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https://www.readbyqxmd.com/read/28430821/dietary-dha-epa-ratio-affected-tissue-fatty-acid-profiles-antioxidant-capacity-hematological-characteristics-and-expression-of-lipid-related-genes-but-not-growth-in-juvenile-black-seabream-acanthopagrus-schlegelii
#1
Min Jin, Óscar Monroig, You Lu, Ye Yuan, Yi Li, Liyun Ding, Douglas R Tocher, Qicun Zhou
An 8-week feeding trial was conducted to investigate the effects of dietary docosahexaenoic to eicosapentaenoic acid ratio (DHA/EPA) on growth performance, fatty acid profiles, antioxidant capacity, hematological characteristics and expression of some lipid metabolism related genes of juvenile black seabream (Acanthopagrus schlegelii) of initial weight 9.47 ± 0.03 g. Five isonitrogenous and isolipidic diets (45% crude protein and 14% crude lipid) were formulated to contain graded DHA/EPA ratios of 0.65, 1...
2017: PloS One
https://www.readbyqxmd.com/read/28429398/efficacy-of-passive-sampler-collection-for-atmospheric-no2-isotopes-under-simulated-environmental-conditions
#2
Justin G Coughlin, Zhongjie Yu, Emily M Elliott
RATIONALE: Nitrogen oxides or NOx (NOx  = NO + NO2 ) play an important role in air quality, atmospheric chemistry, and climate. The isotopic compositions of anthropogenic and natural NO2 sources are wide-ranging, and they can be used to constrain sources of ambient NO2 and associated atmospheric deposition of nitrogen compounds. While passive sample collection of NO2 isotopes has been used in field studies to determine NOx source influences on atmospheric deposition, this approach has not been evaluated for accuracy or precision under different environmental conditions...
April 20, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28427779/fish-oil-lc-pufas-do-not-affect-blood-coagulation-parameters-and-bleeding-manifestations-analysis-of-8-clinical-studies-with-selected-patient-groups-on-omega-3-enriched-medical-nutrition
#3
Stephanie Jeansen, Renger F Witkamp, Jossie A Garthoff, Ardy van Helvoort, Philip C Calder
BACKGROUND & AIMS: The increased consumption of fish oil enriched-products exposes a wide diversity of people, including elderly and those with impaired health to relatively high amounts of n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs). There is an ongoing debate around the possible adverse effects of n-3 LC-PUFAs on bleeding risk, particularly relevant in people with a medical history of cardiovascular events or using antithrombotic drugs. METHODS: This analysis of 8 clinical intervention studies conducted with enteral medical nutrition products containing fish oil as a source of n-3 LC-PUFAs addresses the occurrence of bleeding-related adverse events and effects on key coagulation parameters (Prothrombin Time [PT], (activated) and Partial Thromboplastin Time [(a)PTT])...
March 29, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28426875/bisphenol-a-activates-egfr-and-erk-promoting-proliferation-tumor-spheroid-formation-and-resistance-to-egfr-pathway-inhibition-in-estrogen-receptor-negative-inflammatory-breast-cancer-cells
#4
Scott J Sauer, Michael Tarpley, Imran Shah, Akshay V Save, H Kim Lyerly, Steven R Patierno, Kevin P Williams, Gayathri R Devi
Emerging evidence from epidemiological studies suggests a link between environmental chemical exposure and progression of aggressive breast cancer subtypes. Of all clinically distinct types of breast cancers, the most lethal phenotypic variant is inflammatory breast cancer (IBC). Overexpression of epidermal growth factor receptors (EGFR/HER2) along with estrogen receptor (ER) negativity is common in IBC tumor cells, which instead of a solid mass present as rapidly proliferating diffuse tumor cell clusters. Our previous studies have demonstrated a role of an adaptive response of increased antioxidants in acquired resistance to EGFR-targeting drugs in IBC...
March 1, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/28424185/very-long-chain-%C3%AF-3-fatty-acid-supplements-and-adipose-tissue-functions-a-randomized-controlled-trial
#5
Kazanna C Hames, Maria Morgan-Bathke, Debra A Harteneck, Lendia Zhou, John D Port, Ian R Lanza, Michael D Jensen
Background: Increased omega-3 (n-3) fatty acid consumption is reported to benefit patients with metabolic syndrome, possibly due to improved adipose tissue function.Objective: We tested the effects of high-dose, very-long-chain ω-3 fatty acids on adipose tissue inflammation and insulin regulation of lipolysis.Design: A double-blind, placebo-controlled study compared 6 mo of 3.9 g eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)/d (4.2 g total ω-3/d; n = 12) with a placebo (4.2 g oleate/d; n = 9) in insulin-resistant adults...
