve disease. However, accurate assessment of myocardial function remains challenging. Doppler-derived rate of left ventricular pressure change is a simple, less load-dependent method for evaluating myocardial function. We aimed to evaluate Doppler-derived rate of left ventricular pressure change for assessing myocardial function in different stages of dogs with chronic mitral valve disease...
September 5, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/30157362/-selective-embolization-for-arterial-priapism-a-report-of-5-cases
#9
Min-Kai Xie, Da-Chao Zheng, Chong Liu, Hai-Jun Yao, Zhong Wang
Objective: To introduce our experience in the treatment of arterial priapism by superselective embolization. METHODS: This study included 5 cases of perineal trauma-induced arterial erectile dysfunction treated in our departmentbetween February 2011 and May 2015, all failingpreviously to respond to 3 weeks of conservative treatment. The patients were aged 25-47 (mean 35) years, with the onset of arterial priapism at 2-5 days after trauma, and all subjected to physical examination, blood gas analysis, color Doppler ultrasonography of the corpora cavernosum, and IIEF-5 scoring...
2018: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/30142810/treatment-of-rosacea-using-acupuncture-for-improving-the-local-skin-microcirculation-a-case-report
#10
Yacen Gao, Weipeng Lin, Sisi Zhou, Guoqi Shi, Jun He, Yongjun Chen
RATIONALE: Rosacea is an irritating disease that affects patients' health and life quality. The current treatments for rosacea have limited efficacy and are generally not satisfying most patients. This report presents a patient diagnosed with rosacea who was treated with acupuncture to a satisfactory effect. Laser Doppler was used to measure the local blood perfusion of the nose before, during, and after acupuncture treatment. The Dermatology Life Quality Index (DLQI) was used to measure the impact of rosacea on the quality of the patient's life...
August 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30139649/echocardiographic-variables-in-healthy-north-american-salukis
#11
T A Kurosawa, M D Sist, R A Sanders
INTRODUCTION: To report normal echocardiographic variables from a population of healthy Salukis in North America. ANIMALS: The study included 83 healthy adult Salukis from North America with structurally normal hearts. METHODS: All animals underwent a full physical examination and two-dimensional, M-mode, and Doppler echocardiography using the right parasternal and left apical views with the left ventricular volumes calculated using the Simpson's method of discs...
August 20, 2018: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/30123375/is-it-possible-to-recover-cardiac-functions-after-total-knee-arthroplasty
#12
Aydın Arslan, Bilal Çuglan, Bülent Özkurt, Ali Utkan, Mehmet Fatih Korkmaz, Tuba Tülay Koca, Resit Sevimli
Background: Patients suffering from knee osteoarthritis lead a less active life than their healthy peers. It is well known that insufficient physical activity is the most common cause of chronic diseases. However, there is not enough research to enlighten the effect of increased functional capacity on cardiac functions after Total Knee Arthroplasty (TKA). This study aimed to investigate whether the orthopedic surgeons can predict that the patients will be healthier after TKA in terms of cardiac functions or not? Methods: 109 patients who underwent TKA were prospectively followed for one year...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/30121867/determinants-of-exercise-performance-in-children-and-adolescents-with-repaired-tetralogy-of-fallot-using-stress-echocardiography
#13
Shivani M Bhatt, Okan U Elci, Yan Wang, Elizabeth Goldmuntz, Michael McBride, Stephen Paridon, Laura Mercer-Rosa
Exercise performance is variable and often impaired in patients with repaired tetralogy of Fallot (rTOF). We sought to identify factors associated with exercise performance by comparing high to low performers on cardiopulmonary exercise testing (CPET) in patients with rTOF. We conducted a cross-sectional study of subjects presenting for CPET who underwent echocardiograms at rest and peak exercise. Patients with pacemakers and arrhythmias were excluded. Right ventricular (RV) global longitudinal strain was used as a measure of systolic function...
August 18, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/30121699/musculoskeletal-ultrasound-for-predicting-remission-in-patients-with-rheumatoid-arthritis-results-from-a-1-year-prospective-study
#14
Tanya Sapundzhieva, Rositsa Karalilova, Anastas Batalov
To assess the role of musculoskeletal ultrasound as a predictor for the achievement of DAS28 remission in patients with rheumatoid arthritis (RA). One hundred and forty-one patients underwent physical and ultrasound examination at five visits (at baseline and after 1, 3, 6 and 12 months). Patients were divided into two groups according to the type of treatment, which involved synthetic (sDMARDs) and biologic (bDMARDs) disease-modifying antirheumatic drugs. Ultrasound assessment of the wrist, second and third metacarpophalangeal, second and third proximal interphalangeal joint, second and fifth metatarsophalangeal joint (the German US7 score) was performed on gray scale (GS) and on power Doppler ultrasound (PDUS)...
October 2018: Rheumatology International
https://www.readbyqxmd.com/read/30116303/best-practice-in-the-diagnosis-and-treatment-of-varicocele-in-children-and-adolescents
#15
REVIEW
Matthew R Macey, Ryan C Owen, Sherry S Ross, R Matthew Coward
A varicocele is an abnormal dilation of the pampiniform plexus of veins in the scrotum which begins at puberty in approximately 15% of males. Although common in the general population and often asymptomatic, varicoceles are associated with gonadal dysfunction including testicular atrophy, infertility, and hypogonadism in a subset of men diagnosed later in life. Because of the high prevalence and uncertain pathogenesis, definitive management guidelines for varicoceles diagnosed in the pediatric and adolescent population remain poorly defined...
September 2018: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/30111998/genotoxicity-of-copper-and-nickel-nanoparticles-in-somatic-cells-of-drosophila-melanogaster
#16
Erico R Carmona, Alba García-Rodríguez, Ricard Marcos
Copper and nickel nanoparticles (Cu-NPs and Ni-NPs, respectively) are used in a variety of industrial applications, such as semiconductors, catalysts, sensors, and antimicrobial agents. Although studies on its potential genotoxicity already exist, few of them report in vivo data. In the present study we have used the wing-spot assay in Drosophila melanogaster to determine the genotoxic activity of Cu-NPs and Ni-NPs, and these data have been compared with those obtained with their microparticle forms (MPs). Additionally, a complete physical characterization of NPs using transmission electronic microscopy (TEM), dynamic light scattering (DLS), and laser Doppler velocimetry (LDV) techniques was also performed...
2018: Journal of Toxicology
https://www.readbyqxmd.com/read/30094592/breast-ultrasound-recommendations-for-information-to-women-and-referring-physicians-by-the-european-society-of-breast-imaging
#17
Andrew Evans, Rubina M Trimboli, Alexandra Athanasiou, Corinne Balleyguier, Pascal A Baltzer, Ulrich Bick, Julia Camps Herrero, Paola Clauser, Catherine Colin, Eleanor Cornford, Eva M Fallenberg, Michael H Fuchsjaeger, Fiona J Gilbert, Thomas H Helbich, Karen Kinkel, Sylvia H Heywang-Köbrunner, Christiane K Kuhl, Ritse M Mann, Laura Martincich, Pietro Panizza, Federica Pediconi, Ruud M Pijnappel, Katja Pinker, Sophia Zackrisson, Gabor Forrai, Francesco Sardanelli
This article summarises the information that should be provided to women and referring physicians about breast ultrasound (US). After explaining the physical principles, technical procedure and safety of US, information is given about its ability to make a correct diagnosis, depending on the setting in which it is applied. The following definite indications for breast US in female subjects are proposed: palpable lump; axillary adenopathy; first diagnostic approach for clinical abnormalities under 40 and in pregnant or lactating women; suspicious abnormalities at mammography or magnetic resonance imaging (MRI); suspicious nipple discharge; recent nipple inversion; skin retraction; breast inflammation; abnormalities in the area of the surgical scar after breast conserving surgery or mastectomy; abnormalities in the presence of breast implants; screening high-risk women, especially when MRI is not performed; loco-regional staging of a known breast cancer, when MRI is not performed; guidance for percutaneous interventions (needle biopsy, pre-surgical localisation, fluid collection drainage); monitoring patients with breast cancer receiving neo-adjuvant therapy, when MRI is not performed...
August 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/30093546/eighty-two-year-old-man-with-a-systolic-murmur
#18
Daniel F Kupsky, Karthikeyan Ananthasubramaniam, James Lee
CLINICAL INTRODUCTION: An 82-year-old man with a history of coronary artery bypass surgery, hypertension and small bowel gastrointestinal stromal tumour underwent cardiac risk evaluation prior to surgical resection of his tumour. He was asymptomatic from a cardiovascular perspective, but his activity level was less than four metabolic equivalents. Physical examination was notable for a 2/6 systolic murmur at the apex. ECG showed sinus rhythm. A transthoracic echocardiogram was performed (figure 1 and online supplementary video 1)...
August 9, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30093542/woman-in-her-50s-with-shortness-of-breath-on-exertion
#19
Takao Konishi, Hironori Murakami, Shinya Tanaka
CLINICAL INTRODUCTION: A 59-year-old woman visited an outpatient cardiology clinic due to shortness of breath on exertion. Physical examination showed no significant abnormality of vital signs. A III/VI systolic murmur was heard on the fourth intercostal space at the right sternal border. The majority of laboratory tests were normal. Chest X-ray showed a curved vessel shadow (figure 1A). Initial transthoracic echocardiography showed abnormal blood flow into the inferior vena cava (IVC) in the subxiphoid long axis view (figure 1B) and mild right heart dilatation (online supplementary figure 1)...
August 9, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/30078732/successful-use-of-an-inflatable-penile-prosthesis-for-the-treatment-of-distal-deficiency-of-the-tunica-albuginea-and-cavernous-tissue
#20
Nahid Punjani, Patrick McGarry, Gerald Brock
INTRODUCTION: Congenital hypoplasia of the distal half of the tunica albuginea has not been previously described. AIM: To review a patient presenting with erectile dysfunction secondary to congenital penile hypoplasia. METHODS: History, physical exam and penile Doppler ultrasound of the patient, followed by a discussed of treatment options and definitive management. RESULTS: Successful operative treatment of our patient with insertion of an inflatable penile prosthesis...
August 2, 2018: Sexual Medicine
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