April 19, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28418663/airborne-quantification-of-methane-emissions-over-the-four-corners-region
#6
Mackenzie L Smith, Alexander Gvakharia, Eric A Kort, Colm Sweeney, Stephen A Conley, Ian C Faloona, Tim Newberger, Russell Schnell, Stefan Schwietzke, Sonja Wolter
Methane (CH4) is a potent greenhouse gas and the primary component of natural gas. The San Juan Basin (SJB) is one of the largest coal-bed methane producing regions in North America and, including gas production from conventional and shale sources, contributes ~2% of U.S. natural gas production in 2015. In this work, we quantify the CH4 flux from the SJB using continuous atmospheric sampling from aircraft collected during the TOPDOWN2015 field campaign in April 2015. Using five independent days of measurements and the aircraft-based mass balance method, we calculate an average CH4 flux of 0...
April 18, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28417329/quantitative-cancer-risk-assessment-and-local-mortality-burden-for-ambient-air-pollution-in-an-eastern-mediterranean-city
#7
Hassan R Dhaini, Thérèse Salameh, Antoine Waked, Stéphane Sauvage, Agnès Borbon, Paola Formenti, Jean-François Doussin, Nadine Locoge, Charbel Afif
Health risks posed by ambient air pollutants to the urban Lebanese population have not been well characterized. The aim of this study is to assess cancer risk and mortality burden of non-methane hydrocarbons (NMHCs) and particulates (PM) based on two field-sampling campaigns conducted during summer and winter seasons in Beirut. Seventy NMHCs were analyzed by TD-GC-FID. PM2.5 elemental carbon (EC) components were examined using a Lab OC-EC aerosol Analyzer, and polycyclic aromatic hydrocarbons were analyzed by GC-MS...
April 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28416862/biscuits-fortified-with-micro-encapsulated-shrimp-oil-characteristics-and-storage-stability
#8
Sirima Takeungwongtrakul, Soottawat Benjakul
Characteristics and storage stability of biscuits fortified with micro-encapsulated shrimp oil (MSO) were determined. The addition of MSO increased spread ratio, whilst decreased the thickness of biscuit. The highest hardness of biscuit was obtained with addition of 9 or 12% MSO. Biscuit surface showed higher redness and yellowness when MSO was incorporated (p < 0.05). The addition of MSO up to 6% had no adverse effect on biscuit quality and acceptability. When biscuits added with 6% MSO were stored under different illumination conditions (light and dark), lipid oxidation in all samples increased throughout the storage of 12 days...
April 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28416223/study-on-emission-of-hazardous-trace-elements-in-a-350%C3%A2-mw-coal-fired-power-plant-part-2-arsenic-chromium-barium-manganese-lead
#9
Shilin Zhao, Yufeng Duan, Lei Chen, Yaning Li, Ting Yao, Shuai Liu, Meng Liu, Jianhong Lu
Hazardous Trace elements (HTEs) emitted from coal combustion has raised widespread concern. Studies on the emission characteristics of five HTEs, namely arsenic (As), chromium (Cr), barium (Ba), manganese (Mn), lead (Pb) at three different loads (100%, 83%, 71% output) and different coal types were performed on a 350 MW coal-fired power plant equipped with SCR, ESP + FF, and WFGD. HTEs in the flue gas at the inlet/outlet of each air pollution control device (APCD) were sampled simultaneously based on US EPA Method 29...
April 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28413805/release-of-airborne-polychlorinated-biphenyls-from-new-bedford-harbor-results-in-elevated-concentrations-in-the-surrounding-air
#10
Andres Martinez, Bailey N Hadnott, Andrew M Awad, Nicholas J Herkert, Kathryn Tomsho, Komal Basra, Madeleine K Scammell, Wendy Heiger-Bernays, Keri C Hornbuckle
Qualitatively and quantitatively, we have demonstrated that airborne polychlorinated biphenyl (PCB) concentrations in the air surrounding New Bedford Harbor (NBH) are caused by its water PCB emissions. We measured airborne PCBs at 18 homes and businesses near NBH in 2015, with values ranging from 0.4 to 38 ng m(-3), with a very strong Aroclor 1242/1016 signal that is most pronounced closest to the harbor and reproducible over three sampling rounds. Using U.S. Environmental Protection Agency (U.S. EPA) water PCB data from 2015 and local meteorology, we predicted gas-phase fluxes of PCBs from 160 to 1200 μg m(-2) day(-1)...
April 11, 2017: Environmental Science & Technology Letters
https://www.readbyqxmd.com/read/28411052/selective-enrichment-of-eicosapentaenoic-acid-20-5n-3-in-n-oceanica-casa-cc201-by-natural-auxin-supplementation
#11
Aswathy Udayan, Muthu Arumugam
The present study aims to evaluate the effect of different concentration of natural auxin, Indole-3 acetic acid (IAA) on growth, lipid yield, PUFA and EPA accumulation in Nannochloropsis oceanica CASA CC201. It was observed that the, treatment with 10ppm concentration of IAA resulted in high cell number 579.5×10(6)cells/ml than the control (215.5×10(6)cells/ml). Treatment with IAA at a concentration of 40ppm gives the highest cellular lipid accumulation of 60.9% DCW than the control 31.05% DCW). Lipid yield is also found to be increased by the addition of 40ppm IAA (319...
March 27, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28410668/lipid-correlates-of-antidepressant-response-to-omega-3-polyunsaturated-fatty-acid-supplementation-a-pilot-study
#12
Licinia Ganança, Hanga C Galfalvy, Maria A Oquendo, Adrienne Hezghia, Thomas B Cooper, J John Mann, M Elizabeth Sublette
Low omega-3 polyunsaturated fatty acid (PUFA) levels are seen in major depression. We examined effects of six weeks of fish oil supplementation on clinical characteristics in 16 patients with symptomatic major depressive disorder, and tested plasma phospholipid levels of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) as correlates of clinical response. Depression symptoms improved after supplementation (p=0.007). The reduction in depression severity was not predicted by baseline PUFA levels but did exhibit a relationship with endpoint PUFAs, correlating negatively with DHA as a percentage of plasma phospholipids (DHA%; R(2)=0...
April 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28410665/impact-of-dietary-precursor-ala-versus-preformed-dha-on-fatty-acid-profiles-of-eggs-liver-and-adipose-tissue-and-expression-of-genes-associated-with-hepatic-lipid-metabolism-in-laying-hens
#13
M Neijat, P Eck, J D House
Dietary omega-3 polyunsaturated fatty acids (n-3 PUFA), including alpha-linolenic acid (ALA) and preformed longer chain PUFA (LCPUFA, particularly docosahexaenoic acid, DHA) differ in their egg LCPUFA enrichment efficiency. However, mechanisms leading to these differences are unclear. To this end, omega-3 PUFA contents in different lipid classes, including triacylglycerol (TAG) and total phospholipid (PL) in yolk, liver and adipose, as well as the expression of key hepatic enzymes in lipid metabolism were evaluated in laying hens in response to changes in dietary supply...
April 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28410617/treatment-with-high-dose-n-3-pufas-has-no-effect-on-platelet-function-coagulation-metabolic-status-or-inflammation-in-patients-with-atherosclerosis-and-type-2-diabetes
#14
Malgorzata Poreba, Magdalena Mostowik, Aleksander Siniarski, Renata Golebiowska-Wiatrak, Krzysztof Piotr Malinowski, Maciej Haberka, Ewa Konduracka, Jadwiga Nessler, Anetta Undas, Grzegorz Gajos
BACKGROUND: Despite numerous studies on cardioprotective effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), there is limited evidence for n-3 PUFA-mediated effects, especially at its higher dose, on cardiovascular risk in patients with type 2 diabetes (DM2) and established atherosclerosis. PURPOSE: To investigate the effect of daily treatment with a higher dose (2 g) of n-3 PUFAs on platelet function, coagulation parameters, fibrin clot properties, markers of systemic inflammation and metabolic status, in patients with atherosclerotic vascular disease and DM2 who receive optimal medical therapy...
April 14, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28409430/spatio-temporal-distribution-of-metals-in-household-dust-from-rural-semi-urban-and-urban-environments-in-the-niger-delta-nigeria
#15
Chukwujindu M A Iwegbue, Ejiro C Oliseyenum, Bice S Martincigh
Concentrations of metals in household dust samples from rural, semi-urban and urban zones of the Niger Delta in Nigeria were measured during both 2009 and 2014 with the aim of providing information on changes in the concentrations, distribution patterns, sources and risks of metals in these zones. The concentrations of metals in the dust samples were quantified by using inductively coupled plasma atomic emission spectrophotometry (ICP-AES) after digestion with aqua regia. The measured concentrations (mg kg(-1)) of metals in the three zones within the study periods were as follows: <LOQ-21...
April 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28409336/dietary-docosahexaenoic-acid-and-trans-10-cis-12-conjugated-linoleic-acid-differentially-alter-oxylipin-profiles-in-mouse-periuterine-adipose-tissue
#16
Yuriko Adkins, Benjamin J Belda, Theresa L Pedersen, Dawn M Fedor, Bruce E Mackey, John W Newman, Darshan S Kelley
Diets containing high n-3 polyunsaturated fatty acids (PUFA) decrease inflammation and the incidence of chronic diseases including cardiovascular disease and nonalcoholic fatty liver disease while trans-fatty acids (TFA) intake increases the incidence of these conditions. Some health benefits of n-3 PUFA are mediated through the impact of their oxygenated metabolites, i.e. oxylipins. The TFA, trans-10, cis-12-conjugated linoleic acid (CLA; 18:2n-6) is associated with adipose tissue (AT) inflammation, oxidative stress, and wasting...
April 13, 2017: Lipids
https://www.readbyqxmd.com/read/28407570/the-application-of-illite-supported-nanoscale-zero-valent-iron-for-the-treatment-of-uranium-contaminated-groundwater
#17
C Jing, S Landsberger, Y L Li
In this study, nanoscale zero valent iron I-NZVI was investigated as a remediation strategy for uranium contaminated groundwater from the former Cimarron Fuel Fabrication Site in Oklahoma, USA. The 1 L batch-treatment system was applied in the study. The result shows that 99.9% of uranium in groundwater was removed by I-NZVI within 2 h. Uranium concentration in the groundwater stayed around 27 μg/L, and there was no sign of uranium release into groundwater after seven days of reaction time. Meanwhile the release of iron was significantly decreased compared to NZVI which can reduce the treatment impact on the water environment...
April 10, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28405785/determination-of-the-potential-implementation-impact-of-2016-ministry-of-environmental-protection-generic-assessment-criteria-for-potentially-contaminated-sites-in-china
#18
Yuanyuan Cheng, Yu-Ting Tang, C Paul Nathanail
The Ministry of Environmental Protection of China issued a 3rd draft edition of risk-based Generic Assessment Criteria (the MEP-GAC) in March 2016. Since these will be the first authoritative GAC in China, their implementation is likely to have a significant impact on China's growing contaminated land management sector. This study aims to determine the potential implementation impact of the MEP-GAC through an in-depth analysis of the management context, land use scenarios, health criteria values adopted and exposure pathways considered...
April 12, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28403232/an-oil-containing-epa-and-dha-from-transgenic-camelina-sativa-to-replace-marine-fish-oil-in-feeds-for-atlantic-salmon-salmo-salar-l-effects-on-intestinal-transcriptome-histology-tissue-fatty-acid-profiles-and-plasma-biochemistry
#19
Mónica B Betancor, Keshuai Li, Matthew Sprague, Tora Bardal, Olga Sayanova, Sarah Usher, Lihua Han, Kjell Måsøval, Ole Torrissen, Johnathan A Napier, Douglas R Tocher, Rolf Erik Olsen
New de novo sources of omega 3 (n-3) long chain polyunsaturated fatty acids (LC-PUFA) are required as alternatives to fish oil in aquafeeds in order to maintain adequate levels of the beneficial fatty acids, eicosapentaenoic and docosahexaenoic (EPA and DHA, respectively). The present study investigated the use of an EPA+DHA oil derived from transgenic Camelina sativa in Atlantic salmon (Salmo salar) feeds containing low levels of fishmeal (35%) and fish oil (10%), reflecting current commercial formulations, to determine the impacts on tissue fatty acid profile, intestinal transcriptome, and health of farmed salmon...
2017: PloS One
https://www.readbyqxmd.com/read/28403203/dynamics-of-triacylglycerol-and-epa-production-in-phaeodactylum-tricornutum-under-nitrogen-starvation-at-different-light-intensities
#20
Ilse M Remmers, Dirk E Martens, René H Wijffels, Packo P Lamers
Lipid production in microalgae is highly dependent on the applied light intensity. However, for the EPA producing model-diatom Phaeodactylum tricornutum, clear consensus on the impact of incident light intensity on lipid productivity is still lacking. This study quantifies the impact of different incident light intensities on the biomass, TAG and EPA yield on light in nitrogen starved batch cultures of P. tricornutum. The maximum biomass concentration and maximum TAG and EPA contents were found to be independent of the applied light intensity...
2017: PloS One
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